JPWO2022101486A5 - - Google Patents
Download PDFInfo
- Publication number
- JPWO2022101486A5 JPWO2022101486A5 JP2023528680A JP2023528680A JPWO2022101486A5 JP WO2022101486 A5 JPWO2022101486 A5 JP WO2022101486A5 JP 2023528680 A JP2023528680 A JP 2023528680A JP 2023528680 A JP2023528680 A JP 2023528680A JP WO2022101486 A5 JPWO2022101486 A5 JP WO2022101486A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- lipid
- formulation
- cryoprotectant
- mrna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063114478P | 2020-11-16 | 2020-11-16 | |
| US63/114,478 | 2020-11-16 | ||
| EPPCT/EP2020/082602 | 2020-11-18 | ||
| EP2020082602 | 2020-11-18 | ||
| PCT/EP2021/081741 WO2022101486A1 (en) | 2020-11-16 | 2021-11-15 | Pharmaceutical compositions comprising particles and mrna and methods for preparing and storing the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023552678A JP2023552678A (ja) | 2023-12-19 |
| JPWO2022101486A5 true JPWO2022101486A5 (enrdf_load_stackoverflow) | 2024-11-22 |
Family
ID=78617419
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023528680A Pending JP2023552678A (ja) | 2020-11-16 | 2021-11-15 | 粒子およびｍＲＮＡを含む医薬組成物ならびにそれを調製および貯蔵する方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20240033344A1 (enrdf_load_stackoverflow) |
| EP (1) | EP4243787A1 (enrdf_load_stackoverflow) |
| JP (1) | JP2023552678A (enrdf_load_stackoverflow) |
| AU (1) | AU2021377746A1 (enrdf_load_stackoverflow) |
| CA (1) | CA3198309A1 (enrdf_load_stackoverflow) |
| WO (2) | WO2022101486A1 (enrdf_load_stackoverflow) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11524023B2 (en) * | 2021-02-19 | 2022-12-13 | Modernatx, Inc. | Lipid nanoparticle compositions and methods of formulating the same |
| CN114989182B (zh) * | 2022-06-23 | 2023-06-23 | 尧唐(上海)生物科技有限公司 | 脂质化合物、包含其的组合物及应用 |
| WO2024006863A1 (en) * | 2022-06-30 | 2024-01-04 | Precision NanoSystems ULC | Lipid nanoparticle formulations for vaccines |
| CN115869394A (zh) * | 2022-07-21 | 2023-03-31 | 中国食品药品检定研究院 | 核酸佐剂、含有所述核酸佐剂的疫苗及应用 |
| KR20250124242A (ko) * | 2022-12-23 | 2025-08-19 | 일라이 릴리 앤드 캄파니 | 지질 나노입자 제제의 안정화 |
| WO2024160828A1 (en) * | 2023-01-31 | 2024-08-08 | BioNTech SE | Compositions and methods |
| US11833224B1 (en) * | 2023-02-08 | 2023-12-05 | Leuvian Llc | Lyoprotectant compositions and uses thereof |
| WO2024184500A1 (en) * | 2023-03-08 | 2024-09-12 | CureVac SE | Novel lipid nanoparticle formulations for delivery of nucleic acids |
| WO2024193827A1 (en) * | 2023-03-23 | 2024-09-26 | BioNTech SE | Stabilized nucleic acid compositions and methods for preparing, storing and using the same |
| EP4442256A1 (en) * | 2023-04-04 | 2024-10-09 | Københavns Universitet | Lipid nanoparticle compositions |
| TW202446402A (zh) * | 2023-04-12 | 2024-12-01 | 美商艾拉倫製藥公司 | 用於寡核苷酸遞送之調配物 |
| US12311033B2 (en) | 2023-05-31 | 2025-05-27 | Capstan Therapeutics, Inc. | Lipid nanoparticle formulations and compositions |
| WO2025005990A1 (en) * | 2023-06-28 | 2025-01-02 | Global Life Sciences Solutions Canada Ulc | Lipid nanoparticle formulations for cell therapy and related methods |
| WO2025040724A1 (en) * | 2023-08-21 | 2025-02-27 | Global Life Sciences Solutions Canada Ulc | Method and apparatus for ion flux lipid nanoparticle manufacture |
| WO2025061153A1 (en) * | 2023-09-22 | 2025-03-27 | Everest Medicines (China) Co., Ltd. | Rna-lipid particles comprising polysarcosine-lipid conjugate |
| WO2025087303A1 (en) * | 2023-10-24 | 2025-05-01 | Mote Therapeutics Inc. | Lipid nanoparticle with non-covalent bifunctional binders for active targeting |
| WO2025133105A1 (en) * | 2023-12-21 | 2025-06-26 | Biontech Delivery Technologies Gmbh | Compositions and methods |
| WO2025176732A1 (en) | 2024-02-20 | 2025-08-28 | BioNTech SE | Compositions and methods |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102005046490A1 (de) | 2005-09-28 | 2007-03-29 | Johannes-Gutenberg-Universität Mainz | Modifikationen von RNA, die zu einer erhöhten Transkriptstabilität und Translationseffizienz führen |
| WO2016005004A1 (en) | 2014-07-11 | 2016-01-14 | Biontech Rna Pharmaceuticals Gmbh | Stabilization of poly(a) sequence encoding dna sequences |
| WO2016176330A1 (en) | 2015-04-27 | 2016-11-03 | The Trustees Of The University Of Pennsylvania | Nucleoside-modified rna for inducing an adaptive immune response |
| WO2017075531A1 (en) * | 2015-10-28 | 2017-05-04 | Acuitas Therapeutics, Inc. | Novel lipids and lipid nanoparticle formulations for delivery of nucleic acids |
| SMT202100681T1 (it) | 2016-04-22 | 2022-01-10 | BioNTech SE | Procedimenti per fornire rna a singolo filamento |
| EP3468537A1 (en) * | 2016-06-14 | 2019-04-17 | Modernatx, Inc. | Stabilized formulations of lipid nanoparticles |
| US20200163878A1 (en) | 2016-10-26 | 2020-05-28 | Curevac Ag | Lipid nanoparticle mrna vaccines |
| CN113039174B (zh) * | 2018-10-02 | 2023-11-17 | 英特利亚治疗股份有限公司 | 可电离的胺脂质 |
-
2021
- 2021-11-15 EP EP21806755.1A patent/EP4243787A1/en active Pending
- 2021-11-15 US US18/036,681 patent/US20240033344A1/en active Pending
- 2021-11-15 JP JP2023528680A patent/JP2023552678A/ja active Pending
- 2021-11-15 WO PCT/EP2021/081741 patent/WO2022101486A1/en active Application Filing
- 2021-11-15 AU AU2021377746A patent/AU2021377746A1/en active Pending
- 2021-11-15 WO PCT/EP2021/081676 patent/WO2022101471A1/en active Application Filing
- 2021-11-15 CA CA3198309A patent/CA3198309A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPWO2022101486A5 (enrdf_load_stackoverflow) | ||
| WO2022232585A1 (en) | Lyophilization methods for preparing lipid formulated therapeutics | |
| US4769250A (en) | Antracycline antineoplastic agents encapsulated in phospholipid vesicle particles and methods for using same for tumor therapy | |
| CA2992849C (en) | Compositions and methods for nanoparticle lyophile forms | |
| EP0750910A1 (en) | Liposome preparation | |
| BR112020007470A2 (pt) | métodos para produzir um colóide de lipossoma, para preparar partículas, para a fabricação de fluxo contínuo, para preparar uma composição congelada e para preparar uma composição aquosa, colóide de lipossoma, composições, composição congelada e composição aquosa | |
| JP2001522781A (ja) | 共凍結乾燥によるペプチド／脂質複合体の形成 | |
| KR20120086729A (ko) | 젬시타빈 유도체의 비경구적 제제 | |
| CA2155958A1 (en) | Process for preparing liposome composition | |
| CN107427482A (zh) | 凝血酸的多囊脂质体制剂 | |
| JPH09501169A (ja) | 小胞に生体高分子物質を高度に充填する方法 | |
| KR102190157B1 (ko) | 표적화된 기체-충전 미세소포 제형 | |
| CA2376849C (en) | Method of inhibiting leakage of drug encapsulated in liposomes | |
| KR101275837B1 (ko) | 당지질들을 이용하여 지질기반 보강제 제형을 안정화시키기 위한 조성물 및 방법 | |
| WO2024046448A1 (en) | Lyophilized formulations and liquid formulations of lipid nanoparticles | |
| JP2019510048A (ja) | 週１回又は隔週１回の投与に適したリラグルチドの粘弾性ゲル | |
| JP5574965B2 (ja) | 新規タキソイドに基づく組成物 | |
| JPWO2022101470A5 (enrdf_load_stackoverflow) | ||
| HU215960B (hu) | Eljárás hatóanyagot tartalmazó vizes liposzómaszuszpenziók előállítására | |
| US8992969B2 (en) | Biphasic lipid-vesicle compositions and methods for treating cervical dysplasia by intravaginal delivery | |
| US20150044275A1 (en) | Biphasic lipid-vesicle compositions and methods for treating cervical dysplasia by intravaginal delivery | |
| GB2627096A (en) | Bupivacaine multivesicular liposome formulations and uses thereof | |
| Bulbake et al. | Liposomal drug delivery system and its clinically available products | |
| JPWO2022218891A5 (enrdf_load_stackoverflow) | ||
| CN119384272A (zh) | 冻干rna组合物 |