KE2988A - 4-substituted quinazoline cardiac stimulants - Google Patents

4-substituted quinazoline cardiac stimulants

Info

Publication number
KE2988A
KE2988A KE2988A KE298879A KE2988A KE 2988 A KE2988 A KE 2988A KE 2988 A KE2988 A KE 2988A KE 298879 A KE298879 A KE 298879A KE 2988 A KE2988 A KE 2988A
Authority
KE
Kenya
Prior art keywords
substituted quinazoline
cardiac stimulants
stimulants
cardiac
quinazoline
Prior art date
Application number
KE2988A
Other languages
English (en)
Inventor
C Thomson
A G Evans
J C Danilewicz
A L Ham
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Publication of KE2988A publication Critical patent/KE2988A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
KE2988A 1974-07-25 1979-09-05 4-substituted quinazoline cardiac stimulants KE2988A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB3280574 1974-07-25
GB41675*[A GB1460389A (en) 1974-07-25 1975-01-06 4-substituted quinazoline cardiac stimulants

Publications (1)

Publication Number Publication Date
KE2988A true KE2988A (en) 1979-09-28

Family

ID=26235904

Family Applications (1)

Application Number Title Priority Date Filing Date
KE2988A KE2988A (en) 1974-07-25 1979-09-05 4-substituted quinazoline cardiac stimulants

Country Status (23)

Country Link
US (1) US4001422A (fr)
JP (1) JPS5527062B2 (fr)
AR (7) AR216046A1 (fr)
BG (2) BG27086A3 (fr)
CA (1) CA1060445A (fr)
CH (2) CH611616A5 (fr)
DD (1) DD119046A5 (fr)
DE (1) DE2530894C2 (fr)
DK (1) DK138800B (fr)
FI (1) FI66182C (fr)
FR (1) FR2279406A1 (fr)
GB (1) GB1460389A (fr)
HK (1) HK61879A (fr)
IE (1) IE41838B1 (fr)
IL (1) IL47625A (fr)
KE (1) KE2988A (fr)
LU (1) LU73072A1 (fr)
MY (1) MY8000108A (fr)
NL (1) NL159982C (fr)
PH (1) PH14190A (fr)
RO (3) RO71841A (fr)
SE (1) SE420921B (fr)
YU (3) YU37155B (fr)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN148482B (fr) 1977-06-03 1981-03-07 Pfizer
US4370328A (en) * 1977-11-03 1983-01-25 Pfizer Inc. Cardiac stimulant 1-(3- or 4-substituted piperidino)phthalazines
CA1086735A (fr) * 1977-11-03 1980-09-30 John C. Danilewicz Piperidino-quinazolines
US4489075A (en) * 1982-05-15 1984-12-18 Pfizer Inc. Cyclic sulfonamidoalkyl substituted 4-piperidinoquinazoline cardiac stimulants
JPS61215389A (ja) * 1985-03-20 1986-09-25 Kyowa Hakko Kogyo Co Ltd キナゾリン誘導体およびそれを含有する強心剤
US6645969B1 (en) * 1991-05-10 2003-11-11 Aventis Pharmaceuticals Inc. Aryl and heteroaryl quinazoline compounds which inhibit CSF-1R receptor tyrosine kinase
FR2802206B1 (fr) 1999-12-14 2005-04-22 Sod Conseils Rech Applic Derives de 4-aminopiperidine et leur utilisation en tant que medicament
TWI283665B (en) * 2001-09-13 2007-07-11 Smithkline Beecham Plc Novel urea compound, pharmaceutical composition containing the same and its use
HUP0200849A2 (hu) * 2002-03-06 2004-08-30 Sanofi-Synthelabo N-aminoacetil-2-ciano-pirrolidin-származékok, e vegyületeket tartalmazó gyógyszerkészítmények és eljárás előállításukra
US7064211B2 (en) * 2002-03-22 2006-06-20 Eisai Co., Ltd. Hemiasterlin derivatives and uses thereof
WO2004024710A1 (fr) * 2002-09-13 2004-03-25 Glaxo Group Limited Composes a base d'uree, actifs en tant qu'antagonistes du recepteur de la vanilloide et utilises pour traiter les douleurs
TWI350168B (en) 2004-05-07 2011-10-11 Incyte Corp Amido compounds and their use as pharmaceuticals
AU2005258248A1 (en) * 2004-06-24 2006-01-05 Incyte Corporation Amido compounds and their use as pharmaceuticals
EA200700117A1 (ru) 2004-06-24 2007-06-29 Инсайт Корпорейшн N-замещенные пиперидины и их применение в качестве фармацевтических препаратов
US7687665B2 (en) * 2004-06-24 2010-03-30 Incyte Corporation 2-methylprop anamides and their use as pharmaceuticals
JP2008504279A (ja) * 2004-06-24 2008-02-14 インサイト・コーポレイション アミド化合物およびその医薬としての使用
US20060019975A1 (en) * 2004-07-23 2006-01-26 Pfizer Inc Novel piperidyl derivatives of quinazoline and isoquinoline
MX2007001540A (es) * 2004-08-10 2007-04-23 Incyte Corp Compuestos amido y sus usos como farmaceuticos.
US8071768B2 (en) * 2005-06-10 2011-12-06 Janssen Pharmaceutica, N.V. Alkylquinoline and alkylquinazoline kinase modulators
US7825244B2 (en) * 2005-06-10 2010-11-02 Janssen Pharmaceutica Nv Intermediates useful in the synthesis of alkylquinoline and alkylquinazoline kinase modulators, and related methods of synthesis
US20070213311A1 (en) * 2006-03-02 2007-09-13 Yun-Long Li Modulators of 11-beta hydroxyl steroid dehydrogenase type 1, pharmaceutical compositions thereof, and methods of using the same
WO2007103719A2 (fr) * 2006-03-03 2007-09-13 Incyte Corporation MODULATEURS DE LA 11-β-HYDROXYSTÉROÏDE DÉSHYDROGÉNASE DE TYPE 1, LEURS COMPOSITIONS PHARMACEUTIQUES ET LEURS PROCÉDÉS D'UTILISATION
CA2649677A1 (fr) * 2006-05-01 2007-11-15 Incyte Corporation Urees tetrasubstituees modulateurs de la 11-.beta. hydroxyl steroid deshydrogenase de type 1
WO2007137066A2 (fr) * 2006-05-17 2007-11-29 Incyte Corporation Inhibiteurs hétérocycliques de la déshydrogénase du stéroïde hydroxyle 11-b de type 1 et leurs procédés d'utilisation
EP1903038A1 (fr) * 2006-09-07 2008-03-26 Bayer Schering Pharma Aktiengesellschaft Dérivés N-(1-hetaryl-piperidine-4-yl)-(het)arylamide utilisées comme modulateurs du recepteur EP2
EP1903037A1 (fr) * 2006-09-07 2008-03-26 Bayer Schering Pharma Aktiengesellschaft Dérivés de 1-[(hétéro)aryl]-3-[hétéroaryl-pipéridine-4-yl]thiourée en tant que modulateurs de récepteurs EP2
WO2020160333A1 (fr) * 2019-02-01 2020-08-06 The Board Of Trustees Of The Leland Stanford Junior University Inhibiteurs d'enpp1 et méthodes de modulation de réponse immunitaire
EP3941459A4 (fr) * 2019-03-19 2022-11-30 Stingray Therapeutics, Inc. Composés de quinoléine et de quinazoline et leurs procédés d'utilisation

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1156973A (en) * 1965-07-06 1969-07-02 Quinazoline Derivatives
US3517005A (en) * 1967-10-26 1970-06-23 Pfizer & Co C Certain 2- and 4-substituted quinazolines
US3511836A (en) * 1967-12-13 1970-05-12 Pfizer & Co C 2,4,6,7-tetra substituted quinazolines
US3637701A (en) * 1969-03-03 1972-01-25 Sandoz Ag Certain nitrate derivatives of 4-aminoquinazolines
DE2121031A1 (en) * 1971-04-29 1972-11-02 Dr. Karl Thomae Gmbh, 7950 Biberach Base-substd quinazolines - thrombocyte aggregation inhibitors
BE793371A (fr) * 1971-12-27 1973-06-27 Sandoz Sa Nouveaux derives de la 4-amino-quinazoline, leur preparation etmedicaments contenant ces
US3819628A (en) * 1972-07-31 1974-06-25 Sandoz Ag 2-phenyl-4-substituted amino-quinazolines and nitrates thereof
US3838127A (en) * 1972-10-19 1974-09-24 Sandoz Ag 4-(4-(hydroxyalkyl)-1-piperazino)-quinazoline benzoates
GB1417029A (en) * 1973-03-07 1975-12-10 Pfizer Ltd Quinazoline-derived amines

Also Published As

Publication number Publication date
US4001422A (en) 1977-01-04
BG27086A3 (fr) 1979-08-15
AR213407A1 (es) 1979-01-31
DK138800B (da) 1978-10-30
SE7508101L (sv) 1976-01-26
SE420921B (sv) 1981-11-09
FR2279406B1 (fr) 1980-04-30
DD119046A5 (fr) 1976-04-05
JPS5527062B2 (fr) 1980-07-17
IE41838L (en) 1976-01-25
NL159982B (nl) 1979-04-17
RO69296A (fr) 1981-08-30
FI752104A (fr) 1976-01-26
FI66182C (fi) 1984-09-10
AR215882A1 (es) 1979-11-15
DE2530894C2 (de) 1983-12-22
DK138800C (fr) 1979-04-09
JPS5136469A (fr) 1976-03-27
YU124181A (en) 1983-04-30
FI66182B (fi) 1984-05-31
FR2279406A1 (fr) 1976-02-20
IL47625A (en) 1981-01-30
AR216046A1 (es) 1979-11-30
RO71841A (fr) 1980-08-15
NL159982C (nl) 1979-09-17
AR212447A1 (es) 1978-07-14
AU8317475A (en) 1977-01-20
AR214049A1 (es) 1979-04-30
GB1460389A (en) 1977-01-06
CH608803A5 (fr) 1979-01-31
IE41838B1 (en) 1980-04-09
LU73072A1 (fr) 1977-03-24
AR214050A1 (es) 1979-04-30
YU37155B (en) 1984-08-31
CH611616A5 (fr) 1979-06-15
IL47625A0 (en) 1975-10-15
HK61879A (en) 1979-09-07
NL7508824A (nl) 1976-01-27
RO71840A (fr) 1982-09-09
YU124281A (en) 1983-04-30
YU184275A (en) 1983-04-27
AR207895A1 (es) 1976-11-08
DE2530894A1 (de) 1976-02-05
MY8000108A (en) 1980-12-31
PH14190A (en) 1981-03-26
CA1060445A (fr) 1979-08-14
DK337175A (fr) 1976-01-26
BG27744A3 (en) 1979-12-12

Similar Documents

Publication Publication Date Title
KE2988A (en) 4-substituted quinazoline cardiac stimulants
TR18704A (tr) Triazol tuerevleri
FR2273511A1 (fr) Stimulateur cardiaque
BE834837A (fr) Phenylpyrimidines
AU8622775A (en) Putter
IL48593A0 (en) Novel 1-substituted-4-benzylidenepiperidine derivatives
ZA753968B (en) Novel benzimidazolinone derivatives
BE824071A (fr) Stimulateur cardiaque suppletif
JPS5188901A (en) Futsusonyoru cc futsusoka
AU8265875A (en) Construction of soles
ZA75134B (en) Quinazoline derivatives
FR2293915A1 (fr) Stimulateur cardiaque
AU7733975A (en) New thioamides
AU8308575A (en) Trocar
ZA756594B (en) Roof-support unit of the caving shield type
BG28848A3 (en) Mptod of obtaining of 6- chlorine- 2- chlormethane- 4- phenylhynazolin- 3- oxide
IT1043986B (it) Scaffalatura
IL48695A0 (en) The preparation of alpha-oxothiodimethylamides
AU8639575A (en) Biocides
JPS5387393A (en) New heterocyclic compound
JPS51105288A (en) Vor kokuenjohoshikinomogi vor shingomaakingusochiojusuruchijokyoku
SU547594A1 (ru) Выт жной шкаф
JPS5173014A (en) Seramitsukuhyomenni ti okyokonihifukusuruhoho
IL48632A0 (en) The preparation of trichlorothiazole
ZA754000B (en) Novel benzcycloamide derivatives