JPWO2022250050A5 - - Google Patents

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Publication number
JPWO2022250050A5
JPWO2022250050A5 JP2023523485A JP2023523485A JPWO2022250050A5 JP WO2022250050 A5 JPWO2022250050 A5 JP WO2022250050A5 JP 2023523485 A JP2023523485 A JP 2023523485A JP 2023523485 A JP2023523485 A JP 2023523485A JP WO2022250050 A5 JPWO2022250050 A5 JP WO2022250050A5
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JP
Japan
Prior art keywords
nucleic acid
double
acid strand
stranded nucleic
acid complex
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023523485A
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English (en)
Japanese (ja)
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JPWO2022250050A1 (https=
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/JP2022/021251 external-priority patent/WO2022250050A1/ja
Publication of JPWO2022250050A1 publication Critical patent/JPWO2022250050A1/ja
Publication of JPWO2022250050A5 publication Critical patent/JPWO2022250050A5/ja
Pending legal-status Critical Current

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JP2023523485A 2021-05-25 2022-05-24 Pending JPWO2022250050A1 (https=)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2021087941 2021-05-25
PCT/JP2022/021251 WO2022250050A1 (ja) 2021-05-25 2022-05-24 scpBNA又はAmNAを含むヘテロ核酸

Publications (2)

Publication Number Publication Date
JPWO2022250050A1 JPWO2022250050A1 (https=) 2022-12-01
JPWO2022250050A5 true JPWO2022250050A5 (https=) 2025-06-03

Family

ID=84228791

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023523485A Pending JPWO2022250050A1 (https=) 2021-05-25 2022-05-24

Country Status (5)

Country Link
US (1) US20240240183A1 (https=)
EP (1) EP4349986A4 (https=)
JP (1) JPWO2022250050A1 (https=)
CA (1) CA3221584A1 (https=)
WO (1) WO2022250050A1 (https=)

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5264423A (en) 1987-03-25 1993-11-23 The United States Of America As Represented By The Department Of Health And Human Services Inhibitors for replication of retroviruses and for the expression of oncogene products
US5276019A (en) 1987-03-25 1994-01-04 The United States Of America As Represented By The Department Of Health And Human Services Inhibitors for replication of retroviruses and for the expression of oncogene products
US5955599A (en) 1995-06-01 1999-09-21 Hybridon, Inc. Process for making oligonucleotides containing o- and s- methylphosphotriester internucleoside linkages
WO2005073378A1 (en) * 2004-01-30 2005-08-11 Santaris Pharma A/S MODIFIED SHORT INTERFERING RNA (MODIFIED siRNA)
EP2023940B1 (en) 2006-05-05 2011-06-22 Isis Pharmaceuticals, Inc. Compounds and methods for modulating expression of sglt2
ES2603379T3 (es) 2006-10-09 2017-02-27 Roche Innovation Center Copenhagen A/S Compuestos antagonistas de ARN para la modulación de PCSK9
WO2008049085A1 (en) 2006-10-18 2008-04-24 Isis Pharmaceuticals, Inc. Antisense compounds
AU2012353330B2 (en) 2011-12-16 2018-04-19 National University Corporation Tokyo Medical And Dental University Chimeric double-stranded nucleic acid
ES2700277T3 (es) 2013-05-30 2019-02-14 Univ Nat Corp Tokyo Medical & Dental Agentes de doble cadena para el suministro de oligonucleótidos terapéuticos
WO2015125783A1 (ja) * 2014-02-18 2015-08-27 国立大学法人大阪大学 架橋型ヌクレオシドおよびヌクレオチド
DK3137476T3 (da) 2014-04-28 2019-11-18 Ionis Pharmaceuticals Inc Linker-modificerede oligomerforbindelser
EP3221330B1 (en) 2014-11-18 2026-04-22 Zata Pharmaceuticals Inc. Phosphoramidite synthones for the synthesis of self-neutralizing oligonucleotide compounds
EP3517610A4 (en) * 2016-09-23 2020-05-27 National University Corporation Tokyo Medical and Dental University THROUGH HETERODUPLEX NUCLEIC ACID THROUGH BLOOD BRAIN CABINET
US11260134B2 (en) 2016-09-29 2022-03-01 National University Corporation Tokyo Medical And Dental University Double-stranded nucleic acid complex having overhang
JPWO2018221649A1 (ja) * 2017-05-31 2020-04-02 協和キリン株式会社 Apcsの発現を抑制する核酸
PE20211783A1 (es) * 2018-11-08 2021-09-08 Aligos Therapeutics Inc Polimeros oligonucleotidos que inhiben el transporte de antigenos y metodos
EP3954395A4 (en) * 2019-04-08 2023-06-28 National University Corporation Tokyo Medical and Dental University Pharmaceutical composition for muscle disease treatment
JP7793144B2 (ja) * 2019-10-11 2026-01-05 国立大学法人東京科学大学 修飾ヘテロ核酸
JP7537896B2 (ja) 2019-11-21 2024-08-21 日本無機株式会社 エアフィルタ

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