KR101130191B1 - 세포 바이오매스로부터 폴리하이드록시알카노에이트(˝phas˝) 를 회수하는 방법 - Google Patents

세포 바이오매스로부터 폴리하이드록시알카노에이트(˝phas˝) 를 회수하는 방법 Download PDF

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KR101130191B1
KR101130191B1 KR1020067012268A KR20067012268A KR101130191B1 KR 101130191 B1 KR101130191 B1 KR 101130191B1 KR 1020067012268 A KR1020067012268 A KR 1020067012268A KR 20067012268 A KR20067012268 A KR 20067012268A KR 101130191 B1 KR101130191 B1 KR 101130191B1
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pha
solvent
biomass
suspension
cell biomass
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KR20060134005A (ko
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파울루 에두아르도 만텔라토
알바로 민토 두찌
테투히코 사토
나자레노 안토니오 세토리 두라오
로베르토 비안나 노나토
카를로 로치씨올리
소니아 마리아 케세린지
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피에이치비 인더스트리얼 에스.에이.
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    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/88Post-polymerisation treatment
    • C08G63/90Purification; Drying
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/88Post-polymerisation treatment
    • C08G63/89Recovery of the polymer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/62Carboxylic acid esters
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/62Carboxylic acid esters
    • C12P7/625Polyesters of hydroxy carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/06Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
KR1020067012268A 2003-11-28 2004-11-25 세포 바이오매스로부터 폴리하이드록시알카노에이트(˝phas˝) 를 회수하는 방법 Expired - Fee Related KR101130191B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
BR0306230 2003-11-28
BRPI0306230-9 2003-11-28
BRPI0405622-1 2004-11-19
BRPI0405622-1A BRPI0405622B1 (pt) 2004-11-19 2004-11-19 PROCESSO PARA RECUPERAÇÃO DE POLIHIDROXIALCANOATOS (PHAs) DE BIOMASSA CELULAR
PCT/BR2004/000237 WO2005052175A2 (en) 2003-11-28 2004-11-25 Process for recovering polyhydroxialkanoates ('phas') from cellular biomass

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KR20060134005A KR20060134005A (ko) 2006-12-27
KR101130191B1 true KR101130191B1 (ko) 2012-03-29

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US (1) US9045595B2 (enExample)
EP (1) EP1687436B1 (enExample)
JP (1) JP4709766B2 (enExample)
KR (1) KR101130191B1 (enExample)
CN (1) CN1886517B (enExample)
AU (1) AU2004293501B2 (enExample)
CA (1) CA2547689C (enExample)
DE (1) DE602004018971D1 (enExample)
ES (1) ES2319537T3 (enExample)
PT (1) PT1687436E (enExample)
WO (1) WO2005052175A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025058384A1 (ko) * 2023-09-12 2025-03-20 씨제이제일제당(주) 폴리-4-하이드록시부티레이트를 포함하는 바이오매스의 회수 방법
KR102915476B1 (ko) 2023-09-12 2026-01-19 씨제이제일제당(주) 폴리-4-하이드록시부티레이트를 포함하는 바이오매스의 회수 방법

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10435297B2 (en) 1999-06-16 2019-10-08 Ardica Technologies, Inc. Crystallization and stabilization in the synthesis of microcrystalline alpha alane
US10233079B2 (en) * 1999-06-16 2019-03-19 Ardica Technologies, Inc. Heating methods for aluminum hydride production
EP1688450B2 (en) * 2003-11-21 2012-08-01 Kaneka Corporation Process for producing polyhydroxyalkanoate crystal
TW200613560A (en) 2004-06-29 2006-05-01 Procter & Gamble Solvent extraction of polyhydroxyalkanoates from biomass
AU2005285271B2 (en) 2004-09-13 2010-09-09 Metabolix, Inc. Single solvent polymer extraction methods
BRPI0501844B1 (pt) * 2005-03-04 2019-12-24 Phb Ind S/A processo para extração e recuperação de polihidroxialcanoatos (phas) a partir de uma biomassa celular bacteriana
EP1979394A1 (de) * 2006-01-17 2008-10-15 Basf Se Verfahren zur gewinnung von polyhydroxyalkanoaten mit vermindertem gehalt an alkali- und erdalkalimetallen und erhöhter thermischer stabilität
CN100448911C (zh) * 2006-03-06 2009-01-07 清华大学 一种提取微生物胞内聚羟基脂肪酸酯的方法
BRPI0801845B1 (pt) * 2008-06-09 2016-05-24 Citrosuco S A Agroindústria processo de obtenção de pha a partir de resíduo cítrico, pha obtido a partir de resíduo cítrico, composição polimérica contendo pha, artefato sólido contendo pha, artefato sólido contendo composição polimérica compreendendo pha, uso de resíduo cítrico para a obtenção de pha
BRPI0913675A2 (pt) 2008-07-02 2015-11-24 Basf Se método para isolar poli-hidroxialcanoatos das células de produção
EP2366794B1 (en) 2008-12-09 2017-02-22 Kaneka Corporation Method for producing poly-3-hydroxyalkanoate and agglomerate of poly-3-hydroxyalkanoate
JP5839855B2 (ja) * 2011-06-29 2016-01-06 株式会社カネカ ポリヒドロキシアルカノエートの製造方法
ES2448823B1 (es) 2012-08-14 2014-10-13 Neol Biosolutions, S.A. Producción de bioplásticos
EP2935463B1 (en) * 2012-12-18 2017-02-08 Veolia Water Solutions & Technologies Support Method of producing polyhydroxyalkanoate compounded plastics having improved mechanical properties
US9290612B2 (en) * 2013-03-13 2016-03-22 Tepha, Inc. Compositions and devices of poly-4-hydroxybutyrate
EP3065789B1 (en) 2013-11-05 2018-10-24 Tepha, Inc. Compositions and devices of poly-4-hydroxybutyrate
CZ307015B6 (cs) 2014-06-03 2017-11-15 Nafigate Corporation, A.S. Způsob izolace polyhydroxyalkanoátů z biomasy fermentované mikroorganismy produkujícími polyhydroxyalkanoáty a/nebo z biomasy obsahující alespoň jednu plodinu produkující polyhydroxyalkanoáty
WO2018070492A1 (ja) * 2016-10-13 2018-04-19 株式会社カネカ ポリヒドロキシアルカン酸の製造方法
CN109504715A (zh) * 2017-09-15 2019-03-22 北京蓝晶微生物科技有限公司 一种制备聚羟基脂肪酸酯(pha)的方法
FR3080033B1 (fr) * 2018-04-12 2020-07-17 Societe D'exploitation De Produits Pour Les Industries Chimiques Seppic Nouvelle composition a base d'acides polycafeoylquiniques, son utilisation en cosmetique et compositions cosmetiques en comprenant
CN113330068A (zh) * 2018-08-24 2021-08-31 墨哈拉姆企业有限公司 可生物降解的聚合物组合物及其制备方法
CN109517156A (zh) * 2019-01-02 2019-03-26 清华大学 一种聚羟基脂肪酸酯的纯化方法
EP4114203A1 (en) 2020-03-05 2023-01-11 VitaNav, Inc. COMPOSITION OF (D)-ß-HYDROXYBUTYRIC ACID, (D)-ß-HYDROXYVALERIC ACID, AND (D)-1,3 BUTANEDIOL AS A NUTRITIONAL SUPPLEMENT AND THERAPEUTIC AGENT
CN111647151B (zh) * 2020-06-10 2022-09-23 珠海麦得发生物科技股份有限公司 一种高效全自动二次纯化pha的工艺
US11078328B1 (en) 2020-10-30 2021-08-03 Robert Whitehouse Sequestered amorphous polyhydroxyalkanoate polymer (SAPP) material derived from cellular biomass and production thereof
US11104761B1 (en) 2020-10-30 2021-08-31 Robert Whitehouse Sequestered amorphous polyhydroxyalkanoate polymer (SAPP) material derived from cellular biomass and production thereof
BR112023024355A2 (pt) * 2021-06-28 2024-02-06 Phb Ind S/A Processo para produzir misturas opticamente ativas de (r)-3-hidroxibutirato e (r)-3-hidroxivalerato e método para tratar um indivíduo tendo uma doença metabólica
ES2936907B2 (es) * 2021-09-14 2023-08-11 Quim Tecnica Ecologica S L U Metodo y equipos para la produccion de polihidroxialcanoatos y bioestimulante radicular a partir de residuos organicos
KR102548122B1 (ko) * 2021-09-29 2023-06-28 한국에너지공과대학교 폴리하이드록시 알카노에이트의 제조방법, 이를 이용하여 제조된 폴리하이드록시 알카노에이트 및 폴리하이드록시 알카노에이트 제조용 건식 발효조
KR102810479B1 (ko) * 2022-08-04 2025-05-21 씨제이제일제당(주) 색가 모니터링을 통한 정제 공정 제어 방법 및 시스템, 및 폴리하이드록시알카노에이트 수지의 제조 방법
ES3014636B2 (es) * 2023-10-18 2025-10-06 Quim Tecnica Ecologica S L U Metodo y equipos para la produccion de fertilizantes de uso agricola y bioplastico microbiano a partir de residuos organicos
KR20250055782A (ko) 2023-10-18 2025-04-25 경희대학교 산학협력단 메탄자화균으로부터 폴리하이드록시알카노에이트를 추출 및 회수하는 방법
AR131698A1 (es) 2024-01-25 2025-04-23 Ingenieria Metabolica S A Proceso de producción y purificación económica de polihidroxibutirato (phb) de elevada pureza a partir de bacterias genéticamente modificadas

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3044942A (en) * 1960-09-27 1962-07-17 Grace W R & Co Process for preparing poly-beta-hydroxybutyric acid
US3107172A (en) * 1960-12-30 1963-10-15 Grace W R & Co Molded product containing poly-beta-hydroxybutyric acid and method of making
US3275610A (en) * 1964-03-24 1966-09-27 Mobil Oil Corp Microbial synthesis of polymers
FR2446859A1 (fr) * 1979-01-22 1980-08-14 Solvay Procede de separation de poly-b-hydroxybutyrates d'une biomasse
EP0015123B1 (en) 1979-02-21 1982-12-22 Imperial Chemical Industries Plc A process for the extraction of poly-3-hydroxy-butyric acid from microbial cells
US4265770A (en) * 1979-11-09 1981-05-05 Amstar Corporation Separation of suspended solids from phosphate tailings
GB8311677D0 (en) * 1983-04-28 1983-06-02 Ici Plc Extraction process
FR2567149B1 (fr) * 1984-07-06 1986-12-05 Solvay Procede pour l'extraction de poly-beta-hydroxybutyrates au moyen d'un solvant a partir d'une suspension aqueuse de micro-organismes
AT390068B (de) * 1988-07-07 1990-03-12 Danubia Petrochemie Extraktionsmittel fuer poly-d(-)-3-hydroxybuttersaeure
CA1334430C (en) * 1989-04-06 1995-02-14 Claude Chavarie Separation of poly-.beta.-hydroxyalkanoic acids from microbial biomass
AT395319B (de) * 1990-10-05 1992-11-25 Danubia Petrochem Polymere Verfahren zur gewinnung eines polyhydroxyalkanoates aus dem zellmaterial eines mikroorganismus und polyhydroxyalkanoatflocken
ES2062955B1 (es) * 1993-04-29 1995-06-16 Repsol Quimica Sa Procedimiento para la extraccion de polihidroxialcanoatos de bacterias halofilas que lo contienen.
BR9302312A (pt) * 1993-06-30 1995-02-07 Cooperativa De Produtores De C Process de extração de biopolímeros
EP0763126B1 (en) 1994-06-01 1999-07-21 The Procter & Gamble Company Process for recovering polyhydroxyalkanoates using centrifugal fractionation
NL9401037A (nl) * 1994-06-23 1996-02-01 Soonn Stichting Onderzoek En O Werkwijze voor het bereiden van een biologisch afbreekbare polyhydroxyalkanoaat coating met behulp van een waterige dispersie van polyhydroxyalkanoaat.
US5942597A (en) * 1995-08-21 1999-08-24 The Procter & Gamble Company Solvent extraction of polyhydroxyalkanoates from biomass
DE69621342T2 (de) 1995-08-21 2003-01-23 The Procter & Gamble Company, Cincinnati Vereinfachte loesungsmittelextraktion von polyhydroxyalkanoaten aus biomasse durch verwendung eines marginalen nichtloesungsmittels fuer pha
US5821299A (en) * 1996-02-16 1998-10-13 The Proctor & Gamble Company Solvent extraction of polyhydroxy-alkanoates from biomass facilitated by the use of marginal nonsolvent
DE19633475C2 (de) 1996-08-20 2002-03-14 Buna Sow Leuna Olefinverb Gmbh Verfahren zur Gewinnung von Polyhydroxyalkanoaten und deren Verwendung
AU6971598A (en) * 1997-04-15 1998-11-11 Monsanto Company Methods of pha extraction and recovery using non-halogenated solvents
US6087471A (en) * 1997-04-15 2000-07-11 Monsanto Company High temperature PHA extraction using PHA-poor solvents
DE69942060D1 (de) * 1998-04-08 2010-04-08 Metabolix Inc Verfahren für die trennung und reinigung von biopolymeren
WO1999064498A1 (en) * 1998-06-09 1999-12-16 Metabolix, Inc. Methods and apparatus for the production of amorphous polymer suspensions
AU2001250800A1 (en) * 2000-03-10 2001-09-24 Metabolix, Inc. Prevention of gelation of polyhydroxyalkanoate solutions using shear
JP4336509B2 (ja) 2003-03-07 2009-09-30 キヤノン株式会社 処理方法及びシステム
BRPI0501844B1 (pt) * 2005-03-04 2019-12-24 Phb Ind S/A processo para extração e recuperação de polihidroxialcanoatos (phas) a partir de uma biomassa celular bacteriana

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025058384A1 (ko) * 2023-09-12 2025-03-20 씨제이제일제당(주) 폴리-4-하이드록시부티레이트를 포함하는 바이오매스의 회수 방법
KR102915476B1 (ko) 2023-09-12 2026-01-19 씨제이제일제당(주) 폴리-4-하이드록시부티레이트를 포함하는 바이오매스의 회수 방법

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Publication number Publication date
EP1687436B1 (en) 2009-01-07
AU2004293501B2 (en) 2009-10-29
CA2547689A1 (en) 2005-06-09
WO2005052175A2 (en) 2005-06-09
US20070161096A1 (en) 2007-07-12
ES2319537T3 (es) 2009-05-08
DE602004018971D1 (de) 2009-02-26
KR20060134005A (ko) 2006-12-27
PT1687436E (pt) 2009-03-05
JP2007512007A (ja) 2007-05-17
CN1886517A (zh) 2006-12-27
JP4709766B2 (ja) 2011-06-22
US9045595B2 (en) 2015-06-02
CA2547689C (en) 2014-10-21
CN1886517B (zh) 2013-07-17
AU2004293501A1 (en) 2005-06-09
EP1687436A2 (en) 2006-08-09
WO2005052175A3 (en) 2005-06-30

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