JPWO2023178202A5 - - Google Patents
Info
- Publication number
- JPWO2023178202A5 JPWO2023178202A5 JP2024555107A JP2024555107A JPWO2023178202A5 JP WO2023178202 A5 JPWO2023178202 A5 JP WO2023178202A5 JP 2024555107 A JP2024555107 A JP 2024555107A JP 2024555107 A JP2024555107 A JP 2024555107A JP WO2023178202 A5 JPWO2023178202 A5 JP WO2023178202A5
- Authority
- JP
- Japan
- Prior art keywords
- disease
- alkyl
- syndrome
- compound according
- bifunctional compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17/695,645 | 2022-03-15 | ||
| US17/695,645 US12485178B2 (en) | 2018-04-09 | 2022-03-15 | Bifunctional small molecules to target the selective degradation of circulating proteins |
| PCT/US2023/064470 WO2023178202A2 (en) | 2022-03-15 | 2023-03-15 | Bifunctional small molecules to target the selective degradation of circulating proteins |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2025509730A JP2025509730A (ja) | 2025-04-11 |
| JP2025509730A5 JP2025509730A5 (https=) | 2026-03-24 |
| JPWO2023178202A5 true JPWO2023178202A5 (https=) | 2026-03-24 |
Family
ID=88024440
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024555107A Pending JP2025509730A (ja) | 2022-03-15 | 2023-03-15 | 循環タンパク質の選択的分解を目的とした二官能性小分子 |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP4493222A2 (https=) |
| JP (1) | JP2025509730A (https=) |
| KR (1) | KR20240166514A (https=) |
| CN (1) | CN119255822A (https=) |
| AU (1) | AU2023236291A1 (https=) |
| IL (1) | IL315579A (https=) |
| MX (1) | MX2024011338A (https=) |
| WO (1) | WO2023178202A2 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2022310356A1 (en) | 2021-07-14 | 2024-01-25 | Lycia Therapeutics, Inc. | Asgpr cell surface receptor binding compounds and conjugates |
| WO2025219911A1 (en) * | 2024-04-16 | 2025-10-23 | Biohaven Therapeutics Ltd. | Treatment of diseases with monoclonal antibody drugs and molecular degraders |
| WO2025248469A1 (en) * | 2024-05-28 | 2025-12-04 | Biohaven Therapeutics Ltd. | TREATMENT OF IgG-RELATED DISEASES |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2997444A1 (en) * | 2015-09-29 | 2017-04-06 | Amgen Inc. | Asgr inhibitors for reducing cholesterol levels |
| US12364766B2 (en) * | 2018-04-09 | 2025-07-22 | Yale University | Bifunctional small molecules to target the selective degradation of circulating proteins |
| WO2019199621A1 (en) * | 2018-04-09 | 2019-10-17 | Yale University | Bi-functional molecules to degrade circulating proteins |
| CN113301925A (zh) * | 2018-12-19 | 2021-08-24 | 小利兰·斯坦福大学理事会 | 用于溶酶体靶向的双官能分子以及相关的组合物和方法 |
| IL294515A (en) * | 2020-01-31 | 2022-09-01 | Avilar Therapeutics Inc | Compounds bind asgpr to degrade extracellular proteins |
-
2023
- 2023-03-15 IL IL315579A patent/IL315579A/en unknown
- 2023-03-15 WO PCT/US2023/064470 patent/WO2023178202A2/en not_active Ceased
- 2023-03-15 AU AU2023236291A patent/AU2023236291A1/en active Pending
- 2023-03-15 CN CN202380040388.5A patent/CN119255822A/zh active Pending
- 2023-03-15 KR KR1020247034017A patent/KR20240166514A/ko active Pending
- 2023-03-15 JP JP2024555107A patent/JP2025509730A/ja active Pending
- 2023-03-15 EP EP23771648.5A patent/EP4493222A2/en active Pending
-
2024
- 2024-09-13 MX MX2024011338A patent/MX2024011338A/es unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| WO2019199621A4 (en) | Bi-functional molecules to degrade circulating proteins | |
| JP2021521192A5 (https=) | ||
| JP6703583B2 (ja) | 高活性抗新生物薬及び抗増殖剤 | |
| JP2023175957A5 (https=) | ||
| RU2018105094A (ru) | Модуляторы протеолиза на основе аланина и связанные с ними способы применения | |
| WO2019199634A4 (en) | Bifunctional small molecules to target the selective degradation of circulating proteins | |
| IL319363A (en) | Cervalon ligands and bifunctional compounds containing them | |
| JP2011515478A5 (https=) | ||
| JPWO2019199816A5 (https=) | ||
| RU2020139890A (ru) | Имидные модуляторы протеолиза и способы их применения | |
| JP2017513862A5 (https=) | ||
| JP2022526895A (ja) | 有橋三環式カルバモイルピリドン化合物およびその薬学的使用 | |
| JP2021519337A (ja) | Ikarosの分解のためのセレブロン結合剤 | |
| IL323835A (en) | Bifunctional small molecules to target the selective degradation of circulating proteins | |
| RU2017145267A (ru) | Модуляторы протеолиза на основе имидов и связанные с ними способы применения | |
| RU2014133019A (ru) | Соединения и способы усиления деградации белков-мишеней и других полипептидов с помощью е3 убиквитин лигазы | |
| JP2016519091A5 (https=) | ||
| JP2011519868A5 (https=) | ||
| EP3826675A1 (en) | Nanoparticle compositions | |
| JP2014516964A5 (https=) | ||
| JPWO2023178202A5 (https=) | ||
| JPWO2021055705A5 (https=) | ||
| WO2021146211A1 (en) | Nanoparticle compositions | |
| JPWO2023178179A5 (https=) | ||
| TW202342442A (zh) | Raf激酶抑制劑及其使用方法 |