KR100536495B1 - 항알러지 및 항염증 활성을 갖는 다래 추출물을 함유하는식품 첨가제, 동물사료 첨가제 또는 화장료 조성물 - Google Patents
항알러지 및 항염증 활성을 갖는 다래 추출물을 함유하는식품 첨가제, 동물사료 첨가제 또는 화장료 조성물 Download PDFInfo
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/304—Foods, ingredients or supplements having a functional effect on health having a modulation effect on allergy and risk of allergy
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Mycology (AREA)
- Public Health (AREA)
- Botany (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Microbiology (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
- Fodder In General (AREA)
Abstract
Description
LPS 자극 | 처리 | IgE(IU/㎖) |
- | 배지 | 187.8 ±8.4 |
+ | 배지 | 392.9 ±3.4 |
+ | 다래 열수추출물 | 228.8 ±7.1 |
+ | 개다래 열수추출물 | 233.2 ±5.8 |
+ | 취다래 열수추출물 | 211.7 ±7.9 |
+ | 다래 줄기 열수추출물 | 241.5 ±5.8 |
+ | 다래 30% 에탄올 열수추출물 | 306.2 ±16.5 |
+ | 다래 50% 에탄올 열수추출물 | 201.9 ±27.6 |
+ | 다래 70% 에탄올 열수추출물 | 266.8 ±17.0 |
+ | 덱사메타손 | 203.6 ±30.9 |
LPS 자극 | 처리 | IgE (IU/㎖) |
- | 배지 | 117.4 ±7.6 |
+ | 배지 | 212.5 ±11.8 |
+ | 상기 실시예(1-1)의 다래 열수추출물 | 151.7 ±11.9 |
+ | 클로로포름 분획 | 206.7 ±15.6 |
+ | 에틸아세테이트 분획 | 123.3 ±8.1 |
+ | 물 분획 | 218.9 ±13.3 |
+ | 덱사메타손 | 138.9 ±2.1 |
LPS 자극 | 처리 | IgE (IU/㎖) |
- | 배지 | 379.7 ±13.2 |
+ | 배지 | 540.4 ±35.1 |
+ | 실시예 (2-2)의 에틸아세테이트 분획 | 298.1 ±9.7 |
+ | 실리카겔 분획 1 | 293.5 ±12.5 |
+ | 실리카겔 분획 2 | 307.6 ±24.1 |
+ | 실리카겔 분획 3 | 453.1 ±17.3 |
+ | 실리카겔 분획 4 | 396.9 ±26.8 |
+ | 덱사메타손 | 277.6 ±12.4 |
정상마우스 | 음용수 | 다래 열수추출물 | 덱사메타손 | |
IgE | 1.0 ±0.0 | 7.6 ±0.2 | 2.2 ±0.5 | 2.0 ±0.6 |
IgG1 | 1.0 ±0.0 | 5.1 ±0.1 | 3.3 ±0.3 | 3.1 ±0.3 |
IgG2a | 1.0 ±0.1 | 2.1 ±0.4 | 4.6 ±0.3 | 1.9 ±0.4 |
IgG2b | 1.0 ±0.0 | 1.4 ±0.1 | 1.5 ±0.2 | 1.2 ±0.1 |
정상마우스 | OVA 감작 마우스 | |||
음용수 | 다래 열수추출물 | 덱사메타손 | ||
IL-4 | 21.6 ±11.8 | 159.5 ±15.7 | 76.5 ±10.0 | 23.1 ±8.7 |
IL-5 | 0.5 ±0.8 | 2573.6 ±42.0 | 1638.3 ±33.3 | 884.1 ±80.7 |
IL-12 | 1626.0 ±58.5 | 906.2 ±66.0 | 1321.2 ±92.4 | 297.7 ±16.4 |
인터페론-감마 | 14.1 ±19.6 | 1016.0 ±25.6 | 1688.2 ±15.8 | 470.5 ±38.6 |
단위: pg/㎖ |
PHA 자극 | 처리 | IL-5 | IL-13 | IL-10 | 인터페론-감마 |
- | - | 92.2 ±6.4 | 0 ±0 | 0 ±0 | 53.3 ±30.2 |
+ | 배지 | 518.1 ±120.3 | 667.8 ±46.5 | 480.3 ±15.3 | 334.1 ±277.7 |
+ | 다래 열수추출물 | 248.5 ±62.0 | 355.7 ±93.1 | 570.2 ±56.3 | 1067 ±345.1 |
단위: pg/㎖ |
1 일 | 14 일 | 28 일 | 42 일 | |
알러지 환자 K | 950.8 IU/㎖ | 855.6 IU/㎖ | 679.1 IU/㎖ | 266.1 IU/㎖ |
알러지 환자 E | 278.3 IU/㎖ | 236.0 IU/㎖ | 189.2 IU/㎖ | 95.0 IU/㎖ |
처리 | 크로몰린(대조군) | 다래 열수추출물 |
저해율(%) | 52 ±13 | 44 ±10 |
처리 | 부종지수(㎎) | 저해율(%) |
대조군 | 7.2 ±1.1 | - |
다래 열수추출물 | 2.7 ±0.8 | 62.5 |
인도메타신 | 1.3 ±0.3 | 81.9 |
IgE | IgG1 | IgG2a | |
음용수 | 1572.9 ±77.4 | 242.2 ±14.2 | 177.5 ±17.2 |
다래 열수추출물 | 699.0 ±348.5 | 263.4 ±21.1 | 263.5 ±16.2 |
덱사메타손 | 130.0 ±55.3 | 247.3 ±10.8 | 148.0 ±14.8 |
단위: pg/㎖ |
IL-4 | IL-5 | IL-12 | 인터페론 감마 | |
음용수 | 151.9 ±2.2 | 778.3 ±34.1 | 1925.7 ±134.5 | 10407.5 ±130.8 |
다래 열수추출물 | 24.1 ±5.2 | 248.0 ±17.8 | 2346.2 ±98.4 | 15847.9 ±1693.1 |
덱사메타손 | 42.7 ±19.4 | 646.5 ±51.7 | 201.2 ±12.1 | 10096.4 ±192.4 |
단위: ng/㎖ |
Claims (30)
- 다래과실(Actinidia arguta)의 물, 에탄올 또는 이들의 혼합용매 가용 추출물을 유효성분으로 함유하는 알러지 질환의 예방 및 개선용 식품 첨가제.
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KR10-2003-0077911A KR100536495B1 (ko) | 2003-11-05 | 2003-11-05 | 항알러지 및 항염증 활성을 갖는 다래 추출물을 함유하는식품 첨가제, 동물사료 첨가제 또는 화장료 조성물 |
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KR10-2005-0099436A Division KR100533702B1 (ko) | 2005-10-21 | 2005-10-21 | 항알러지 및 항염증 활성을 갖는 다래 추출물을 함유하는동물사료 첨가제 |
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KR100880712B1 (ko) * | 2007-05-17 | 2009-02-02 | 건국대학교 산학협력단 | 탄닌 함유 목천료자 추출물을 유효성분으로 하는 소염 진통제 조성물 |
KR101026878B1 (ko) * | 2009-01-19 | 2011-04-06 | (주)애드바이오텍 | 사료 첨가제 |
KR20140065102A (ko) * | 2012-11-21 | 2014-05-29 | 주식회사 삼부메디칼 | 만병초, 비수리 및 다래나무 추출물을 포함하는 샴푸 조성물의 제조방법 |
US20220193163A1 (en) * | 2019-04-24 | 2022-06-23 | G&P Bioscience Co., Ltd. | Composition comprising actinidia polygama extract for alleviating skin damage or moisturizing skin |
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