JPWO2024089953A5 - - Google Patents
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- JPWO2024089953A5 JPWO2024089953A5 JP2024552830A JP2024552830A JPWO2024089953A5 JP WO2024089953 A5 JPWO2024089953 A5 JP WO2024089953A5 JP 2024552830 A JP2024552830 A JP 2024552830A JP 2024552830 A JP2024552830 A JP 2024552830A JP WO2024089953 A5 JPWO2024089953 A5 JP WO2024089953A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- oligonucleotide
- acid
- formula
- represented
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022172158 | 2022-10-27 | ||
| JP2022172158 | 2022-10-27 | ||
| PCT/JP2023/026108 WO2024089953A1 (ja) | 2022-10-27 | 2023-07-14 | オリゴヌクレオチドの製造方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPWO2024089953A1 JPWO2024089953A1 (https=) | 2024-05-02 |
| JPWO2024089953A5 true JPWO2024089953A5 (https=) | 2025-01-08 |
| JP7825064B2 JP7825064B2 (ja) | 2026-03-05 |
Family
ID=90830457
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024552830A Active JP7825064B2 (ja) | 2022-10-27 | 2023-07-14 | オリゴヌクレオチドの製造方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20250136632A1 (https=) |
| EP (1) | EP4477659A4 (https=) |
| JP (1) | JP7825064B2 (https=) |
| KR (1) | KR20250092173A (https=) |
| CN (1) | CN119948043A (https=) |
| WO (1) | WO2024089953A1 (https=) |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5510476A (en) | 1994-07-07 | 1996-04-23 | Isis Pharmaceuticals, Inc. | Carbocation scavenging during oligonucleotide synthesis |
| US6077709A (en) | 1998-09-29 | 2000-06-20 | Isis Pharmaceuticals Inc. | Antisense modulation of Survivin expression |
| US6887990B1 (en) | 1999-02-05 | 2005-05-03 | Amersham Biosciences Corp | Method for deprotecting oligonucleotides |
| US6261840B1 (en) | 2000-01-18 | 2001-07-17 | Isis Pharmaceuticals, Inc. | Antisense modulation of PTP1B expression |
| AU2003216830A1 (en) * | 2002-03-21 | 2003-10-08 | Avecia Biotechnology Inc. | Purification methods for oligonucleotides and their analogs |
| AU2005275801B2 (en) | 2004-08-26 | 2012-05-10 | Nippon Shinyaku Co., Ltd. | Phosphoramidite compound and method for producing oligo-RNA |
| ES2526295T5 (es) | 2006-10-18 | 2021-05-04 | Ionis Pharmaceuticals Inc | Compuestos antisentido |
| EP2933333B1 (en) | 2010-07-08 | 2018-02-21 | Bonac Corporation | Single-strand nucleic acid molecule for controlling gene expression |
| DK2711370T3 (en) | 2011-05-17 | 2018-02-26 | Ajinomoto Kk | PROCEDURE FOR THE PREPARATION OF OLIGONUCLEOTIDES |
| MX370398B (es) * | 2011-08-25 | 2019-12-11 | Bonac Corp | Compuesto de glicosido, metodo para producir tioeter, eter, metodo para producir eter, metodo para producir un compuesto de glicosido, metodo para producir acido nucleico. |
| AU2013266968B2 (en) | 2012-05-25 | 2017-06-29 | Emmanuelle CHARPENTIER | Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription |
| RU2736728C2 (ru) | 2014-10-17 | 2020-11-19 | Иллумина Кембридж Лимитед | Транспозиция с сохранением сцепления генов |
| CA2969619A1 (en) | 2014-12-03 | 2016-06-09 | Agilent Technologies, Inc. | Guide rna with chemical modifications |
| US10072261B1 (en) * | 2016-03-25 | 2018-09-11 | Agilent Technologies, Inc. | Double coupling method for oligonucleotide synthesis |
| US20210309690A1 (en) * | 2016-07-27 | 2021-10-07 | Roche Innovation Center Copenhagen A/S | Oligonucleotide synthesis |
| JPWO2018182008A1 (ja) | 2017-03-31 | 2020-02-06 | 株式会社ボナック | 遺伝子発現制御機能を有する環状型核酸分子 |
| BR112020005230A2 (pt) | 2017-09-19 | 2020-09-24 | Alnylam Pharmaceuticals, Inc. | composições e métodos para o tratamento da amiloidose mediada por transtiretina (ttr) |
| US20210188895A1 (en) | 2017-10-13 | 2021-06-24 | Bonac Corporation | Single-stranded nucleic acid molecule, and production method therefor |
| KR102670605B1 (ko) | 2018-04-24 | 2024-05-29 | 스미또모 가가꾸 가부시끼가이샤 | 아미다이트 화합물 및 그 화합물을 사용한 폴리뉴클레오티드의 제조 방법 |
| CN119143828A (zh) * | 2019-05-08 | 2024-12-17 | 渤健马萨诸塞州股份有限公司 | 寡核苷酸的汇聚液相合成 |
| KR20230106665A (ko) | 2020-11-11 | 2023-07-13 | 바이오젠 엠에이 인코포레이티드 | 올리고뉴클레오티드, 시약, 및 그의 제조 방법 |
| EP4293035A4 (en) * | 2021-02-12 | 2025-03-05 | Ajinomoto Co., Inc. | METHOD FOR THE PRODUCTION OF OLIGONUCLEOTIDES |
-
2023
- 2023-07-14 WO PCT/JP2023/026108 patent/WO2024089953A1/ja not_active Ceased
- 2023-07-14 EP EP23882170.6A patent/EP4477659A4/en active Pending
- 2023-07-14 US US18/858,394 patent/US20250136632A1/en active Pending
- 2023-07-14 KR KR1020257010625A patent/KR20250092173A/ko active Pending
- 2023-07-14 CN CN202380064746.6A patent/CN119948043A/zh active Pending
- 2023-07-14 JP JP2024552830A patent/JP7825064B2/ja active Active
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