JPWO2022004760A5 - - Google Patents
Download PDFInfo
- Publication number
- JPWO2022004760A5 JPWO2022004760A5 JP2022534067A JP2022534067A JPWO2022004760A5 JP WO2022004760 A5 JPWO2022004760 A5 JP WO2022004760A5 JP 2022534067 A JP2022534067 A JP 2022534067A JP 2022534067 A JP2022534067 A JP 2022534067A JP WO2022004760 A5 JPWO2022004760 A5 JP WO2022004760A5
- Authority
- JP
- Japan
- Prior art keywords
- tumor
- antibody
- days
- oxaliplatin
- administration group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020112259 | 2020-06-30 | ||
| JP2020196405 | 2020-11-26 | ||
| PCT/JP2021/024651 WO2022004760A1 (ja) | 2020-06-30 | 2021-06-30 | 抗ccr8抗体と化学療法剤の併用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2022004760A1 JPWO2022004760A1 (https=) | 2022-01-06 |
| JPWO2022004760A5 true JPWO2022004760A5 (https=) | 2023-03-16 |
Family
ID=79316496
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022534067A Pending JPWO2022004760A1 (https=) | 2020-06-30 | 2021-06-30 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20230256092A1 (https=) |
| EP (1) | EP4173636A4 (https=) |
| JP (1) | JPWO2022004760A1 (https=) |
| WO (1) | WO2022004760A1 (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111201030B (zh) | 2017-07-25 | 2024-11-01 | 真和制药有限公司 | 通过阻断tim-3和其配体的相互作用治疗癌症 |
| WO2020160156A2 (en) | 2019-01-30 | 2020-08-06 | Immutics, Inc. | Anti-gal3 antibodies and uses thereof |
| TWI890283B (zh) | 2020-02-14 | 2025-07-11 | 美商基利科學股份有限公司 | 結合ccr8之抗體及融合蛋白及其用途 |
| EP4157338A4 (en) | 2020-05-26 | 2024-11-13 | TrueBinding, Inc. | METHOD FOR TREATING INFLAMMATORY DISEASES BY GALECTIN-3 BLOCKING |
| TW202216771A (zh) | 2020-06-26 | 2022-05-01 | 德商拜耳廠股份有限公司 | 用於治療應用之ccr8抗體 |
| JP2024522360A (ja) | 2021-06-04 | 2024-06-18 | アムジエン・インコーポレーテツド | 抗ccr8抗体及びその使用 |
| CN116789820A (zh) * | 2022-03-18 | 2023-09-22 | 北京天诺健成医药科技有限公司 | 一种新型免疫调节剂的开发和应用 |
| US20250243287A1 (en) * | 2022-04-07 | 2025-07-31 | Shenghe (China) Biopharmaceutical Co., Ltd. | Anti-ccr8 antibody or antigen-binding fragment thereof |
| JP2025537137A (ja) * | 2022-11-04 | 2025-11-14 | ギリアード サイエンシーズ, インコーポレイテッド | 抗ccr8抗体、化学療法及び免疫療法の組み合わせを使用する抗がん療法 |
| AU2024247601A1 (en) * | 2023-03-28 | 2025-10-23 | Nb Health Laboratory Co., Ltd. | Antibody, nucleic acid, cell and drug |
| TW202529804A (zh) | 2023-10-06 | 2025-08-01 | 美商安進公司 | 用於癌症治療的組合療法 |
| WO2025145207A1 (en) | 2023-12-29 | 2025-07-03 | Bristol-Myers Squibb Company | Combination therapy of kras inhibitor and treg-depleting agent |
| CN119798438B (zh) * | 2023-12-29 | 2025-11-18 | 广东东阳光药业股份有限公司 | 一种抗ccr8单克隆抗体及其应用 |
| TW202547461A (zh) | 2024-05-17 | 2025-12-16 | 美商銳新醫藥公司 | Ras抑制劑 |
| WO2025255438A1 (en) | 2024-06-07 | 2025-12-11 | Revolution Medicines, Inc. | Methods of treating a ras protein-related disease or disorder |
| WO2025265060A1 (en) | 2024-06-21 | 2025-12-26 | Revolution Medicines, Inc. | Therapeutic compositions and methods for managing treatment-related effects |
| WO2026006747A1 (en) | 2024-06-28 | 2026-01-02 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026015796A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026015801A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026015790A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026015825A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Use of ras inhibitor for treating pancreatic cancer |
| WO2026050446A1 (en) | 2024-08-29 | 2026-03-05 | Revolution Medicines, Inc. | Ras inhibitors |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6214973B1 (en) | 1993-11-19 | 2001-04-10 | Chugai Seiyaku Kabushiki Kaisha | Reshaped human antibody to human medulloblastoma cells |
| DE69535243T2 (de) | 1994-07-13 | 2007-05-10 | Chugai Seiyaku K.K. | Gegen menschliches interleukin-8 gerichteter, rekonstituierter menschlicher antikörper |
| EP0962467A4 (en) | 1996-09-26 | 2002-10-30 | Chugai Pharmaceutical Co Ltd | Antibody against human parathormone related peptides |
| CA2953239A1 (en) | 2000-10-06 | 2002-04-18 | Kyowa Hakko Kirin Co., Ltd. | Antibody composition-producing cell |
| JPWO2005035586A1 (ja) | 2003-10-08 | 2007-11-22 | 協和醗酵工業株式会社 | 融合蛋白質組成物 |
| EP3255060A1 (en) * | 2008-12-09 | 2017-12-13 | F. Hoffmann-La Roche AG | Anti-pd-l1 antibodies and their use to enhance t-cell function |
| PT2769737T (pt) | 2009-07-20 | 2017-06-29 | Bristol Myers Squibb Co | Combinação de um anticorpo anti-ctla4 com etopósido para o tratamento sinérgico de doenças proliferativas |
| AU2014309199B2 (en) | 2013-08-20 | 2018-04-19 | Merck Sharp & Dohme Llc | Treating cancer with a combination of a PD-1 antagonist and dinaciclib |
| JP2017507900A (ja) * | 2013-12-17 | 2017-03-23 | ジェネンテック, インコーポレイテッド | Pd−1軸結合アンタゴニスト及び抗her2抗体を使用してher2陽性がんを治療する方法 |
| PL3102605T3 (pl) | 2014-02-04 | 2019-06-28 | Pfizer Inc. | Połączenie antagonisty pd-1 i inhibitora vegfr do leczenia nowotworu |
| US10087259B1 (en) | 2014-04-28 | 2018-10-02 | Memorial Sloan Kettering Cancer Center | Depleting tumor-specific tregs |
| DK3334457T3 (da) * | 2015-08-10 | 2020-09-21 | Pepmab B V | Humaniserede anti-CCR7-receptorantistoffer |
| WO2018112032A1 (en) | 2016-12-13 | 2018-06-21 | President And Fellows Of Harvard College | Methods and compositions for targeting tumor-infiltrating tregs using inhibitors of ccr8 and tnfrsf8 |
| ES2863412T3 (es) | 2017-03-29 | 2021-10-11 | Shionogi & Co | Composición farmacéutica para el tratamiento del cáncer |
| WO2019157098A1 (en) | 2018-02-06 | 2019-08-15 | Advaxis, Inc. | Compositions comprising a recombinant listeria strain and an anti-ccr8 antibody and methods of use |
| CN110835371A (zh) * | 2018-08-19 | 2020-02-25 | 普米斯生物技术(苏州)有限公司 | 抗ccr8单克隆抗体及其应用 |
| CN110835374A (zh) * | 2018-08-19 | 2020-02-25 | 普米斯生物技术(苏州)有限公司 | 抗ccr8×ctla-4双特异性抗体及其应用 |
| WO2020138489A1 (ja) * | 2018-12-27 | 2020-07-02 | 塩野義製薬株式会社 | 新規抗ccr8抗体 |
| TW202216771A (zh) * | 2020-06-26 | 2022-05-01 | 德商拜耳廠股份有限公司 | 用於治療應用之ccr8抗體 |
-
2021
- 2021-06-30 WO PCT/JP2021/024651 patent/WO2022004760A1/ja not_active Ceased
- 2021-06-30 US US18/014,097 patent/US20230256092A1/en active Pending
- 2021-06-30 JP JP2022534067A patent/JPWO2022004760A1/ja active Pending
- 2021-06-30 EP EP21832297.2A patent/EP4173636A4/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPWO2022004760A5 (https=) | ||
| US10766943B2 (en) | Universal chimeric antigen expressing immune cells for targeting of diverse multiple antigens and method of manufacturing the same and use of the same for treatment of cancer, infections and autoimmune disorders | |
| ES2986343T3 (es) | Anticuerpos contra CLAUDINA-6 y métodos para tratar el cáncer | |
| UA128825C2 (uk) | Гетеродимерні антитіла, що зв'язують enpp3 та cd3 | |
| UA126964C2 (uk) | Конструкція біспецифічного антитіла, що зв'язується з дпб3 (dll3) і кд3 (cd3) | |
| EP3360893B1 (en) | High-affinity and soluble pdl-1 molecule | |
| UA111612C2 (uk) | Домени, які зв'язуються з деімунізованою сироваткою, і їхнє застосування для збільшення часу напівжиття в сироватці | |
| EP3746103A1 (en) | Engineered proteins to enhance sensitivity of a cell to il-2 | |
| Saito et al. | CAR-T cell therapy in AML: recent progress and future perspectives | |
| Getts et al. | Synthetic T cell receptor-based lymphocytes for cancer therapy | |
| JP2018016619A (ja) | Allergin−1アンタゴニストによるがん免疫増強剤 | |
| CN118240093A (zh) | 一种靶向her2与egfr的三特异性t细胞衔接器及其应用 | |
| CN112521513A (zh) | 一种靶向cd19的嵌合抗原受体(car)及其应用 | |
| IL324321A (en) | Multi-receptor natural killer cells | |
| WO2017162185A1 (zh) | 对非小细胞肺癌具有抑制作用的核糖核酸适配体及包含其的药物组合物 | |
| ES2936075T3 (es) | Activador de células T reguladoras, y uso del mismo | |
| Interdonato et al. | BL-01, an Fc-bearing, tetravalent CD20× CD5 bispecific antibody, redirects multiple immune cells to kill tumors in vitro and in vivo | |
| US20230040568A1 (en) | Kir3dl3 is an inhibitory receptor of the immune system and uses thereof | |
| CN116041539B (zh) | Il-2突变体免疫缀合物 | |
| CN119424608A (zh) | Star及包含其的免疫细胞在治疗和预防肿瘤中应用 | |
| CN112457416B (zh) | 一种靶向bcma的嵌合抗原受体(car)及其应用 | |
| WO2020077180A1 (en) | Treatment of immunosuppressed subjects | |
| Smyth et al. | Immunochemotherapy of human colon carcinoma xenografts in nude mice using combinations of idarubicin‐monoclonal antibody conjugates | |
| CN111093703A (zh) | 免疫治疗剂、核苷类抗代谢物和铂类联合在制备治疗肿瘤的药物中的用途 | |
| Jenkins | Generating Protective Cancer Immunity by Allowing Nature to Lead the Way |