CN117460790B - 荧光性化合物及使用了该荧光性化合物的荧光标记生物物质 - Google Patents

荧光性化合物及使用了该荧光性化合物的荧光标记生物物质

Info

Publication number
CN117460790B
CN117460790B CN202280040905.4A CN202280040905A CN117460790B CN 117460790 B CN117460790 B CN 117460790B CN 202280040905 A CN202280040905 A CN 202280040905A CN 117460790 B CN117460790 B CN 117460790B
Authority
CN
China
Prior art keywords
group
compound
substituent
groups
biological substance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN202280040905.4A
Other languages
English (en)
Chinese (zh)
Other versions
CN117460790A (zh
Inventor
渡边康介
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujifilm Corp
Original Assignee
Fujifilm Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujifilm Corp filed Critical Fujifilm Corp
Publication of CN117460790A publication Critical patent/CN117460790A/zh
Application granted granted Critical
Publication of CN117460790B publication Critical patent/CN117460790B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/02Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups
    • C09B23/04Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups one >CH- group, e.g. cyanines, isocyanines, pseudocyanines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02Boron compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02Boron compounds
    • C07F5/022Boron compounds without C-boron linkages
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02Boron compounds
    • C07F5/025Boronic and borinic acid compounds
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/0066Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain being part of a carbocyclic ring,(e.g. benzene, naphtalene, cyclohexene, cyclobutenene-quadratic acid)
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B55/00Azomethine dyes
    • C09B55/009Azomethine dyes, the C-atom of the group -C=N- being part of a ring (Image)
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B69/00Dyes not provided for by a single group of this subclass
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B69/00Dyes not provided for by a single group of this subclass
    • C09B69/10Polymeric dyes; Reaction products of dyes with monomers or with macromolecular compounds
    • C09B69/105Polymeric dyes; Reaction products of dyes with monomers or with macromolecular compounds containing a methine or polymethine dye
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09KMATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00Luminescent materials, e.g. electroluminescent or chemiluminescent
    • C09K11/06Luminescent materials, e.g. electroluminescent or chemiluminescent containing organic luminescent materials
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • G01N33/533Production of labelled immunochemicals with fluorescent label
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Materials Engineering (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
CN202280040905.4A 2021-08-18 2022-08-18 荧光性化合物及使用了该荧光性化合物的荧光标记生物物质 Active CN117460790B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2021133510 2021-08-18
JP2021-133510 2021-08-18
PCT/JP2022/031169 WO2023022187A1 (ja) 2021-08-18 2022-08-18 蛍光性化合物及びこれを用いた蛍光標識生体物質

Publications (2)

Publication Number Publication Date
CN117460790A CN117460790A (zh) 2024-01-26
CN117460790B true CN117460790B (zh) 2026-01-02

Family

ID=85239876

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202280040905.4A Active CN117460790B (zh) 2021-08-18 2022-08-18 荧光性化合物及使用了该荧光性化合物的荧光标记生物物质

Country Status (5)

Country Link
US (1) US20240110918A1 (https=)
EP (1) EP4389755A4 (https=)
JP (1) JPWO2023022187A1 (https=)
CN (1) CN117460790B (https=)
WO (1) WO2023022187A1 (https=)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101946171A (zh) * 2007-12-14 2011-01-12 拜奥蒂乌姆股份有限公司 荧光化合物
EP3531132A1 (en) * 2018-02-22 2019-08-28 Fujifilm Corporation Kit for measuring substance to be measured, fluorescent labeling agent, and fluorescently labeled antibody
JP2019172826A (ja) * 2018-03-28 2019-10-10 富士フイルム株式会社 蛍光性化合物及びこれを用いた蛍光標識生体物質

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3912046B4 (de) * 1988-09-02 2004-03-25 Carnegie Mellon University Verfahren zum Markieren einer Komponente einer wäßrigen Flüssigkeit und lumineszenzphotostabiles Reaktionsprodukt
CA2125866A1 (en) * 1992-02-10 1993-08-19 Larry J. Kricka Chemiluminescent enhancers
CA2423806C (en) 2000-09-29 2009-12-22 Molecular Probes, Inc. Modified carbocyanine dyes and their conjugates
FR2882056B1 (fr) * 2005-02-15 2007-06-01 Centre Nat Rech Scient Dipyrromethenes-bore borocarbones insatures
GB0819594D0 (en) * 2008-10-24 2008-12-03 Univ Coimbrra Process
CN110506208A (zh) * 2017-03-30 2019-11-26 富士胶片株式会社 用于测定活体样品中的测定对象物质的试剂盒及方法
JP7064583B2 (ja) 2018-06-01 2022-05-10 富士フイルム株式会社 蛍光性化合物及びこれを用いた蛍光標識生体物質
JP7344982B2 (ja) 2019-11-21 2023-09-14 富士フイルム株式会社 化合物及びこれを用いた蛍光標識生体物質
JP7261757B2 (ja) 2020-02-21 2023-04-20 三菱重工機械システム株式会社 インキ供給システムおよび方法並びに印刷機

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101946171A (zh) * 2007-12-14 2011-01-12 拜奥蒂乌姆股份有限公司 荧光化合物
EP3531132A1 (en) * 2018-02-22 2019-08-28 Fujifilm Corporation Kit for measuring substance to be measured, fluorescent labeling agent, and fluorescently labeled antibody
JP2019172826A (ja) * 2018-03-28 2019-10-10 富士フイルム株式会社 蛍光性化合物及びこれを用いた蛍光標識生体物質

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Water-soluble Porphyrin as Temperature Sensor Based on Fluorescent Enhancement;FEI Qiang et al;Chem. Res. Chin. Univ.;20140331;第30卷(第3期);379-382 *

Also Published As

Publication number Publication date
EP4389755A1 (en) 2024-06-26
US20240110918A1 (en) 2024-04-04
EP4389755A4 (en) 2025-04-23
JPWO2023022187A1 (https=) 2023-02-23
WO2023022187A1 (ja) 2023-02-23
CN117460790A (zh) 2024-01-26

Similar Documents

Publication Publication Date Title
US11988667B2 (en) Fluorescent compound and fluorescent labeled biological substance using the same
JP7344982B2 (ja) 化合物及びこれを用いた蛍光標識生体物質
JP7550076B2 (ja) 蛍光色素及びこれを用いた標識生体物質
JP7359869B2 (ja) 化合物及びこれを用いた蛍光標識生体物質
CN116134044B (zh) 化合物及使用了该化合物的标记生物物质
JP7837947B2 (ja) 蛍光性化合物及びこれを用いた蛍光標識生体物質
JP7441306B2 (ja) 化合物及びこれを用いた標識生体物質
US20250314658A1 (en) Fluorescence intensity enhancer, fluorescence intensity enhancing method of fluorescently labeled target biological substance, and kit for fluorescence detection
CN117460790B (zh) 荧光性化合物及使用了该荧光性化合物的荧光标记生物物质
JPWO2018043579A1 (ja) ホスファローダミン化合物若しくはその塩、並びにそれを用いた蛍光色素
CN117460789B (zh) 化合物及使用了该化合物的标记生物物质
JP7706329B2 (ja) 蛍光性化合物及びこれを用いた蛍光標識生体物質
JP2025059908A (ja) 蛍光性化合物及びこれを用いた蛍光標識生体物質
WO2024181456A1 (ja) 化合物及びこれを用いた標識生体物質
WO2025022130A1 (en) Dendrimers comprising fluorescent dyes
CN117642414A (zh) 化合物及使用了该化合物的标记生物物质
US20250389724A1 (en) Compound and labeled biological substance using the same
CN117642412A (zh) 化合物及使用了该化合物的标记生物物质

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant