CN118119703A - 腺相关病毒的制造方法、细胞及表达载体 - Google Patents
腺相关病毒的制造方法、细胞及表达载体 Download PDFInfo
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- CN118119703A CN118119703A CN202280066251.2A CN202280066251A CN118119703A CN 118119703 A CN118119703 A CN 118119703A CN 202280066251 A CN202280066251 A CN 202280066251A CN 118119703 A CN118119703 A CN 118119703A
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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- C12N15/09—Recombinant DNA-technology
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- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
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- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14151—Methods of production or purification of viral material
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- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14151—Methods of production or purification of viral material
- C12N2750/14152—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
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- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
- C12N2830/002—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
- C12N2830/003—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor tet inducible
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- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/15—Vector systems having a special element relevant for transcription chimeric enhancer/promoter combination
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- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/50—Vector systems having a special element relevant for transcription regulating RNA stability, not being an intron, e.g. poly A signal
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- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
- C12N2840/203—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES
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- Life Sciences & Earth Sciences (AREA)
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021-160729 | 2021-09-30 | ||
| JP2021160729 | 2021-09-30 | ||
| PCT/JP2022/036684 WO2023054671A1 (ja) | 2021-09-30 | 2022-09-30 | アデノ随伴ウイルスの製造方法、細胞および発現ベクター |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN118119703A true CN118119703A (zh) | 2024-05-31 |
Family
ID=85782983
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202280066251.2A Pending CN118119703A (zh) | 2021-09-30 | 2022-09-30 | 腺相关病毒的制造方法、细胞及表达载体 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20240263149A1 (https=) |
| EP (1) | EP4410971A4 (https=) |
| JP (1) | JPWO2023054671A1 (https=) |
| CN (1) | CN118119703A (https=) |
| WO (1) | WO2023054671A1 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN120574787A (zh) * | 2025-08-01 | 2025-09-02 | 华中科技大学同济医学院附属协和医院 | 一种腺相关病毒及其在促动静脉内瘘成熟中的应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6281010B1 (en) * | 1995-06-05 | 2001-08-28 | The Trustees Of The University Of Pennsylvania | Adenovirus gene therapy vehicle and cell line |
| JP2006075171A (ja) * | 1995-11-09 | 2006-03-23 | Avigen Inc | 組換えaavビリオン産生における使用のための補助機能 |
| JP5584393B2 (ja) * | 2004-12-31 | 2014-09-03 | ホルム,ペル・ゾンネ | 動物細胞における多剤耐性を逆転させる方法 |
| EP3039129B1 (en) | 2013-08-30 | 2018-06-27 | Amgen Inc. | High titer recombinant aav vector production in adherent and suspension cells |
| WO2018150271A1 (en) | 2017-02-17 | 2018-08-23 | Lonza Ltd. | Mammalian cells for producing adeno-associated viruses |
| SG11202106217TA (en) * | 2018-12-21 | 2021-07-29 | Lonza Walkersville Inc | Adeno-associated virus (aav) producer cell line and related methods |
| AU2020272557A1 (en) * | 2019-04-12 | 2021-12-09 | Ascend Gene And Cell Therapies Ltd | Plasmid system |
| WO2020235543A1 (ja) | 2019-05-20 | 2020-11-26 | Jcrファーマ株式会社 | 組換えaavビリオンの製造に用いる核酸分子 |
-
2022
- 2022-09-30 EP EP22876533.5A patent/EP4410971A4/en active Pending
- 2022-09-30 WO PCT/JP2022/036684 patent/WO2023054671A1/ja not_active Ceased
- 2022-09-30 CN CN202280066251.2A patent/CN118119703A/zh active Pending
- 2022-09-30 JP JP2023551895A patent/JPWO2023054671A1/ja active Pending
-
2024
- 2024-03-29 US US18/621,693 patent/US20240263149A1/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN120574787A (zh) * | 2025-08-01 | 2025-09-02 | 华中科技大学同济医学院附属协和医院 | 一种腺相关病毒及其在促动静脉内瘘成熟中的应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPWO2023054671A1 (https=) | 2023-04-06 |
| WO2023054671A1 (ja) | 2023-04-06 |
| EP4410971A4 (en) | 2025-06-04 |
| US20240263149A1 (en) | 2024-08-08 |
| EP4410971A1 (en) | 2024-08-07 |
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