JPWO2022250050A5 - - Google Patents
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- Publication number
- JPWO2022250050A5 JPWO2022250050A5 JP2023523485A JP2023523485A JPWO2022250050A5 JP WO2022250050 A5 JPWO2022250050 A5 JP WO2022250050A5 JP 2023523485 A JP2023523485 A JP 2023523485A JP 2023523485 A JP2023523485 A JP 2023523485A JP WO2022250050 A5 JPWO2022250050 A5 JP WO2022250050A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- double
- acid strand
- stranded nucleic
- acid complex
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021087941 | 2021-05-25 | ||
| PCT/JP2022/021251 WO2022250050A1 (ja) | 2021-05-25 | 2022-05-24 | ｓｃｐＢＮＡ又はＡｍＮＡを含むヘテロ核酸 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2022250050A1 JPWO2022250050A1 (https=) | 2022-12-01 |
| JPWO2022250050A5 true JPWO2022250050A5 (https=) | 2025-06-03 |
Family
ID=84228791
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023523485A Pending JPWO2022250050A1 (https=) | 2021-05-25 | 2022-05-24 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20240240183A1 (https=) |
| EP (1) | EP4349986A4 (https=) |
| JP (1) | JPWO2022250050A1 (https=) |
| CA (1) | CA3221584A1 (https=) |
| WO (1) | WO2022250050A1 (https=) |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5276019A (en) | 1987-03-25 | 1994-01-04 | The United States Of America As Represented By The Department Of Health And Human Services | Inhibitors for replication of retroviruses and for the expression of oncogene products |
| US5264423A (en) | 1987-03-25 | 1993-11-23 | The United States Of America As Represented By The Department Of Health And Human Services | Inhibitors for replication of retroviruses and for the expression of oncogene products |
| US5955599A (en) | 1995-06-01 | 1999-09-21 | Hybridon, Inc. | Process for making oligonucleotides containing o- and s- methylphosphotriester internucleoside linkages |
| WO2005073378A1 (en) * | 2004-01-30 | 2005-08-11 | Santaris Pharma A/S | MODIFIED SHORT INTERFERING RNA (MODIFIED siRNA) |
| JP2009536222A (ja) | 2006-05-05 | 2009-10-08 | アイシス ファーマシューティカルズ， インコーポレーテッド | Ｐｃｓｋ９の発現を調節するための化合物および方法 |
| CA2666191C (en) | 2006-10-09 | 2017-07-11 | Santaris Pharma A/S | Rna antagonist compounds for the modulation of pcsk9 |
| ES2526295T5 (es) | 2006-10-18 | 2021-05-04 | Ionis Pharmaceuticals Inc | Compuestos antisentido |
| JP6112569B2 (ja) * | 2011-12-16 | 2017-04-12 | 国立大学法人 東京医科歯科大学 | キメラ２重鎖核酸 |
| EP3004347B1 (en) | 2013-05-30 | 2018-09-26 | National University Corporation Tokyo Medical and Dental University | Double-stranded agents for delivering therapeutic oligonucleotides |
| CN106103463B (zh) * | 2014-02-18 | 2018-11-30 | 国立大学法人大阪大学 | 桥连型核苷和核苷酸 |
| WO2015168172A1 (en) | 2014-04-28 | 2015-11-05 | Isis Pharmaceuticals, Inc. | Linkage modified oligomeric compounds |
| WO2016081600A1 (en) | 2014-11-18 | 2016-05-26 | Zata Pharmaceuticals, Inc. | Phosphoramidite synthones for the synthesis of self-neutralizing oligonucleotide compounds |
| EP3517610A4 (en) * | 2016-09-23 | 2020-05-27 | National University Corporation Tokyo Medical and Dental University | THROUGH HETERODUPLEX NUCLEIC ACID THROUGH BLOOD BRAIN CABINET |
| US11260134B2 (en) | 2016-09-29 | 2022-03-01 | National University Corporation Tokyo Medical And Dental University | Double-stranded nucleic acid complex having overhang |
| KR20200014320A (ko) * | 2017-05-31 | 2020-02-10 | 쿄와 기린 가부시키가이샤 | Apcs의 발현을 억제하는 핵산 |
| PE20211783A1 (es) * | 2018-11-08 | 2021-09-08 | Aligos Therapeutics Inc | Polimeros oligonucleotidos que inhiben el transporte de antigenos y metodos |
| CN113677374A (zh) * | 2019-04-08 | 2021-11-19 | 国立大学法人东京医科齿科大学 | 肌疾病治疗用药物组合物 |
| EP4043565A4 (en) * | 2019-10-11 | 2024-01-24 | National University Corporation Tokyo Medical and Dental University | MODIFIED HETERONUCLEIC ACID |
| JP7537896B2 (ja) | 2019-11-21 | 2024-08-21 | 日本無機株式会社 | エアフィルタ |
-
2022
- 2022-05-24 EP EP22811320.5A patent/EP4349986A4/en active Pending
- 2022-05-24 CA CA3221584A patent/CA3221584A1/en active Pending
- 2022-05-24 JP JP2023523485A patent/JPWO2022250050A1/ja active Pending
- 2022-05-24 WO PCT/JP2022/021251 patent/WO2022250050A1/ja not_active Ceased
- 2022-05-24 US US18/563,128 patent/US20240240183A1/en active Pending
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