JPWO2023083900A5 - - Google Patents
Info
- Publication number
- JPWO2023083900A5 JPWO2023083900A5 JP2024549576A JP2024549576A JPWO2023083900A5 JP WO2023083900 A5 JPWO2023083900 A5 JP WO2023083900A5 JP 2024549576 A JP2024549576 A JP 2024549576A JP 2024549576 A JP2024549576 A JP 2024549576A JP WO2023083900 A5 JPWO2023083900 A5 JP WO2023083900A5
- Authority
- JP
- Japan
- Prior art keywords
- conjugate
- optionally substituted
- alkyl
- aromatic residue
- substituted aromatic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP21207195 | 2021-11-09 | ||
| EP21207195.5 | 2021-11-09 | ||
| PCT/EP2022/081345 WO2023083900A1 (en) | 2021-11-09 | 2022-11-09 | Conjugates comprising a phosphorus (v) and a drug moiety |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024540691A JP2024540691A (ja) | 2024-10-31 |
| JPWO2023083900A5 true JPWO2023083900A5 (https=) | 2025-11-17 |
| JP2024540691A5 JP2024540691A5 (https=) | 2025-11-17 |
Family
ID=78592631
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024549576A Pending JP2024540691A (ja) | 2021-11-09 | 2022-11-09 | リン（ｖ）および薬物部分を含むコンジュゲート |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US20230330258A1 (https=) |
| EP (1) | EP4429708A1 (https=) |
| JP (1) | JP2024540691A (https=) |
| KR (1) | KR20240100413A (https=) |
| CN (1) | CN118302197A (https=) |
| AU (1) | AU2022385379A1 (https=) |
| CA (1) | CA3237371A1 (https=) |
| CL (1) | CL2024001372A1 (https=) |
| CO (1) | CO2024005877A2 (https=) |
| DE (1) | DE22817174T1 (https=) |
| ES (1) | ES2999335T1 (https=) |
| IL (1) | IL312675A (https=) |
| MX (1) | MX2024005546A (https=) |
| PE (1) | PE20242107A1 (https=) |
| WO (1) | WO2023083900A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024133845A1 (en) * | 2022-12-22 | 2024-06-27 | Tubulis Gmbh | Conjugates comprising a phosphorus(v) moiety and a drug |
| WO2025027529A1 (en) | 2023-07-31 | 2025-02-06 | Advesya | Anti-il-1rap antibody drug conjugates and methods of use thereof |
| WO2025046090A1 (en) | 2023-09-01 | 2025-03-06 | Tubulis Gmbh | Methods of preparing phosphonamidate compounds |
| TW202530255A (zh) | 2023-12-15 | 2025-08-01 | 法商亞維西亞有限公司 | 抗ｉｌ－１ｒａｐ結合結構域及其抗體－藥物偶聯物 |
| WO2025149667A1 (en) | 2024-01-12 | 2025-07-17 | Pheon Therapeutics Ltd | Antibody drug conjugates and uses thereof |
| EP4658320A1 (en) | 2024-02-27 | 2025-12-10 | Bristol-Myers Squibb Company | Anti-ceacam5 antibody drug conjugates |
| WO2025262641A1 (en) | 2024-06-19 | 2025-12-26 | Pheon Therapeutics Ltd | Antibody drug conjugates that bind cdcp1 and uses thereof |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US633410A (en) | 1898-09-22 | 1899-09-19 | George A Ames | Ice-cutter. |
| EP0401384B1 (en) | 1988-12-22 | 1996-03-13 | Kirin-Amgen, Inc. | Chemically modified granulocyte colony stimulating factor |
| US5208020A (en) | 1989-10-25 | 1993-05-04 | Immunogen Inc. | Cytotoxic agents comprising maytansinoids and their therapeutic use |
| JP2763020B2 (ja) | 1995-04-27 | 1998-06-11 | 日本電気株式会社 | 半導体パッケージ及び半導体装置 |
| US5672662A (en) | 1995-07-07 | 1997-09-30 | Shearwater Polymers, Inc. | Poly(ethylene glycol) and related polymers monosubstituted with propionic or butanoic acids and functional derivatives thereof for biotechnical applications |
| AU725609C (en) | 1995-08-18 | 2002-01-03 | Morphosys Ag | Protein/(poly)peptide libraries |
| EP1731174A3 (en) | 1996-08-02 | 2007-01-17 | Ortho-McNeil Pharmaceutical, Inc. | Polypeptides having a covalently bound N-terminal polyethylene glycol via hydrazone or oxime bond |
| SI1545613T1 (sl) | 2002-07-31 | 2011-11-30 | Seattle Genetics Inc | Avristatinski konjugati in njihova uporaba za zdravljenje raka avtoimunske bolezni ali infekcijskebolezni |
| KR20200058590A (ko) | 2008-04-30 | 2020-05-27 | 이뮤노젠 아이엔씨 | 가교제 및 그 용도 |
| ES2826398T3 (es) | 2013-10-15 | 2021-05-18 | Seagen Inc | Enlazadores-fármacos pegilados para una mejor farmacocinética de los conjugados ligando-fármaco |
| AU2017320913B2 (en) | 2016-09-01 | 2024-08-15 | Forschungsverbund Berlin E.V. | Chemoselective thiol-conjugation with alkene or alkyne-phosphonamidates |
| JP7429191B2 (ja) | 2018-03-07 | 2024-02-07 | フォルシュングスフェアバント ベルリン エー．ベー． | アルケンホスホノチオレートまたはアルキンホスホノチオレートおよびアルケンホスホネートまたはアルキンホスホネートとの化学選択的チオールコンジュゲーション |
| TWI851577B (zh) | 2018-06-07 | 2024-08-11 | 美商思進公司 | 喜樹鹼結合物 |
-
2022
- 2022-11-09 CN CN202280074835.4A patent/CN118302197A/zh active Pending
- 2022-11-09 CA CA3237371A patent/CA3237371A1/en active Pending
- 2022-11-09 PE PE2024001005A patent/PE20242107A1/es unknown
- 2022-11-09 IL IL312675A patent/IL312675A/en unknown
- 2022-11-09 MX MX2024005546A patent/MX2024005546A/es unknown
- 2022-11-09 DE DE22817174.0T patent/DE22817174T1/de active Pending
- 2022-11-09 WO PCT/EP2022/081345 patent/WO2023083900A1/en not_active Ceased
- 2022-11-09 US US18/054,018 patent/US20230330258A1/en not_active Abandoned
- 2022-11-09 KR KR1020247019065A patent/KR20240100413A/ko active Pending
- 2022-11-09 EP EP22817174.0A patent/EP4429708A1/en active Pending
- 2022-11-09 AU AU2022385379A patent/AU2022385379A1/en active Pending
- 2022-11-09 JP JP2024549576A patent/JP2024540691A/ja active Pending
- 2022-11-09 ES ES22817174T patent/ES2999335T1/es active Pending
-
2024
- 2024-05-06 CO CONC2024/0005877A patent/CO2024005877A2/es unknown
- 2024-05-06 CL CL2024001372A patent/CL2024001372A1/es unknown
-
2025
- 2025-05-14 US US19/207,970 patent/US20250281634A1/en active Pending
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