KR100191774B1 - 피라졸로[1,5-알파] 피리미딘 유도체 및 이것을 함유하는 항염증제 - Google Patents

피라졸로[1,5-알파] 피리미딘 유도체 및 이것을 함유하는 항염증제 Download PDF

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Publication number
KR100191774B1
KR100191774B1 KR1019930703210A KR930703210A KR100191774B1 KR 100191774 B1 KR100191774 B1 KR 100191774B1 KR 1019930703210 A KR1019930703210 A KR 1019930703210A KR 930703210 A KR930703210 A KR 930703210A KR 100191774 B1 KR100191774 B1 KR 100191774B1
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KR
South Korea
Prior art keywords
group
lower alkyl
phenyl
pyrazolo
alkyl group
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Expired - Fee Related
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KR1019930703210A
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English (en)
Korean (ko)
Inventor
마꼬또 이노우에
긴지 하시모또
도시끼 구와하라
유끼오 수기모또
다꾸지 우에사꼬
도시아끼 후나또
Original Assignee
오스카 아끼히꼬
가부시끼가이샤 오스카 세이야꾸 고오죠
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
KR1019930703210A 1991-04-22 1991-08-06 피라졸로[1,5-알파] 피리미딘 유도체 및 이것을 함유하는 항염증제 Expired - Fee Related KR100191774B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP91-90707 1991-04-22
JP9070791 1991-04-22
PCT/JP1991/001043 WO1992018504A1 (en) 1991-04-22 1991-08-06 PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVE AND ANTI-INFLAMMATORY CONTAINING THE SAME

Publications (1)

Publication Number Publication Date
KR100191774B1 true KR100191774B1 (ko) 1999-06-15

Family

ID=14006001

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019930703210A Expired - Fee Related KR100191774B1 (ko) 1991-04-22 1991-08-06 피라졸로[1,5-알파] 피리미딘 유도체 및 이것을 함유하는 항염증제

Country Status (12)

Country Link
US (1) US5688949A (enExample)
EP (1) EP0591528B1 (enExample)
JP (1) JPH0570353A (enExample)
KR (1) KR100191774B1 (enExample)
AT (1) ATE174917T1 (enExample)
AU (1) AU651986B2 (enExample)
CA (1) CA2107479C (enExample)
DE (1) DE69130683T2 (enExample)
DK (1) DK0591528T3 (enExample)
ES (1) ES2126573T3 (enExample)
TW (1) TW221434B (enExample)
WO (1) WO1992018504A1 (enExample)

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US8580782B2 (en) 2002-09-04 2013-11-12 Merck Sharp & Dohme Corp. Substituted pyrazolo[1,5-a]pyrimidines as cyclin dependent kinase inhibitors
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US7205308B2 (en) * 2002-09-04 2007-04-17 Schering Corporation Trisubstituted 7-aminopyrazolopyrimidines as cyclin dependent kinase inhibitors
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US7196078B2 (en) * 2002-09-04 2007-03-27 Schering Corpoartion Trisubstituted and tetrasubstituted pyrazolopyrimidines as cyclin dependent kinase inhibitors
US8673924B2 (en) 2002-09-04 2014-03-18 Merck Sharp & Dohme Corp. Substituted pyrazolo[1,5-a]pyrimidines as cyclin dependent kinase inhibitors
US7161003B1 (en) 2002-09-04 2007-01-09 Schering Corporation Pyrazolopyrimidines as cyclin dependent kinase inhibitors
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EP1608652A1 (en) * 2003-03-31 2005-12-28 Vernalis (Cambridge) Limited Pyrazolopyrimidine compounds and their use in medicine
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PE20051089A1 (es) * 2004-01-22 2006-01-25 Novartis Ag Derivados de pirazolo [1,5-a] pirimidin-7-il-amina como inhibidores de quinasa de proteina
EP2392258B1 (en) 2005-04-28 2014-10-08 Proteus Digital Health, Inc. Pharma-informatics system
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US7776865B2 (en) 2005-10-06 2010-08-17 Schering Corporation Substituted pyrazolo[1,5-a]pyrimidines as protein kinase inhibitors
WO2007044426A2 (en) * 2005-10-06 2007-04-19 Schering Corporation Pyrazolopyrimidines as protein kinase inhibitors
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BRPI0719352A2 (pt) * 2006-11-29 2017-10-24 Abbott Lab inibidores de enzima diacilglicerol o-aciltransferase tipo 1
EP2690101B1 (en) * 2007-12-19 2015-06-24 Genentech, Inc. 5-Anilinoimidazopyridines and Methods of Use
PL3395372T3 (pl) 2009-02-20 2022-07-25 EnhanX Biopharm Inc. Układ do dostarczania leków na bazie glutationu
CN102458374A (zh) 2009-05-06 2012-05-16 实验室护肤股份有限公司 包含活性剂-磷酸钙颗粒复合物的皮肤递送组合物及其使用方法
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US8633198B1 (en) 2011-09-20 2014-01-21 Nant Holdings Ip, Llc Small molecule inhibitors of influenza A RNA-dependent RNA polymerase
EP3079693B1 (en) * 2013-12-11 2019-09-04 Nant Holdings IP, LLC Small molecule inhibitors of influenza a rna-dependent rna polymerase
CN106061975B (zh) * 2014-01-22 2019-09-24 库洛维公司 作为抗病毒化合物的吡唑并[1,5-a]嘧啶
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Also Published As

Publication number Publication date
AU651986B2 (en) 1994-08-11
TW221434B (enExample) 1994-03-01
EP0591528B1 (en) 1998-12-23
ES2126573T3 (es) 1999-04-01
DE69130683T2 (de) 1999-05-06
EP0591528A4 (en) 1995-02-15
CA2107479A1 (en) 1992-10-23
WO1992018504A1 (en) 1992-10-29
AU8295891A (en) 1992-11-17
CA2107479C (en) 1997-12-16
DE69130683D1 (de) 1999-02-04
DK0591528T3 (da) 1999-08-23
EP0591528A1 (en) 1994-04-13
ATE174917T1 (de) 1999-01-15
JPH0570353A (ja) 1993-03-23
US5688949A (en) 1997-11-18

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