KR101137467B1 - 테오브로민 함유 서방성 정제 - Google Patents

테오브로민 함유 서방성 정제 Download PDF

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Publication number
KR101137467B1
KR101137467B1 KR1020090105137A KR20090105137A KR101137467B1 KR 101137467 B1 KR101137467 B1 KR 101137467B1 KR 1020090105137 A KR1020090105137 A KR 1020090105137A KR 20090105137 A KR20090105137 A KR 20090105137A KR 101137467 B1 KR101137467 B1 KR 101137467B1
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KR
South Korea
Prior art keywords
theobromine
weight
sustained
release
release layer
Prior art date
Application number
KR1020090105137A
Other languages
English (en)
Korean (ko)
Other versions
KR20110048367A (ko
Inventor
어진
김창환
한창균
정현근
김양중
김종걸
윤주용
이정화
Original Assignee
안국약품 주식회사
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 안국약품 주식회사 filed Critical 안국약품 주식회사
Priority to KR1020090105137A priority Critical patent/KR101137467B1/ko
Priority to TR2012/05029T priority patent/TR201205029T1/xx
Priority to CN201080051266.9A priority patent/CN102711740B/zh
Priority to RU2012119070/15A priority patent/RU2506947C2/ru
Priority to UAA201206606A priority patent/UA103558C2/ru
Priority to BR112012010325A priority patent/BR112012010325B8/pt
Priority to PCT/KR2010/005911 priority patent/WO2011052884A2/ko
Publication of KR20110048367A publication Critical patent/KR20110048367A/ko
Application granted granted Critical
Publication of KR101137467B1 publication Critical patent/KR101137467B1/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
KR1020090105137A 2009-11-02 2009-11-02 테오브로민 함유 서방성 정제 KR101137467B1 (ko)

Priority Applications (7)

Application Number Priority Date Filing Date Title
KR1020090105137A KR101137467B1 (ko) 2009-11-02 2009-11-02 테오브로민 함유 서방성 정제
TR2012/05029T TR201205029T1 (tr) 2009-11-02 2010-09-01 Teobromin içeren yavaş salınımlı tablet.
CN201080051266.9A CN102711740B (zh) 2009-11-02 2010-09-01 含可可碱的缓释锭剂
RU2012119070/15A RU2506947C2 (ru) 2009-11-02 2010-09-01 Таблетка пролонгированного высвобождения, содержащая теобромин
UAA201206606A UA103558C2 (ru) 2009-11-02 2010-09-01 Таблетка пролонгированного высвобождения, которая содержит теобромин
BR112012010325A BR112012010325B8 (pt) 2009-11-02 2010-09-01 comprimido com liberação sustentada e imediata de teobromina
PCT/KR2010/005911 WO2011052884A2 (ko) 2009-11-02 2010-09-01 테오브로민 함유 서방성 정제

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020090105137A KR101137467B1 (ko) 2009-11-02 2009-11-02 테오브로민 함유 서방성 정제

Publications (2)

Publication Number Publication Date
KR20110048367A KR20110048367A (ko) 2011-05-11
KR101137467B1 true KR101137467B1 (ko) 2012-04-20

Family

ID=43922740

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020090105137A KR101137467B1 (ko) 2009-11-02 2009-11-02 테오브로민 함유 서방성 정제

Country Status (7)

Country Link
KR (1) KR101137467B1 (ru)
CN (1) CN102711740B (ru)
BR (1) BR112012010325B8 (ru)
RU (1) RU2506947C2 (ru)
TR (1) TR201205029T1 (ru)
UA (1) UA103558C2 (ru)
WO (1) WO2011052884A2 (ru)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101220830B1 (ko) * 2010-08-18 2013-01-10 안국약품 주식회사 테오브로민의 서방성 과립제 및 그 제조방법

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20060113728A (ko) * 2003-11-13 2006-11-02 룀 게엠베하 조절 물질의 전달에 영향을 미치는 매트릭스를 갖는 다층약제학적 형태
KR20070078625A (ko) * 2006-01-27 2007-08-01 씨제이 주식회사 멀티플 유닛 타입 서방성 경구 제제 및 그 제조방법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070196481A1 (en) * 2002-07-25 2007-08-23 Amidon Gregory E Sustained-release tablet composition
KR20070017335A (ko) * 2004-03-22 2007-02-09 노파르티스 아게 리카르바제핀을 포함하는 경구투여용 매트릭스 제제
BRPI0609505A2 (pt) * 2005-03-29 2010-04-13 Rihm Gmbh forma farmacêutica em multipartìculas compreendendo péletes com uma matriz que influencia o fornecimento de uma substáncia moduladora

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20060113728A (ko) * 2003-11-13 2006-11-02 룀 게엠베하 조절 물질의 전달에 영향을 미치는 매트릭스를 갖는 다층약제학적 형태
KR20070078625A (ko) * 2006-01-27 2007-08-01 씨제이 주식회사 멀티플 유닛 타입 서방성 경구 제제 및 그 제조방법

Also Published As

Publication number Publication date
BR112012010325A2 (pt) 2016-03-29
WO2011052884A2 (ko) 2011-05-05
CN102711740A (zh) 2012-10-03
RU2012119070A (ru) 2013-12-10
WO2011052884A3 (ko) 2011-07-14
BR112012010325B8 (pt) 2021-05-25
RU2506947C2 (ru) 2014-02-20
KR20110048367A (ko) 2011-05-11
UA103558C2 (ru) 2013-10-25
BR112012010325B1 (pt) 2021-01-26
TR201205029T1 (tr) 2012-09-21
CN102711740B (zh) 2014-02-12

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