|
NL154598B
(nl)
|
1970-11-10 |
1977-09-15 |
Organon Nv |
Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
|
|
US3817837A
(en)
|
1971-05-14 |
1974-06-18 |
Syva Corp |
Enzyme amplification assay
|
|
US3939350A
(en)
|
1974-04-29 |
1976-02-17 |
Board Of Trustees Of The Leland Stanford Junior University |
Fluorescent immunoassay employing total reflection for activation
|
|
US3996345A
(en)
|
1974-08-12 |
1976-12-07 |
Syva Company |
Fluorescence quenching with immunological pairs in immunoassays
|
|
US4275149A
(en)
|
1978-11-24 |
1981-06-23 |
Syva Company |
Macromolecular environment control in specific receptor assays
|
|
US4277437A
(en)
|
1978-04-05 |
1981-07-07 |
Syva Company |
Kit for carrying out chemically induced fluorescence immunoassay
|
|
US4366241A
(en)
|
1980-08-07 |
1982-12-28 |
Syva Company |
Concentrating zone method in heterogeneous immunoassays
|
|
AU701578B2
(en)
|
1992-08-21 |
1999-02-04 |
Vrije Universiteit Brussel |
Immunoglobulins devoid of light chains
|
|
WO1994025591A1
(en)
|
1993-04-29 |
1994-11-10 |
Unilever N.V. |
PRODUCTION OF ANTIBODIES OR (FUNCTIONALIZED) FRAGMENTS THEREOF DERIVED FROM HEAVY CHAIN IMMUNOGLOBULINS OF $i(CAMELIDAE)
|
|
FR2708622B1
(fr)
|
1993-08-02 |
1997-04-18 |
Raymond Hamers |
Vecteur recombinant contenant une séquence d'un gène de lipoprotéine de structure pour l'expression de séquences de nucléotides.
|
|
EP0739981A1
(en)
|
1995-04-25 |
1996-10-30 |
Vrije Universiteit Brussel |
Variable fragments of immunoglobulins - use for therapeutic or veterinary purposes
|
|
ES2294799T3
(es)
|
1996-06-27 |
2008-04-01 |
Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw. |
Moleculas de anticuerpos que interactuan especificamente con el sitio activo o hendidura de una molecula diana.
|
|
WO1999037681A2
(en)
|
1998-01-26 |
1999-07-29 |
Unilever Plc |
Method for producing antibody fragments
|
|
BR9916765A
(pt)
|
1999-01-05 |
2001-09-25 |
Unilever Nv |
Processo para produzir um material imunoadsorvente, uso de uma proteìna que é ligada por meio de uma ligação covalente a um fragmento de anticorpo, material imunadsorvente, uso de um material, e, kit de teste diagnóstico
|
|
DE60013767T3
(de)
|
1999-01-19 |
2009-07-09 |
Unilever N.V. |
Verfahren zur herstellung von antikörperfragmenten
|
|
CN1252264C
(zh)
|
1999-04-22 |
2006-04-19 |
荷兰联合利华有限公司 |
利用单价抗原-结合蛋白抑制病毒感染
|
|
US6479280B1
(en)
|
1999-09-24 |
2002-11-12 |
Vlaams Interuniversitair Institutuut Voor Biotechnologie Vzw |
Recombinant phages capable of entering host cells via specific interaction with an artificial receptor
|
|
DE60042789D1
(de)
|
1999-11-29 |
2009-10-01 |
Bac Ip B V |
Immobilisierte antigenbindende moleküle aus einer domäne
|
|
AU1859201A
(en)
|
1999-11-29 |
2001-06-12 |
Unilever Plc |
Immobilisation of proteins
|
|
ES2324280T3
(es)
|
2000-03-14 |
2009-08-04 |
Unilever N.V. |
Dominios variables de la cadena pesada de anticuerpos frente a lipasas dieteticas humanas y sus usos.
|
|
WO2001090190A2
(en)
|
2000-05-26 |
2001-11-29 |
National Research Council Of Canada |
Single-domain antigen-binding antibody fragments derived from llama antibodies
|
|
ATE513854T1
(de)
|
2000-12-13 |
2011-07-15 |
Bac Ip B V |
Proteinraster aus variablen domänen der schweren immunoglobulinkette von kamelen
|
|
EP1433793A4
(en)
|
2001-09-13 |
2006-01-25 |
Inst Antibodies Co Ltd |
METHOD FOR CREATING A CAMEL ANTIBODY LIBRARY
|
|
JP2005289809A
(ja)
|
2001-10-24 |
2005-10-20 |
Vlaams Interuniversitair Inst Voor Biotechnologie Vzw (Vib Vzw) |
突然変異重鎖抗体
|
|
EP1456410A2
(en)
|
2001-12-11 |
2004-09-15 |
AlgoNomics N.V. |
Method for displaying loops from immunoglobulin domains in different contexts
|
|
EP1456237A2
(en)
|
2001-12-21 |
2004-09-15 |
Vlaams Interuniversitair Instituut voor Biotechnologie vzw. |
Method for cloning of variable domain sequences
|
|
WO2003055527A2
(en)
|
2002-01-03 |
2003-07-10 |
Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw |
Immunoconjugates useful for treatment of tumours
|
|
WO2005044858A1
(en)
|
2003-11-07 |
2005-05-19 |
Ablynx N.V. |
Camelidae single domain antibodies vhh directed against epidermal growth factor receptor and uses therefor
|
|
WO2004041867A2
(en)
|
2002-11-08 |
2004-05-21 |
Ablynx N.V. |
Camelidae antibodies against imminoglobulin e and use thereof for the treatment of allergic disorders
|
|
CA2505316C
(en)
|
2002-11-08 |
2014-08-05 |
Ablynx N.V. |
Single domain antibodies directed against tumour necrosis factor-alpha and uses therefor
|
|
EP1587838B1
(en)
|
2003-01-10 |
2015-04-15 |
Ablynx N.V. |
Therapeutic polypeptides, homologues thereof, fragments thereof and their use in modulating platelet-mediated aggregation
|
|
WO2006040153A2
(en)
|
2004-10-13 |
2006-04-20 |
Ablynx N.V. |
Single domain camelide anti -amyloid beta antibodies and polypeptides comprising the same for the treatment and diagnosis of degenarative neural diseases such as alzheimer's disease
|
|
AU2005325801A1
(en)
|
2005-01-31 |
2006-08-03 |
Ablynx N.V. |
Method for generating variable domain sequences of heavy chain antibodies
|
|
WO2006122787A1
(en)
|
2005-05-18 |
2006-11-23 |
Ablynx Nv |
Serum albumin binding proteins
|
|
ES2852423T3
(es)
|
2005-05-20 |
2021-09-13 |
Ablynx Nv |
NanobodiesTM mejorados para el tratamiento de trastornos mediados por agregación
|
|
EP1934259A2
(en)
|
2005-10-11 |
2008-06-25 |
Ablynx N.V. |
Nanobodies and polypeptides against egfr and igf-ir
|
|
EP2057191A1
(en)
|
2006-08-18 |
2009-05-13 |
Ablynx N.V. |
Amino acid sequences directed against il-6r and polypeptides comprising the same for the treatment of deseases and disorders associated with il-6-mediated signalling
|
|
JP2010518839A
(ja)
|
2007-02-21 |
2010-06-03 |
アブリンクス エン.ヴェー. |
血管内皮増殖因子に指向性を有するアミノ酸配列、及び過度の及び/もしくは病的な血管形成又は血管新生を特徴とする症状及び疾患を治療するためにこれを含むポリペプチド
|
|
CN101796072B
(zh)
|
2007-05-24 |
2014-09-24 |
埃博灵克斯股份有限公司 |
用于治疗骨疾病和病症的针对rank-l的氨基酸序列以及包括其的多肽
|
|
DK2723769T4
(da)
|
2011-06-23 |
2022-09-05 |
Ablynx Nv |
Teknikker til at forudsige, påvise og reducere uspecifik proteininterferens i assays, som involverer variable immunglobulin-enkeltdomæner
|
|
PL3248986T3
(pl)
|
2014-05-16 |
2022-05-16 |
Ablynx Nv |
Domeny zmienne immunoglobuliny
|
|
AU2016365834B2
(en)
*
|
2015-12-08 |
2023-09-28 |
Regeneron Pharmaceuticals, Inc. |
Compositions and methods for internalizing enzymes
|
|
FI3635009T3
(fi)
*
|
2017-06-07 |
2026-04-07 |
Regeneron Pharma |
Koostumuksia ja menetelmiä entsyymien internalisoimiseksi
|
|
CN113301925A
(zh)
*
|
2018-12-19 |
2021-08-24 |
小利兰·斯坦福大学理事会 |
用于溶酶体靶向的双官能分子以及相关的组合物和方法
|
|
EP4378485A3
(en)
*
|
2019-03-08 |
2024-08-28 |
LinXis B.V. |
Internalizing binding molecules targeting receptors involved in cell proliferation or cell differentiation
|
|
CA3169792A1
(en)
|
2020-03-05 |
2021-09-10 |
Umc Utrecht Holding B.V. |
Membrane ubiquitin ligases to target protein degradation
|