KR100717897B1 - 면역 조절용 스테로이드, 특히16α-브로모에피안드로스테론의 헤미하이드레이트 - Google Patents

면역 조절용 스테로이드, 특히16α-브로모에피안드로스테론의 헤미하이드레이트 Download PDF

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KR100717897B1
KR100717897B1 KR1020017012156A KR20017012156A KR100717897B1 KR 100717897 B1 KR100717897 B1 KR 100717897B1 KR 1020017012156 A KR1020017012156 A KR 1020017012156A KR 20017012156 A KR20017012156 A KR 20017012156A KR 100717897 B1 KR100717897 B1 KR 100717897B1
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South Korea
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abandoned
composition
compound
payment
formula
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Korean (ko)
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KR20020003217A (ko
Inventor
알렘클라렌스나타니엘
프링키제임스마틴
디카르발로루이스다니엘도스앙조스
헤기윌리암
프렌더가스트패트릭티.
리딩크리스토퍼엘.
타딕콘다크루파커폴
베르논러셀닐
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홀리스-에덴 파마슈티칼즈, 인코포레이티드
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • AIDS & HIV (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1020017012156A 1999-03-23 2000-03-23 면역 조절용 스테로이드, 특히16α-브로모에피안드로스테론의 헤미하이드레이트 Expired - Fee Related KR100717897B1 (ko)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US12605699P 1999-03-23 1999-03-23
US60/126,056 1999-03-23
US14002899P 1999-06-16 1999-06-16
US60/140,028 1999-06-16
US41490599A 1999-10-08 1999-10-08
US09/414,905 1999-10-08
US16404899P 1999-11-08 1999-11-08
US60/164,048 1999-11-08

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020067027190A Division KR20070007394A (ko) 1999-03-23 2000-03-23 면역 조절용 스테로이드 및 이를 포함하는 약학 조성물

Publications (2)

Publication Number Publication Date
KR20020003217A KR20020003217A (ko) 2002-01-10
KR100717897B1 true KR100717897B1 (ko) 2007-05-14

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KR1020017012156A Expired - Fee Related KR100717897B1 (ko) 1999-03-23 2000-03-23 면역 조절용 스테로이드, 특히16α-브로모에피안드로스테론의 헤미하이드레이트
KR1020067027190A Ceased KR20070007394A (ko) 1999-03-23 2000-03-23 면역 조절용 스테로이드 및 이를 포함하는 약학 조성물

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020067027190A Ceased KR20070007394A (ko) 1999-03-23 2000-03-23 면역 조절용 스테로이드 및 이를 포함하는 약학 조성물

Country Status (22)

Country Link
EP (1) EP1163256B1 (enExample)
JP (1) JP2002540119A (enExample)
KR (2) KR100717897B1 (enExample)
CN (1) CN1243767C (enExample)
AP (1) AP2001002285A0 (enExample)
AT (1) ATE259825T1 (enExample)
AU (1) AU781997B2 (enExample)
BR (1) BR0009476A (enExample)
CA (1) CA2365081A1 (enExample)
CZ (1) CZ20013420A3 (enExample)
DE (1) DE60008353T2 (enExample)
DK (1) DK1163256T3 (enExample)
ES (1) ES2215631T3 (enExample)
HK (1) HK1046002B (enExample)
HU (1) HUP0203429A3 (enExample)
IL (1) IL144916A0 (enExample)
NO (2) NO320801B1 (enExample)
NZ (1) NZ513803A (enExample)
OA (1) OA11850A (enExample)
PT (1) PT1163256E (enExample)
RU (2) RU2295534C2 (enExample)
WO (1) WO2000056757A1 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070129282A1 (en) 1998-11-24 2007-06-07 Ahlem Clarence N Pharmaceutical treatments and compositions
US6667299B1 (en) 2000-03-16 2003-12-23 Hollis-Eden Pharmaceuticals, Inc. Pharmaceutical compositions and treatment methods
CA2669753C (en) 1999-09-30 2012-06-26 Hollis-Eden Pharmaceuticals, Inc. Therapeutic treatment of androgen receptor driven conditions
US7241753B2 (en) 2000-02-25 2007-07-10 Loria Roger M Method of treatment of prostate cancer
EP1372664A1 (en) * 2001-03-01 2004-01-02 Hollis-Eden Pharmaceuticals Inc. Use of certain steroids for treatment of blood cell deficiencies
FR2829697B1 (fr) * 2001-09-14 2004-03-19 Mayoly Spindler Lab Derives 7-hydroxyles et 7-cetoniques des hormones steroides 3 beta-hydroxylees pour le traitement des maladies inflammatoires ou fonctionnelles de l'intestin
KR20050057086A (ko) 2002-08-28 2005-06-16 홀리스-에덴 파마슈티칼즈, 인코포레이티드 치료적 처치 방법
GB0304927D0 (en) 2003-03-04 2003-04-09 Resolution Chemicals Ltd Process for the production of tibolone
KR20060125816A (ko) * 2003-12-26 2006-12-06 닛산 가가쿠 고교 가부시키 가이샤 호중구증다 억제제
MD4009C2 (ro) * 2008-07-15 2010-08-31 Институт Химии Академии Наук Молдовы Utilizarea 1-metil-4-(N-metilaminobutil-4)-β-carbolinei în calitate de remediu antituberculos
CN104072564B (zh) 2013-03-28 2016-08-17 广州市赛普特医药科技股份有限公司 2β,3α,5α-三羟基-雄甾-6-酮及其制备方法与用途
CN106565654B (zh) * 2016-10-14 2018-08-31 云南中烟工业有限责任公司 一种从白云参中提取的新型黄酮类化合物、其制备方法及其用途
BR112020021278A2 (pt) * 2018-06-01 2021-01-26 Société des Produits Nestlé S.A. butirato dietário
US10836788B2 (en) * 2019-02-05 2020-11-17 SD Chem, Inc. Aqueous suspension compositions, formulations, and water dispersible dry compositions comprising 16alpha-bromo-3beta-hydroxy-5alpha-androstan-17-ketone and hydrates, derivatives, and analogs thereof
CN119184282A (zh) * 2019-12-05 2024-12-27 雀巢产品有限公司 膳食丁酸盐
CN114907333B (zh) * 2022-05-11 2023-07-04 中国人民解放军军事科学院军事医学研究院 环丙甲酰胺衍生物及其制备方法和用途

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0289327A2 (en) * 1987-04-29 1988-11-02 Smithkline Beecham Corporation Steroid 5-alpha-reductase inhibitors
JPH0289327A (ja) * 1988-09-27 1990-03-29 Matsushita Electron Corp 銀ペースト塗布装置
EP0429187A1 (en) * 1989-10-26 1991-05-29 ELAN CORPORATION, Plc Enhanced bioavailability adsorbates
US5837269A (en) * 1989-09-25 1998-11-17 University Of Utah Research Foundation Vaccine compositions and method for enhancing an immune response

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH197784A (de) * 1934-05-25 1938-05-15 Schering Kahlbaum Ag Verfahren zu Darstellung von D5,6-trans-Androstendiol-3,17.
CA1314870C (en) * 1983-08-02 1993-03-23 Arthur G. Schwartz Steroids useful as anti-cancer, anti-obesity, anti-hyperglycemic, anti-autoimmune and anti-hypercholesterolemic agents
NL194728C (nl) * 1987-04-16 2003-01-07 Hollis Eden Pharmaceuticals Farmaceutisch preparaat geschikt voor de profylaxe of therapie van een retrovirale infectie of een complicatie of gevolg daarvan.

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0289327A2 (en) * 1987-04-29 1988-11-02 Smithkline Beecham Corporation Steroid 5-alpha-reductase inhibitors
JPH0289327A (ja) * 1988-09-27 1990-03-29 Matsushita Electron Corp 銀ペースト塗布装置
US5837269A (en) * 1989-09-25 1998-11-17 University Of Utah Research Foundation Vaccine compositions and method for enhancing an immune response
EP0429187A1 (en) * 1989-10-26 1991-05-29 ELAN CORPORATION, Plc Enhanced bioavailability adsorbates

Also Published As

Publication number Publication date
RU2295534C2 (ru) 2007-03-20
IL144916A0 (en) 2002-06-30
RU2417792C2 (ru) 2011-05-10
ATE259825T1 (de) 2004-03-15
EP1163256A1 (en) 2001-12-19
KR20070007394A (ko) 2007-01-15
EP1163256B1 (en) 2004-02-18
DE60008353D1 (de) 2004-03-25
CN1243767C (zh) 2006-03-01
CN1355809A (zh) 2002-06-26
CZ20013420A3 (cs) 2002-04-17
DK1163256T3 (da) 2004-06-28
OA11850A (en) 2006-03-06
HK1046002A1 (en) 2002-12-20
AP2001002285A0 (en) 2001-12-31
KR20020003217A (ko) 2002-01-10
HUP0203429A3 (en) 2004-07-28
HK1046002B (zh) 2006-10-20
ES2215631T3 (es) 2004-10-16
NO20056167L (no) 2001-11-21
CA2365081A1 (en) 2000-09-28
JP2002540119A (ja) 2002-11-26
HUP0203429A2 (hu) 2003-01-28
NO20014588L (no) 2001-11-21
AU781997B2 (en) 2005-06-23
RU2006133273A (ru) 2008-03-27
NO20014588D0 (no) 2001-09-21
BR0009476A (pt) 2002-02-19
DE60008353T2 (de) 2005-09-08
NO320801B1 (no) 2006-01-30
WO2000056757A1 (en) 2000-09-28
PT1163256E (pt) 2004-07-30
RU2001128881A (ru) 2003-09-27
NZ513803A (en) 2004-06-25
AU3919000A (en) 2000-10-09

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