JPWO2021177397A5 - - Google Patents
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- Publication number
- JPWO2021177397A5 JPWO2021177397A5 JP2022504452A JP2022504452A JPWO2021177397A5 JP WO2021177397 A5 JPWO2021177397 A5 JP WO2021177397A5 JP 2022504452 A JP2022504452 A JP 2022504452A JP 2022504452 A JP2022504452 A JP 2022504452A JP WO2021177397 A5 JPWO2021177397 A5 JP WO2021177397A5
- Authority
- JP
- Japan
- Prior art keywords
- dimethyl
- reducing
- thiohistidine
- ergothioneine
- deleting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000004519 manufacturing process Methods 0.000 claims 9
- SSISHJJTAXXQAX-ZETCQYMHSA-N L-ergothioneine Chemical compound C[N+](C)(C)[C@H](C([O-])=O)CC1=CNC(=S)N1 SSISHJJTAXXQAX-ZETCQYMHSA-N 0.000 claims 5
- 101150040895 metJ gene Proteins 0.000 claims 5
- 238000000034 method Methods 0.000 claims 4
- 241000894006 Bacteria Species 0.000 claims 3
- 238000010362 genome editing Methods 0.000 claims 3
- 230000006801 homologous recombination Effects 0.000 claims 3
- 238000002744 homologous recombination Methods 0.000 claims 3
- 230000035772 mutation Effects 0.000 claims 3
- 238000004040 coloring Methods 0.000 claims 2
- 230000000813 microbial effect Effects 0.000 claims 2
- 230000001580 bacterial effect Effects 0.000 claims 1
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025183259A JP2026021447A (ja) | 2020-03-04 | 2025-10-30 | L-エルゴチオネイン含有組成物 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020036577A JP6864131B1 (ja) | 2020-03-04 | 2020-03-04 | L−エルゴチオネイン含有組成物 |
| PCT/JP2021/008388 WO2021177397A1 (ja) | 2020-03-04 | 2021-03-04 | L-エルゴチオネイン含有組成物 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025183259A Division JP2026021447A (ja) | 2020-03-04 | 2025-10-30 | L-エルゴチオネイン含有組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2021177397A1 JPWO2021177397A1 (https=) | 2021-09-10 |
| JPWO2021177397A5 true JPWO2021177397A5 (https=) | 2024-03-12 |
Family
ID=75638746
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020036577A Active JP6864131B1 (ja) | 2020-03-04 | 2020-03-04 | L−エルゴチオネイン含有組成物 |
| JP2022504452A Pending JPWO2021177397A1 (https=) | 2020-03-04 | 2021-03-04 | |
| JP2025183259A Pending JP2026021447A (ja) | 2020-03-04 | 2025-10-30 | L-エルゴチオネイン含有組成物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020036577A Active JP6864131B1 (ja) | 2020-03-04 | 2020-03-04 | L−エルゴチオネイン含有組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025183259A Pending JP2026021447A (ja) | 2020-03-04 | 2025-10-30 | L-エルゴチオネイン含有組成物 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US12357614B2 (https=) |
| EP (1) | EP4115881A4 (https=) |
| JP (3) | JP6864131B1 (https=) |
| KR (1) | KR20220149718A (https=) |
| CN (1) | CN115209895A (https=) |
| CA (1) | CA3170408A1 (https=) |
| TW (1) | TW202146013A (https=) |
| WO (1) | WO2021177397A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118215476A (zh) * | 2021-11-08 | 2024-06-18 | 三菱瓦斯化学株式会社 | 用于抑制或预防内耳性耳聋的含有麦角硫因的组合物 |
| KR20240127428A (ko) * | 2021-12-23 | 2024-08-22 | 산토리 홀딩스 가부시키가이샤 | 경구 조성물 및 소프트 캡슐제 |
| CN121311472A (zh) * | 2023-06-15 | 2026-01-09 | 长濑产业株式会社 | 化合物或其盐及其制造方法、组合物、过氧化氢清除剂以及细胞毒性抑制剂 |
| WO2025142813A1 (ja) * | 2023-12-27 | 2025-07-03 | サントリーホールディングス株式会社 | 経口組成物 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2707086A1 (fr) * | 1993-06-28 | 1995-01-06 | Bioxytech | Procédé de préparation de l'ergothionéine. |
| DE102004020714A1 (de) * | 2004-04-26 | 2005-11-10 | Beiersdorf Ag | Haut- und/oder Haarmittel enthaltend Verbindungen mit isoprenoider Struktur |
| FR2910808B1 (fr) * | 2006-12-29 | 2009-04-10 | Lvmh Rech | Utilisation en cosmetique de la l-2-thiohistidine ou d'un de ses derives comme agent depigmentant. |
| US7767826B2 (en) | 2007-10-05 | 2010-08-03 | Pharmatech International, Inc. | Process for the synthesis of L-(+)-ergothioneine |
| JP2009126863A (ja) * | 2007-11-27 | 2009-06-11 | Koei Kogyo Kk | キノコから抽出したエルゴチオネインを高含有する組成物 |
| FR2950889B1 (fr) * | 2009-10-06 | 2011-11-18 | Tetrahedron | Procede de synthese de l'ergothioneine et analogues |
| FR2950890B1 (fr) * | 2009-10-06 | 2011-12-30 | Tetrahedron | Procede de synthese de la 2-thiohistidine et analogues |
| AU2013234815B2 (en) | 2012-03-23 | 2017-06-22 | The University Of Queensland | Immunomodulatory agent and uses therefor |
| GB201416678D0 (en) * | 2014-09-22 | 2014-11-05 | Univ Cape Town | Process For Synthesizing Ergothioneine And Its Intermediates |
| EP3252142B1 (en) * | 2015-01-30 | 2021-11-03 | Kikkoman Corporation | Transformed fungus having enhanced ergothioneine productivity and method for producing ergothioneine |
| WO2019089878A1 (en) | 2017-11-02 | 2019-05-09 | Colorado Seminary, Owner and Operator of University of Denver | Methods of treating microbial infection and inflammation |
| US11098330B2 (en) | 2018-02-23 | 2021-08-24 | Nagase & Co., Ltd. | Method for producing ergothioneine |
| JP7185213B2 (ja) * | 2018-03-02 | 2022-12-07 | 国立大学法人 筑波大学 | エルゴチオネイン合成微生物、及びエルゴチオネインの製造方法 |
-
2020
- 2020-03-04 JP JP2020036577A patent/JP6864131B1/ja active Active
-
2021
- 2021-03-04 KR KR1020227033764A patent/KR20220149718A/ko active Pending
- 2021-03-04 WO PCT/JP2021/008388 patent/WO2021177397A1/ja not_active Ceased
- 2021-03-04 JP JP2022504452A patent/JPWO2021177397A1/ja active Pending
- 2021-03-04 TW TW110107636A patent/TW202146013A/zh unknown
- 2021-03-04 CN CN202180018596.6A patent/CN115209895A/zh active Pending
- 2021-03-04 EP EP21764176.0A patent/EP4115881A4/en active Pending
- 2021-03-04 US US17/905,626 patent/US12357614B2/en active Active
- 2021-03-04 CA CA3170408A patent/CA3170408A1/en active Pending
-
2025
- 2025-10-30 JP JP2025183259A patent/JP2026021447A/ja active Pending
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