JPWO2023132369A5 - - Google Patents
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- Publication number
- JPWO2023132369A5 JPWO2023132369A5 JP2023572495A JP2023572495A JPWO2023132369A5 JP WO2023132369 A5 JPWO2023132369 A5 JP WO2023132369A5 JP 2023572495 A JP2023572495 A JP 2023572495A JP 2023572495 A JP2023572495 A JP 2023572495A JP WO2023132369 A5 JPWO2023132369 A5 JP WO2023132369A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- oxa
- benzoxazin
- octan
- azabicyclo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025061016A JP2025106358A (ja) | 2022-01-07 | 2025-04-02 | Ｎｒｆ２活性化作用を有する含窒素複素環化合物 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022001804 | 2022-01-07 | ||
| JP2022001804 | 2022-01-07 | ||
| PCT/JP2023/000211 WO2023132369A1 (ja) | 2022-01-07 | 2023-01-06 | Ｎｒｆ２活性化作用を有する含窒素複素環化合物 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025061016A Division JP2025106358A (ja) | 2022-01-07 | 2025-04-02 | Ｎｒｆ２活性化作用を有する含窒素複素環化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPWO2023132369A1 JPWO2023132369A1 (https=) | 2023-07-13 |
| JPWO2023132369A5 true JPWO2023132369A5 (https=) | 2025-01-30 |
| JP7661533B2 JP7661533B2 (ja) | 2025-04-14 |
Family
ID=87073790
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023572495A Active JP7661533B2 (ja) | 2022-01-07 | 2023-01-06 | Ｎｒｆ２活性化作用を有する含窒素複素環化合物 |
| JP2025061016A Pending JP2025106358A (ja) | 2022-01-07 | 2025-04-02 | Ｎｒｆ２活性化作用を有する含窒素複素環化合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025061016A Pending JP2025106358A (ja) | 2022-01-07 | 2025-04-02 | Ｎｒｆ２活性化作用を有する含窒素複素環化合物 |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US20250084093A1 (https=) |
| EP (1) | EP4446312A4 (https=) |
| JP (2) | JP7661533B2 (https=) |
| KR (1) | KR20240133727A (https=) |
| CN (1) | CN118488944A (https=) |
| AR (1) | AR128216A1 (https=) |
| AU (1) | AU2023204960A1 (https=) |
| CA (1) | CA3246898A1 (https=) |
| CL (1) | CL2024001687A1 (https=) |
| CO (1) | CO2024007707A2 (https=) |
| CR (1) | CR20240325A (https=) |
| IL (1) | IL312793A (https=) |
| MX (1) | MX2024008480A (https=) |
| PE (1) | PE20241779A1 (https=) |
| TW (1) | TW202340204A (https=) |
| WO (1) | WO2023132369A1 (https=) |
| ZA (1) | ZA202406044B (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024262491A1 (ja) * | 2023-06-19 | 2024-12-26 | 中外製薬株式会社 | Ｎｒｆ２活性化作用を有する含窒素複素環化合物の結晶 |
| CN118221551A (zh) * | 2024-04-10 | 2024-06-21 | 南京艾康生物科技有限公司 | 4-甲酰苄基氨基甲酸叔丁酯的制备方法 |
| CN119684220A (zh) * | 2024-12-13 | 2025-03-25 | 江苏宝众宝达药业股份有限公司 | 一种(2r,5r)-1,2,5-三甲基哌嗪的制备方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6326507B1 (en) | 1998-06-19 | 2001-12-04 | Trustees Of Dartmouth College | Therapeutic compounds and methods of use |
| EP2440204B1 (en) * | 2009-06-12 | 2013-12-18 | Bristol-Myers Squibb Company | Nicotinamide compounds useful as kinase modulators |
| US20140256767A1 (en) * | 2011-10-31 | 2014-09-11 | The Broad Institute, Inc. | Direct inhibitors of keap1-nrf2 interaction as antioxidant inflammation modulators |
| US9403774B2 (en) * | 2012-10-12 | 2016-08-02 | Bristol-Myers Squibb Company | Guanidine and amine substituted tetrahydroisoquinoline compounds as factor xia inhibitors |
| AR096046A1 (es) | 2013-04-24 | 2015-12-02 | Abbvie Inc | Derivados de 2,2-difluoropropanamida de metil bardoxolona, formas polimórficas y métodos de uso |
| US10568876B2 (en) * | 2014-09-05 | 2020-02-25 | Merck Sharp & Dohme Corp. | Tetrahydroisoquinoline derivatives useful as inhibitors of diacylglyceride O-acyltransferase 2 |
| EP3250198A1 (en) | 2014-12-04 | 2017-12-06 | Biogen MA Inc. | Multiple sclerosis treatment regimen using dimethyl fumarate |
| US20190389836A1 (en) * | 2017-01-30 | 2019-12-26 | Biogen Ma Inc. | Nrf2 activator |
| CN110294744A (zh) * | 2018-03-21 | 2019-10-01 | 中国医学科学院药物研究所 | Gpr40受体激动剂、其制法和其药物组合物与用途 |
| MX2021004566A (es) * | 2018-10-22 | 2021-06-08 | C4X Discovery Ltd | Compuestos terapeuticos. |
| JP7602469B2 (ja) | 2019-02-15 | 2024-12-18 | グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッド | Ｎｒｆ２活性剤としてのヒドロキシピリドキシアゼピン |
| GB202005852D0 (en) * | 2020-04-22 | 2020-06-03 | C4X Discovery Ltd | Therapeutic compounds |
| GB202005863D0 (en) * | 2020-04-22 | 2020-06-03 | C4X Discovery Ltd | Therapeutic compounds |
| CN114507181B (zh) * | 2020-11-17 | 2024-03-26 | 中国医学科学院药物研究所 | 含5-取代四氢异喹啉的丙酸类化合物、其药物组合物和应用 |
-
2023
- 2023-01-06 PE PE2024001464A patent/PE20241779A1/es unknown
- 2023-01-06 US US18/726,155 patent/US20250084093A1/en active Pending
- 2023-01-06 CA CA3246898A patent/CA3246898A1/en active Pending
- 2023-01-06 EP EP23737317.0A patent/EP4446312A4/en active Pending
- 2023-01-06 TW TW112100509A patent/TW202340204A/zh unknown
- 2023-01-06 AU AU2023204960A patent/AU2023204960A1/en active Pending
- 2023-01-06 CN CN202380015949.6A patent/CN118488944A/zh active Pending
- 2023-01-06 IL IL312793A patent/IL312793A/en unknown
- 2023-01-06 WO PCT/JP2023/000211 patent/WO2023132369A1/ja not_active Ceased
- 2023-01-06 CR CR20240325A patent/CR20240325A/es unknown
- 2023-01-06 KR KR1020247025555A patent/KR20240133727A/ko active Pending
- 2023-01-06 MX MX2024008480A patent/MX2024008480A/es unknown
- 2023-01-06 AR ARP230100035A patent/AR128216A1/es unknown
- 2023-01-06 JP JP2023572495A patent/JP7661533B2/ja active Active
-
2024
- 2024-06-07 CL CL2024001687A patent/CL2024001687A1/es unknown
- 2024-06-19 CO CONC2024/0007707A patent/CO2024007707A2/es unknown
- 2024-08-06 ZA ZA2024/06044A patent/ZA202406044B/en unknown
-
2025
- 2025-01-21 US US19/033,289 patent/US12441735B2/en active Active
- 2025-04-02 JP JP2025061016A patent/JP2025106358A/ja active Pending
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