JPWO2019175368A5 - - Google Patents

Info

Publication number

JPWO2019175368A5

JPWO2019175368A5 JP2020548991A JP2020548991A JPWO2019175368A5 JP WO2019175368 A5 JPWO2019175368 A5 JP WO2019175368A5 JP 2020548991 A JP2020548991 A JP 2020548991A JP 2020548991 A JP2020548991 A JP 2020548991A JP WO2019175368 A5 JPWO2019175368 A5 JP WO2019175368A5

Authority

JP

Japan

Prior art keywords

antigen

seq

amino acid

acid sequence

set forth

Prior art date

2022-03-15

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
• Discuss

• 125000003275 alpha amino acid group Chemical group 0.000 claims 22
• 239000000427 antigen Substances 0.000 claims 20
• 102000036639 antigens Human genes 0.000 claims 20
• 108091007433 antigens Proteins 0.000 claims 20
• 102000025171 antigen binding proteins Human genes 0.000 claims 17
• 108091000831 antigen binding proteins Proteins 0.000 claims 17
• 102000052116 epidermal growth factor receptor activity proteins Human genes 0.000 claims 12
• 108700015053 epidermal growth factor receptor activity proteins Proteins 0.000 claims 12
• YOHYSYJDKVYCJI-UHFFFAOYSA-N n-[3-[[6-[3-(trifluoromethyl)anilino]pyrimidin-4-yl]amino]phenyl]cyclopropanecarboxamide Chemical compound FC(F)(F)C1=CC=CC(NC=2N=CN=C(NC=3C=C(NC(=O)C4CC4)C=CC=3)C=2)=C1 YOHYSYJDKVYCJI-UHFFFAOYSA-N 0.000 claims 12
• 101100334515 Homo sapiens FCGR3A gene Proteins 0.000 claims 11
• 102100029193 Low affinity immunoglobulin gamma Fc region receptor III-A Human genes 0.000 claims 11
• 108090000765 processed proteins & peptides Proteins 0.000 claims 9
• 229920001184 polypeptide Polymers 0.000 claims 6
• 102000004196 processed proteins & peptides Human genes 0.000 claims 6
• 210000004899 c-terminal region Anatomy 0.000 claims 4
• 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 3
• 239000012634 fragment Substances 0.000 claims 3
• 239000008194 pharmaceutical composition Substances 0.000 claims 3
• 206010028980 Neoplasm Diseases 0.000 claims 2
• 102000007562 Serum Albumin Human genes 0.000 claims 2
• 108010071390 Serum Albumin Proteins 0.000 claims 2
• 201000011510 cancer Diseases 0.000 claims 2
• 210000004027 cell Anatomy 0.000 claims 2
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
• 206010009944 Colon cancer Diseases 0.000 claims 1
• 208000001333 Colorectal Neoplasms Diseases 0.000 claims 1
• 108010073807 IgG Receptors Proteins 0.000 claims 1
• 102000009490 IgG Receptors Human genes 0.000 claims 1
• 102100026120 IgG receptor FcRn large subunit p51 Human genes 0.000 claims 1
• 206010058467 Lung neoplasm malignant Diseases 0.000 claims 1
• 102000023732 binding proteins Human genes 0.000 claims 1
• 108091008324 binding proteins Proteins 0.000 claims 1
• 108010087914 epidermal growth factor receptor VIII Proteins 0.000 claims 1
• 208000005017 glioblastoma Diseases 0.000 claims 1
• 201000010536 head and neck cancer Diseases 0.000 claims 1
• 208000014829 head and neck neoplasm Diseases 0.000 claims 1
• 201000005202 lung cancer Diseases 0.000 claims 1
• 208000020816 lung neoplasm Diseases 0.000 claims 1
• 108010068617 neonatal Fc receptor Proteins 0.000 claims 1
• 102000004169 proteins and genes Human genes 0.000 claims 1
• 108090000623 proteins and genes Proteins 0.000 claims 1