HK61879A - 4-substituted quinazoline cardiac stimulants - Google Patents

4-substituted quinazoline cardiac stimulants

Info

Publication number
HK61879A
HK61879A HK618/79A HK61879A HK61879A HK 61879 A HK61879 A HK 61879A HK 618/79 A HK618/79 A HK 618/79A HK 61879 A HK61879 A HK 61879A HK 61879 A HK61879 A HK 61879A
Authority
HK
Hong Kong
Prior art keywords
substituted quinazoline
cardiac stimulants
stimulants
cardiac
quinazoline
Prior art date
Application number
HK618/79A
Other languages
English (en)
Inventor
A G Evans
A L Ham
J C Danilewicz
C Thomson
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Publication of HK61879A publication Critical patent/HK61879A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK618/79A 1974-07-25 1979-08-30 4-substituted quinazoline cardiac stimulants HK61879A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB3280574 1974-07-25
GB41675*[A GB1460389A (en) 1974-07-25 1975-01-06 4-substituted quinazoline cardiac stimulants

Publications (1)

Publication Number Publication Date
HK61879A true HK61879A (en) 1979-09-07

Family

ID=26235904

Family Applications (1)

Application Number Title Priority Date Filing Date
HK618/79A HK61879A (en) 1974-07-25 1979-08-30 4-substituted quinazoline cardiac stimulants

Country Status (23)

Country Link
US (1) US4001422A (fr)
JP (1) JPS5527062B2 (fr)
AR (7) AR216046A1 (fr)
BG (2) BG27086A3 (fr)
CA (1) CA1060445A (fr)
CH (2) CH611616A5 (fr)
DD (1) DD119046A5 (fr)
DE (1) DE2530894C2 (fr)
DK (1) DK138800B (fr)
FI (1) FI66182C (fr)
FR (1) FR2279406A1 (fr)
GB (1) GB1460389A (fr)
HK (1) HK61879A (fr)
IE (1) IE41838B1 (fr)
IL (1) IL47625A (fr)
KE (1) KE2988A (fr)
LU (1) LU73072A1 (fr)
MY (1) MY8000108A (fr)
NL (1) NL159982C (fr)
PH (1) PH14190A (fr)
RO (3) RO71840A (fr)
SE (1) SE420921B (fr)
YU (3) YU37155B (fr)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN148482B (fr) 1977-06-03 1981-03-07 Pfizer
CA1086735A (fr) * 1977-11-03 1980-09-30 John C. Danilewicz Piperidino-quinazolines
US4370328A (en) * 1977-11-03 1983-01-25 Pfizer Inc. Cardiac stimulant 1-(3- or 4-substituted piperidino)phthalazines
US4489075A (en) * 1982-05-15 1984-12-18 Pfizer Inc. Cyclic sulfonamidoalkyl substituted 4-piperidinoquinazoline cardiac stimulants
JPS61215389A (ja) * 1985-03-20 1986-09-25 Kyowa Hakko Kogyo Co Ltd キナゾリン誘導体およびそれを含有する強心剤
US6645969B1 (en) * 1991-05-10 2003-11-11 Aventis Pharmaceuticals Inc. Aryl and heteroaryl quinazoline compounds which inhibit CSF-1R receptor tyrosine kinase
FR2802206B1 (fr) * 1999-12-14 2005-04-22 Sod Conseils Rech Applic Derives de 4-aminopiperidine et leur utilisation en tant que medicament
PE20030417A1 (es) * 2001-09-13 2003-08-06 Smithkline Beecham Plc Derivados de urea como antagonistas del receptor vainilloide
HUP0200849A2 (hu) * 2002-03-06 2004-08-30 Sanofi-Synthelabo N-aminoacetil-2-ciano-pirrolidin-származékok, e vegyületeket tartalmazó gyógyszerkészítmények és eljárás előállításukra
US7064211B2 (en) * 2002-03-22 2006-06-20 Eisai Co., Ltd. Hemiasterlin derivatives and uses thereof
AU2003270199A1 (en) * 2002-09-13 2004-04-30 Glaxo Group Limited Urea compounds active as vanilloid receptor antagonists for the treatment of pain
TWI350168B (en) 2004-05-07 2011-10-11 Incyte Corp Amido compounds and their use as pharmaceuticals
EP1758580A4 (fr) * 2004-06-24 2008-01-16 Incyte Corp Piperidines a substitution n et utilisation de ces dernieres en tant que substances pharmaceutiques
EP1773773A4 (fr) * 2004-06-24 2009-07-29 Incyte Corp Composes amido et leur utilisation en tant que produits pharmaceutiques
NZ551602A (en) * 2004-06-24 2010-11-26 Incyte Corp Amido compounds and their use as pharmaceuticals
US7687665B2 (en) * 2004-06-24 2010-03-30 Incyte Corporation 2-methylprop anamides and their use as pharmaceuticals
US20060019975A1 (en) * 2004-07-23 2006-01-26 Pfizer Inc Novel piperidyl derivatives of quinazoline and isoquinoline
BRPI0514230A (pt) * 2004-08-10 2008-06-03 Incyte Corp compostos de amido e seu uso como produtos farmacêuticos
US7825244B2 (en) * 2005-06-10 2010-11-02 Janssen Pharmaceutica Nv Intermediates useful in the synthesis of alkylquinoline and alkylquinazoline kinase modulators, and related methods of synthesis
US8071768B2 (en) * 2005-06-10 2011-12-06 Janssen Pharmaceutica, N.V. Alkylquinoline and alkylquinazoline kinase modulators
TW200808807A (en) * 2006-03-02 2008-02-16 Incyte Corp Modulators of 11-β hydroxyl steroid dehydrogenase type 1, pharmaceutical compositions thereof, and methods of using the same
US20070208001A1 (en) * 2006-03-03 2007-09-06 Jincong Zhuo Modulators of 11- beta hydroxyl steroid dehydrogenase type 1, pharmaceutical compositions thereof, and methods of using the same
EP2013163A1 (fr) * 2006-05-01 2009-01-14 Incyte Corporation Urées tétrasubstituées modulateurs de la 11-beta hydroxyl stéroïd déshydrogénase de type 1
WO2007137066A2 (fr) * 2006-05-17 2007-11-29 Incyte Corporation Inhibiteurs hétérocycliques de la déshydrogénase du stéroïde hydroxyle 11-b de type 1 et leurs procédés d'utilisation
EP1903037A1 (fr) * 2006-09-07 2008-03-26 Bayer Schering Pharma Aktiengesellschaft Dérivés de 1-[(hétéro)aryl]-3-[hétéroaryl-pipéridine-4-yl]thiourée en tant que modulateurs de récepteurs EP2
EP1903038A1 (fr) * 2006-09-07 2008-03-26 Bayer Schering Pharma Aktiengesellschaft Dérivés N-(1-hetaryl-piperidine-4-yl)-(het)arylamide utilisées comme modulateurs du recepteur EP2
CN113677350A (zh) * 2019-02-01 2021-11-19 里兰斯坦福初级大学理事会 Enpp1抑制剂和调节免疫反应的方法
EP3941459A4 (fr) * 2019-03-19 2022-11-30 Stingray Therapeutics, Inc. Composés de quinoléine et de quinazoline et leurs procédés d'utilisation

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1156973A (en) * 1965-07-06 1969-07-02 Quinazoline Derivatives
US3517005A (en) * 1967-10-26 1970-06-23 Pfizer & Co C Certain 2- and 4-substituted quinazolines
US3511836A (en) * 1967-12-13 1970-05-12 Pfizer & Co C 2,4,6,7-tetra substituted quinazolines
US3637701A (en) * 1969-03-03 1972-01-25 Sandoz Ag Certain nitrate derivatives of 4-aminoquinazolines
DE2121031A1 (en) * 1971-04-29 1972-11-02 Dr. Karl Thomae Gmbh, 7950 Biberach Base-substd quinazolines - thrombocyte aggregation inhibitors
BE793371A (fr) * 1971-12-27 1973-06-27 Sandoz Sa Nouveaux derives de la 4-amino-quinazoline, leur preparation etmedicaments contenant ces
US3819628A (en) * 1972-07-31 1974-06-25 Sandoz Ag 2-phenyl-4-substituted amino-quinazolines and nitrates thereof
US3838127A (en) * 1972-10-19 1974-09-24 Sandoz Ag 4-(4-(hydroxyalkyl)-1-piperazino)-quinazoline benzoates
GB1417029A (en) * 1973-03-07 1975-12-10 Pfizer Ltd Quinazoline-derived amines

Also Published As

Publication number Publication date
AR214049A1 (es) 1979-04-30
FI752104A (fr) 1976-01-26
RO71841A (fr) 1980-08-15
LU73072A1 (fr) 1977-03-24
FR2279406A1 (fr) 1976-02-20
CH611616A5 (fr) 1979-06-15
CA1060445A (fr) 1979-08-14
YU124281A (en) 1983-04-30
AR215882A1 (es) 1979-11-15
JPS5136469A (fr) 1976-03-27
BG27744A3 (en) 1979-12-12
IL47625A (en) 1981-01-30
DK337175A (fr) 1976-01-26
DK138800C (fr) 1979-04-09
MY8000108A (en) 1980-12-31
SE420921B (sv) 1981-11-09
KE2988A (en) 1979-09-28
AR214050A1 (es) 1979-04-30
AR216046A1 (es) 1979-11-30
RO71840A (fr) 1982-09-09
IL47625A0 (en) 1975-10-15
YU124181A (en) 1983-04-30
SE7508101L (sv) 1976-01-26
BG27086A3 (bg) 1979-08-15
DE2530894A1 (de) 1976-02-05
IE41838B1 (en) 1980-04-09
FI66182C (fi) 1984-09-10
JPS5527062B2 (fr) 1980-07-17
FI66182B (fi) 1984-05-31
NL7508824A (nl) 1976-01-27
AU8317475A (en) 1977-01-20
DD119046A5 (fr) 1976-04-05
PH14190A (en) 1981-03-26
RO69296A (fr) 1981-08-30
DE2530894C2 (de) 1983-12-22
DK138800B (da) 1978-10-30
AR207895A1 (es) 1976-11-08
FR2279406B1 (fr) 1980-04-30
US4001422A (en) 1977-01-04
NL159982B (nl) 1979-04-17
YU37155B (en) 1984-08-31
IE41838L (en) 1976-01-25
YU184275A (en) 1983-04-27
NL159982C (nl) 1979-09-17
AR212447A1 (es) 1978-07-14
AR213407A1 (es) 1979-01-31
GB1460389A (en) 1977-01-06
CH608803A5 (fr) 1979-01-31

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