JPWO2022028726A5 - - Google Patents
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- Publication number
- JPWO2022028726A5 JPWO2022028726A5 JP2023507675A JP2023507675A JPWO2022028726A5 JP WO2022028726 A5 JPWO2022028726 A5 JP WO2022028726A5 JP 2023507675 A JP2023507675 A JP 2023507675A JP 2023507675 A JP2023507675 A JP 2023507675A JP WO2022028726 A5 JPWO2022028726 A5 JP WO2022028726A5
- Authority
- JP
- Japan
- Prior art keywords
- imidazol
- tolyl
- isopropyl
- piperidin
- carboxamide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 14
- 238000001816 cooling Methods 0.000 claims 8
- 150000001875 compounds Chemical class 0.000 claims 6
- -1 2-(5-(p-tolyl)-1H-imidazol-2-yl)piperidin-1-yl Chemical group 0.000 claims 4
- DLFVBJFMPXGRIB-UHFFFAOYSA-N Acetamide Chemical compound CC(N)=O DLFVBJFMPXGRIB-UHFFFAOYSA-N 0.000 claims 4
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims 4
- 238000000034 method Methods 0.000 claims 4
- RLYVZCMMEXADQB-UHFFFAOYSA-N n-[4-(2-amino-2-oxoethyl)phenyl]-5-methyl-2-propan-2-ylcyclohexane-1-carboxamide Chemical compound CC(C)C1CCC(C)CC1C(=O)NC1=CC=C(CC(N)=O)C=C1 RLYVZCMMEXADQB-UHFFFAOYSA-N 0.000 claims 4
- 238000009472 formulation Methods 0.000 claims 3
- 239000007788 liquid Substances 0.000 claims 3
- ZIQSNLRVUZTLJR-UHFFFAOYSA-N 1-[2-[5-(4-methylphenyl)-1H-imidazol-2-yl]piperidin-1-yl]-2-methylsulfanylpropan-1-one Chemical compound CSC(C(=O)N1C(CCCC1)C=1NC(=CN=1)C1=CC=C(C=C1)C)C ZIQSNLRVUZTLJR-UHFFFAOYSA-N 0.000 claims 2
- IMQTXOBWDKSYGW-UHFFFAOYSA-N 2-(4-ethylphenoxy)-N-(1H-pyrazol-5-yl)-N-(thiophen-2-ylmethyl)acetamide Chemical compound CCC1=CC=C(OCC(=O)N(CC2=CC=CS2)C2=NNC=C2)C=C1 IMQTXOBWDKSYGW-UHFFFAOYSA-N 0.000 claims 2
- UDSJMKFICGQPCB-UHFFFAOYSA-N CC(C(=O)N1C(CCCC1)C=1NC(=CN=1)C1=CC=C(C=C1)C)(C)SC Chemical compound CC(C(=O)N1C(CCCC1)C=1NC(=CN=1)C1=CC=C(C=C1)C)(C)SC UDSJMKFICGQPCB-UHFFFAOYSA-N 0.000 claims 2
- HMYCSFIQNXBSEW-UHFFFAOYSA-N CC(C(=O)N1C(CCCC1)C=1NC(=CN=1)C1=CC=C(C=C1)C)(C=C)C Chemical compound CC(C(=O)N1C(CCCC1)C=1NC(=CN=1)C1=CC=C(C=C1)C)(C=C)C HMYCSFIQNXBSEW-UHFFFAOYSA-N 0.000 claims 2
- HZOUQFSRYFMEKS-UHFFFAOYSA-N CC(C(=O)N1C(CCCC1)C=1NC(=CN=1)C1=CC=C(C=C1)C)CC Chemical compound CC(C(=O)N1C(CCCC1)C=1NC(=CN=1)C1=CC=C(C=C1)C)CC HZOUQFSRYFMEKS-UHFFFAOYSA-N 0.000 claims 2
- HZOUQFSRYFMEKS-BUSXIPJBSA-N C[C@H](C(=O)N1C(CCCC1)C=1NC(=CN=1)C1=CC=C(C=C1)C)CC Chemical compound C[C@H](C(=O)N1C(CCCC1)C=1NC(=CN=1)C1=CC=C(C=C1)C)CC HZOUQFSRYFMEKS-BUSXIPJBSA-N 0.000 claims 2
- VUNOFAIHSALQQH-UHFFFAOYSA-N Ethyl menthane carboxamide Chemical compound CCNC(=O)C1CC(C)CCC1C(C)C VUNOFAIHSALQQH-UHFFFAOYSA-N 0.000 claims 2
- RWAXQWRDVUOOGG-UHFFFAOYSA-N N,2,3-Trimethyl-2-(1-methylethyl)butanamide Chemical compound CNC(=O)C(C)(C(C)C)C(C)C RWAXQWRDVUOOGG-UHFFFAOYSA-N 0.000 claims 2
- ILXQRAXCLBJOAD-UHFFFAOYSA-N N-(2-hydroxy-2-phenylethyl)-5,5-dimethyl-2-propan-2-ylcyclohexane-1-carboxamide Chemical compound CC(C)C1CCC(C)(C)CC1C(=O)NCC(O)c1ccccc1 ILXQRAXCLBJOAD-UHFFFAOYSA-N 0.000 claims 2
- GWRCTWAPTXBPHW-UHFFFAOYSA-N N-[(Ethoxycarbonyl)methyl)-p-menthane-3-carboxamide Chemical compound CCOC(=O)CNC(=O)C1CC(C)CCC1C(C)C GWRCTWAPTXBPHW-UHFFFAOYSA-N 0.000 claims 2
- PCDHSSHKDZYLLI-UHFFFAOYSA-N butan-1-one Chemical compound CCC[C]=O PCDHSSHKDZYLLI-UHFFFAOYSA-N 0.000 claims 2
- 239000000796 flavoring agent Substances 0.000 claims 2
- 235000019634 flavors Nutrition 0.000 claims 2
- 239000003205 fragrance Substances 0.000 claims 2
- 235000014655 lactic acid Nutrition 0.000 claims 2
- 239000004310 lactic acid Substances 0.000 claims 2
- 239000013543 active substance Substances 0.000 claims 1
- 230000035597 cooling sensation Effects 0.000 claims 1
- 235000003599 food sweetener Nutrition 0.000 claims 1
- 238000002156 mixing Methods 0.000 claims 1
- 210000004400 mucous membrane Anatomy 0.000 claims 1
- 239000003765 sweetening agent Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB2012170.3A GB202012170D0 (en) | 2020-08-05 | 2020-08-05 | Organic compounds |
| GB2012170.3 | 2020-08-05 | ||
| PCT/EP2020/086367 WO2022028726A1 (en) | 2020-08-05 | 2020-12-16 | Cooling sensation compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023536934A JP2023536934A (ja) | 2023-08-30 |
| JPWO2022028726A5 true JPWO2022028726A5 (de) | 2023-12-27 |
Family
ID=72425143
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023507675A Pending JP2023536934A (ja) | 2020-08-05 | 2020-12-16 | 冷却感覚組成物 |
| JP2023507673A Pending JP2023536932A (ja) | 2020-08-05 | 2021-07-28 | 冷却感覚組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023507673A Pending JP2023536932A (ja) | 2020-08-05 | 2021-07-28 | 冷却感覚組成物 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20230310293A1 (de) |
| EP (2) | EP4192422A1 (de) |
| JP (2) | JP2023536934A (de) |
| CN (2) | CN116018128A (de) |
| GB (1) | GB202012170D0 (de) |
| WO (2) | WO2022028726A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB202102676D0 (en) * | 2021-02-25 | 2021-04-14 | Givaudan Sa | Compositions |
| GB202103207D0 (en) * | 2021-03-08 | 2021-04-21 | Givaudan Sa | Organic compounds |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4190643A (en) * | 1971-02-04 | 1980-02-26 | Wilkinson Sword Limited | Compositions having a physiological cooling effect |
| US3988433A (en) | 1973-08-10 | 1976-10-26 | The Procter & Gamble Company | Oral compositions for preventing or removing stains from teeth |
| US4083955A (en) | 1975-04-02 | 1978-04-11 | The Procter & Gamble Company | Processes and compositions for remineralization of dental enamel |
| US4528180A (en) | 1983-03-01 | 1985-07-09 | Schaeffer Hans A | Dental preparation, article and method for storage and delivery thereof |
| US4849213A (en) | 1983-03-01 | 1989-07-18 | Schaeffer Hans A | Dental preparation, article and method for storage and delivery therof |
| US5198220A (en) | 1989-11-17 | 1993-03-30 | The Procter & Gamble Company | Sustained release compositions for treating periodontal disease |
| US5145666A (en) | 1991-10-23 | 1992-09-08 | The Proctor & Gamble Co. | Methods of reducing plaque and gingivitis with reduced staining |
| US5213790A (en) | 1991-10-23 | 1993-05-25 | The Procter & Gamble Co. | Methods of reducing plaque and gingivitis with reduced staining |
| US5281410A (en) | 1991-10-23 | 1994-01-25 | The Proctor & Gamble Company | Methods of reducing plaque and gingivitis with reduced staining |
| US5242910A (en) | 1992-10-13 | 1993-09-07 | The Procter & Gamble Company | Sustained release compositions for treating periodontal disease |
| US7803963B2 (en) * | 2007-10-15 | 2010-09-28 | Millennium Specialty Chemicals, Inc. | Physiological coolants based on lactoyl esters of menthyl lactate |
| DE102008015428A1 (de) * | 2008-03-20 | 2009-09-24 | Beiersdorf Ag | Kühlende Zubereitungen für den humanen Haut- und/oder Schleimhautkontakt mit einem Gehalt an (1R,2S,5R)-2-Isopropyl-5-methyl-N-(2-(pyridin-2-yl)ethyl-cyclohexancarboxamid und/oder (1R,2S,5R)-N-(4-(Cyanomethyl)-phenyl)-2-isopropyl-5-methylcyclohexancarboxamid |
| CA2742823C (en) | 2008-11-20 | 2015-06-16 | The Procter & Gamble Company | Personal care compositions providing enhanced cooling sensation |
| CN110869365B (zh) | 2017-07-14 | 2024-03-29 | 弗门尼舍有限公司 | 清凉组合物 |
-
2020
- 2020-08-05 GB GBGB2012170.3A patent/GB202012170D0/en not_active Ceased
- 2020-12-16 WO PCT/EP2020/086367 patent/WO2022028726A1/en active Application Filing
- 2020-12-16 US US18/005,425 patent/US20230310293A1/en active Pending
- 2020-12-16 JP JP2023507675A patent/JP2023536934A/ja active Pending
- 2020-12-16 EP EP20841891.3A patent/EP4192422A1/de active Pending
- 2020-12-16 CN CN202080104248.6A patent/CN116018128A/zh active Pending
-
2021
- 2021-07-28 US US18/005,404 patent/US20230277427A1/en active Pending
- 2021-07-28 CN CN202180057437.7A patent/CN116096347A/zh active Pending
- 2021-07-28 EP EP21759027.2A patent/EP4192423A1/de active Pending
- 2021-07-28 WO PCT/EP2021/071109 patent/WO2022028976A1/en active Application Filing
- 2021-07-28 JP JP2023507673A patent/JP2023536932A/ja active Pending
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