JPWO2020138487A5 - - Google Patents
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- JPWO2020138487A5 JPWO2020138487A5 JP2020562545A JP2020562545A JPWO2020138487A5 JP WO2020138487 A5 JPWO2020138487 A5 JP WO2020138487A5 JP 2020562545 A JP2020562545 A JP 2020562545A JP 2020562545 A JP2020562545 A JP 2020562545A JP WO2020138487 A5 JPWO2020138487 A5 JP WO2020138487A5
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- acid sequence
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- Prior art date
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- 108090000765 processed proteins & peptides Proteins 0.000 claims description 7
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- 102000007238 Transferrin Receptors Human genes 0.000 claims 5
- 108010033576 Transferrin Receptors Proteins 0.000 claims 5
- 210000004027 cell Anatomy 0.000 claims 5
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 claims 4
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- KZSNJWFQEVHDMF-BYPYZUCNSA-N L-valine Chemical compound CC(C)[C@H](N)C(O)=O KZSNJWFQEVHDMF-BYPYZUCNSA-N 0.000 claims 4
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- 102000052116 epidermal growth factor receptor activity proteins Human genes 0.000 claims 4
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- YOHYSYJDKVYCJI-UHFFFAOYSA-N n-[3-[[6-[3-(trifluoromethyl)anilino]pyrimidin-4-yl]amino]phenyl]cyclopropanecarboxamide Chemical compound FC(F)(F)C1=CC=CC(NC=2N=CN=C(NC=3C=C(NC(=O)C4CC4)C=CC=3)C=2)=C1 YOHYSYJDKVYCJI-UHFFFAOYSA-N 0.000 claims 4
- 125000002987 valine group Chemical group [H]N([H])C([H])(C(*)=O)C([H])(C([H])([H])[H])C([H])([H])[H] 0.000 claims 4
- 239000004471 Glycine Substances 0.000 claims 3
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- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims 2
- 102220614728 Ras-related protein Rab-3B_V55E_mutation Human genes 0.000 claims 2
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- 125000003275 alpha amino acid group Chemical group 0.000 description 27
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024096802A JP2024119984A (ja) | 2018-12-28 | 2024-06-14 | ＴｆＲに結合するバイスペシフィック抗体 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2018248334 | 2018-12-28 | ||
| JP2018248334 | 2018-12-28 | ||
| PCT/JP2019/051594 WO2020138487A1 (ja) | 2018-12-28 | 2019-12-27 | ＴｆＲに結合するバイスペシフィック抗体 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024096802A Division JP2024119984A (ja) | 2018-12-28 | 2024-06-14 | ＴｆＲに結合するバイスペシフィック抗体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPWO2020138487A1 JPWO2020138487A1 (ja) | 2021-11-11 |
| JPWO2020138487A5 true JPWO2020138487A5 (https=) | 2023-08-28 |
| JP7506607B2 JP7506607B2 (ja) | 2024-06-26 |
Family
ID=71125764
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020562545A Active JP7506607B2 (ja) | 2018-12-28 | 2019-12-27 | ＴｆＲに結合するバイスペシフィック抗体 |
| JP2024096802A Pending JP2024119984A (ja) | 2018-12-28 | 2024-06-14 | ＴｆＲに結合するバイスペシフィック抗体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024096802A Pending JP2024119984A (ja) | 2018-12-28 | 2024-06-14 | ＴｆＲに結合するバイスペシフィック抗体 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US12258413B2 (https=) |
| EP (1) | EP3903816A4 (https=) |
| JP (2) | JP7506607B2 (https=) |
| KR (1) | KR20210108961A (https=) |
| CN (1) | CN113226371B (https=) |
| AU (1) | AU2019413278B2 (https=) |
| BR (1) | BR112021012569A2 (https=) |
| CA (1) | CA3125316A1 (https=) |
| MX (1) | MX2021007797A (https=) |
| MY (1) | MY210422A (https=) |
| SG (1) | SG11202106990PA (https=) |
| TW (2) | TWI873112B (https=) |
| WO (1) | WO2020138487A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113563473A (zh) * | 2020-04-29 | 2021-10-29 | 三生国健药业（上海）股份有限公司 | 四价双特异性抗体、其制备方法和用途 |
| EP4434548A1 (en) | 2021-11-15 | 2024-09-25 | Systimmune, Inc. | Bispecific antibody-camptothecin drug conjugate and pharmaceutical use thereof |
| EP4688846A1 (en) * | 2023-03-24 | 2026-02-11 | BioArctic AB | Antibody binding to the protease-like domain of the human transferrin receptor htfr1 |
| AU2024299328A1 (en) | 2023-07-21 | 2026-01-22 | Marrow Therapeutics, Inc. | Hematopoietic cell targeting conjugates and related methods |
| WO2025090898A1 (en) * | 2023-10-26 | 2025-05-01 | Biogen Ma Inc. | Anti-transferrin receptor antibodies and uses thereof cross reference to related applications |
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| WO2014189973A2 (en) | 2013-05-20 | 2014-11-27 | Genentech, Inc. | Anti-transferrin receptor antibodies and methods of use |
| CN104211814A (zh) | 2013-05-29 | 2014-12-17 | 三星电子株式会社 | 用于消耗靶膜蛋白的组合物 |
| TWI853985B (zh) * | 2013-12-04 | 2024-09-01 | 日商中外製藥股份有限公司 | 因應化合物濃度使抗原結合能力變化的抗原結合分子及其資料庫 |
| SG11201608253XA (en) * | 2014-04-04 | 2016-10-28 | Kyowa Hakko Kirin Co Ltd | Anti-death receptor 3 (dr3) antagonistic antibodies with reduced agonistic activity |
| EP3221362B1 (en) * | 2014-11-19 | 2019-07-24 | F.Hoffmann-La Roche Ag | Anti-transferrin receptor antibodies and methods of use |
| EP3221361B1 (en) * | 2014-11-19 | 2021-04-21 | Genentech, Inc. | Anti-transferrin receptor / anti-bace1 multispecific antibodies and methods of use |
| SG11201705632UA (en) * | 2015-01-08 | 2017-08-30 | Kyowa Hakko Kirin Co Ltd | Bispecific antibody binding to trailr2 and psma |
| MX391086B (es) * | 2015-06-24 | 2025-03-21 | Hoffmann La Roche | Anticuerpos anti-receptor de transferrina con afinidad diseñada. |
| CA2992262A1 (en) * | 2015-07-15 | 2017-01-19 | Kyowa Hakko Kirin Co., Ltd. | Antibody which specifically binds to human crth2 |
| KR20190005944A (ko) | 2016-05-09 | 2019-01-16 | 애넥슨, 인코포레이티드 | 척수성 근위축 치료용 조성물 및 방법 |
| KR102156626B1 (ko) | 2018-07-16 | 2020-09-17 | 주식회사 셀바스에이아이 | 운동 처방 정보를 제공하는 서버 및 컴퓨터 프로그램 |
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2019
- 2019-12-27 JP JP2020562545A patent/JP7506607B2/ja active Active
- 2019-12-27 BR BR112021012569-8A patent/BR112021012569A2/pt unknown
- 2019-12-27 TW TW108148133A patent/TWI873112B/zh active
- 2019-12-27 EP EP19901837.5A patent/EP3903816A4/en active Pending
- 2019-12-27 US US17/418,447 patent/US12258413B2/en active Active
- 2019-12-27 CA CA3125316A patent/CA3125316A1/en active Pending
- 2019-12-27 MX MX2021007797A patent/MX2021007797A/es unknown
- 2019-12-27 SG SG11202106990PA patent/SG11202106990PA/en unknown
- 2019-12-27 TW TW114101537A patent/TWI907249B/zh active
- 2019-12-27 CN CN201980086662.6A patent/CN113226371B/zh active Active
- 2019-12-27 KR KR1020217019406A patent/KR20210108961A/ko active Pending
- 2019-12-27 WO PCT/JP2019/051594 patent/WO2020138487A1/ja not_active Ceased
- 2019-12-27 MY MYPI2021003612A patent/MY210422A/en unknown
- 2019-12-27 AU AU2019413278A patent/AU2019413278B2/en active Active
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2024
- 2024-06-14 JP JP2024096802A patent/JP2024119984A/ja active Pending
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2025
- 2025-02-19 US US19/057,265 patent/US20250250352A1/en active Pending
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