KR100361933B1 - 화학적으로정의된비중합성결합가플랫폼분자및그것의콘주게이트 - Google Patents

화학적으로정의된비중합성결합가플랫폼분자및그것의콘주게이트 Download PDF

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KR100361933B1
KR100361933B1 KR1019960701196A KR19960701196A KR100361933B1 KR 100361933 B1 KR100361933 B1 KR 100361933B1 KR 1019960701196 A KR1019960701196 A KR 1019960701196A KR 19960701196 A KR19960701196 A KR 19960701196A KR 100361933 B1 KR100361933 B1 KR 100361933B1
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South Korea
Prior art keywords
conjugate
compound
molecule
platform
mmol
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KR1019960701196A
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English (en)
Korean (ko)
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엠. 쿠츠 스티븐
에스. 죤즈 데이비드
알렌 리빙스톤 다글라스
유 린
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라 졸라 파마슈티칼 컴파니
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Priority claimed from US08/118,055 external-priority patent/US6060056A/en
Priority claimed from US08/152,506 external-priority patent/US5552391A/en
Application filed by 라 졸라 파마슈티칼 컴파니 filed Critical 라 졸라 파마슈티칼 컴파니
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Publication of KR100361933B1 publication Critical patent/KR100361933B1/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6093—Synthetic polymers, e.g. polyethyleneglycol [PEG], Polymers or copolymers of (D) glutamate and (D) lysine

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1019960701196A 1993-09-08 1994-09-08 화학적으로정의된비중합성결합가플랫폼분자및그것의콘주게이트 KR100361933B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US08/118055 1993-09-08
US08/118,055 US6060056A (en) 1991-02-08 1993-09-08 Composition for inducing humoral anergy to an immunogen comprising a T cell epitope-deficient analog of the immunogen conjugated to a nonimmunogenic valency platform molecule
US08/152,506 US5552391A (en) 1990-01-16 1993-11-15 Chemically-defined non-polymeric valency platform molecules and conjugates thereof
US08/152506 1993-11-15

Publications (1)

Publication Number Publication Date
KR100361933B1 true KR100361933B1 (ko) 2003-02-14

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Application Number Title Priority Date Filing Date
KR1019960701196A KR100361933B1 (ko) 1993-09-08 1994-09-08 화학적으로정의된비중합성결합가플랫폼분자및그것의콘주게이트

Country Status (2)

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US (4) US20020082400A1 (US07115581-20061003-C00015.png)
KR (1) KR100361933B1 (US07115581-20061003-C00015.png)

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US7115581B2 (en) 2006-10-03
US20020107389A1 (en) 2002-08-08
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US20030162953A1 (en) 2003-08-28
US20050026856A1 (en) 2005-02-03

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