KR100910962B1 - Ｅｎｏ１―특이적인 인간항체 - Google Patents

Ｅｎｏ１―특이적인 인간항체 Download PDF

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Publication number
KR100910962B1
KR100910962B1 KR1020080092736A KR20080092736A KR100910962B1 KR 100910962 B1 KR100910962 B1 KR 100910962B1 KR 1020080092736 A KR1020080092736 A KR 1020080092736A KR 20080092736 A KR20080092736 A KR 20080092736A KR 100910962 B1 KR100910962 B1 KR 100910962B1
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KR
South Korea
Prior art keywords
cancer
ser
gly
eno1
human antibody
Prior art date
Application number
KR1020080092736A
Other languages
English (en)
Korean (ko)
Inventor
박영우
허광래
최소영
박지현
송은정
유정
손명호
김성섭
장명희
김동진
Original Assignee
한국생명공학연구원
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 한국생명공학연구원 filed Critical 한국생명공학연구원
Priority to KR1020080092736A priority Critical patent/KR100910962B1/ko
Priority to PCT/KR2008/006116 priority patent/WO2010032899A2/fr
Application granted granted Critical
Publication of KR100910962B1 publication Critical patent/KR100910962B1/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
KR1020080092736A 2008-09-22 2008-09-22 Ｅｎｏ１―특이적인 인간항체 KR100910962B1 (ko)

Priority Applications (2)

Application Number Priority Date Filing Date Title
KR1020080092736A KR100910962B1 (ko) 2008-09-22 2008-09-22 Ｅｎｏ１―특이적인 인간항체
PCT/KR2008/006116 WO2010032899A2 (fr) 2008-09-22 2008-10-16 Anticorps humain eno1-spécifique

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020080092736A KR100910962B1 (ko) 2008-09-22 2008-09-22 Ｅｎｏ１―특이적인 인간항체

Publications (1)

Publication Number Publication Date
KR100910962B1 true KR100910962B1 (ko) 2009-08-05

Family

ID=41209526

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020080092736A KR100910962B1 (ko) 2008-09-22 2008-09-22 Ｅｎｏ１―특이적인 인간항체

Country Status (2)

Country Link
KR (1) KR100910962B1 (fr)
WO (1) WO2010032899A2 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20140093901A (ko) * 2013-01-18 2014-07-29 서울대학교산학협력단 류마티스 관절염 진단용 바이오마커
TWI468176B (zh) * 2010-01-28 2015-01-11 Univ Taipei Medical 診斷及治療α－異烯醇酶（α－ｅｎｏｌａｓｅ）相關疾病之抗－α－異烯醇酶抗體

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8449881B2 (en) * 2010-01-28 2013-05-28 Taipei Medical University Anti-α-enolase I antibodies for diagnosis and treatment of α-enolase I-associated diseases
TWI572358B (zh) 2013-12-20 2017-03-01 財團法人生物技術開發中心 α－烯醇化酶特異性抗體及其使用在免疫疾病之方法
RU2656153C1 (ru) * 2013-12-20 2018-05-31 Девелопмент Сентер Фор Байотекнолоджи Антитела, специфичные к альфа-энолазе, и способы применения в противоопухолевой терапии
US9527922B2 (en) * 2014-12-31 2016-12-27 Development Center For Biotechnology Humanized alpha-enolase specific antibodies and methods of uses in cancer therapy
ES2823798T3 (es) * 2014-12-31 2021-05-10 Dev Ct Biotechnology Anticuerpos humanizados específicos de alfa-enolasa y procedimientos de usos en la terapia del cáncer
JP6786722B2 (ja) * 2016-08-05 2020-11-18 ワイ−バイオロジクス・インコーポレイテッド プログラム化された細胞死蛋白質（ｐｄ−１）に対する新規抗体及びその用途
KR20230026983A (ko) * 2020-05-11 2023-02-27 후닐라이프 바이오테크놀로지, 인코포레이트 알파-엔올라아제 항체들을 포함하는 약물 접합체 및 그의 이용

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070172487A1 (en) * 2005-12-30 2007-07-26 Neng-Yao Shih Alpha-enolase specific antibody and method of use

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58198758A (ja) * 1982-05-15 1983-11-18 Amano Pharmaceut Co Ltd ヒトエノラーゼの定量方法
US20070077583A1 (en) * 2005-09-21 2007-04-05 Aurelium Biopharma, Inc. Alpha enolase-directed diagnostics and therapeutics for cancer and chemotherapeutic drug resistance

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070172487A1 (en) * 2005-12-30 2007-07-26 Neng-Yao Shih Alpha-enolase specific antibody and method of use

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI468176B (zh) * 2010-01-28 2015-01-11 Univ Taipei Medical 診斷及治療α－異烯醇酶（α－ｅｎｏｌａｓｅ）相關疾病之抗－α－異烯醇酶抗體
KR20140093901A (ko) * 2013-01-18 2014-07-29 서울대학교산학협력단 류마티스 관절염 진단용 바이오마커
KR102438838B1 (ko) 2013-01-18 2022-09-02 서울대학교산학협력단 류마티스 관절염 진단용 바이오마커

Also Published As

Publication number Publication date
WO2010032899A2 (fr) 2010-03-25
WO2010032899A3 (fr) 2010-07-15

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