KR100481254B1 - 미르타자핀과하나이상의선택적인세로토닌재흡수저해제를포함하는약학조성물 - Google Patents

미르타자핀과하나이상의선택적인세로토닌재흡수저해제를포함하는약학조성물 Download PDF

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Publication number
KR100481254B1
KR100481254B1 KR1019970025307A KR19970025307A KR100481254B1 KR 100481254 B1 KR100481254 B1 KR 100481254B1 KR 1019970025307 A KR1019970025307 A KR 1019970025307A KR 19970025307 A KR19970025307 A KR 19970025307A KR 100481254 B1 KR100481254 B1 KR 100481254B1
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South Korea
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mirtazapine
ssri
pharmaceutically acceptable
serotonin reuptake
selective serotonin
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Expired - Fee Related
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KR1019970025307A
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English (en)
Korean (ko)
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KR980000447A (ko
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요한네스 니콜슨 빅토르
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악조 노벨 엔.브이.
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Application filed by 악조 노벨 엔.브이. filed Critical 악조 노벨 엔.브이.
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Publication of KR100481254B1 publication Critical patent/KR100481254B1/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1019970025307A 1996-06-19 1997-06-18 미르타자핀과하나이상의선택적인세로토닌재흡수저해제를포함하는약학조성물 Expired - Fee Related KR100481254B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP96201703 1996-06-19
EP96201703.4 1996-06-19

Publications (2)

Publication Number Publication Date
KR980000447A KR980000447A (ko) 1998-03-30
KR100481254B1 true KR100481254B1 (ko) 2005-09-12

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ID=8224094

Family Applications (1)

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KR1019970025307A Expired - Fee Related KR100481254B1 (ko) 1996-06-19 1997-06-18 미르타자핀과하나이상의선택적인세로토닌재흡수저해제를포함하는약학조성물

Country Status (24)

Country Link
US (1) US5977099A (https=)
JP (2) JP4925074B2 (https=)
KR (1) KR100481254B1 (https=)
CN (1) CN1132581C (https=)
AR (1) AR007609A1 (https=)
AT (1) ATE213159T1 (https=)
AU (1) AU727851B2 (https=)
BR (1) BR9703624A (https=)
CA (1) CA2208199C (https=)
CZ (1) CZ290691B6 (https=)
DE (1) DE69710390T2 (https=)
DK (1) DK0813873T3 (https=)
ES (1) ES2172744T3 (https=)
HU (1) HU225534B1 (https=)
ID (1) ID17051A (https=)
IL (1) IL121076A (https=)
NO (1) NO313177B1 (https=)
NZ (1) NZ328113A (https=)
PL (1) PL188520B1 (https=)
PT (1) PT813873E (https=)
RU (1) RU2181287C2 (https=)
SG (1) SG60073A1 (https=)
TR (1) TR199700522A3 (https=)
ZA (1) ZA975335B (https=)

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US6545149B2 (en) 1999-04-19 2003-04-08 Teva Pharmaceutical Industries Ltd. Synthesis and crystallization of piperazine ring-containing compounds
AU781221B2 (en) * 1999-04-19 2005-05-12 Teva Pharmaceutical Industries Ltd. Novel synthesis and crystallization of piperazine ring-containing compounds
US6403657B1 (en) * 1999-10-04 2002-06-11 Martin C. Hinz Comprehensive pharmacologic therapy for treatment of obesity
US6759437B2 (en) * 1999-10-04 2004-07-06 Martin C. Hinz Comprehensive pharmacologic therapy for treatment of obesity including cysteine
TWI256309B (en) * 1999-10-13 2006-06-11 Akzo Nobel Nv New formulation of mirtazapine
RU2268725C2 (ru) * 2000-01-19 2006-01-27 Акцо Нобель Н.В. Комбинация лекарственных препаратов, включающая миртазапин, для лечения депрессии и связанных расстройств
CA2396209C (en) * 2000-02-11 2009-09-01 Akzo Nobel N.V. The use of mirtazapine for the treatment of sleep disorders
WO2002036113A1 (en) * 2000-11-01 2002-05-10 Respiratorius Ab Composition comprising: serotonin receptor antagonists (5ht-2, 5ht-3) and agonist (5ht-4)
US6399310B1 (en) 2001-02-12 2002-06-04 Akzo Nobel N.V. Methods for improving the therapeutic response of humans having major depression and carrying the gene for apolipoprotein E4
US20030105082A1 (en) * 2001-12-03 2003-06-05 Murphy Greer Marechal Methods for improving the therapeutic response of humans having major depression and carrying the gene for apolipoprotein E4
US20040106124A1 (en) * 2001-02-12 2004-06-03 Murphy Greer M. Methods for improving the treatment of major depression by genotyping for the gene for apolipoproteine e4 and for improving the terapeutic response of humans having major depression and carrying the gene for apolipoprotein e4
EP1490073A4 (en) * 2002-03-21 2006-02-01 Martin C Hinz SEGMENT OPTIMIZATION TECHNOLOGY FOR THE SEROTONIN AND CATECHOLAMINE SYSTEM
US20070293571A1 (en) * 2006-06-08 2007-12-20 Hinz Martin C Adminstration of dopa precursors with sources of dopa to effectuate optimal catecholamine neurotransmitter outcomes
US20090311795A1 (en) * 2002-03-21 2009-12-17 Hinz Martin C Bilateral control of functions traditionally regulated by only serotonin or only dopamine
EP1558561A1 (en) * 2002-11-07 2005-08-03 Torrent Pharmaceuticals Ltd Process for preparation of polymorphic form of sertraline hydrochloride
CN1989968B (zh) 2002-12-27 2011-05-11 大塚制药株式会社 用于治疗情绪障碍的喹诺酮衍生物和5-羟色胺再摄取抑制剂
AR042806A1 (es) * 2002-12-27 2005-07-06 Otsuka Pharma Co Ltd Combinacion de derivados de carboestirilo e inhibidores de la reabsorcion de serotonina para el tratamiento de trastornos del animo
WO2004075724A2 (en) * 2003-02-21 2004-09-10 Hinz Martin C Serotonin and catecholamine system segment optimization technology
TW200502222A (en) * 2003-04-02 2005-01-16 Novartis Ag Use of 10-hydroxy-10,11-dihydrocarbamazepine derivatives for the treatment of affective disorders
EP1617832B1 (en) 2003-04-29 2008-03-12 Orexigen Therapeutics, Inc. Compositions for affecting weight loss
US20050234093A1 (en) * 2003-06-25 2005-10-20 H. Lundbeck A/S Treatment of depression and other affective disorders
US7838029B1 (en) * 2003-07-31 2010-11-23 Watson Laboratories, Inc. Mirtazapine solid dosage forms
US7390503B1 (en) 2003-08-22 2008-06-24 Barr Laboratories, Inc. Ondansetron orally disintegrating tablets
EP1667972B1 (en) 2003-09-10 2013-06-19 Brentwood Equities Ltd. Diastereomers of 4-aryloxy-3-hydroxypiperidines
US7713959B2 (en) * 2004-01-13 2010-05-11 Duke University Compositions of an anticonvulsant and mirtazapine to prevent weight gain
TW200538100A (en) * 2004-04-21 2005-12-01 Akzo Nobel Nv Mirtazapine salts
US20060039867A1 (en) * 2004-08-20 2006-02-23 Cypress Bioscience, Inc. Method for treating sleep-related breathing disorders with setiptiline
RU2283097C2 (ru) * 2004-11-16 2006-09-10 Эльвира Ивановна Белобородова Способ лечения бронхиальной астмы, сочетанной с эрозивно-язвенными поражениями гастродуоденальной зоны
WO2006055854A2 (en) * 2004-11-17 2006-05-26 Cypress Bioscience, Inc. Methods for reducing the side effects associated with mirtazapine treatment
BRPI0517847A (pt) * 2004-11-19 2008-10-21 Organon Nv combinação, usos de um inibidor de reabsorção de serotonina seletiva e de um antagonista do receptor de glicocorticóide, e, método para o tratamento de um indivìduo de uma espécie vertebrada sofrendo de depressão ou um distúrbio relacionado
CN101370488B (zh) 2005-11-22 2012-07-18 奥雷西根治疗公司 增加胰岛素敏感性的组合物
US8916195B2 (en) 2006-06-05 2014-12-23 Orexigen Therapeutics, Inc. Sustained release formulation of naltrexone
KR20170077291A (ko) 2006-11-09 2017-07-05 오렉시젠 세러퓨틱스 인크. 단위 용량 팩키지
DK2089005T3 (da) 2006-11-09 2010-07-19 Orexigen Therapeutics Inc Lagdelte farmaceutiske formuleringer omfattende et hurtigt opløsende mellemlag
EP2167096A4 (en) * 2007-06-13 2010-07-14 Cypress Bioscience Inc IMPROVING TOLERANCE TO MIRTAZAPINE AND A SECOND ACTIVE INGREDIENT BY THE COMBINED USE OF THEM
CN101332193B (zh) * 2007-06-29 2012-12-12 杭州民生药业有限公司 一种马来酸氟伏沙明药物组合物的制备方法
WO2009158114A1 (en) 2008-05-30 2009-12-30 Orexigen Therapeutics, Inc. Methods for treating visceral fat conditions
CN102459769B (zh) 2009-06-09 2014-03-26 住友重机械工业株式会社 混合式挖土机及其控制方法
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Also Published As

Publication number Publication date
PT813873E (pt) 2002-06-28
CN1132581C (zh) 2003-12-31
CZ290691B6 (cs) 2002-09-11
DE69710390D1 (de) 2002-03-21
HUP9701068A3 (en) 2000-07-28
JP2009137970A (ja) 2009-06-25
AR007609A1 (es) 1999-11-10
JPH1067663A (ja) 1998-03-10
HU225534B1 (en) 2007-02-28
IL121076A0 (en) 1997-11-20
NO972816L (no) 1997-12-22
ID17051A (id) 1997-12-04
HK1006081A1 (en) 1999-02-12
KR980000447A (ko) 1998-03-30
SG60073A1 (en) 1999-02-22
RU2181287C2 (ru) 2002-04-20
MX9704579A (es) 1998-07-31
ES2172744T3 (es) 2002-10-01
CN1173330A (zh) 1998-02-18
ATE213159T1 (de) 2002-02-15
CZ187097A3 (cs) 1998-01-14
PL188520B1 (pl) 2005-02-28
US5977099A (en) 1999-11-02
DK0813873T3 (da) 2002-05-27
CA2208199C (en) 2006-10-24
TR199700522A2 (xx) 1998-01-21
CA2208199A1 (en) 1997-12-19
BR9703624A (pt) 1998-09-01
PL320628A1 (en) 1997-12-22
NO972816D0 (no) 1997-06-18
ZA975335B (en) 1998-01-26
DE69710390T2 (de) 2002-08-14
JP4925074B2 (ja) 2012-04-25
AU2612997A (en) 1998-01-08
TR199700522A3 (tr) 1998-01-21
HUP9701068A2 (hu) 1998-08-28
HU9701068D0 (en) 1997-08-28
AU727851B2 (en) 2001-01-04
IL121076A (en) 2000-10-31
NO313177B1 (no) 2002-08-26
NZ328113A (en) 1999-09-29

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