KR100851855B1 - 생약복합재 추출물을 함유하는 골길이 성장 촉진용 약학적조성물 - Google Patents
생약복합재 추출물을 함유하는 골길이 성장 촉진용 약학적조성물 Download PDFInfo
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Abstract
Description
속단 | 황기 | 산약 | 가시오가피 | 중국당귀 | ||
실시예 1 | 중량(g) | 2.6 | 10.5 | 47.5 | 9.9 | 26.2 |
중량부 | 2.6 | 10.5 | 47.5 | 9.9 | 26.2 | |
실시예 2 | 중량(g) | 10 | 20 | 40 | 10 | 20 |
중량부 | 1 | 2 | 4 | 1 | 2 | |
실시예 3 | 중량(g) | 10 | 10 | 50 | 20 | 20 |
중량부 | 1 | 1 | 5 | 2 | 2 | |
실시예 4 | 중량(g) | 10 | 20 | 40 | 20 | 20 |
중량부 | 1 | 2 | 4 | 2 | 2 | |
실시예 5 | 중량(g) | 3 | 10 | 50 | 10 | 20 |
중량부 | 3 | 10 | 50 | 10 | 20 |
실시예 1의 추출물 | 두충 추출물 | 홍삼 추출물 | ||
실시예 6 | 중량(㎎) | 100 | 10 | 10 |
중량부 | 1 | 0.1 | 0.1 | |
실시예 7 | 중량(㎎) | 100 | 10 | 0 |
중량부 | 1 | 0.1 | 0 | |
실시예 8 | 중량(㎎) | 100 | 0 | 10 |
중량부 | 1 | 0 | 0.1 |
속단 | 황기 | 산약 | 가시오가피 | 중국당귀 | ||
비교예 1 | 중량(g) | 50 | 0 | 0 | 0 | 0 |
중량부 | 1 | 0 | 0 | 0 | 0 | |
비교예 2 | 중량(g) | 0 | 50 | 0 | 0 | 0 |
중량부 | 0 | 1 | 0 | 0 | 0 | |
비교예 3 | 중량(g) | 0 | 0 | 50 | 0 | 0 |
중량부 | 0 | 0 | 1 | 0 | 0 | |
비교예 4 | 중량(g) | 0 | 0 | 0 | 50 | 0 |
중량부 | 0 | 0 | 0 | 1 | 0 | |
비교예 5 | 중량(g) | 0 | 0 | 0 | 0 | 50 |
중량부 | 0 | 0 | 0 | 0 | 1 |
구 분 | 골길이 성장(μm/day) | 골길이 성장률(%)1 ) |
음성 대조군(식염수) | 290.90 ± 6.23 | 100.00 ± 4.53 |
양성 대조군(성장호르몬) | 308.24 ± 12.15* | 105.96 ± 4.18* |
실시예 1 | 313.96 ± 12.85* | 107.93 ± 3.81* |
실시예 2 | 310.20 ± 13.26* | 106.63 ± 3.39* |
실시예 3 | 311.37 ± 10.08* | 107.03 ± 2.57* |
실시예 4 | 311.94 ± 8.24 | 107.23 ± 5.99 |
실시예 5 | 309.62 ± 6.23 | 106.43 ± 4.52 |
실시예 6 | 313.80 ± 10.12* | 107.87 ± 2.58* |
실시예 7 | 312.42 ± 7.81* | 107.39 ± 1.99* |
실시예 8 | 312.02 ± 5.62* | 107.26 ± 1.43* |
비교예 1 | 297.10 ± 11.54 | 102.82 ± 3.97 |
비교예 2 | 298.30 ± 30.25 | 102.54 ± 9.04 |
비교예 3 | 306.85 ± 14.16 | 105.48 ± 4.2 |
비교예 4 | 307.13 ± 13.08* | 105.58 ± 4.13* |
비교예 5 | 307.47 ± 14.68* | 105.69 ± 4.30* |
Claims (11)
- 속단, 황기, 산약, 가시오가피 및 당귀로 구성된 생약복합재 추출물을 유효성분으로 함유하는 골길이 성장 촉진용 약학적 조성물.
- 제 1항에 있어서, 추가적으로 두충 추출물 또는 홍삼 추출물이 첨가되는 것을 특징으로 하는 골길이 성장 촉진용 약학적 조성물.
- 제 1항에 있어서, 추출물은 속단 1 ~ 9 중량부, 황기 1 ~ 30 중량부, 산약 1 ~ 150 중량부, 가시오가피 1 ~ 30 중량부 및 당귀 1 ~ 60 중량부로 구성된 생약복합재로부터 추출되는 것을 특징으로 하는 골길이 성장 촉진용 약학적 조성물.
- 제 3항에 있어서, 추출물은 속단 1 ~ 6 중량부, 황기 1 ~ 20 중량부, 산약 1 ~ 100 중량부, 가시오가피 1 ~ 20 중량부 및 당귀 1 ~ 40 중량부로 구성된 생약복합재로부터 추출되는 것을 특징으로 하는 골길이 성장 촉진용 약학적 조성물.
- 제 4항에 있어서, 추출물은 속단 2.2 ~ 2.8 중량부, 황기 10.3 ~ 10.7 중량부, 산약 47.3 ~ 47.7 중량부, 가시오가피 9.7 ~ 10.1 중량부 및 당귀 26.0 ~ 26.4 중량부로 구성된 생약복합재로부터 추출되는 것을 특징으로 하는 골길이 성장 촉진용 약학적 조성물.
- 제 1항에 있어서, 생약복합재 추출물은 물, C1 내지 C4의 저급 알코올 또는 이들의 혼합물로 추출되는 것을 특징으로 하는 골길이 성장 촉진용 약학적 조성물.
- 삭제
- 제 6항에 있어서, 저급 알코올은 에탄올인 것을 특징으로 하는 골길이 성장촉진용 약학적 조성물.
- 제 6항에 있어서, 추출물은 실온에서 1 ~ 24 시간의 조건에서 추출되는 것을 특징으로 하는 골길이 성장 촉진용 약학적 조성물.
- 속단, 황기, 산약, 가시오가피 및 당귀로 구성된 생약복합재 추출물을 유효성분으로 함유하는 골길이 성장 촉진용 건강보조식품.
- 제 10항에 있어서, 건강보조식품은 분말, 과립, 정제, 캡슐, 캔디 또는 음료의 형태인 것을 특징으로 하는 골길이 성장 촉진용 건강보조식품.
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KR20160001392A (ko) | 2014-06-27 | 2016-01-06 | 경희대학교 산학협력단 | 한속단, 황기, 산약, 가시오가피 및 당귀의 복합 추출물을 유효성분으로 함유하는 골길이 성장 촉진용 조성물 |
KR20160111737A (ko) | 2015-03-17 | 2016-09-27 | 경희대학교 산학협력단 | 황기, 가시오갈피 및 속단의 복합 추출물을 유효성분으로 함유하는 골길이 성장 촉진용 조성물 |
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KR100436219B1 (ko) * | 1998-04-23 | 2005-09-02 | 주식회사 엘지생명과학 | 새로운성장호르몬분비촉진인자 |
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KR20160001392A (ko) | 2014-06-27 | 2016-01-06 | 경희대학교 산학협력단 | 한속단, 황기, 산약, 가시오가피 및 당귀의 복합 추출물을 유효성분으로 함유하는 골길이 성장 촉진용 조성물 |
KR20160111737A (ko) | 2015-03-17 | 2016-09-27 | 경희대학교 산학협력단 | 황기, 가시오갈피 및 속단의 복합 추출물을 유효성분으로 함유하는 골길이 성장 촉진용 조성물 |
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