JP2025106358A5 - - Google Patents

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Publication number
JP2025106358A5
JP2025106358A5 JP2025061016A JP2025061016A JP2025106358A5 JP 2025106358 A5 JP2025106358 A5 JP 2025106358A5 JP 2025061016 A JP2025061016 A JP 2025061016A JP 2025061016 A JP2025061016 A JP 2025061016A JP 2025106358 A5 JP2025106358 A5 JP 2025106358A5
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JP
Japan
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alkyl
group
membered
alkoxy
oxa
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Pending
Application number
JP2025061016A
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English (en)
Japanese (ja)
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JP2025106358A (ja
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Publication date
Priority claimed from PCT/JP2023/000211 external-priority patent/WO2023132369A1/ja
Application filed filed Critical
Publication of JP2025106358A publication Critical patent/JP2025106358A/ja
Publication of JP2025106358A5 publication Critical patent/JP2025106358A5/ja
Pending legal-status Critical Current

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JP2025061016A 2022-01-07 2025-04-02 Ｎｒｆ２活性化作用を有する含窒素複素環化合物 Pending JP2025106358A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2022001804 2022-01-07
JP2022001804 2022-01-07
PCT/JP2023/000211 WO2023132369A1 (ja) 2022-01-07 2023-01-06 Ｎｒｆ２活性化作用を有する含窒素複素環化合物
JP2023572495A JP7661533B2 (ja) 2022-01-07 2023-01-06 Ｎｒｆ２活性化作用を有する含窒素複素環化合物

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2023572495A Division JP7661533B2 (ja) 2022-01-07 2023-01-06 Ｎｒｆ２活性化作用を有する含窒素複素環化合物

Publications (2)

Publication Number Publication Date
JP2025106358A JP2025106358A (ja) 2025-07-15
JP2025106358A5 true JP2025106358A5 (https=) 2026-01-13

Family

ID=87073790

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2023572495A Active JP7661533B2 (ja) 2022-01-07 2023-01-06 Ｎｒｆ２活性化作用を有する含窒素複素環化合物
JP2025061016A Pending JP2025106358A (ja) 2022-01-07 2025-04-02 Ｎｒｆ２活性化作用を有する含窒素複素環化合物

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2023572495A Active JP7661533B2 (ja) 2022-01-07 2023-01-06 Ｎｒｆ２活性化作用を有する含窒素複素環化合物

Country Status (17)

Country Link
US (2) US20250084093A1 (https=)
EP (1) EP4446312A4 (https=)
JP (2) JP7661533B2 (https=)
KR (1) KR20240133727A (https=)
CN (1) CN118488944A (https=)
AR (1) AR128216A1 (https=)
AU (1) AU2023204960A1 (https=)
CA (1) CA3246898A1 (https=)
CL (1) CL2024001687A1 (https=)
CO (1) CO2024007707A2 (https=)
CR (1) CR20240325A (https=)
IL (1) IL312793A (https=)
MX (1) MX2024008480A (https=)
PE (1) PE20241779A1 (https=)
TW (1) TW202340204A (https=)
WO (1) WO2023132369A1 (https=)
ZA (1) ZA202406044B (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024262491A1 (ja) * 2023-06-19 2024-12-26 中外製薬株式会社 Ｎｒｆ２活性化作用を有する含窒素複素環化合物の結晶
CN118221551A (zh) * 2024-04-10 2024-06-21 南京艾康生物科技有限公司 4-甲酰苄基氨基甲酸叔丁酯的制备方法
CN119684220A (zh) * 2024-12-13 2025-03-25 江苏宝众宝达药业股份有限公司 一种(2r,5r)-1,2,5-三甲基哌嗪的制备方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6326507B1 (en) 1998-06-19 2001-12-04 Trustees Of Dartmouth College Therapeutic compounds and methods of use
EP2440204B1 (en) * 2009-06-12 2013-12-18 Bristol-Myers Squibb Company Nicotinamide compounds useful as kinase modulators
US20140256767A1 (en) * 2011-10-31 2014-09-11 The Broad Institute, Inc. Direct inhibitors of keap1-nrf2 interaction as antioxidant inflammation modulators
US9403774B2 (en) * 2012-10-12 2016-08-02 Bristol-Myers Squibb Company Guanidine and amine substituted tetrahydroisoquinoline compounds as factor xia inhibitors
AR096046A1 (es) 2013-04-24 2015-12-02 Abbvie Inc Derivados de 2,2-difluoropropanamida de metil bardoxolona, formas polimórficas y métodos de uso
US10568876B2 (en) * 2014-09-05 2020-02-25 Merck Sharp & Dohme Corp. Tetrahydroisoquinoline derivatives useful as inhibitors of diacylglyceride O-acyltransferase 2
EP3250198A1 (en) 2014-12-04 2017-12-06 Biogen MA Inc. Multiple sclerosis treatment regimen using dimethyl fumarate
US20190389836A1 (en) * 2017-01-30 2019-12-26 Biogen Ma Inc. Nrf2 activator
CN110294744A (zh) * 2018-03-21 2019-10-01 中国医学科学院药物研究所 Gpr40受体激动剂、其制法和其药物组合物与用途
MX2021004566A (es) * 2018-10-22 2021-06-08 C4X Discovery Ltd Compuestos terapeuticos.
JP7602469B2 (ja) 2019-02-15 2024-12-18 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッド Ｎｒｆ２活性剤としてのヒドロキシピリドキシアゼピン
GB202005852D0 (en) * 2020-04-22 2020-06-03 C4X Discovery Ltd Therapeutic compounds
GB202005863D0 (en) * 2020-04-22 2020-06-03 C4X Discovery Ltd Therapeutic compounds
CN114507181B (zh) * 2020-11-17 2024-03-26 中国医学科学院药物研究所 含5-取代四氢异喹啉的丙酸类化合物、其药物组合物和应用

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