KR100482946B1 - N-벤질-n-메틸아크릴아미드의 제조방법 - Google Patents

N-벤질-n-메틸아크릴아미드의 제조방법 Download PDF

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Publication number
KR100482946B1
KR100482946B1 KR10-2004-7013888A KR20047013888A KR100482946B1 KR 100482946 B1 KR100482946 B1 KR 100482946B1 KR 20047013888 A KR20047013888 A KR 20047013888A KR 100482946 B1 KR100482946 B1 KR 100482946B1
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KR
South Korea
Prior art keywords
lens
lenses
hydrogel
methylacrylamide
benzyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR10-2004-7013888A
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English (en)
Korean (ko)
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KR20040084954A (ko
Inventor
리자우슈가오
왕야딩
주스티븐큐.
Original Assignee
파마시아 아이오비젼 인코포레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication of KR20040084954A publication Critical patent/KR20040084954A/ko
Application granted granted Critical
Publication of KR100482946B1 publication Critical patent/KR100482946B1/ko
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/16Intraocular lenses
    • A61F2/1613Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A61F2/1616Pseudo-accommodative, e.g. multifocal or enabling monovision
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C233/09Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to carbon atoms of an acyclic unsaturated carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F20/00Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide or nitrile thereof
    • C08F20/02Monocarboxylic acids having less than ten carbon atoms, Derivatives thereof
    • C08F20/52Amides or imides
    • C08F20/54Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/16Intraocular lenses
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/924Material characteristic

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biomedical Technology (AREA)
  • Transplantation (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cardiology (AREA)
  • Materials For Medical Uses (AREA)
  • Eyeglasses (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Prostheses (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KR10-2004-7013888A 1996-03-25 1997-03-17 N-벤질-n-메틸아크릴아미드의 제조방법 Expired - Fee Related KR100482946B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/622,527 US5717049A (en) 1996-03-25 1996-03-25 High refractive index hydrogels prepared from polymers and copolymers of N-benzyl-N-methylacrylamide
US08/622,527 1996-03-25
PCT/IB1997/000348 WO1997035896A1 (en) 1996-03-25 1997-03-17 High refractive index hydrogels prepared from polymers and copolymers of n-benzyl-n-methylacrylamide

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR10-1998-0707560A Division KR100470247B1 (ko) 1996-03-25 1997-03-17 N-벤질-n-메틸아크릴아미드의중합체및공중합체로제조된고굴절율의하이드로겔

Publications (2)

Publication Number Publication Date
KR20040084954A KR20040084954A (ko) 2004-10-06
KR100482946B1 true KR100482946B1 (ko) 2005-04-15

Family

ID=24494514

Family Applications (1)

Application Number Title Priority Date Filing Date
KR10-2004-7013888A Expired - Fee Related KR100482946B1 (ko) 1996-03-25 1997-03-17 N-벤질-n-메틸아크릴아미드의 제조방법

Country Status (15)

Country Link
US (1) US5717049A (enExample)
EP (1) EP0889916B1 (enExample)
JP (1) JP2000507298A (enExample)
KR (1) KR100482946B1 (enExample)
CN (1) CN1103786C (enExample)
AT (1) ATE239758T1 (enExample)
AU (1) AU712171B2 (enExample)
BR (1) BR9708263A (enExample)
CA (1) CA2249991A1 (enExample)
DE (1) DE69721750T2 (enExample)
DK (1) DK0889916T3 (enExample)
ES (1) ES2200160T3 (enExample)
NZ (1) NZ331946A (enExample)
PT (1) PT889916E (enExample)
WO (1) WO1997035896A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6329485B1 (en) 1998-12-11 2001-12-11 Bausch & Lomb Incorporated High refractive index hydrogel compositions for ophthalmic implants
AUPP939299A0 (en) 1999-03-23 1999-04-15 University Of Melbourne, The Polymer gels and methods for their preparation
AU2002356295A1 (en) * 2001-12-19 2003-06-30 First Water Limited Hydrogel compositions comprising an acryloyl morpholine polymer
US20030223954A1 (en) * 2002-05-31 2003-12-04 Ruscio Dominic V. Polymeric materials for use as photoablatable inlays
US6737448B2 (en) * 2002-06-03 2004-05-18 Staar Surgical Company High refractive index, optically clear and soft hydrophobic acrylamide copolymers
JP4349776B2 (ja) * 2002-06-04 2009-10-21 株式会社ニデック 眼内レンズの製造方法
DE102006028507A1 (de) * 2006-06-21 2007-12-27 *Acri.Tec AG Gesellschaft für ophthalmologische Produkte Ophthalmologische Zusammensetzung und ihre Verwendung
ES2365290T3 (es) * 2007-07-25 2011-09-28 Alcon, Inc. Materiales para dispositivo oftálmico de alto índice de refracción.
DE102011112778A1 (de) * 2011-09-09 2013-03-14 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Die Primärwaschkraft verbessernde polymere Wirkstoffe
CN104558403B (zh) * 2013-10-28 2016-09-07 中国石油化工股份有限公司 交联渐变溶胀型聚合物微球及其制备方法
CN103655003A (zh) * 2013-12-13 2014-03-26 无锡合众信息科技有限公司 一种可折叠后房室固定型人工晶体及其制备方法
US12127934B2 (en) 2014-09-09 2024-10-29 Staar Surgical Company Method of Providing Modified Monovision to a Subject with a First Lens and a Second Lens
CN111265331B (zh) 2014-09-09 2022-09-09 斯塔尔外科有限公司 具有扩展的景深和增强的远距视力的眼科植入物
JP6924696B2 (ja) * 2014-10-17 2021-08-25 キー メディカル テクノロジーズ インコーポレイテッド 眼適用のためのポリマーおよび方法
AU2017229594B2 (en) 2016-03-09 2022-06-16 Staar Surgical Company Ophthalmic implants with extended depth of field and enhanced distance visual acuity
EP3837571B1 (en) 2018-08-17 2023-08-02 Staar Surgical Company Polymeric composition exhibiting nanogradient of refractive index
CA3234381A1 (en) 2021-10-04 2023-04-13 Staar Surgical Company Ophthalmic implants for correcting vision with a tunable optic, and methods of manufacture and use
DE102022125341B3 (de) * 2022-09-30 2024-01-04 Carl Zeiss Meditec Ag Ophthalmologische Zusammensetzung mit mehreren Comonomergruppen und ophthalmologische Linse

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2541930A (en) * 1946-11-16 1951-02-13 Geigy Ag J R Amides of monocarboxylic acids having acaricidal and disinfecting properties
GB855741A (en) * 1958-08-30 1960-12-07 British Nylon Spinners Ltd Improvements in or relating to polyacrylamide derivatives
CH476689A (de) * 1965-04-01 1969-08-15 Ciba Geigy Verfahren zur Herstellung neuer polymerisierbarer N-Aryl-methylcarbonsäureamide
US3716467A (en) * 1968-07-05 1973-02-13 Agency Ind Science Techn Process for the radiation insolubilization of n-(vinyl) phenylacrylamide
US4337332A (en) * 1981-04-09 1982-06-29 Minnesota Mining And Manufacturing Company Latently curable organosilicone compositions
DE4023578A1 (de) * 1990-07-25 1992-01-30 Chemie Linz Deutschland Copolymere von hydroxyethyl(meth)acrylat und n-substituierten (meth)acrylamiden
US5480950A (en) * 1992-09-28 1996-01-02 Kabi Pharmacia Ophthalmics, Inc. High refractive index hydrogels and uses thereof
US5439950A (en) * 1994-06-27 1995-08-08 Kabi Pharmacia Ophthalmics, Inc. Water miscible non-hydrolyzable cross-linkers and high refractive index hydrogels prepared therewith
DE4423303C2 (de) * 1994-07-02 2000-05-31 Woehlk Contact Linsen Gmbh Hydrophile, vernetzte Copolymere auf der Basis von N-Vinylformamid, Verfahren zu ihrer Herstellung und ihre Verwendung

Also Published As

Publication number Publication date
KR20040084954A (ko) 2004-10-06
WO1997035896A1 (en) 1997-10-02
DE69721750T2 (de) 2003-11-13
CA2249991A1 (en) 1997-10-02
BR9708263A (pt) 2000-01-04
EP0889916B1 (en) 2003-05-07
AU712171B2 (en) 1999-10-28
EP0889916A4 (en) 2000-06-28
DE69721750D1 (de) 2003-06-12
NZ331946A (en) 2000-03-27
CN1219179A (zh) 1999-06-09
US5717049A (en) 1998-02-10
JP2000507298A (ja) 2000-06-13
PT889916E (pt) 2003-08-29
ES2200160T3 (es) 2004-03-01
DK0889916T3 (da) 2003-07-28
ATE239758T1 (de) 2003-05-15
CN1103786C (zh) 2003-03-26
AU2040497A (en) 1997-10-17
EP0889916A1 (en) 1999-01-13

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