KR100537153B1 - 항바이러스약품감수성및내성그리고항바이러스약물의스크리닝을결정하는방법및조성물 - Google Patents

항바이러스약품감수성및내성그리고항바이러스약물의스크리닝을결정하는방법및조성물 Download PDF

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KR100537153B1
KR100537153B1 KR1019980705851A KR19980705851A KR100537153B1 KR 100537153 B1 KR100537153 B1 KR 100537153B1 KR 1019980705851 A KR1019980705851 A KR 1019980705851A KR 19980705851 A KR19980705851 A KR 19980705851A KR 100537153 B1 KR100537153 B1 KR 100537153B1
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hiv
hbv
virus
gene
resistance test
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KR19990082129A (ko
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대니얼 제이. 캐이폰
크리스토스 존 페트로포울로우스
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바이럴러직, 인코퍼레이티드
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • C—CHEMISTRY; METALLURGY
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/64—General methods for preparing the vector, for introducing it into the cell or for selecting the vector-containing host
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    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system
    • G01N33/505—Cells of the immune system involving T-cells
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    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5067—Liver cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Molecular Biology (AREA)
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  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
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  • Wood Science & Technology (AREA)
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  • Tropical Medicine & Parasitology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1019980705851A 1996-01-29 1997-01-29 항바이러스약품감수성및내성그리고항바이러스약물의스크리닝을결정하는방법및조성물 Expired - Fee Related KR100537153B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US59300996A 1996-01-29 1996-01-29
US08/593,009 1996-01-29
US8/593,009 1996-01-29

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KR19990082129A KR19990082129A (ko) 1999-11-15
KR100537153B1 true KR100537153B1 (ko) 2006-12-15

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KR1019980705851A Expired - Fee Related KR100537153B1 (ko) 1996-01-29 1997-01-29 항바이러스약품감수성및내성그리고항바이러스약물의스크리닝을결정하는방법및조성물

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EP (2) EP0852626B1 (enExample)
JP (1) JP4183749B2 (enExample)
KR (1) KR100537153B1 (enExample)
CN (1) CN1263867C (enExample)
AP (1) AP9801360A0 (enExample)
AT (1) ATE447621T1 (enExample)
AU (1) AU732255B2 (enExample)
CA (1) CA2216126C (enExample)
DE (2) DE69739645D1 (enExample)
EA (1) EA005426B1 (enExample)
ES (1) ES2175355T3 (enExample)
HU (1) HUP9900388A3 (enExample)
IL (1) IL125464A (enExample)
NO (1) NO983421L (enExample)
NZ (1) NZ331376A (enExample)
PL (1) PL328068A1 (enExample)
RO (1) RO118887B1 (enExample)
WO (1) WO1997027319A1 (enExample)

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AU1952897A (en) 1997-08-20
AP9801360A0 (en) 1998-12-31
EA005426B1 (ru) 2005-02-24
PL328068A1 (en) 1999-01-04
DE69711584D1 (de) 2002-05-08
JP4183749B2 (ja) 2008-11-19
DE69739645D1 (de) 2009-12-17
AU732255B2 (en) 2001-04-12
ES2175355T3 (es) 2002-11-16
JP2000503849A (ja) 2000-04-04
ATE447621T1 (de) 2009-11-15
IL125464A (en) 2007-12-03
NZ331376A (en) 2000-03-27
RO118887B1 (ro) 2003-12-30
HUP9900388A2 (hu) 1999-05-28
CA2216126A1 (en) 1997-07-31
WO1997027319A1 (en) 1997-07-31
CN1213407A (zh) 1999-04-07
EP0852626A1 (en) 1998-07-15
EP1170380A2 (en) 2002-01-09
CN1263867C (zh) 2006-07-12
DE69711584T2 (de) 2002-11-07
EP0852626A4 (en) 1999-08-25
HUP9900388A3 (en) 2005-03-29
IL125464A0 (en) 1999-03-12
NO983421D0 (no) 1998-07-24
EP1170380B1 (en) 2009-11-04
KR19990082129A (ko) 1999-11-15
EP0852626B1 (en) 2002-04-03
NO983421L (no) 1998-09-25
EP1170380A3 (en) 2003-05-02
CA2216126C (en) 2009-03-31
EA199800669A1 (ru) 1999-02-25

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