KR100646753B1 - 시냅스 반응을 향상시키기 위한 아실벤즈옥사진 화합물 - Google Patents
시냅스 반응을 향상시키기 위한 아실벤즈옥사진 화합물 Download PDFInfo
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- KR100646753B1 KR100646753B1 KR1020007010679A KR20007010679A KR100646753B1 KR 100646753 B1 KR100646753 B1 KR 100646753B1 KR 1020007010679 A KR1020007010679 A KR 1020007010679A KR 20007010679 A KR20007010679 A KR 20007010679A KR 100646753 B1 KR100646753 B1 KR 100646753B1
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- South Korea
- Prior art keywords
- heteroarylalkyl
- arylalkyl
- compound
- fluoroalkyl
- alkyl
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/14—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9/054,916 | 1998-04-03 | ||
| US09/054,916 | 1998-04-03 | ||
| US09/054,916 US6124278A (en) | 1998-04-03 | 1998-04-03 | Acylbenzoxazines for enhancing synaptic response |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20010042192A KR20010042192A (ko) | 2001-05-25 |
| KR100646753B1 true KR100646753B1 (ko) | 2006-11-17 |
Family
ID=21994357
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020007010679A KR100646753B1 (ko) | 1998-04-03 | 1999-04-02 | 시냅스 반응을 향상시키기 위한 아실벤즈옥사진 화합물 |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US6124278A (xx) |
| EP (1) | EP1067935B1 (xx) |
| JP (1) | JP4574846B2 (xx) |
| KR (1) | KR100646753B1 (xx) |
| CN (1) | CN1186020C (xx) |
| AT (1) | ATE247472T1 (xx) |
| AU (1) | AU736376B2 (xx) |
| BR (1) | BR9909378A (xx) |
| CA (1) | CA2326764C (xx) |
| CZ (1) | CZ292931B6 (xx) |
| DE (1) | DE69910552T2 (xx) |
| DK (1) | DK1067935T3 (xx) |
| ES (1) | ES2207194T3 (xx) |
| HK (1) | HK1039060B (xx) |
| HU (1) | HUP0102321A3 (xx) |
| IL (1) | IL138284A0 (xx) |
| NO (1) | NO20004383L (xx) |
| NZ (1) | NZ506712A (xx) |
| PL (1) | PL195394B1 (xx) |
| PT (1) | PT1067935E (xx) |
| RU (1) | RU2246498C2 (xx) |
| TR (1) | TR200002849T2 (xx) |
| WO (1) | WO1999051240A1 (xx) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI232863B (en) | 2001-06-11 | 2005-05-21 | Akzo Nobel Nv | Benzoxazepine derivatives |
| MXPA03011562A (es) | 2001-06-14 | 2004-03-18 | Akzo Nobel Nv | Derivados de (pirido/tieno)-(f)-oxazepin-5-ona como moduladores positivos del receptor ampa. |
| SK2292004A3 (en) * | 2001-11-26 | 2004-09-08 | Cortex Pharma Inc | Carbonyl benzoxazine compounds for enhancement of glutamatergic synaptic responses |
| WO2009019032A2 (en) * | 2003-08-08 | 2009-02-12 | Dsm Ip Assets B.V. | Novel method for screening brain-active compounds |
| TW200800959A (en) | 2005-06-10 | 2008-01-01 | Wyeth Corp | Piperazine-piperidine antagonists and agonists of the 5-HT1a receptor |
| CL2008000119A1 (es) | 2007-01-16 | 2008-05-16 | Wyeth Corp | Compuestos derivados de pirazol, antagonistas del receptor nicotinico de acetilcolina; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como demencia senil, alzheimer y esquizofrenia. |
| JP5531011B2 (ja) * | 2008-06-06 | 2014-06-25 | サノフイ | ＴＡＦＩａの阻害剤としての大環状尿素およびスルファミド誘導体 |
| US20110218190A1 (en) * | 2008-11-10 | 2011-09-08 | The Regents Of The University Of California | Therapeutic uses of ampa receptor modulators for treatment of motor dysfunction |
| CA2915405A1 (en) | 2013-06-13 | 2014-12-18 | Veroscience Llc | Compositions and methods for treating metabolic disorders |
| CN108689876B (zh) * | 2018-06-28 | 2020-11-27 | 苏州东南药业股份有限公司 | 一种8-(2-羟基苯甲酰胺基)辛酸钠的制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0475908A1 (de) * | 1990-09-14 | 1992-03-18 | Ciba-Geigy Ag | Chromogene Lactamverbindungen und ihre Herstellung und Verwendung |
| PT651746E (pt) * | 1992-07-24 | 2002-09-30 | Univ California | Drogas que intensificam as respostas sinapticas mediadas por receptores de ampa |
| US5650409A (en) * | 1995-06-02 | 1997-07-22 | Cortex Pharmaceuticals, Inc. | Benzoyl piperidines/pyrrolidines for enhancing synaptic response |
| US5736543A (en) * | 1996-04-03 | 1998-04-07 | The Regents Of The University Of California | Benzoxazines for enhancing synaptic response |
| US5985871A (en) * | 1997-12-24 | 1999-11-16 | Cortex Pharmaceuticals, Inc. | Benzoxazine compounds for enhancing synaptic response |
-
1998
- 1998-04-03 US US09/054,916 patent/US6124278A/en not_active Expired - Lifetime
-
1999
- 1999-04-02 KR KR1020007010679A patent/KR100646753B1/ko not_active IP Right Cessation
- 1999-04-02 PT PT99915240T patent/PT1067935E/pt unknown
- 1999-04-02 CZ CZ20003614A patent/CZ292931B6/cs not_active IP Right Cessation
- 1999-04-02 CN CNB998046949A patent/CN1186020C/zh not_active Expired - Fee Related
- 1999-04-02 AT AT99915240T patent/ATE247472T1/de active
- 1999-04-02 RU RU2000127738/04A patent/RU2246498C2/ru not_active IP Right Cessation
- 1999-04-02 DK DK99915240T patent/DK1067935T3/da active
- 1999-04-02 CA CA2326764A patent/CA2326764C/en not_active Expired - Fee Related
- 1999-04-02 ES ES99915240T patent/ES2207194T3/es not_active Expired - Lifetime
- 1999-04-02 JP JP2000542011A patent/JP4574846B2/ja not_active Expired - Fee Related
- 1999-04-02 PL PL99345687A patent/PL195394B1/pl not_active IP Right Cessation
- 1999-04-02 WO PCT/US1999/007325 patent/WO1999051240A1/en not_active Application Discontinuation
- 1999-04-02 EP EP99915240A patent/EP1067935B1/en not_active Expired - Lifetime
- 1999-04-02 DE DE69910552T patent/DE69910552T2/de not_active Expired - Lifetime
- 1999-04-02 HU HU0102321A patent/HUP0102321A3/hu unknown
- 1999-04-02 TR TR2000/02849T patent/TR200002849T2/xx unknown
- 1999-04-02 NZ NZ506712A patent/NZ506712A/xx unknown
- 1999-04-02 AU AU33798/99A patent/AU736376B2/en not_active Ceased
- 1999-04-02 IL IL13828499A patent/IL138284A0/xx not_active IP Right Cessation
- 1999-04-02 BR BR9909378-2A patent/BR9909378A/pt not_active Application Discontinuation
-
2000
- 2000-09-04 NO NO20004383A patent/NO20004383L/no not_active Application Discontinuation
-
2002
- 2002-01-11 HK HK02100196.0A patent/HK1039060B/zh not_active IP Right Cessation
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