JPWO2021230973A5 - - Google Patents
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- Publication number
- JPWO2021230973A5 JPWO2021230973A5 JP2022569149A JP2022569149A JPWO2021230973A5 JP WO2021230973 A5 JPWO2021230973 A5 JP WO2021230973A5 JP 2022569149 A JP2022569149 A JP 2022569149A JP 2022569149 A JP2022569149 A JP 2022569149A JP WO2021230973 A5 JPWO2021230973 A5 JP WO2021230973A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- alkylene
- formula
- aryl
- compound according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 claims description 107
- 125000000217 alkyl group Chemical group 0.000 claims description 28
- 125000003118 aryl group Chemical group 0.000 claims description 18
- 125000000623 heterocyclic group Chemical group 0.000 claims description 14
- 125000005275 alkylenearyl group Chemical group 0.000 claims description 12
- 125000000753 cycloalkyl group Chemical group 0.000 claims description 10
- 125000005218 alkyleneheteroaryl group Chemical group 0.000 claims description 6
- 125000001072 heteroaryl group Chemical group 0.000 claims description 6
- 239000008194 pharmaceutical composition Substances 0.000 claims description 6
- 201000003176 Severe Acute Respiratory Syndrome Diseases 0.000 claims description 5
- -1 carbocycle Chemical group 0.000 claims description 4
- 125000000959 isobutyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])* 0.000 claims description 4
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 claims description 4
- 208000025721 COVID-19 Diseases 0.000 claims description 2
- KXDHJXZQYSOELW-UHFFFAOYSA-M Carbamate Chemical compound NC([O-])=O KXDHJXZQYSOELW-UHFFFAOYSA-M 0.000 claims description 2
- 125000003342 alkenyl group Chemical group 0.000 claims description 2
- 125000004849 alkoxymethyl group Chemical group 0.000 claims description 2
- 125000002877 alkyl aryl group Chemical group 0.000 claims description 2
- 150000001408 amides Chemical class 0.000 claims description 2
- 150000001412 amines Chemical class 0.000 claims description 2
- 239000003937 drug carrier Substances 0.000 claims description 2
- 150000003839 salts Chemical class 0.000 claims description 2
- 125000003107 substituted aryl group Chemical group 0.000 claims description 2
- 125000005346 substituted cycloalkyl group Chemical group 0.000 claims description 2
- 230000001154 acute effect Effects 0.000 description 1
- 230000000241 respiratory effect Effects 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063025775P | 2020-05-15 | 2020-05-15 | |
| US63/025,775 | 2020-05-15 | ||
| US202063120091P | 2020-12-01 | 2020-12-01 | |
| US63/120,091 | 2020-12-01 | ||
| PCT/US2021/022375 WO2021230973A1 (en) | 2020-05-15 | 2021-03-15 | Compounds for the treatment of sars |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023525359A JP2023525359A (ja) | 2023-06-15 |
| JPWO2021230973A5 true JPWO2021230973A5 (https=) | 2024-03-27 |
| JP2023525359A5 JP2023525359A5 (https=) | 2024-03-27 |
Family
ID=78524745
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022569149A Pending JP2023525359A (ja) | 2020-05-15 | 2021-03-15 | Ｓａｒｓの治療のための化合物 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20230192671A1 (https=) |
| EP (1) | EP4149535A4 (https=) |
| JP (1) | JP2023525359A (https=) |
| KR (1) | KR20230012528A (https=) |
| CN (1) | CN116209673A (https=) |
| AU (1) | AU2021270608A1 (https=) |
| BR (1) | BR112022023187A2 (https=) |
| CA (1) | CA3178087A1 (https=) |
| MX (1) | MX2022014303A (https=) |
| WO (1) | WO2021230973A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW202204338A (zh) * | 2020-04-17 | 2022-02-01 | 美商帕迪斯生物科學公司 | 半胱胺酸蛋白酶抑制劑及其使用方法 |
| CN115108970B (zh) * | 2021-03-19 | 2023-08-01 | 四川大学华西医院 | 二酰胺类衍生物及其制药用途 |
| CN117777009A (zh) * | 2022-12-26 | 2024-03-29 | 上海市重大传染病和生物安全研究院 | 化合物达摩克韦及其应用 |
| KR102760691B1 (ko) | 2023-01-31 | 2025-01-24 | 두산에너빌리티 주식회사 | 타이로드 고정 너트 어셈블리 및 이를 포함하는 가스 터빈 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4204002A (en) * | 1974-04-09 | 1980-05-20 | Ciba-Geigy Corporation | Methods of using N-(substituted)-N-alkoxy carbonyl anilino compounds |
| US5274167A (en) * | 1989-01-26 | 1993-12-28 | Bayer Aktiengesellschaft | Polymeriable optically active (meth) acrylic acid derivatives |
| ES2704862T3 (es) * | 2010-07-16 | 2019-03-20 | Agios Pharmaceuticals Inc | Composiciones terapéuticamente activas y su método de uso |
| KR101861869B1 (ko) * | 2013-09-10 | 2018-05-28 | 경희대학교 산학협력단 | 신규한 비스-아미드 유도체 및 이의 용도 |
| US10829440B2 (en) * | 2015-06-12 | 2020-11-10 | Brown University | Antibacterial compounds and methods of making and using same |
| US9975885B2 (en) * | 2016-04-28 | 2018-05-22 | Purdue Research Foundation | Broad-spectrum non-covalent coronavirus protease inhibitors |
| US20200277251A1 (en) * | 2017-06-22 | 2020-09-03 | Brown University | Novel antibacterial compounds and methods of making and using same |
-
2021
- 2021-03-15 US US17/998,909 patent/US20230192671A1/en active Pending
- 2021-03-15 CN CN202180035190.9A patent/CN116209673A/zh active Pending
- 2021-03-15 KR KR1020227043434A patent/KR20230012528A/ko active Pending
- 2021-03-15 WO PCT/US2021/022375 patent/WO2021230973A1/en not_active Ceased
- 2021-03-15 EP EP21803981.6A patent/EP4149535A4/en active Pending
- 2021-03-15 AU AU2021270608A patent/AU2021270608A1/en active Pending
- 2021-03-15 CA CA3178087A patent/CA3178087A1/en active Pending
- 2021-03-15 JP JP2022569149A patent/JP2023525359A/ja active Pending
- 2021-03-15 BR BR112022023187A patent/BR112022023187A2/pt unknown
- 2021-03-15 MX MX2022014303A patent/MX2022014303A/es unknown
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