JPWO2023054350A5 - - Google Patents
Download PDFInfo
- Publication number
- JPWO2023054350A5 JPWO2023054350A5 JP2023551520A JP2023551520A JPWO2023054350A5 JP WO2023054350 A5 JPWO2023054350 A5 JP WO2023054350A5 JP 2023551520 A JP2023551520 A JP 2023551520A JP 2023551520 A JP2023551520 A JP 2023551520A JP WO2023054350 A5 JPWO2023054350 A5 JP WO2023054350A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- dichloroacetic
- formula
- nucleic acid
- acid molecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021158346 | 2021-09-28 | ||
| PCT/JP2022/035920 WO2023054350A1 (ja) | 2021-09-28 | 2022-09-27 | 精製ジクロロ酢酸の製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2023054350A1 JPWO2023054350A1 (https=) | 2023-04-06 |
| JPWO2023054350A5 true JPWO2023054350A5 (https=) | 2025-06-11 |
Family
ID=85782759
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023551520A Pending JPWO2023054350A1 (https=) | 2021-09-28 | 2022-09-27 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20250051256A1 (https=) |
| EP (1) | EP4410770A4 (https=) |
| JP (1) | JPWO2023054350A1 (https=) |
| KR (1) | KR20240082343A (https=) |
| CN (1) | CN117980285A (https=) |
| WO (1) | WO2023054350A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2026071145A1 (ja) * | 2024-09-30 | 2026-04-02 | 住友化学株式会社 | 核酸オリゴマーの製造方法 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5058014A (https=) * | 1973-09-20 | 1975-05-20 | ||
| RU2098401C1 (ru) * | 1995-12-19 | 1997-12-10 | Акционерное общество открытого типа "Кирово-Чепецкий химический комбинат им.Б.П.Константинова" | Способ выделения дихлоруксусной кислоты |
| US7273933B1 (en) * | 1998-02-26 | 2007-09-25 | Isis Pharmaceuticals, Inc. | Methods for synthesis of oligonucleotides |
| US6077709A (en) | 1998-09-29 | 2000-06-20 | Isis Pharmaceuticals Inc. | Antisense modulation of Survivin expression |
| US6887990B1 (en) | 1999-02-05 | 2005-05-03 | Amersham Biosciences Corp | Method for deprotecting oligonucleotides |
| US6261840B1 (en) | 2000-01-18 | 2001-07-17 | Isis Pharmaceuticals, Inc. | Antisense modulation of PTP1B expression |
| AU2005275801B2 (en) | 2004-08-26 | 2012-05-10 | Nippon Shinyaku Co., Ltd. | Phosphoramidite compound and method for producing oligo-RNA |
| ES2526295T5 (es) | 2006-10-18 | 2021-05-04 | Ionis Pharmaceuticals Inc | Compuestos antisentido |
| EP2933333B1 (en) | 2010-07-08 | 2018-02-21 | Bonac Corporation | Single-strand nucleic acid molecule for controlling gene expression |
| EP2639307B1 (en) | 2010-08-03 | 2015-03-04 | Bonac Corporation | Single-stranded nucleic acid molecule having nitrogen-containing alicyclic skeleton |
| MX351566B (es) * | 2011-06-21 | 2017-10-19 | Akzo Nobel Chemicals Int Bv | Proceso para separar acido monocloroacetico y acido dicloroacetico mediante destilacion extractiva. |
| MX370398B (es) | 2011-08-25 | 2019-12-11 | Bonac Corp | Compuesto de glicosido, metodo para producir tioeter, eter, metodo para producir eter, metodo para producir un compuesto de glicosido, metodo para producir acido nucleico. |
| IN2014DN09074A (https=) * | 2012-04-06 | 2015-05-22 | Akzo Nobel Chemicals Int Bv | |
| AU2013266968B2 (en) | 2012-05-25 | 2017-06-29 | Emmanuelle CHARPENTIER | Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription |
| CA2969619A1 (en) | 2014-12-03 | 2016-06-09 | Agilent Technologies, Inc. | Guide rna with chemical modifications |
| JPWO2018182008A1 (ja) | 2017-03-31 | 2020-02-06 | 株式会社ボナック | 遺伝子発現制御機能を有する環状型核酸分子 |
| BR112020005230A2 (pt) | 2017-09-19 | 2020-09-24 | Alnylam Pharmaceuticals, Inc. | composições e métodos para o tratamento da amiloidose mediada por transtiretina (ttr) |
| US20210188895A1 (en) | 2017-10-13 | 2021-06-24 | Bonac Corporation | Single-stranded nucleic acid molecule, and production method therefor |
| KR102670605B1 (ko) | 2018-04-24 | 2024-05-29 | 스미또모 가가꾸 가부시끼가이샤 | 아미다이트 화합물 및 그 화합물을 사용한 폴리뉴클레오티드의 제조 방법 |
| EP4130018A4 (en) * | 2020-03-27 | 2024-04-17 | Sumitomo Chemical Company, Limited | METHOD FOR PRODUCING A NUCLEIC ACID OLIGOMER |
| JP7655001B2 (ja) | 2020-03-27 | 2025-04-02 | 株式会社プロテリアル | 巻磁心の製造方法、及び巻磁心 |
| CN115867559A (zh) * | 2020-07-09 | 2023-03-28 | 住友化学株式会社 | 核酸寡聚物的制造方法 |
| CN112209817A (zh) * | 2020-10-20 | 2021-01-12 | 湖南恒光科技股份有限公司 | 一种二氯乙酸连续氯化工艺系统及方法 |
-
2022
- 2022-09-27 CN CN202280064530.5A patent/CN117980285A/zh active Pending
- 2022-09-27 WO PCT/JP2022/035920 patent/WO2023054350A1/ja not_active Ceased
- 2022-09-27 US US18/691,479 patent/US20250051256A1/en active Pending
- 2022-09-27 EP EP22876216.7A patent/EP4410770A4/en active Pending
- 2022-09-27 KR KR1020247010581A patent/KR20240082343A/ko active Pending
- 2022-09-27 JP JP2023551520A patent/JPWO2023054350A1/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP3081882B2 (ja) | 還元によるヒドロキシル保護基の直交除去及びオリゴヌクレオチドの化学合成におけるそれらの利用 | |
| EP1510523A1 (en) | Precurors for two-step polynucleotide synthesis | |
| WO2005070859A1 (ja) | フルオラス担体およびそれを用いたオリゴヌクレオチド誘導体の製造方法 | |
| HUT64555A (en) | A method for linking nucleosides with syloxane bridge | |
| JPH07500576A (ja) | オリゴヌクレオチドの５’末端へ官能基を提供するための修飾された亜リン酸中間体 | |
| CN112424213A (zh) | 寡核苷酸合成用片段及其制造方法、以及使用其的寡核苷酸的合成方法 | |
| JPWO2023054350A5 (https=) | ||
| EP0607337B1 (fr) | Procede de synthese d'acide ribonucleique (arn) utilisant un nouveau reactif de deprotection | |
| EP1317466B1 (en) | Synthons for oligonucleotide synthesis | |
| JP7698631B2 (ja) | 核酸オリゴマーの製造方法 | |
| JP7759323B2 (ja) | 核酸オリゴマーの製造方法 | |
| JP6537338B2 (ja) | 核酸固相合成用リンカー及び担体 | |
| WO2025044766A1 (zh) | 二氧化硅微球在合成超长寡核苷酸中的应用以及合成超长寡核苷酸的方法 | |
| US20250051256A1 (en) | Production method for purified dichloroacetic acid | |
| JP2023514503A5 (https=) | ||
| US20260001902A1 (en) | Improved oligonucleotide synthesis | |
| CN1900103A (zh) | 用于rna寡核苷酸合成中的核苷亚磷酰胺及其合成方法 | |
| JPWO2024089953A5 (https=) | ||
| KR20250042734A (ko) | 올리고뉴클레오티드의 제조 방법 | |
| WO2024024873A1 (ja) | チオ化溶液 | |
| JP5956108B2 (ja) | １，３，５−トリメチルヘキサヒドロ−１，３，５−トリアジンを含有しないｎ−メチルイミダゾールのキャッピング剤を用いたオリゴヌクレオチドまたはホスホロチオ酸オリゴヌクレオチドの合成 | |
| JP7825064B2 (ja) | オリゴヌクレオチドの製造方法 | |
| JP3485024B2 (ja) | ヌクレオチド化合物 | |
| CN120418262A (zh) | 寡核苷酸的制造方法 | |
| RU2440364C2 (ru) | Синтез фосфитилированных соединений с использованием четвертичного гетероциклического активатора |