JPWO2023022187A5 - - Google Patents
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- Publication number
- JPWO2023022187A5 JPWO2023022187A5 JP2023542437A JP2023542437A JPWO2023022187A5 JP WO2023022187 A5 JPWO2023022187 A5 JP WO2023022187A5 JP 2023542437 A JP2023542437 A JP 2023542437A JP 2023542437 A JP2023542437 A JP 2023542437A JP WO2023022187 A5 JPWO2023022187 A5 JP WO2023022187A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- fluorescent compound
- compound according
- dye
- biological material
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000007850 fluorescent dye Substances 0.000 claims 12
- 239000000975 dye Substances 0.000 claims 10
- 239000012620 biological material Substances 0.000 claims 9
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 8
- 125000000217 alkyl group Chemical group 0.000 claims 7
- 125000003118 aryl group Chemical group 0.000 claims 5
- 150000001875 compounds Chemical class 0.000 claims 5
- OVTCUIZCVUGJHS-UHFFFAOYSA-N dipyrrin Chemical compound C=1C=CNC=1C=C1C=CC=N1 OVTCUIZCVUGJHS-UHFFFAOYSA-N 0.000 claims 4
- 125000001424 substituent group Chemical group 0.000 claims 4
- ZOXJGFHDIHLPTG-UHFFFAOYSA-N Boron Chemical compound [B] ZOXJGFHDIHLPTG-UHFFFAOYSA-N 0.000 claims 3
- 229910052796 boron Inorganic materials 0.000 claims 3
- 125000003545 alkoxy group Chemical group 0.000 claims 2
- IVRMZWNICZWHMI-UHFFFAOYSA-N azide group Chemical group [N-]=[N+]=[N-] IVRMZWNICZWHMI-UHFFFAOYSA-N 0.000 claims 2
- ZYGHJZDHTFUPRJ-UHFFFAOYSA-N coumarin Chemical compound C1=CC=C2OC(=O)C=CC2=C1 ZYGHJZDHTFUPRJ-UHFFFAOYSA-N 0.000 claims 2
- 125000005677 ethinylene group Chemical group [*:2]C#C[*:1] 0.000 claims 2
- 125000001072 heteroaryl group Chemical group 0.000 claims 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 2
- 150000002632 lipids Chemical class 0.000 claims 2
- BBEAQIROQSPTKN-UHFFFAOYSA-N pyrene Chemical compound C1=CC=C2C=CC3=CC=CC4=CC=C1C2=C43 BBEAQIROQSPTKN-UHFFFAOYSA-N 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- -1 -C≡CR b Chemical group 0.000 claims 1
- 239000000232 Lipid Bilayer Substances 0.000 claims 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical group [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 125000003277 amino group Chemical group 0.000 claims 1
- 125000004104 aryloxy group Chemical group 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 238000012650 click reaction Methods 0.000 claims 1
- 229960000956 coumarin Drugs 0.000 claims 1
- 235000001671 coumarin Nutrition 0.000 claims 1
- 125000004093 cyano group Chemical group *C#N 0.000 claims 1
- GVEPBJHOBDJJJI-UHFFFAOYSA-N fluoranthrene Natural products C1=CC(C2=CC=CC=C22)=C3C2=CC=CC3=C1 GVEPBJHOBDJJJI-UHFFFAOYSA-N 0.000 claims 1
- 125000005843 halogen group Chemical group 0.000 claims 1
- 125000005553 heteroaryloxy group Chemical group 0.000 claims 1
- GPRLSGONYQIRFK-UHFFFAOYSA-N hydron Chemical compound [H+] GPRLSGONYQIRFK-UHFFFAOYSA-N 0.000 claims 1
- 230000003993 interaction Effects 0.000 claims 1
- 125000005439 maleimidyl group Chemical group C1(C=CC(N1*)=O)=O 0.000 claims 1
- 229910021645 metal ion Inorganic materials 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- NMHMNPHRMNGLLB-UHFFFAOYSA-N phloretic acid Chemical compound OC(=O)CCC1=CC=C(O)C=C1 NMHMNPHRMNGLLB-UHFFFAOYSA-N 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- RQGPLDBZHMVWCH-UHFFFAOYSA-N pyrrolo[3,2-b]pyrrole Chemical compound C1=NC2=CC=NC2=C1 RQGPLDBZHMVWCH-UHFFFAOYSA-N 0.000 claims 1
- 125000003396 thiol group Chemical group [H]S* 0.000 claims 1
- ANRHNWWPFJCPAZ-UHFFFAOYSA-M thionine Chemical compound [Cl-].C1=CC(N)=CC2=[S+]C3=CC(N)=CC=C3N=C21 ANRHNWWPFJCPAZ-UHFFFAOYSA-M 0.000 claims 1
- 125000001425 triazolyl group Chemical group 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021133510 | 2021-08-18 | ||
| PCT/JP2022/031169 WO2023022187A1 (ja) | 2021-08-18 | 2022-08-18 | 蛍光性化合物及びこれを用いた蛍光標識生体物質 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2023022187A1 JPWO2023022187A1 (https=) | 2023-02-23 |
| JPWO2023022187A5 true JPWO2023022187A5 (https=) | 2024-05-15 |
Family
ID=85239876
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023542437A Pending JPWO2023022187A1 (https=) | 2021-08-18 | 2022-08-18 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20240110918A1 (https=) |
| EP (1) | EP4389755A4 (https=) |
| JP (1) | JPWO2023022187A1 (https=) |
| CN (1) | CN117460790B (https=) |
| WO (1) | WO2023022187A1 (https=) |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3912046B4 (de) * | 1988-09-02 | 2004-03-25 | Carnegie Mellon University | Verfahren zum Markieren einer Komponente einer wäßrigen Flüssigkeit und lumineszenzphotostabiles Reaktionsprodukt |
| EP0626016B1 (en) * | 1992-02-10 | 1998-06-03 | Btg International Limited | Chemiluminescent enhancers |
| EP1322710B2 (en) | 2000-09-29 | 2015-02-18 | Life Technologies Corporation | Modified carbocyanine dyes and their conjugates |
| FR2882056B1 (fr) * | 2005-02-15 | 2007-06-01 | Centre Nat Rech Scient | Dipyrromethenes-bore borocarbones insatures |
| US9097667B2 (en) * | 2007-12-14 | 2015-08-04 | Biotium, Inc. | Fluorescent compounds |
| GB0819594D0 (en) * | 2008-10-24 | 2008-12-03 | Univ Coimbrra | Process |
| CN110506208A (zh) * | 2017-03-30 | 2019-11-26 | 富士胶片株式会社 | 用于测定活体样品中的测定对象物质的试剂盒及方法 |
| JP6867962B2 (ja) * | 2018-02-22 | 2021-05-12 | 富士フイルム株式会社 | 測定対象物質を測定するためのキット、蛍光標識剤および蛍光標識抗体 |
| JP2019172826A (ja) * | 2018-03-28 | 2019-10-10 | 富士フイルム株式会社 | 蛍光性化合物及びこれを用いた蛍光標識生体物質 |
| WO2019230963A1 (ja) | 2018-06-01 | 2019-12-05 | 富士フイルム株式会社 | 蛍光性化合物及びこれを用いた蛍光標識生体物質 |
| JP7344982B2 (ja) | 2019-11-21 | 2023-09-14 | 富士フイルム株式会社 | 化合物及びこれを用いた蛍光標識生体物質 |
| JP7261757B2 (ja) | 2020-02-21 | 2023-04-20 | 三菱重工機械システム株式会社 | インキ供給システムおよび方法並びに印刷機 |
-
2022
- 2022-08-18 WO PCT/JP2022/031169 patent/WO2023022187A1/ja not_active Ceased
- 2022-08-18 CN CN202280040905.4A patent/CN117460790B/zh active Active
- 2022-08-18 JP JP2023542437A patent/JPWO2023022187A1/ja active Pending
- 2022-08-18 EP EP22858505.5A patent/EP4389755A4/en active Pending
-
2023
- 2023-11-20 US US18/513,641 patent/US20240110918A1/en active Pending
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