KR100386709B1 - 신규한3-치환된3h-2,3-벤조디아제핀유도체,이의제조및약제로서의용도 - Google Patents

신규한3-치환된3h-2,3-벤조디아제핀유도체,이의제조및약제로서의용도 Download PDF

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Publication number
KR100386709B1
KR100386709B1 KR1019970700650A KR19970700650A KR100386709B1 KR 100386709 B1 KR100386709 B1 KR 100386709B1 KR 1019970700650 A KR1019970700650 A KR 1019970700650A KR 19970700650 A KR19970700650 A KR 19970700650A KR 100386709 B1 KR100386709 B1 KR 100386709B1
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KR
South Korea
Prior art keywords
alkyl
substituted
hydrogen
unsubstituted
same
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KR1019970700650A
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English (en)
Korean (ko)
Inventor
타마스 하모리
이스트반 타나바
산도르 솔리옴
팔 베르쩨니
에르쩨베트 비르카스 팔그리네
페렌크 안드라시
이스트반 링
티보르 하스코
가보르 카푸스
에메스 추쯔들
마르타 첼로시
프란시스카 에르도 빌다네
안탈 시마이
가보르 졸리오미
Original Assignee
쉐링 악티엔게젤샤프트
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Publication of KR100386709B1 publication Critical patent/KR100386709B1/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Toxicology (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KR1019970700650A 1994-08-01 1995-07-28 신규한3-치환된3h-2,3-벤조디아제핀유도체,이의제조및약제로서의용도 KR100386709B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEP4428835.2 1994-08-01
DE4428835A DE4428835A1 (de) 1994-08-01 1994-08-01 Neue 3-substituierte 3H-2,3-Benzodiazepinderivate, deren Herstellung und Verwendung als Arzneimittel

Publications (1)

Publication Number Publication Date
KR100386709B1 true KR100386709B1 (ko) 2003-08-19

Family

ID=6525693

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019970700650A KR100386709B1 (ko) 1994-08-01 1995-07-28 신규한3-치환된3h-2,3-벤조디아제핀유도체,이의제조및약제로서의용도

Country Status (21)

Country Link
US (1) US5756495A (ru)
EP (1) EP0775143B1 (ru)
JP (1) JPH10504543A (ru)
KR (1) KR100386709B1 (ru)
CN (1) CN1048728C (ru)
AT (1) ATE223415T1 (ru)
AU (1) AU693241B2 (ru)
CA (1) CA2195747C (ru)
CZ (1) CZ291276B6 (ru)
DE (2) DE4428835A1 (ru)
DK (1) DK0775143T3 (ru)
ES (1) ES2181787T3 (ru)
FI (1) FI113177B (ru)
HU (1) HU225500B1 (ru)
MX (1) MX9700813A (ru)
NO (1) NO319151B1 (ru)
NZ (1) NZ290777A (ru)
PT (1) PT775143E (ru)
RU (1) RU2146678C1 (ru)
SK (1) SK284103B6 (ru)
WO (1) WO1996004283A1 (ru)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP9701325A1 (hu) 1997-07-31 2000-08-28 Gyógyszerkutató Intézet Kft. Új 2,3-benzodiazepin-származékok
UA67749C2 (ru) * 1997-08-12 2004-07-15 Егіш Дьйодьсердьяр Рт. Производные 8-замещенного-9н-1,3-диоксол/4,5-h//2,3/бензодиазепина, которые являются ингибиторами амра/каинитного рецептора
NZ503301A (en) * 1997-08-12 2002-09-27 Egyt Gyogyszervegyeszeti Gyar 1,3-dioxolo[4,5-h][2,3]benzodiazepine derivatives useful as AMPA/Kainate receptor inhibitors
HU227128B1 (en) * 1999-07-07 2010-07-28 Egyt Gyogyszervegyeszeti Gyar New 2,3-benzodiazepine derivatives
NO320473B1 (no) * 2002-09-09 2005-12-12 Norsk Hydro As Anordning ved separator for separasjon av flerfasefluid.
US6858605B2 (en) 2003-02-04 2005-02-22 Ivax Drug Research Institute, Ltd. Substituted 2,3-benzodiazepine derivatives
GB0405034D0 (en) * 2004-03-05 2004-04-07 Novartis Ag Organic compounds
US20060270709A1 (en) * 2005-04-04 2006-11-30 Eisai Co. Ltd. Dihydropyridine compounds and compositions for headaches
BRPI0615906A2 (pt) * 2005-09-09 2011-05-31 Novartis Ag tratamento de doenças autoimunes
WO2015121268A1 (de) * 2014-02-14 2015-08-20 Bayer Pharma Aktiengesellschaft 1-phenyl-3h-2,3-benzodiazepine und ihre verwendung als bromodomänen-inhibitoren

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU219778B (hu) * 1990-12-21 2001-07-30 Gyógyszerkutató Intézet Közös Vállalat Eljárás N-acil-2,3-benzodiazepin-származékok, savaddíciós sóik és az ezeket tartalmazó gyógyászati készítmények előállítására, valamint a vegyületek egy csoportja, és az ezeket tartalmazó gyógyászati készítmények

Also Published As

Publication number Publication date
NO970435D0 (no) 1997-01-31
HU225500B1 (en) 2007-01-29
AU3160995A (en) 1996-03-04
PT775143E (pt) 2003-01-31
EP0775143B1 (de) 2002-09-04
ES2181787T3 (es) 2003-03-01
CA2195747A1 (en) 1996-02-15
JPH10504543A (ja) 1998-05-06
NO970435L (no) 1997-01-31
FI113177B (fi) 2004-03-15
DK0775143T3 (da) 2002-12-02
CZ291276B6 (cs) 2003-01-15
MX9700813A (es) 1997-05-31
SK284103B6 (sk) 2004-09-08
EP0775143A1 (de) 1997-05-28
NZ290777A (en) 1998-07-28
US5756495A (en) 1998-05-26
NO319151B1 (no) 2005-06-27
RU2146678C1 (ru) 2000-03-20
CA2195747C (en) 2006-01-24
CN1155285A (zh) 1997-07-23
WO1996004283A1 (de) 1996-02-15
CN1048728C (zh) 2000-01-26
ATE223415T1 (de) 2002-09-15
AU693241B2 (en) 1998-06-25
SK13597A3 (en) 1997-07-09
CZ15997A3 (en) 1997-06-11
FI970434A0 (fi) 1997-01-31
FI970434A (fi) 1997-01-31
DE59510364D1 (de) 2002-10-10
HUT76801A (en) 1997-11-28
DE4428835A1 (de) 1996-02-08

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