JPWO2022097727A5 - - Google Patents
Download PDFInfo
- Publication number
- JPWO2022097727A5 JPWO2022097727A5 JP2022560831A JP2022560831A JPWO2022097727A5 JP WO2022097727 A5 JPWO2022097727 A5 JP WO2022097727A5 JP 2022560831 A JP2022560831 A JP 2022560831A JP 2022560831 A JP2022560831 A JP 2022560831A JP WO2022097727 A5 JPWO2022097727 A5 JP WO2022097727A5
- Authority
- JP
- Japan
- Prior art keywords
- antisense oligonucleotide
- stranded antisense
- base sequence
- acceptable salt
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020185944 | 2020-11-06 | ||
| PCT/JP2021/040853 WO2022097727A1 (ja) | 2020-11-06 | 2021-11-05 | Ｒｐｓ２５遺伝子の発現及び／又は機能調節剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2022097727A1 JPWO2022097727A1 (https=) | 2022-05-12 |
| JPWO2022097727A5 true JPWO2022097727A5 (https=) | 2023-11-10 |
Family
ID=81458361
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022560831A Pending JPWO2022097727A1 (https=) | 2020-11-06 | 2021-11-05 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20240018516A1 (https=) |
| EP (1) | EP4252846A4 (https=) |
| JP (1) | JPWO2022097727A1 (https=) |
| CN (1) | CN116507727A (https=) |
| TW (1) | TWI910261B (https=) |
| WO (1) | WO2022097727A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4596694A1 (en) * | 2022-09-29 | 2025-08-06 | Institute Of Science Tokyo | Nucleic acid molecule containing 5'-cyclopropylene modification |
| JPWO2024257847A1 (https=) | 2023-06-16 | 2024-12-19 | ||
| WO2025047953A1 (ja) * | 2023-08-30 | 2025-03-06 | 株式会社Stratoimmune | ＲａｓＧＲＰ４のアンチセンスオリゴヌクレオチド |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4236812B2 (ja) | 1997-09-12 | 2009-03-11 | エクシコン エ／エス | オリゴヌクレオチド類似体 |
| US7235358B2 (en) * | 2001-06-08 | 2007-06-26 | Expression Diagnostics, Inc. | Methods and compositions for diagnosing and monitoring transplant rejection |
| JP2012522013A (ja) * | 2009-03-27 | 2012-09-20 | ザ ユーエービー リサーチ ファウンデーション | 調節ｉｒｅｓ媒介翻訳 |
| CA2778171C (en) | 2009-10-29 | 2017-07-25 | Osaka University | Bridged artificial nucleoside and nucleotide |
| US8377901B2 (en) * | 2010-07-07 | 2013-02-19 | The University Of Manitoba | Target host factors for treating viral infection |
| WO2013163404A1 (en) * | 2012-04-27 | 2013-10-31 | The Uab Research Foundation | TREATING VIRAL INFECTIONS HAVING VIRAL RNAs TRANSLATED BY A NON-IRES MEDIATED MECHANISM |
| KR101707437B1 (ko) | 2012-09-21 | 2017-02-16 | 고꾸리쯔 다이가꾸 호우징 오사까 다이가꾸 | 구아니딘 가교를 갖는 인공 뉴클레오시드 및 올리고뉴클레오티드 |
| CN106103463B (zh) | 2014-02-18 | 2018-11-30 | 国立大学法人大阪大学 | 桥连型核苷和核苷酸 |
| CN112501208A (zh) * | 2017-10-03 | 2021-03-16 | 普利维尔治疗公司 | 用于溶酶体障碍的基因疗法 |
| BR112020008033A2 (pt) | 2017-10-23 | 2020-10-27 | Prevail Therapeutics, Inc. | terapias gênicas para doença neurodegenerativa |
| US11725208B2 (en) * | 2017-12-14 | 2023-08-15 | Ionis Pharmaceuticals, Inc. | Conjugated antisense compounds and their use |
| BR112020018902A2 (pt) * | 2018-03-20 | 2021-01-26 | Tokyo Institute Of Technology | oligonucleotídeo antissenso com toxicidade reduzida |
| EP3919501A4 (en) | 2019-02-01 | 2022-11-23 | Osaka University | 5'-MODIFIED NUCLEOSIDE AND NUCLEOTIDE THEREOF |
| WO2020203880A1 (ja) * | 2019-03-29 | 2020-10-08 | 田辺三菱製薬株式会社 | Ｄｕｘ４の発現を調節するための化合物、方法及び医薬組成物 |
| EP4013870A1 (en) * | 2019-08-13 | 2022-06-22 | Alnylam Pharmaceuticals, Inc. | Small ribosomal protein subunit 25 (rps25) irna agent compositions and methods of use thereof |
-
2021
- 2021-11-05 CN CN202180074713.0A patent/CN116507727A/zh active Pending
- 2021-11-05 TW TW110141414A patent/TWI910261B/zh active
- 2021-11-05 JP JP2022560831A patent/JPWO2022097727A1/ja active Pending
- 2021-11-05 EP EP21889279.2A patent/EP4252846A4/en active Pending
- 2021-11-05 US US18/035,300 patent/US20240018516A1/en active Pending
- 2021-11-05 WO PCT/JP2021/040853 patent/WO2022097727A1/ja not_active Ceased
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPWO2022097727A5 (https=) | ||
| CN106167824A (zh) | 与老年性骨质疏松相关微小rna的寡核苷酸化合物的应用 | |
| AU2023222944A1 (en) | Extracellular matrix-producing composition using MAST4 gene and preparation method therefor | |
| EP3845648A1 (en) | Blood-brain barrier permeable aptamer and application thereof | |
| CN108004311B (zh) | 长链非编码rna nonmmut002009及其过表达质粒在诊断和治疗骨骼系统疾病中的应用 | |
| WO2002020036A1 (de) | Arzneimittel mit einer für das rna-bindende koc-protein kodierenden dna-sequenz, einem koc-protein oder einer dna-sequenz des koc-promotors | |
| CN112831463B (zh) | 一种高效诱导脂肪干细胞骨分化的培养基及制备和诱导分化方法及应用 | |
| US20100227318A1 (en) | Method for controlling the amount of gene product, and agent for controlling the amount of gene product | |
| JP3410738B2 (ja) | ミクログリアからなる医薬用キャリアー | |
| KR102466691B1 (ko) | Tsg6 억제제를 포함하는 전이성 고형암 치료용 조성물 | |
| WO2017065563A1 (ko) | Rna 올리고뉴클레오티드를 포함하는 암 치료용 약학 조성물 | |
| Kim et al. | The role of small leucine zipper protein in osteoclastogenesis and its involvement in bone remodeling | |
| KR101431783B1 (ko) | 알츠하이머 모델용 형질전환 개과 동물 및 이의 제조방법 | |
| CN109337907B (zh) | 一种用于抑制TCF12基因的siRNA分子 | |
| CN109224076B (zh) | 与肺癌诊疗相关的基因miR-140-3P及其mimics和应用 | |
| WO2002026977A1 (en) | Host cell obtained by transferring vhl gene into cancer cell or embryonic stem cell and expressing | |
| Zhong et al. | Effect of NF-κB decoy on insulin resistance of adipocytes from patients with type 2 diabetes mellitus | |
| TWI841414B (zh) | 包含外泌體及生物巨分子之組合物、包含其的醫藥組成物及其用途 | |
| JP4387108B2 (ja) | 株化ミクログリア | |
| CN119139373B (zh) | 一种白花地胆草提取物的制药用途 | |
| Bronstein et al. | cDNA cloning and spatiotemporal expression during avian embryogenesis of hnRNP A1, a regulatory factor in alternative splicing | |
| EP1692284B1 (de) | Anti-apoptotisch wirksame apatamere | |
| JP2022524913A (ja) | ヒト細胞間接着分子１（ｉｃａｍ－１）に対するアンチセンス薬 | |
| CN114606232B (zh) | 一种奶牛乳腺炎相关的lncRNA及其应用 | |
| CN110951735B (zh) | 一种长链非编码RNA lnc-PMIF及其小干扰RNA和应用 |