ES2319537T3 - Proceso de recuperacion de polihidroxialcanoatos (phas) procedentes de una biomasa celular. - Google Patents
Proceso de recuperacion de polihidroxialcanoatos (phas) procedentes de una biomasa celular. Download PDFInfo
- Publication number
- ES2319537T3 ES2319537T3 ES04797154T ES04797154T ES2319537T3 ES 2319537 T3 ES2319537 T3 ES 2319537T3 ES 04797154 T ES04797154 T ES 04797154T ES 04797154 T ES04797154 T ES 04797154T ES 2319537 T3 ES2319537 T3 ES 2319537T3
- Authority
- ES
- Spain
- Prior art keywords
- pha
- biomass
- solvent
- suspension
- phase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000002028 Biomass Substances 0.000 title claims abstract description 225
- 230000001413 cellular effect Effects 0.000 title claims abstract description 40
- 238000011084 recovery Methods 0.000 title claims abstract description 35
- 239000005014 poly(hydroxyalkanoate) Substances 0.000 claims abstract description 254
- 229920000903 polyhydroxyalkanoate Polymers 0.000 claims abstract description 254
- 208000037534 Progressive hemifacial atrophy Diseases 0.000 claims abstract description 197
- 239000002904 solvent Substances 0.000 claims abstract description 179
- 238000000034 method Methods 0.000 claims abstract description 124
- 230000008569 process Effects 0.000 claims abstract description 114
- 239000000725 suspension Substances 0.000 claims abstract description 113
- 238000000605 extraction Methods 0.000 claims abstract description 112
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 100
- 238000001704 evaporation Methods 0.000 claims abstract description 36
- 230000008020 evaporation Effects 0.000 claims abstract description 36
- 239000000243 solution Substances 0.000 claims abstract description 33
- 238000001914 filtration Methods 0.000 claims abstract description 29
- 238000000926 separation method Methods 0.000 claims abstract description 27
- 239000002245 particle Substances 0.000 claims abstract description 23
- 230000001580 bacterial effect Effects 0.000 claims abstract description 18
- 238000001816 cooling Methods 0.000 claims abstract description 15
- 238000000855 fermentation Methods 0.000 claims abstract description 13
- 230000004151 fermentation Effects 0.000 claims abstract description 13
- 238000010438 heat treatment Methods 0.000 claims abstract description 12
- 239000012535 impurity Substances 0.000 claims abstract description 12
- 238000002347 injection Methods 0.000 claims abstract description 11
- 239000007924 injection Substances 0.000 claims abstract description 11
- 239000008187 granular material Substances 0.000 claims abstract description 10
- 239000012141 concentrate Substances 0.000 claims abstract description 9
- 238000005406 washing Methods 0.000 claims abstract description 8
- 238000013019 agitation Methods 0.000 claims abstract description 7
- 238000004090 dissolution Methods 0.000 claims abstract description 7
- 239000007900 aqueous suspension Substances 0.000 claims abstract description 6
- 239000013557 residual solvent Substances 0.000 claims abstract description 6
- 229920000070 poly-3-hydroxybutyrate Polymers 0.000 claims description 157
- 239000012071 phase Substances 0.000 claims description 103
- PHTQWCKDNZKARW-UHFFFAOYSA-N isoamylol Chemical compound CC(C)CCO PHTQWCKDNZKARW-UHFFFAOYSA-N 0.000 claims description 50
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 41
- 239000012528 membrane Substances 0.000 claims description 34
- 239000000463 material Substances 0.000 claims description 29
- ZSIAUFGUXNUGDI-UHFFFAOYSA-N hexan-1-ol Chemical compound CCCCCCO ZSIAUFGUXNUGDI-UHFFFAOYSA-N 0.000 claims description 28
- 239000002244 precipitate Substances 0.000 claims description 19
- UHOPWFKONJYLCF-UHFFFAOYSA-N 2-(2-sulfanylethyl)isoindole-1,3-dione Chemical compound C1=CC=C2C(=O)N(CCS)C(=O)C2=C1 UHOPWFKONJYLCF-UHFFFAOYSA-N 0.000 claims description 18
- 235000000346 sugar Nutrition 0.000 claims description 17
- 229920000642 polymer Polymers 0.000 claims description 16
- 238000001471 micro-filtration Methods 0.000 claims description 15
- 239000000203 mixture Substances 0.000 claims description 15
- DKPFZGUDAPQIHT-UHFFFAOYSA-N Butyl acetate Natural products CCCCOC(C)=O DKPFZGUDAPQIHT-UHFFFAOYSA-N 0.000 claims description 14
- 239000003795 chemical substances by application Substances 0.000 claims description 14
- FUZZWVXGSFPDMH-UHFFFAOYSA-N hexanoic acid Chemical compound CCCCCC(O)=O FUZZWVXGSFPDMH-UHFFFAOYSA-N 0.000 claims description 14
- 239000007788 liquid Substances 0.000 claims description 14
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 claims description 13
- AMQJEAYHLZJPGS-UHFFFAOYSA-N N-Pentanol Chemical compound CCCCCO AMQJEAYHLZJPGS-UHFFFAOYSA-N 0.000 claims description 13
- 239000000843 powder Substances 0.000 claims description 13
- 150000001875 compounds Chemical class 0.000 claims description 12
- 238000005189 flocculation Methods 0.000 claims description 12
- 230000016615 flocculation Effects 0.000 claims description 12
- 239000012808 vapor phase Substances 0.000 claims description 11
- 238000001035 drying Methods 0.000 claims description 10
- 239000002699 waste material Substances 0.000 claims description 10
- QPRQEDXDYOZYLA-UHFFFAOYSA-N 2-methylbutan-1-ol Chemical compound CCC(C)CO QPRQEDXDYOZYLA-UHFFFAOYSA-N 0.000 claims description 9
- 230000003113 alkalizing effect Effects 0.000 claims description 9
- 239000002956 ash Substances 0.000 claims description 9
- 230000015556 catabolic process Effects 0.000 claims description 9
- 238000009833 condensation Methods 0.000 claims description 9
- 230000005494 condensation Effects 0.000 claims description 9
- 239000002994 raw material Substances 0.000 claims description 9
- 238000004040 coloring Methods 0.000 claims description 8
- ZXEKIIBDNHEJCQ-UHFFFAOYSA-N isobutanol Chemical compound CC(C)CO ZXEKIIBDNHEJCQ-UHFFFAOYSA-N 0.000 claims description 8
- 244000005700 microbiome Species 0.000 claims description 8
- 240000000111 Saccharum officinarum Species 0.000 claims description 7
- 235000007201 Saccharum officinarum Nutrition 0.000 claims description 7
- 238000009835 boiling Methods 0.000 claims description 7
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 claims description 6
- 235000002918 Fraxinus excelsior Nutrition 0.000 claims description 6
- 238000005345 coagulation Methods 0.000 claims description 6
- 230000015271 coagulation Effects 0.000 claims description 6
- 238000010908 decantation Methods 0.000 claims description 6
- 239000007791 liquid phase Substances 0.000 claims description 6
- 230000020477 pH reduction Effects 0.000 claims description 6
- AQIXEPGDORPWBJ-UHFFFAOYSA-N pentan-3-ol Chemical compound CCC(O)CC AQIXEPGDORPWBJ-UHFFFAOYSA-N 0.000 claims description 6
- 239000001963 growth medium Substances 0.000 claims description 5
- RXGUIWHIADMCFC-UHFFFAOYSA-N 2-Methylpropyl 2-methylpropionate Chemical compound CC(C)COC(=O)C(C)C RXGUIWHIADMCFC-UHFFFAOYSA-N 0.000 claims description 4
- FZXRXKLUIMKDEL-UHFFFAOYSA-N 2-Methylpropyl propanoate Chemical compound CCC(=O)OCC(C)C FZXRXKLUIMKDEL-UHFFFAOYSA-N 0.000 claims description 4
- 239000002253 acid Substances 0.000 claims description 4
- 239000006227 byproduct Substances 0.000 claims description 4
- 230000000694 effects Effects 0.000 claims description 4
- 239000008394 flocculating agent Substances 0.000 claims description 4
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 claims description 4
- HNAGHMKIPMKKBB-UHFFFAOYSA-N 1-benzylpyrrolidine-3-carboxamide Chemical compound C1C(C(=O)N)CCN1CC1=CC=CC=C1 HNAGHMKIPMKKBB-UHFFFAOYSA-N 0.000 claims description 3
- HFZLSTDPRQSZCQ-UHFFFAOYSA-N 1-pyrrolidin-3-ylpyrrolidine Chemical compound C1CCCN1C1CNCC1 HFZLSTDPRQSZCQ-UHFFFAOYSA-N 0.000 claims description 3
- 229940072049 amyl acetate Drugs 0.000 claims description 3
- PGMYKACGEOXYJE-UHFFFAOYSA-N anhydrous amyl acetate Natural products CCCCCOC(C)=O PGMYKACGEOXYJE-UHFFFAOYSA-N 0.000 claims description 3
- OBNCKNCVKJNDBV-UHFFFAOYSA-N butanoic acid ethyl ester Natural products CCCC(=O)OCC OBNCKNCVKJNDBV-UHFFFAOYSA-N 0.000 claims description 3
- AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 claims description 3
- 239000000920 calcium hydroxide Substances 0.000 claims description 3
- 229910001861 calcium hydroxide Inorganic materials 0.000 claims description 3
- MNWFXJYAOYHMED-UHFFFAOYSA-M heptanoate Chemical compound CCCCCCC([O-])=O MNWFXJYAOYHMED-UHFFFAOYSA-M 0.000 claims description 3
- 235000015927 pasta Nutrition 0.000 claims description 3
- 241000609240 Ambelania acida Species 0.000 claims description 2
- 239000010905 bagasse Substances 0.000 claims description 2
- 229920001577 copolymer Polymers 0.000 claims description 2
- HPXRVTGHNJAIIH-UHFFFAOYSA-N cyclohexanol Chemical compound OC1CCCCC1 HPXRVTGHNJAIIH-UHFFFAOYSA-N 0.000 claims description 2
- 238000005194 fractionation Methods 0.000 claims description 2
- GJRQTCIYDGXPES-UHFFFAOYSA-N iso-butyl acetate Natural products CC(C)COC(C)=O GJRQTCIYDGXPES-UHFFFAOYSA-N 0.000 claims description 2
- 229940035429 isobutyl alcohol Drugs 0.000 claims description 2
- FGKJLKRYENPLQH-UHFFFAOYSA-M isocaproate Chemical compound CC(C)CCC([O-])=O FGKJLKRYENPLQH-UHFFFAOYSA-M 0.000 claims description 2
- OQAGVSWESNCJJT-UHFFFAOYSA-N isovaleric acid methyl ester Natural products COC(=O)CC(C)C OQAGVSWESNCJJT-UHFFFAOYSA-N 0.000 claims description 2
- 239000007790 solid phase Substances 0.000 claims description 2
- SJZRECIVHVDYJC-UHFFFAOYSA-M 4-hydroxybutyrate Chemical compound OCCCC([O-])=O SJZRECIVHVDYJC-UHFFFAOYSA-M 0.000 claims 1
- 239000012736 aqueous medium Substances 0.000 claims 1
- 230000003570 biosynthesizing effect Effects 0.000 claims 1
- 238000005119 centrifugation Methods 0.000 claims 1
- 235000011007 phosphoric acid Nutrition 0.000 claims 1
- 150000003016 phosphoric acids Chemical class 0.000 claims 1
- 229920000520 poly(3-hydroxybutyrate-co-3-hydroxyvalerate) Polymers 0.000 claims 1
- 150000008163 sugars Chemical class 0.000 claims 1
- 238000003756 stirring Methods 0.000 abstract description 18
- 239000007787 solid Substances 0.000 description 87
- 210000004027 cell Anatomy 0.000 description 40
- 229920001222 biopolymer Polymers 0.000 description 28
- 239000000287 crude extract Substances 0.000 description 20
- 238000004519 manufacturing process Methods 0.000 description 19
- 239000000047 product Substances 0.000 description 18
- 238000004821 distillation Methods 0.000 description 16
- 229910052799 carbon Inorganic materials 0.000 description 15
- MLFHJEHSLIIPHL-UHFFFAOYSA-N isoamyl acetate Chemical compound CC(C)CCOC(C)=O MLFHJEHSLIIPHL-UHFFFAOYSA-N 0.000 description 15
- 239000000706 filtrate Substances 0.000 description 14
- 229920000980 poly(hydroxybutyrate-co-hydroxyvalerate) Polymers 0.000 description 14
- 238000012360 testing method Methods 0.000 description 12
- 241000252867 Cupriavidus metallidurans Species 0.000 description 11
- 230000014759 maintenance of location Effects 0.000 description 9
- 239000012466 permeate Substances 0.000 description 9
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 8
- 229910052753 mercury Inorganic materials 0.000 description 8
- 229920003023 plastic Polymers 0.000 description 8
- 239000004033 plastic Substances 0.000 description 8
- 238000010992 reflux Methods 0.000 description 8
- 241000588986 Alcaligenes Species 0.000 description 7
- 238000006731 degradation reaction Methods 0.000 description 7
- 229940117955 isoamyl acetate Drugs 0.000 description 7
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 6
- 241000196324 Embryophyta Species 0.000 description 6
- 239000000284 extract Substances 0.000 description 6
- 230000003834 intracellular effect Effects 0.000 description 6
- 239000002609 medium Substances 0.000 description 6
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 6
- 229920002792 polyhydroxyhexanoate Polymers 0.000 description 6
- 238000000746 purification Methods 0.000 description 6
- 229920002791 poly-4-hydroxybutyrate Polymers 0.000 description 5
- 238000012545 processing Methods 0.000 description 5
- 229920000704 biodegradable plastic Polymers 0.000 description 4
- 238000011161 development Methods 0.000 description 4
- 230000018109 developmental process Effects 0.000 description 4
- 238000013213 extrapolation Methods 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 230000035899 viability Effects 0.000 description 4
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 description 3
- 102000004190 Enzymes Human genes 0.000 description 3
- 108090000790 Enzymes Proteins 0.000 description 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 description 3
- 229920000331 Polyhydroxybutyrate Polymers 0.000 description 3
- 125000003342 alkenyl group Chemical group 0.000 description 3
- 125000000217 alkyl group Chemical group 0.000 description 3
- 230000033558 biomineral tissue development Effects 0.000 description 3
- 238000006243 chemical reaction Methods 0.000 description 3
- 230000007613 environmental effect Effects 0.000 description 3
- 230000036541 health Effects 0.000 description 3
- 238000004806 packaging method and process Methods 0.000 description 3
- 239000005015 poly(hydroxybutyrate) Substances 0.000 description 3
- CFXQEHVMCRXUSD-UHFFFAOYSA-N 1,2,3-Trichloropropane Chemical compound ClCC(Cl)CCl CFXQEHVMCRXUSD-UHFFFAOYSA-N 0.000 description 2
- FYGHSUNMUKGBRK-UHFFFAOYSA-N 1,2,3-trimethylbenzene Chemical compound CC1=CC=CC(C)=C1C FYGHSUNMUKGBRK-UHFFFAOYSA-N 0.000 description 2
- KWOLFJPFCHCOCG-UHFFFAOYSA-N Acetophenone Chemical compound CC(=O)C1=CC=CC=C1 KWOLFJPFCHCOCG-UHFFFAOYSA-N 0.000 description 2
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 2
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 2
- 239000003905 agrochemical Substances 0.000 description 2
- 230000001476 alcoholic effect Effects 0.000 description 2
- 150000001298 alcohols Chemical class 0.000 description 2
- -1 alkyl radical Chemical class 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 239000001506 calcium phosphate Substances 0.000 description 2
- 235000011010 calcium phosphates Nutrition 0.000 description 2
- 239000003990 capacitor Substances 0.000 description 2
- 239000000470 constituent Substances 0.000 description 2
- 238000013270 controlled release Methods 0.000 description 2
- 125000004122 cyclic group Chemical group 0.000 description 2
- 238000009826 distribution Methods 0.000 description 2
- 230000008030 elimination Effects 0.000 description 2
- 238000003379 elimination reaction Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000012452 mother liquor Substances 0.000 description 2
- 229920001013 poly(3-hydroxybutyrate-co-4-hydroxybutyrate) Polymers 0.000 description 2
- 229920005989 resin Polymers 0.000 description 2
- 239000011347 resin Substances 0.000 description 2
- 238000000935 solvent evaporation Methods 0.000 description 2
- 238000000638 solvent extraction Methods 0.000 description 2
- 230000003068 static effect Effects 0.000 description 2
- 229920001169 thermoplastic Polymers 0.000 description 2
- 239000004416 thermosoftening plastic Substances 0.000 description 2
- 231100000419 toxicity Toxicity 0.000 description 2
- 230000001988 toxicity Effects 0.000 description 2
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical class [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 2
- SCYULBFZEHDVBN-UHFFFAOYSA-N 1,1-Dichloroethane Chemical compound CC(Cl)Cl SCYULBFZEHDVBN-UHFFFAOYSA-N 0.000 description 1
- WSLDOOZREJYCGB-UHFFFAOYSA-N 1,2-Dichloroethane Chemical compound ClCCCl WSLDOOZREJYCGB-UHFFFAOYSA-N 0.000 description 1
- KNKRKFALVUDBJE-UHFFFAOYSA-N 1,2-dichloropropane Chemical compound CC(Cl)CCl KNKRKFALVUDBJE-UHFFFAOYSA-N 0.000 description 1
- ZSDQQJHSRVEGTJ-UHFFFAOYSA-N 2-(6-amino-1h-indol-3-yl)acetonitrile Chemical compound NC1=CC=C2C(CC#N)=CNC2=C1 ZSDQQJHSRVEGTJ-UHFFFAOYSA-N 0.000 description 1
- JTXMVXSTHSMVQF-UHFFFAOYSA-N 2-acetyloxyethyl acetate Chemical compound CC(=O)OCCOC(C)=O JTXMVXSTHSMVQF-UHFFFAOYSA-N 0.000 description 1
- 125000001340 2-chloroethyl group Chemical class [H]C([H])(Cl)C([H])([H])* 0.000 description 1
- 229910000497 Amalgam Inorganic materials 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 208000010392 Bone Fractures Diseases 0.000 description 1
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 1
- QKVZUZOLHJWGFQ-UHFFFAOYSA-N Cl.C(=C)(C)O Chemical compound Cl.C(=C)(C)O QKVZUZOLHJWGFQ-UHFFFAOYSA-N 0.000 description 1
- NTIZESTWPVYFNL-UHFFFAOYSA-N Methyl isobutyl ketone Chemical compound CC(C)CC(C)=O NTIZESTWPVYFNL-UHFFFAOYSA-N 0.000 description 1
- UIHCLUNTQKBZGK-UHFFFAOYSA-N Methyl isobutyl ketone Natural products CCC(C)C(C)=O UIHCLUNTQKBZGK-UHFFFAOYSA-N 0.000 description 1
- RJUFJBKOKNCXHH-UHFFFAOYSA-N Methyl propionate Chemical compound CCC(=O)OC RJUFJBKOKNCXHH-UHFFFAOYSA-N 0.000 description 1
- 238000010793 Steam injection (oil industry) Methods 0.000 description 1
- AAQDYYFAFXGBFZ-UHFFFAOYSA-N Tetrahydrofurfuryl acetate Chemical compound CC(=O)OCC1CCCO1 AAQDYYFAFXGBFZ-UHFFFAOYSA-N 0.000 description 1
- 239000001089 [(2R)-oxolan-2-yl]methanol Substances 0.000 description 1
- 239000001850 [(2R)-oxolan-2-yl]methyl acetate Substances 0.000 description 1
- 150000001242 acetic acid derivatives Chemical class 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- XYLMUPLGERFSHI-UHFFFAOYSA-N alpha-Methylstyrene Chemical compound CC(=C)C1=CC=CC=C1 XYLMUPLGERFSHI-UHFFFAOYSA-N 0.000 description 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 1
- 229920001448 anionic polyelectrolyte Polymers 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 238000006065 biodegradation reaction Methods 0.000 description 1
- 229910000389 calcium phosphate Inorganic materials 0.000 description 1
- 210000002421 cell wall Anatomy 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 238000004587 chromatography analysis Methods 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 238000002425 crystallisation Methods 0.000 description 1
- 230000008025 crystallization Effects 0.000 description 1
- 230000000593 degrading effect Effects 0.000 description 1
- 230000001627 detrimental effect Effects 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000000428 dust Substances 0.000 description 1
- 239000000975 dye Substances 0.000 description 1
- 238000005265 energy consumption Methods 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 239000003337 fertilizer Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 239000013505 freshwater Substances 0.000 description 1
- 239000000446 fuel Substances 0.000 description 1
- 238000012239 gene modification Methods 0.000 description 1
- 230000005017 genetic modification Effects 0.000 description 1
- 235000013617 genetically modified food Nutrition 0.000 description 1
- CATSNJVOTSVZJV-UHFFFAOYSA-N heptan-2-one Chemical compound CCCCCC(C)=O CATSNJVOTSVZJV-UHFFFAOYSA-N 0.000 description 1
- 239000004009 herbicide Substances 0.000 description 1
- 229930195733 hydrocarbon Natural products 0.000 description 1
- 150000002430 hydrocarbons Chemical class 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 230000002779 inactivation Effects 0.000 description 1
- 239000011261 inert gas Substances 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 239000002917 insecticide Substances 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 230000002427 irreversible effect Effects 0.000 description 1
- 238000012417 linear regression Methods 0.000 description 1
- 238000009630 liquid culture Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 229940017219 methyl propionate Drugs 0.000 description 1
- 239000002480 mineral oil Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 235000013379 molasses Nutrition 0.000 description 1
- HNBDRPTVWVGKBR-UHFFFAOYSA-N n-pentanoic acid methyl ester Natural products CCCCC(=O)OC HNBDRPTVWVGKBR-UHFFFAOYSA-N 0.000 description 1
- SNMVRZFUUCLYTO-UHFFFAOYSA-N n-propyl chloride Chemical class CCCCl SNMVRZFUUCLYTO-UHFFFAOYSA-N 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 239000005022 packaging material Substances 0.000 description 1
- 239000003348 petrochemical agent Substances 0.000 description 1
- 229920000071 poly(4-hydroxybutyrate) Polymers 0.000 description 1
- 229920000867 polyelectrolyte Polymers 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- RUOJZAUFBMNUDX-UHFFFAOYSA-N propylene carbonate Chemical compound CC1COC(=O)O1 RUOJZAUFBMNUDX-UHFFFAOYSA-N 0.000 description 1
- AOHJOMMDDJHIJH-UHFFFAOYSA-N propylenediamine Chemical compound CC(N)CN AOHJOMMDDJHIJH-UHFFFAOYSA-N 0.000 description 1
- 230000001172 regenerating effect Effects 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- BSYVTEYKTMYBMK-UHFFFAOYSA-N tetrahydrofurfuryl alcohol Chemical compound OCC1CCCO1 BSYVTEYKTMYBMK-UHFFFAOYSA-N 0.000 description 1
- 230000000930 thermomechanical effect Effects 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 238000012549 training Methods 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/88—Post-polymerisation treatment
- C08G63/90—Purification; Drying
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/88—Post-polymerisation treatment
- C08G63/89—Recovery of the polymer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/62—Carboxylic acid esters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/62—Carboxylic acid esters
- C12P7/625—Polyesters of hydroxy carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
- C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BR0306230 | 2003-11-28 | ||
| BR0306230 | 2003-11-28 | ||
| BRPI0405622-1A BRPI0405622B1 (pt) | 2004-11-19 | 2004-11-19 | PROCESSO PARA RECUPERAÇÃO DE POLIHIDROXIALCANOATOS (PHAs) DE BIOMASSA CELULAR |
| BR0405622 | 2004-11-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2319537T3 true ES2319537T3 (es) | 2009-05-08 |
Family
ID=34634788
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES04797154T Expired - Lifetime ES2319537T3 (es) | 2003-11-28 | 2004-11-25 | Proceso de recuperacion de polihidroxialcanoatos (phas) procedentes de una biomasa celular. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9045595B2 (enExample) |
| EP (1) | EP1687436B1 (enExample) |
| JP (1) | JP4709766B2 (enExample) |
| KR (1) | KR101130191B1 (enExample) |
| CN (1) | CN1886517B (enExample) |
| AU (1) | AU2004293501B2 (enExample) |
| CA (1) | CA2547689C (enExample) |
| DE (1) | DE602004018971D1 (enExample) |
| ES (1) | ES2319537T3 (enExample) |
| PT (1) | PT1687436E (enExample) |
| WO (1) | WO2005052175A2 (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10435297B2 (en) | 1999-06-16 | 2019-10-08 | Ardica Technologies, Inc. | Crystallization and stabilization in the synthesis of microcrystalline alpha alane |
| US10233079B2 (en) * | 1999-06-16 | 2019-03-19 | Ardica Technologies, Inc. | Heating methods for aluminum hydride production |
| EP1688450B2 (en) * | 2003-11-21 | 2012-08-01 | Kaneka Corporation | Process for producing polyhydroxyalkanoate crystal |
| TW200613560A (en) | 2004-06-29 | 2006-05-01 | Procter & Gamble | Solvent extraction of polyhydroxyalkanoates from biomass |
| AU2005285271B2 (en) | 2004-09-13 | 2010-09-09 | Metabolix, Inc. | Single solvent polymer extraction methods |
| BRPI0501844B1 (pt) * | 2005-03-04 | 2019-12-24 | Phb Ind S/A | processo para extração e recuperação de polihidroxialcanoatos (phas) a partir de uma biomassa celular bacteriana |
| EP1979394A1 (de) * | 2006-01-17 | 2008-10-15 | Basf Se | Verfahren zur gewinnung von polyhydroxyalkanoaten mit vermindertem gehalt an alkali- und erdalkalimetallen und erhöhter thermischer stabilität |
| CN100448911C (zh) * | 2006-03-06 | 2009-01-07 | 清华大学 | 一种提取微生物胞内聚羟基脂肪酸酯的方法 |
| BRPI0801845B1 (pt) * | 2008-06-09 | 2016-05-24 | Citrosuco S A Agroindústria | processo de obtenção de pha a partir de resíduo cítrico, pha obtido a partir de resíduo cítrico, composição polimérica contendo pha, artefato sólido contendo pha, artefato sólido contendo composição polimérica compreendendo pha, uso de resíduo cítrico para a obtenção de pha |
| BRPI0913675A2 (pt) | 2008-07-02 | 2015-11-24 | Basf Se | método para isolar poli-hidroxialcanoatos das células de produção |
| EP2366794B1 (en) | 2008-12-09 | 2017-02-22 | Kaneka Corporation | Method for producing poly-3-hydroxyalkanoate and agglomerate of poly-3-hydroxyalkanoate |
| JP5839855B2 (ja) * | 2011-06-29 | 2016-01-06 | 株式会社カネカ | ポリヒドロキシアルカノエートの製造方法 |
| ES2448823B1 (es) | 2012-08-14 | 2014-10-13 | Neol Biosolutions, S.A. | Producción de bioplásticos |
| EP2935463B1 (en) * | 2012-12-18 | 2017-02-08 | Veolia Water Solutions & Technologies Support | Method of producing polyhydroxyalkanoate compounded plastics having improved mechanical properties |
| US9290612B2 (en) * | 2013-03-13 | 2016-03-22 | Tepha, Inc. | Compositions and devices of poly-4-hydroxybutyrate |
| EP3065789B1 (en) | 2013-11-05 | 2018-10-24 | Tepha, Inc. | Compositions and devices of poly-4-hydroxybutyrate |
| CZ307015B6 (cs) | 2014-06-03 | 2017-11-15 | Nafigate Corporation, A.S. | Způsob izolace polyhydroxyalkanoátů z biomasy fermentované mikroorganismy produkujícími polyhydroxyalkanoáty a/nebo z biomasy obsahující alespoň jednu plodinu produkující polyhydroxyalkanoáty |
| WO2018070492A1 (ja) * | 2016-10-13 | 2018-04-19 | 株式会社カネカ | ポリヒドロキシアルカン酸の製造方法 |
| CN109504715A (zh) * | 2017-09-15 | 2019-03-22 | 北京蓝晶微生物科技有限公司 | 一种制备聚羟基脂肪酸酯（pha）的方法 |
| FR3080033B1 (fr) * | 2018-04-12 | 2020-07-17 | Societe D'exploitation De Produits Pour Les Industries Chimiques Seppic | Nouvelle composition a base d'acides polycafeoylquiniques, son utilisation en cosmetique et compositions cosmetiques en comprenant |
| CN113330068A (zh) * | 2018-08-24 | 2021-08-31 | 墨哈拉姆企业有限公司 | 可生物降解的聚合物组合物及其制备方法 |
| CN109517156A (zh) * | 2019-01-02 | 2019-03-26 | 清华大学 | 一种聚羟基脂肪酸酯的纯化方法 |
| EP4114203A1 (en) | 2020-03-05 | 2023-01-11 | VitaNav, Inc. | COMPOSITION OF (D)-ß-HYDROXYBUTYRIC ACID, (D)-ß-HYDROXYVALERIC ACID, AND (D)-1,3 BUTANEDIOL AS A NUTRITIONAL SUPPLEMENT AND THERAPEUTIC AGENT |
| CN111647151B (zh) * | 2020-06-10 | 2022-09-23 | 珠海麦得发生物科技股份有限公司 | 一种高效全自动二次纯化pha的工艺 |
| US11078328B1 (en) | 2020-10-30 | 2021-08-03 | Robert Whitehouse | Sequestered amorphous polyhydroxyalkanoate polymer (SAPP) material derived from cellular biomass and production thereof |
| US11104761B1 (en) | 2020-10-30 | 2021-08-31 | Robert Whitehouse | Sequestered amorphous polyhydroxyalkanoate polymer (SAPP) material derived from cellular biomass and production thereof |
| BR112023024355A2 (pt) * | 2021-06-28 | 2024-02-06 | Phb Ind S/A | Processo para produzir misturas opticamente ativas de (r)-3-hidroxibutirato e (r)-3-hidroxivalerato e método para tratar um indivíduo tendo uma doença metabólica |
| ES2936907B2 (es) * | 2021-09-14 | 2023-08-11 | Quim Tecnica Ecologica S L U | Metodo y equipos para la produccion de polihidroxialcanoatos y bioestimulante radicular a partir de residuos organicos |
| KR102548122B1 (ko) * | 2021-09-29 | 2023-06-28 | 한국에너지공과대학교 | 폴리하이드록시 알카노에이트의 제조방법, 이를 이용하여 제조된 폴리하이드록시 알카노에이트 및 폴리하이드록시 알카노에이트 제조용 건식 발효조 |
| KR102810479B1 (ko) * | 2022-08-04 | 2025-05-21 | 씨제이제일제당(주) | 색가 모니터링을 통한 정제 공정 제어 방법 및 시스템, 및 폴리하이드록시알카노에이트 수지의 제조 방법 |
| WO2025058384A1 (ko) * | 2023-09-12 | 2025-03-20 | 씨제이제일제당(주) | 폴리-4-하이드록시부티레이트를 포함하는 바이오매스의 회수 방법 |
| ES3014636B2 (es) * | 2023-10-18 | 2025-10-06 | Quim Tecnica Ecologica S L U | Metodo y equipos para la produccion de fertilizantes de uso agricola y bioplastico microbiano a partir de residuos organicos |
| KR20250055782A (ko) | 2023-10-18 | 2025-04-25 | 경희대학교 산학협력단 | 메탄자화균으로부터 폴리하이드록시알카노에이트를 추출 및 회수하는 방법 |
| AR131698A1 (es) | 2024-01-25 | 2025-04-23 | Ingenieria Metabolica S A | Proceso de producción y purificación económica de polihidroxibutirato (phb) de elevada pureza a partir de bacterias genéticamente modificadas |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3044942A (en) * | 1960-09-27 | 1962-07-17 | Grace W R & Co | Process for preparing poly-beta-hydroxybutyric acid |
| US3107172A (en) * | 1960-12-30 | 1963-10-15 | Grace W R & Co | Molded product containing poly-beta-hydroxybutyric acid and method of making |
| US3275610A (en) * | 1964-03-24 | 1966-09-27 | Mobil Oil Corp | Microbial synthesis of polymers |
| FR2446859A1 (fr) * | 1979-01-22 | 1980-08-14 | Solvay | Procede de separation de poly-b-hydroxybutyrates d'une biomasse |
| EP0015123B1 (en) | 1979-02-21 | 1982-12-22 | Imperial Chemical Industries Plc | A process for the extraction of poly-3-hydroxy-butyric acid from microbial cells |
| US4265770A (en) * | 1979-11-09 | 1981-05-05 | Amstar Corporation | Separation of suspended solids from phosphate tailings |
| GB8311677D0 (en) * | 1983-04-28 | 1983-06-02 | Ici Plc | Extraction process |
| FR2567149B1 (fr) * | 1984-07-06 | 1986-12-05 | Solvay | Procede pour l'extraction de poly-beta-hydroxybutyrates au moyen d'un solvant a partir d'une suspension aqueuse de micro-organismes |
| AT390068B (de) * | 1988-07-07 | 1990-03-12 | Danubia Petrochemie | Extraktionsmittel fuer poly-d(-)-3-hydroxybuttersaeure |
| CA1334430C (en) * | 1989-04-06 | 1995-02-14 | Claude Chavarie | Separation of poly-.beta.-hydroxyalkanoic acids from microbial biomass |
| AT395319B (de) * | 1990-10-05 | 1992-11-25 | Danubia Petrochem Polymere | Verfahren zur gewinnung eines polyhydroxyalkanoates aus dem zellmaterial eines mikroorganismus und polyhydroxyalkanoatflocken |
| ES2062955B1 (es) * | 1993-04-29 | 1995-06-16 | Repsol Quimica Sa | Procedimiento para la extraccion de polihidroxialcanoatos de bacterias halofilas que lo contienen. |
| BR9302312A (pt) * | 1993-06-30 | 1995-02-07 | Cooperativa De Produtores De C | Process de extração de biopolímeros |
| EP0763126B1 (en) | 1994-06-01 | 1999-07-21 | The Procter & Gamble Company | Process for recovering polyhydroxyalkanoates using centrifugal fractionation |
| NL9401037A (nl) * | 1994-06-23 | 1996-02-01 | Soonn Stichting Onderzoek En O | Werkwijze voor het bereiden van een biologisch afbreekbare polyhydroxyalkanoaat coating met behulp van een waterige dispersie van polyhydroxyalkanoaat. |
| US5942597A (en) * | 1995-08-21 | 1999-08-24 | The Procter & Gamble Company | Solvent extraction of polyhydroxyalkanoates from biomass |
| DE69621342T2 (de) | 1995-08-21 | 2003-01-23 | The Procter & Gamble Company, Cincinnati | Vereinfachte loesungsmittelextraktion von polyhydroxyalkanoaten aus biomasse durch verwendung eines marginalen nichtloesungsmittels fuer pha |
| US5821299A (en) * | 1996-02-16 | 1998-10-13 | The Proctor & Gamble Company | Solvent extraction of polyhydroxy-alkanoates from biomass facilitated by the use of marginal nonsolvent |
| DE19633475C2 (de) | 1996-08-20 | 2002-03-14 | Buna Sow Leuna Olefinverb Gmbh | Verfahren zur Gewinnung von Polyhydroxyalkanoaten und deren Verwendung |
| AU6971598A (en) * | 1997-04-15 | 1998-11-11 | Monsanto Company | Methods of pha extraction and recovery using non-halogenated solvents |
| US6087471A (en) * | 1997-04-15 | 2000-07-11 | Monsanto Company | High temperature PHA extraction using PHA-poor solvents |
| DE69942060D1 (de) * | 1998-04-08 | 2010-04-08 | Metabolix Inc | Verfahren für die trennung und reinigung von biopolymeren |
| WO1999064498A1 (en) * | 1998-06-09 | 1999-12-16 | Metabolix, Inc. | Methods and apparatus for the production of amorphous polymer suspensions |
| AU2001250800A1 (en) * | 2000-03-10 | 2001-09-24 | Metabolix, Inc. | Prevention of gelation of polyhydroxyalkanoate solutions using shear |
| JP4336509B2 (ja) | 2003-03-07 | 2009-09-30 | キヤノン株式会社 | 処理方法及びシステム |
| BRPI0501844B1 (pt) * | 2005-03-04 | 2019-12-24 | Phb Ind S/A | processo para extração e recuperação de polihidroxialcanoatos (phas) a partir de uma biomassa celular bacteriana |
-
2004
- 2004-11-25 WO PCT/BR2004/000237 patent/WO2005052175A2/en not_active Ceased
- 2004-11-25 KR KR1020067012268A patent/KR101130191B1/ko not_active Expired - Fee Related
- 2004-11-25 AU AU2004293501A patent/AU2004293501B2/en not_active Ceased
- 2004-11-25 CN CN2004800350921A patent/CN1886517B/zh not_active Expired - Fee Related
- 2004-11-25 ES ES04797154T patent/ES2319537T3/es not_active Expired - Lifetime
- 2004-11-25 DE DE602004018971T patent/DE602004018971D1/de not_active Expired - Lifetime
- 2004-11-25 US US10/596,077 patent/US9045595B2/en not_active Expired - Fee Related
- 2004-11-25 CA CA2547689A patent/CA2547689C/en not_active Expired - Fee Related
- 2004-11-25 PT PT04797154T patent/PT1687436E/pt unknown
- 2004-11-25 JP JP2006540109A patent/JP4709766B2/ja not_active Expired - Fee Related
- 2004-11-25 EP EP04797154A patent/EP1687436B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1687436B1 (en) | 2009-01-07 |
| AU2004293501B2 (en) | 2009-10-29 |
| CA2547689A1 (en) | 2005-06-09 |
| WO2005052175A2 (en) | 2005-06-09 |
| US20070161096A1 (en) | 2007-07-12 |
| DE602004018971D1 (de) | 2009-02-26 |
| KR20060134005A (ko) | 2006-12-27 |
| PT1687436E (pt) | 2009-03-05 |
| KR101130191B1 (ko) | 2012-03-29 |
| JP2007512007A (ja) | 2007-05-17 |
| CN1886517A (zh) | 2006-12-27 |
| JP4709766B2 (ja) | 2011-06-22 |
| US9045595B2 (en) | 2015-06-02 |
| CA2547689C (en) | 2014-10-21 |
| CN1886517B (zh) | 2013-07-17 |
| AU2004293501A1 (en) | 2005-06-09 |
| EP1687436A2 (en) | 2006-08-09 |
| WO2005052175A3 (en) | 2005-06-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2319537T3 (es) | Proceso de recuperacion de polihidroxialcanoatos (phas) procedentes de una biomasa celular. | |
| US6043063A (en) | Methods of PHA extraction and recovery using non-halogenated solvents | |
| US6087471A (en) | High temperature PHA extraction using PHA-poor solvents | |
| ES2384630T3 (es) | Procedimiento para el aislamiento de polihidroxialcanoatos (PHA) de c�lulas bacterianas mediante extracci�n en disolvente | |
| Tran et al. | An efficient and eco-friendly approach for the sustainable recovery and properties characterization of polyhydroxyalkanoates produced by methanotrophs | |
| MXPA00009754A (es) | Metodos para la separacion y purificacion de biopolimeros. | |
| WO2001068890A2 (en) | Method of extracting polyhydroxyalkanoate from a solution | |
| BRPI0405622B1 (pt) | PROCESSO PARA RECUPERAÇÃO DE POLIHIDROXIALCANOATOS (PHAs) DE BIOMASSA CELULAR | |
| MXPA06006073A (en) | Process for recovering polyhydroxialkanoates ("phas") from cellular biomass | |
| CZ2014384A3 (cs) | Způsob izolace polyhydroxyalkanoátů z biomasy fermentované mikroorganismy produkujícími polyhydroxyalkanoáty a/nebo z biomasy obsahující alespoň jednu plodinu produkující polyhydroxyalkanoáty | |
| LU et al. | VERFAHREN ZUR GEWINNUNG VON POLYHYDROXYALKANOLATEN (PHAS) AUS ZELLBIOMASSE PROCEDE DE RECUPERATION DE POLYHYDROXIALCANOATES (" PHAS") DANS UNE BIOMASSE CELLULAIRE | |
| ES3032519T3 (en) | Recovery of diols from a mixture | |
| TH83069A (th) | กรรมวิธีสำหรับสกัดและนำพอลิไฮดรอกซิแอลคานอเอท (PHAs) กลับคืนจากชีวมวลของเซลลูลาร์ | |
| TH62912B (th) | กรรมวิธีสำหรับสกัดและนำพอลิไฮดรอกซิแอลคานอเอท (PHAs) กลับคืนจากชีวมวลของเซลลูลาร์ | |
| BR102016015837A2 (pt) | Processos simplificados de recuperação de phas via extração química ou física complementados por separação química por diferença de polaridade ou tradicional | |
| LT et al. | Verfahren zur Isolierung von Polyhydroxyalkanoaten (PHAs) aus Bakterienzellen durch Lösungsmittelextraktion Procédé d’isolement de polyhydroxyalkanoates (PHAs) à partir de cellules bactériennes par l’extraction par solvant |