KR100481254B1 - 미르타자핀과하나이상의선택적인세로토닌재흡수저해제를포함하는약학조성물 - Google Patents

미르타자핀과하나이상의선택적인세로토닌재흡수저해제를포함하는약학조성물 Download PDF

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KR100481254B1
KR100481254B1 KR1019970025307A KR19970025307A KR100481254B1 KR 100481254 B1 KR100481254 B1 KR 100481254B1 KR 1019970025307 A KR1019970025307 A KR 1019970025307A KR 19970025307 A KR19970025307 A KR 19970025307A KR 100481254 B1 KR100481254 B1 KR 100481254B1
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South Korea
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mirtazapine
ssri
pharmaceutically acceptable
serotonin reuptake
selective serotonin
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Expired - Fee Related
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KR1019970025307A
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English (en)
Korean (ko)
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KR980000447A (ko
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요한네스 니콜슨 빅토르
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악조 노벨 엔.브이.
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Application filed by 악조 노벨 엔.브이. filed Critical 악조 노벨 엔.브이.
Publication of KR980000447A publication Critical patent/KR980000447A/ko
Application granted granted Critical
Publication of KR100481254B1 publication Critical patent/KR100481254B1/ko
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1019970025307A 1996-06-19 1997-06-18 미르타자핀과하나이상의선택적인세로토닌재흡수저해제를포함하는약학조성물 Expired - Fee Related KR100481254B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP96201703.4 1996-06-19
EP96201703 1996-06-19

Publications (2)

Publication Number Publication Date
KR980000447A KR980000447A (ko) 1998-03-30
KR100481254B1 true KR100481254B1 (ko) 2005-09-12

Family

ID=8224094

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019970025307A Expired - Fee Related KR100481254B1 (ko) 1996-06-19 1997-06-18 미르타자핀과하나이상의선택적인세로토닌재흡수저해제를포함하는약학조성물

Country Status (24)

Country Link
US (1) US5977099A (https=)
JP (2) JP4925074B2 (https=)
KR (1) KR100481254B1 (https=)
CN (1) CN1132581C (https=)
AR (1) AR007609A1 (https=)
AT (1) ATE213159T1 (https=)
AU (1) AU727851B2 (https=)
BR (1) BR9703624A (https=)
CA (1) CA2208199C (https=)
CZ (1) CZ290691B6 (https=)
DE (1) DE69710390T2 (https=)
DK (1) DK0813873T3 (https=)
ES (1) ES2172744T3 (https=)
HU (1) HU225534B1 (https=)
ID (1) ID17051A (https=)
IL (1) IL121076A (https=)
NO (1) NO313177B1 (https=)
NZ (1) NZ328113A (https=)
PL (1) PL188520B1 (https=)
PT (1) PT813873E (https=)
RU (1) RU2181287C2 (https=)
SG (1) SG60073A1 (https=)
TR (1) TR199700522A3 (https=)
ZA (1) ZA975335B (https=)

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US6727283B2 (en) 1998-10-13 2004-04-27 Pfizer Inc. Sertraline oral concentrate
US6575147B2 (en) * 1999-02-25 2003-06-10 Go-Tec Internal combustion system adapted for use of a dual fuel composition including acetylene
AU781221B2 (en) * 1999-04-19 2005-05-12 Teva Pharmaceutical Industries Ltd. Novel synthesis and crystallization of piperazine ring-containing compounds
US6545149B2 (en) 1999-04-19 2003-04-08 Teva Pharmaceutical Industries Ltd. Synthesis and crystallization of piperazine ring-containing compounds
US6759437B2 (en) * 1999-10-04 2004-07-06 Martin C. Hinz Comprehensive pharmacologic therapy for treatment of obesity including cysteine
US6403657B1 (en) * 1999-10-04 2002-06-11 Martin C. Hinz Comprehensive pharmacologic therapy for treatment of obesity
TWI256309B (en) * 1999-10-13 2006-06-11 Akzo Nobel Nv New formulation of mirtazapine
AU780817B2 (en) * 2000-01-19 2005-04-21 Akzo Nobel N.V. Drug combination for the treatment of depression and related disorders comprising mirtazapine and gepirone
BR0108261A (pt) * 2000-02-11 2003-03-05 Akzo Nobel Nv Uso de mirtazapina, método de tratamento de um distúrbio do sono em um indivìduo, e, kit para paciente para o tratamento de distúrbios do sono
AU2002212888A1 (en) * 2000-11-01 2002-05-15 Respiratorius Ab Composition comprising: serotonin receptor antagonists (5ht-2, 5ht-3) and agonist (5ht-4)
DE60224078T2 (de) * 2001-02-12 2008-12-04 N.V. Organon Verwendung von Mirtazapin zur Verbesserung der Behandlung von Menschen mit starken Depressionen, welche Träger des Gens für Apolipoprotein E4 sind.
US20030105082A1 (en) * 2001-12-03 2003-06-05 Murphy Greer Marechal Methods for improving the therapeutic response of humans having major depression and carrying the gene for apolipoprotein E4
US6399310B1 (en) 2001-02-12 2002-06-04 Akzo Nobel N.V. Methods for improving the therapeutic response of humans having major depression and carrying the gene for apolipoprotein E4
US20090311795A1 (en) * 2002-03-21 2009-12-17 Hinz Martin C Bilateral control of functions traditionally regulated by only serotonin or only dopamine
US20070293571A1 (en) * 2006-06-08 2007-12-20 Hinz Martin C Adminstration of dopa precursors with sources of dopa to effectuate optimal catecholamine neurotransmitter outcomes
EP1490073A4 (en) * 2002-03-21 2006-02-01 Martin C Hinz SEGMENT OPTIMIZATION TECHNOLOGY FOR THE SEROTONIN AND CATECHOLAMINE SYSTEM
AU2003274608A1 (en) * 2002-11-07 2004-06-07 Sunil Sadanand Nadkarni Process for preparation of polymorphic form of sertraline hydrochloride
KR100842694B1 (ko) * 2002-12-27 2008-07-01 오쓰까 세이야꾸 가부시키가이샤 기분 장애 치료용 카르보스티릴 유도체 및 세로토닌 재흡수억제제
AR042806A1 (es) * 2002-12-27 2005-07-06 Otsuka Pharma Co Ltd Combinacion de derivados de carboestirilo e inhibidores de la reabsorcion de serotonina para el tratamiento de trastornos del animo
MXPA05008943A (es) * 2003-02-21 2005-11-08 C Hinz Martin Tecnologia de optimizacion del segmento de sistema de serotonina y catecolamina.
TW200502222A (en) * 2003-04-02 2005-01-16 Novartis Ag Use of 10-hydroxy-10,11-dihydrocarbamazepine derivatives for the treatment of affective disorders
HUE034290T2 (en) 2003-04-29 2018-02-28 Orexigen Therapeutics Inc Preparations containing opioid antagonist and bupropion to affect weight loss
US20050234093A1 (en) * 2003-06-25 2005-10-20 H. Lundbeck A/S Treatment of depression and other affective disorders
US7838029B1 (en) * 2003-07-31 2010-11-23 Watson Laboratories, Inc. Mirtazapine solid dosage forms
US7390503B1 (en) 2003-08-22 2008-06-24 Barr Laboratories, Inc. Ondansetron orally disintegrating tablets
WO2005023767A2 (en) 2003-09-10 2005-03-17 Brentwood Equities Ltd. Diastereomers of 4-aryloxy-3-hydroxypiperidines
US7713959B2 (en) * 2004-01-13 2010-05-11 Duke University Compositions of an anticonvulsant and mirtazapine to prevent weight gain
TW200538100A (en) * 2004-04-21 2005-12-01 Akzo Nobel Nv Mirtazapine salts
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CA2630624C (en) 2005-11-22 2013-08-06 Orexigen Therapeutics, Inc. Compositions and methods for increasing insulin sensitivity
US8916195B2 (en) 2006-06-05 2014-12-23 Orexigen Therapeutics, Inc. Sustained release formulation of naltrexone
KR20170077291A (ko) 2006-11-09 2017-07-05 오렉시젠 세러퓨틱스 인크. 단위 용량 팩키지
TWI609702B (zh) 2006-11-09 2018-01-01 歐瑞根治療有限公司 層狀醫藥調配物
EP2167096A4 (en) * 2007-06-13 2010-07-14 Cypress Bioscience Inc IMPROVING TOLERANCE TO MIRTAZAPINE AND A SECOND ACTIVE INGREDIENT BY THE COMBINED USE OF THEM
CN101332193B (zh) * 2007-06-29 2012-12-12 杭州民生药业有限公司 一种马来酸氟伏沙明药物组合物的制备方法
JP2011521973A (ja) 2008-05-30 2011-07-28 オレキシジェン・セラピューティクス・インコーポレーテッド 内臓脂肪の状態を処置するための方法
KR101360698B1 (ko) 2009-06-09 2014-02-07 스미도모쥬기가이고교 가부시키가이샤 하이브리드식 쇼벨 및 그 제어방법
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Also Published As

Publication number Publication date
CZ290691B6 (cs) 2002-09-11
ID17051A (id) 1997-12-04
DE69710390T2 (de) 2002-08-14
CN1173330A (zh) 1998-02-18
HUP9701068A3 (en) 2000-07-28
JP2009137970A (ja) 2009-06-25
DK0813873T3 (da) 2002-05-27
CA2208199C (en) 2006-10-24
NO313177B1 (no) 2002-08-26
DE69710390D1 (de) 2002-03-21
TR199700522A2 (xx) 1998-01-21
IL121076A (en) 2000-10-31
BR9703624A (pt) 1998-09-01
ATE213159T1 (de) 2002-02-15
HK1006081A1 (en) 1999-02-12
CZ187097A3 (cs) 1998-01-14
TR199700522A3 (tr) 1998-01-21
PT813873E (pt) 2002-06-28
PL320628A1 (en) 1997-12-22
NZ328113A (en) 1999-09-29
HU9701068D0 (en) 1997-08-28
CA2208199A1 (en) 1997-12-19
HU225534B1 (en) 2007-02-28
IL121076A0 (en) 1997-11-20
NO972816L (no) 1997-12-22
ZA975335B (en) 1998-01-26
CN1132581C (zh) 2003-12-31
ES2172744T3 (es) 2002-10-01
JPH1067663A (ja) 1998-03-10
RU2181287C2 (ru) 2002-04-20
MX9704579A (es) 1998-07-31
HUP9701068A2 (hu) 1998-08-28
AU2612997A (en) 1998-01-08
KR980000447A (ko) 1998-03-30
AU727851B2 (en) 2001-01-04
JP4925074B2 (ja) 2012-04-25
PL188520B1 (pl) 2005-02-28
US5977099A (en) 1999-11-02
AR007609A1 (es) 1999-11-10
SG60073A1 (en) 1999-02-22
NO972816D0 (no) 1997-06-18

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