KR0151783B1 - 신규의 프롤린 유도체 - Google Patents

신규의 프롤린 유도체

Info

Publication number
KR0151783B1
KR0151783B1 KR1019910012959A KR910012959A KR0151783B1 KR 0151783 B1 KR0151783 B1 KR 0151783B1 KR 1019910012959 A KR1019910012959 A KR 1019910012959A KR 910012959 A KR910012959 A KR 910012959A KR 0151783 B1 KR0151783 B1 KR 0151783B1
Authority
KR
South Korea
Prior art keywords
pyrrolidine
prolyl
compound
hydroxy
ethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1019910012959A
Other languages
English (en)
Korean (ko)
Other versions
KR920002589A (ko
Inventor
코지 고바야시
카주히코 니시이
쿠니오 이와타
이츠오 우찌다
Original Assignee
미즈노 시게루
닛폰 다바코산교 가부시키가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 미즈노 시게루, 닛폰 다바코산교 가부시키가이샤 filed Critical 미즈노 시게루
Publication of KR920002589A publication Critical patent/KR920002589A/ko
Application granted granted Critical
Publication of KR0151783B1 publication Critical patent/KR0151783B1/ko
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
KR1019910012959A 1990-07-27 1991-07-27 신규의 프롤린 유도체 Expired - Fee Related KR0151783B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP19783590 1990-07-27
JP197835 1990-07-27
JP418334 1990-12-27
JP41833490 1990-12-27

Publications (2)

Publication Number Publication Date
KR920002589A KR920002589A (ko) 1992-02-28
KR0151783B1 true KR0151783B1 (ko) 1998-10-15

Family

ID=26510594

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019910012959A Expired - Fee Related KR0151783B1 (ko) 1990-07-27 1991-07-27 신규의 프롤린 유도체

Country Status (3)

Country Link
EP (1) EP0468469A2 (enExample)
KR (1) KR0151783B1 (enExample)
CA (1) CA2048010C (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUT76640A (en) * 1995-08-17 1997-10-28 Chinoin Gyogyszer Es Vegyeszet Compounds of pharmaceutical activity cyclic amide derivatives, pharmaceutical compositions containing them, process for producing them and their use
HUP9700442A1 (hu) * 1997-02-14 1999-09-28 Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. Gyűrűs amidszármazékok, e vegyületeket tartalmazó gyógyászati készítmények, eljárás előállításukra és alkalmazásuk
DE10150203A1 (de) * 2001-10-12 2003-04-17 Probiodrug Ag Peptidylketone als Inhibitoren der DPIV
JP4806628B2 (ja) 2003-05-05 2011-11-02 プロビオドルグ エージー グルタミニルシクラーゼ阻害剤
WO2005049027A2 (en) 2003-11-03 2005-06-02 Probiodrug Ag Combinations useful for the treatment of neuronal disorders
KR101099206B1 (ko) 2004-02-05 2011-12-27 프로비오드룩 아게 신규한 글루타미닐 시클라제 저해제
US8278345B2 (en) 2006-11-09 2012-10-02 Probiodrug Ag Inhibitors of glutaminyl cyclase
JP5523107B2 (ja) 2006-11-30 2014-06-18 プロビオドルグ エージー グルタミニルシクラーゼの新規阻害剤
EP2481408A3 (en) 2007-03-01 2013-01-09 Probiodrug AG New use of glutaminyl cyclase inhibitors
WO2008128985A1 (en) 2007-04-18 2008-10-30 Probiodrug Ag Thiourea derivatives as glutaminyl cyclase inhibitors
MX2012002993A (es) 2009-09-11 2012-04-19 Probiodrug Ag Derivados heterociclicos como inhibidores de ciclasa glutaminilo.
JP6026284B2 (ja) 2010-03-03 2016-11-16 プロビオドルグ エージー グルタミニルシクラーゼの阻害剤
US8269019B2 (en) 2010-03-10 2012-09-18 Probiodrug Ag Inhibitors
WO2011131748A2 (en) 2010-04-21 2011-10-27 Probiodrug Ag Novel inhibitors
ES2570167T3 (es) 2011-03-16 2016-05-17 Probiodrug Ag Derivados de benzimidazol como inhibidores de glutaminil ciclasa
PL3461819T3 (pl) 2017-09-29 2020-11-30 Probiodrug Ag Inhibitory cyklazy glutaminylowej

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0268190B1 (en) * 1986-11-20 1993-06-16 Ono Pharmaceutical Co., Ltd. Prolinal derivatives
JPH0774194B2 (ja) * 1987-06-11 1995-08-09 財団法人微生物化学研究会 生理活性を有する新規なアクチノニン誘導体
US5053414A (en) * 1988-04-08 1991-10-01 Ono Pharmaceutical Co., Ltd. Heterocyclic compounds

Also Published As

Publication number Publication date
CA2048010C (en) 1998-08-25
CA2048010A1 (en) 1992-01-28
EP0468469A2 (en) 1992-01-29
EP0468469A3 (enExample) 1994-01-19
KR920002589A (ko) 1992-02-28

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