JP2021517113A5 - - Google Patents
Info
- Publication number
- JP2021517113A5 JP2021517113A5 JP2020543533A JP2020543533A JP2021517113A5 JP 2021517113 A5 JP2021517113 A5 JP 2021517113A5 JP 2020543533 A JP2020543533 A JP 2020543533A JP 2020543533 A JP2020543533 A JP 2020543533A JP 2021517113 A5 JP2021517113 A5 JP 2021517113A5
- Authority
- JP
- Japan
- Prior art keywords
- optionally
- optionally substituted
- compound
- substituted
- rnai agent
- Prior art date
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024002413A JP7843302B2 (ja) | 2018-02-17 | 2024-01-11 | トリアルキン結合剤及び使用方法 |
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862631683P | 2018-02-17 | 2018-02-17 | |
| US62/631,683 | 2018-02-17 | ||
| US201862646739P | 2018-03-22 | 2018-03-22 | |
| US62/646,739 | 2018-03-22 | ||
| US201862663763P | 2018-04-27 | 2018-04-27 | |
| US62/663,763 | 2018-04-27 | ||
| US201962790300P | 2019-01-09 | 2019-01-09 | |
| US62/790,300 | 2019-01-09 | ||
| PCT/US2019/018232 WO2019161213A1 (en) | 2018-02-17 | 2019-02-15 | Trialkyne linking agents and methods of use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024002413A Division JP7843302B2 (ja) | 2018-02-17 | 2024-01-11 | トリアルキン結合剤及び使用方法 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021517113A JP2021517113A (ja) | 2021-07-15 |
| JPWO2019161213A5 JPWO2019161213A5 (https=) | 2022-02-24 |
| JP2021517113A5 true JP2021517113A5 (https=) | 2022-02-24 |
| JP7420727B2 JP7420727B2 (ja) | 2024-01-23 |
Family
ID=67620056
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020543533A Active JP7420727B2 (ja) | 2018-02-17 | 2019-02-15 | トリアルキン結合剤及び使用方法 |
| JP2024002413A Active JP7843302B2 (ja) | 2018-02-17 | 2024-01-11 | トリアルキン結合剤及び使用方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024002413A Active JP7843302B2 (ja) | 2018-02-17 | 2024-01-11 | トリアルキン結合剤及び使用方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20250092072A1 (https=) |
| EP (1) | EP3752166A4 (https=) |
| JP (2) | JP7420727B2 (https=) |
| CN (2) | CN120247964A (https=) |
| AU (2) | AU2019220739B2 (https=) |
| CA (1) | CA3089276A1 (https=) |
| IL (1) | IL276687B2 (https=) |
| WO (1) | WO2019161213A1 (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TN2019000308A1 (en) * | 2017-07-06 | 2021-05-07 | Arrowhead Pharmaceuticals Inc | RNAi AGENTS FOR INHIBITING EXPRESSION OF ALPHA-ENaC AND METHODS OF USE |
| WO2019210308A1 (en) | 2018-04-27 | 2019-10-31 | Arrowhead Pharmaceuticals, Inc. | Integrin targeting ligands and uses thereof |
| SG11202105577TA (en) | 2019-01-09 | 2021-06-29 | Arrowhead Pharmaceuticals Inc | Rnai agents for inhibiting expression of hif-2 alpha (epas1), compositions thereof, and methods of use |
| KR20220024153A (ko) | 2019-05-24 | 2022-03-03 | 엠피리코 인크. | 안지오포이에틴 유사 7(angptl7) 관련 질환의 치료 |
| EP4025252A4 (en) * | 2019-09-03 | 2023-10-18 | Arcturus Therapeutics, Inc. | ASIALOGLYCOPROTEIN RECEPTOR-MEDIATED ADMINISTRATION OF THERAPEUTICALLY ACTIVE CONJUGATES |
| AU2021340710A1 (en) * | 2020-09-11 | 2023-04-06 | Arrowhead Pharmaceuticals, Inc. | Skeletal muscle delivery platforms and methods of use |
| IL301187A (en) * | 2020-09-11 | 2023-05-01 | Arrowhead Pharmaceuticals Inc | RNAi agents for suppressing DUX4 expression, preparations containing them and uses thereof |
| CN116323633A (zh) * | 2020-09-11 | 2023-06-23 | 箭头药业股份有限公司 | 骨骼肌递送平台及使用方法 |
| US12486502B2 (en) | 2021-04-08 | 2025-12-02 | Arrowhead Pharmaceuticals, Inc. | RNAi agents for inhibiting expression of receptor for advanced glycation end-products, compositions thereof, and methods of use |
| CN117858949A (zh) | 2021-05-28 | 2024-04-09 | 箭头药业股份有限公司 | 用于抑制粘蛋白5AC(MUC5AC)的表达的RNAi试剂、其组合物及其使用方法 |
| CN113956206B (zh) * | 2021-10-25 | 2023-04-28 | 深圳湾实验室坪山生物医药研发转化中心 | 一种用于修饰蛋白质赖氨酸残基的探针及其制备方法 |
| US20250197859A1 (en) * | 2022-03-28 | 2025-06-19 | Empirico Inc. | Compositions and methods for the treatment of angiopoietin like 7 (angptl7) related diseases |
| KR20240163743A (ko) * | 2022-03-28 | 2024-11-19 | 엠피리코 인크. | 변형된 올리고뉴클레오티드 |
| EP4540390A2 (en) | 2022-06-15 | 2025-04-23 | Arrowhead Pharmaceuticals, Inc. | Rnai agents for inhibiting expression of superoxide dismutase 1 (sod1), compositions thereof, and methods of use |
| CN120731091A (zh) * | 2022-12-14 | 2025-09-30 | 阿尔尼拉姆医药品有限公司 | 用于肝外递送的α-Vβ-6(αvβ6)整合素配体 |
| AU2024302964A1 (en) | 2023-06-13 | 2025-12-18 | Tuojie Biotech (Shanghai) Co., Ltd. | Sirna targeting mmp7, sirna conjugate and medical use thereof |
| CN121586578A (zh) | 2023-08-24 | 2026-02-27 | 上海拓界生物医药科技有限公司 | 靶向RAGE的RNAi剂及其医药用途 |
| CN121843941A (zh) | 2023-09-27 | 2026-04-10 | 上海拓界生物医药科技有限公司 | 含三氮唑基化合物、制备方法及用途 |
| WO2025137390A1 (en) | 2023-12-20 | 2025-06-26 | Arrowhead Pharmaceuticals, Inc. | Rnai agents for inhibiting expression of activin receptor-like kinase 7 (alk7), compositions thereof, and methods of use |
| CN120309684A (zh) * | 2024-01-15 | 2025-07-15 | 武汉人福创新药物研发中心有限公司 | 靶向化合物及其用途 |
| US12551569B2 (en) | 2024-03-31 | 2026-02-17 | Arrowhead Pharmaceuticals, Inc. | RNAi agents for inhibiting expression of microtubule associated protein tau (MAPT), compositions thereof, and methods of use |
| US20260021195A1 (en) | 2024-06-20 | 2026-01-22 | Arrowhead Pharmaceuticals, Inc. | Rnai agents for inhibiting expression of huntingtin (htt), compositions thereof, and methods of use |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2021351A2 (en) | 2006-04-28 | 2009-02-11 | Centre National de la Recherche Scientifique | Method for the synthesis of triazole-containing oligonucleotide derivatives |
| GB201313201D0 (en) * | 2013-07-24 | 2013-09-04 | Univ East Anglia | Virus Detection |
| JP6584412B2 (ja) | 2014-01-15 | 2019-10-02 | ベースクリック ゲーエムベーハー | 糖修飾核酸分子 |
| JP6987641B2 (ja) * | 2015-05-12 | 2022-01-05 | ブリンクバイオ インコーポレイテッド | シリコン系薬物複合体及びその使用方法 |
| WO2018013525A1 (en) * | 2016-07-11 | 2018-01-18 | Translate Bio Ma, Inc. | Nucleic acid conjugates and uses thereof |
| TN2019000308A1 (en) * | 2017-07-06 | 2021-05-07 | Arrowhead Pharmaceuticals Inc | RNAi AGENTS FOR INHIBITING EXPRESSION OF ALPHA-ENaC AND METHODS OF USE |
-
2019
- 2019-02-15 JP JP2020543533A patent/JP7420727B2/ja active Active
- 2019-02-15 IL IL276687A patent/IL276687B2/en unknown
- 2019-02-15 CA CA3089276A patent/CA3089276A1/en active Pending
- 2019-02-15 AU AU2019220739A patent/AU2019220739B2/en active Active
- 2019-02-15 CN CN202510149001.0A patent/CN120247964A/zh active Pending
- 2019-02-15 EP EP19754398.6A patent/EP3752166A4/en active Pending
- 2019-02-15 CN CN201980013763.0A patent/CN111698995B/zh active Active
- 2019-02-15 WO PCT/US2019/018232 patent/WO2019161213A1/en not_active Ceased
-
2024
- 2024-01-11 JP JP2024002413A patent/JP7843302B2/ja active Active
- 2024-07-16 US US18/773,657 patent/US20250092072A1/en active Pending
-
2025
- 2025-11-12 AU AU2025267360A patent/AU2025267360A1/en active Pending
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