JPWO2021187392A5 - - Google Patents

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Publication number
JPWO2021187392A5
JPWO2021187392A5 JP2022508332A JP2022508332A JPWO2021187392A5 JP WO2021187392 A5 JPWO2021187392 A5 JP WO2021187392A5 JP 2022508332 A JP2022508332 A JP 2022508332A JP 2022508332 A JP2022508332 A JP 2022508332A JP WO2021187392 A5 JPWO2021187392 A5 JP WO2021187392A5
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JP
Japan
Prior art keywords
nucleic acid
double
acid strand
complex according
stranded nucleic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022508332A
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English (en)
Japanese (ja)
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JPWO2021187392A1 (https=
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/JP2021/010214 external-priority patent/WO2021187392A1/ja
Publication of JPWO2021187392A1 publication Critical patent/JPWO2021187392A1/ja
Publication of JPWO2021187392A5 publication Critical patent/JPWO2021187392A5/ja
Pending legal-status Critical Current

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JP2022508332A 2020-03-16 2021-03-12 Pending JPWO2021187392A1 (https=)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2020045137 2020-03-16
PCT/JP2021/010214 WO2021187392A1 (ja) 2020-03-16 2021-03-12 モルホリノ核酸を含むヘテロ核酸

Publications (2)

Publication Number Publication Date
JPWO2021187392A1 JPWO2021187392A1 (https=) 2021-09-23
JPWO2021187392A5 true JPWO2021187392A5 (https=) 2024-03-19

Family

ID=77771533

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022508332A Pending JPWO2021187392A1 (https=) 2020-03-16 2021-03-12

Country Status (4)

Country Link
US (1) US20230174981A1 (https=)
EP (1) EP4123023A4 (https=)
JP (1) JPWO2021187392A1 (https=)
WO (1) WO2021187392A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2024071362A1 (https=) * 2022-09-30 2024-04-04
JPWO2024106545A1 (https=) * 2022-11-18 2024-05-23
WO2026034445A1 (ja) * 2024-08-05 2026-02-12 日本新薬株式会社 ホスホロジアミデートモルフォリノオリゴ核酸（ｐｍｏ）とポリアニオンとを含む、ｐｍｏ複合体

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1638557A4 (en) * 2003-06-27 2007-11-07 Univ Tel Aviv Future Tech Dev INHIBITORS OF GLYCOGEN SYNTHASE KINASE-3
JP2009536222A (ja) 2006-05-05 2009-10-08 アイシス ファーマシューティカルズ， インコーポレーテッド Ｐｃｓｋ９の発現を調節するための化合物および方法
CA2666191C (en) 2006-10-09 2017-07-11 Santaris Pharma A/S Rna antagonist compounds for the modulation of pcsk9
ES2526295T5 (es) 2006-10-18 2021-05-04 Ionis Pharmaceuticals Inc Compuestos antisentido
JP6112569B2 (ja) * 2011-12-16 2017-04-12 国立大学法人 東京医科歯科大学 キメラ２重鎖核酸
EP3004347B1 (en) * 2013-05-30 2018-09-26 National University Corporation Tokyo Medical and Dental University Double-stranded agents for delivering therapeutic oligonucleotides
AU2014282666A1 (en) * 2013-06-16 2016-01-07 National University Corporation Tokyo Medical And Dental University Double-stranded antisense nucleic acid with exon-skipping effect
JP6707028B2 (ja) * 2013-12-09 2020-06-10 ベイラー カレッジ オブ メディスンＢａｙｌｏｒ Ｃｏｌｌｅｇｅ Ｏｆ Ｍｅｄｉｃｉｎｅ 心筋細胞新生におけるｈｉｐｐｏ及びジストロフィン複合体シグナル伝達
MD3464306T2 (ro) * 2016-05-24 2024-08-31 Sarepta Therapeutics Inc Procedee de preparare a oligomerilor morfolino fosforodiamidați
US11260134B2 (en) 2016-09-29 2022-03-01 National University Corporation Tokyo Medical And Dental University Double-stranded nucleic acid complex having overhang
WO2018165541A1 (en) * 2017-03-10 2018-09-13 The Board Of Regents Of The University Of Texas System Treatment of fuchs' endothelial corneal dystrophy
JP7605577B2 (ja) 2018-09-19 2024-12-24 東洋製罐グループホールディングス株式会社 二重容器の製造方法

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