JPWO2023054671A5 - - Google Patents
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- Publication number
- JPWO2023054671A5 JPWO2023054671A5 JP2023551895A JP2023551895A JPWO2023054671A5 JP WO2023054671 A5 JPWO2023054671 A5 JP WO2023054671A5 JP 2023551895 A JP2023551895 A JP 2023551895A JP 2023551895 A JP2023551895 A JP 2023551895A JP WO2023054671 A5 JPWO2023054671 A5 JP WO2023054671A5
- Authority
- JP
- Japan
- Prior art keywords
- gene
- e4orf6
- sequence
- cell
- promoter
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108090000623 proteins and genes Proteins 0.000 claims 30
- 108010076504 Protein Sorting Signals Proteins 0.000 claims 12
- 241000702421 Dependoparvovirus Species 0.000 claims 9
- 238000004519 manufacturing process Methods 0.000 claims 9
- 108700028146 Genetic Enhancer Elements Proteins 0.000 claims 7
- 241000701022 Cytomegalovirus Species 0.000 claims 6
- 101000666382 Homo sapiens Transcription factor E2-alpha Proteins 0.000 claims 6
- 108091034131 VA RNA Proteins 0.000 claims 6
- 101150044789 Cap gene Proteins 0.000 claims 5
- 230000003449 preventive effect Effects 0.000 claims 5
- 101150066583 rep gene Proteins 0.000 claims 5
- 230000001225 therapeutic effect Effects 0.000 claims 5
- 239000003623 enhancer Substances 0.000 claims 3
- 230000002103 transcriptional effect Effects 0.000 claims 3
- 239000013604 expression vector Substances 0.000 claims 2
- 108020004999 messenger RNA Proteins 0.000 claims 1
- 239000013600 plasmid vector Substances 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021160729 | 2021-09-30 | ||
| PCT/JP2022/036684 WO2023054671A1 (ja) | 2021-09-30 | 2022-09-30 | アデノ随伴ウイルスの製造方法、細胞および発現ベクター |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2023054671A1 JPWO2023054671A1 (https=) | 2023-04-06 |
| JPWO2023054671A5 true JPWO2023054671A5 (https=) | 2024-06-24 |
Family
ID=85782983
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023551895A Pending JPWO2023054671A1 (https=) | 2021-09-30 | 2022-09-30 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20240263149A1 (https=) |
| EP (1) | EP4410971A4 (https=) |
| JP (1) | JPWO2023054671A1 (https=) |
| CN (1) | CN118119703A (https=) |
| WO (1) | WO2023054671A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN120574787B (zh) * | 2025-08-01 | 2025-11-18 | 华中科技大学同济医学院附属协和医院 | 一种腺相关病毒及其在促动静脉内瘘成熟中的应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6281010B1 (en) * | 1995-06-05 | 2001-08-28 | The Trustees Of The University Of Pennsylvania | Adenovirus gene therapy vehicle and cell line |
| JP2006075171A (ja) * | 1995-11-09 | 2006-03-23 | Avigen Inc | 組換えａａｖビリオン産生における使用のための補助機能 |
| JP5584393B2 (ja) * | 2004-12-31 | 2014-09-03 | ホルム，ペル・ゾンネ | 動物細胞における多剤耐性を逆転させる方法 |
| EP3039129B1 (en) | 2013-08-30 | 2018-06-27 | Amgen Inc. | High titer recombinant aav vector production in adherent and suspension cells |
| WO2018150271A1 (en) | 2017-02-17 | 2018-08-23 | Lonza Ltd. | Mammalian cells for producing adeno-associated viruses |
| SG11202106217TA (en) * | 2018-12-21 | 2021-07-29 | Lonza Walkersville Inc | Adeno-associated virus (aav) producer cell line and related methods |
| AU2020272557A1 (en) * | 2019-04-12 | 2021-12-09 | Ascend Gene And Cell Therapies Ltd | Plasmid system |
| WO2020235543A1 (ja) | 2019-05-20 | 2020-11-26 | Ｊｃｒファーマ株式会社 | 組換えａａｖビリオンの製造に用いる核酸分子 |
-
2022
- 2022-09-30 EP EP22876533.5A patent/EP4410971A4/en active Pending
- 2022-09-30 WO PCT/JP2022/036684 patent/WO2023054671A1/ja not_active Ceased
- 2022-09-30 CN CN202280066251.2A patent/CN118119703A/zh active Pending
- 2022-09-30 JP JP2023551895A patent/JPWO2023054671A1/ja active Pending
-
2024
- 2024-03-29 US US18/621,693 patent/US20240263149A1/en active Pending
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