JPWO2021150894A5 - - Google Patents
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- Publication number
- JPWO2021150894A5 JPWO2021150894A5 JP2022545411A JP2022545411A JPWO2021150894A5 JP WO2021150894 A5 JPWO2021150894 A5 JP WO2021150894A5 JP 2022545411 A JP2022545411 A JP 2022545411A JP 2022545411 A JP2022545411 A JP 2022545411A JP WO2021150894 A5 JPWO2021150894 A5 JP WO2021150894A5
- Authority
- JP
- Japan
- Prior art keywords
- shaft
- endoscope
- injection
- alignment sleeve
- passageway
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000002347 injection Methods 0.000 claims 24
- 239000007924 injection Substances 0.000 claims 24
- 210000003454 tympanic membrane Anatomy 0.000 claims 11
- 238000009472 formulation Methods 0.000 claims 7
- 239000000203 mixture Substances 0.000 claims 7
- 230000001225 therapeutic effect Effects 0.000 claims 7
- 229940121363 anti-inflammatory agent Drugs 0.000 claims 4
- 239000002260 anti-inflammatory agent Substances 0.000 claims 4
- 239000012528 membrane Substances 0.000 claims 4
- 210000003477 cochlea Anatomy 0.000 claims 3
- 238000012986 modification Methods 0.000 claims 3
- 230000004048 modification Effects 0.000 claims 3
- 238000012800 visualization Methods 0.000 claims 3
- 210000000959 ear middle Anatomy 0.000 claims 2
- JYGXADMDTFJGBT-VWUMJDOOSA-N hydrocortisone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 JYGXADMDTFJGBT-VWUMJDOOSA-N 0.000 claims 2
- GZENKSODFLBBHQ-ILSZZQPISA-N Medrysone Chemical compound C([C@@]12C)CC(=O)C=C1[C@@H](C)C[C@@H]1[C@@H]2[C@@H](O)C[C@]2(C)[C@@H](C(C)=O)CC[C@H]21 GZENKSODFLBBHQ-ILSZZQPISA-N 0.000 claims 1
- LRJOMUJRLNCICJ-JZYPGELDSA-N Prednisolone acetate Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@@](C(=O)COC(=O)C)(O)[C@@]1(C)C[C@@H]2O LRJOMUJRLNCICJ-JZYPGELDSA-N 0.000 claims 1
- 229960002537 betamethasone Drugs 0.000 claims 1
- UREBDLICKHMUKA-DVTGEIKXSA-N betamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-DVTGEIKXSA-N 0.000 claims 1
- ALEXXDVDDISNDU-JZYPGELDSA-N cortisol 21-acetate Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@@](C(=O)COC(=O)C)(O)[C@@]1(C)C[C@@H]2O ALEXXDVDDISNDU-JZYPGELDSA-N 0.000 claims 1
- 238000004132 cross linking Methods 0.000 claims 1
- 229960003957 dexamethasone Drugs 0.000 claims 1
- UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 claims 1
- VQODGRNSFPNSQE-CXSFZGCWSA-N dexamethasone phosphate Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)COP(O)(O)=O)(O)[C@@]1(C)C[C@@H]2O VQODGRNSFPNSQE-CXSFZGCWSA-N 0.000 claims 1
- 239000012636 effector Substances 0.000 claims 1
- 229940043075 fluocinolone Drugs 0.000 claims 1
- FEBLZLNTKCEFIT-VSXGLTOVSA-N fluocinolone acetonide Chemical compound C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]2(C)C[C@@H]1O FEBLZLNTKCEFIT-VSXGLTOVSA-N 0.000 claims 1
- -1 fluorometalone Chemical compound 0.000 claims 1
- 229960000890 hydrocortisone Drugs 0.000 claims 1
- 229960001067 hydrocortisone acetate Drugs 0.000 claims 1
- 238000001802 infusion Methods 0.000 claims 1
- 229960001011 medrysone Drugs 0.000 claims 1
- 229960005205 prednisolone Drugs 0.000 claims 1
- OIGNJSKKLXVSLS-VWUMJDOOSA-N prednisolone Chemical compound O=C1C=C[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 OIGNJSKKLXVSLS-VWUMJDOOSA-N 0.000 claims 1
- 229960002800 prednisolone acetate Drugs 0.000 claims 1
- JDOZJEUDSLGTLU-VWUMJDOOSA-N prednisolone phosphate Chemical compound O=C1C=C[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)COP(O)(O)=O)[C@@H]4[C@@H]3CCC2=C1 JDOZJEUDSLGTLU-VWUMJDOOSA-N 0.000 claims 1
- 229960005294 triamcinolone Drugs 0.000 claims 1
- GFNANZIMVAIWHM-OBYCQNJPSA-N triamcinolone Chemical compound O=C1C=C[C@]2(C)[C@@]3(F)[C@@H](O)C[C@](C)([C@@]([C@H](O)C4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 GFNANZIMVAIWHM-OBYCQNJPSA-N 0.000 claims 1
Applications Claiming Priority (19)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062965481P | 2020-01-24 | 2020-01-24 | |
| US62/965,481 | 2020-01-24 | ||
| US202063024183P | 2020-05-13 | 2020-05-13 | |
| US63/024,183 | 2020-05-13 | ||
| US202063040495P | 2020-06-17 | 2020-06-17 | |
| US63/040,495 | 2020-06-17 | ||
| US202063051568P | 2020-07-14 | 2020-07-14 | |
| US63/051,568 | 2020-07-14 | ||
| US202063077448P | 2020-09-11 | 2020-09-11 | |
| US63/077,448 | 2020-09-11 | ||
| US202063078141P | 2020-09-14 | 2020-09-14 | |
| US63/078,141 | 2020-09-14 | ||
| US202063080510P | 2020-09-18 | 2020-09-18 | |
| US63/080,510 | 2020-09-18 | ||
| US202063081015P | 2020-09-21 | 2020-09-21 | |
| US63/081,015 | 2020-09-21 | ||
| US202063082996P | 2020-09-24 | 2020-09-24 | |
| US63/082,996 | 2020-09-24 | ||
| PCT/US2021/014618 WO2021150894A2 (en) | 2020-01-24 | 2021-01-22 | Systems and methods for treating hearing loss |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2023512192A JP2023512192A (ja) | 2023-03-24 |
| JP2023512192A5 JP2023512192A5 (https=) | 2024-01-30 |
| JPWO2021150894A5 true JPWO2021150894A5 (https=) | 2024-01-30 |
| JP7568728B2 JP7568728B2 (ja) | 2024-10-16 |
Family
ID=76969550
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022545410A Active JP7795464B2 (ja) | 2020-01-24 | 2021-01-22 | 耳科のためのデバイス、システム、および方法 |
| JP2022545409A Pending JP2023512989A (ja) | 2020-01-24 | 2021-01-22 | 耳鼻科のためのデバイス、システム、および方法 |
| JP2022545408A Active JP7795463B2 (ja) | 2020-01-24 | 2021-01-22 | 鼓膜を通り中耳および内耳にアクセスするための低侵襲器具および方法 |
| JP2022545412A Active JP7661346B2 (ja) | 2020-01-24 | 2021-01-22 | 外科用顕微鏡システム |
| JP2022545411A Active JP7568728B2 (ja) | 2020-01-24 | 2021-01-22 | 難聴を処置するためのシステムおよび方法 |
| JP2022545415A Active JP7787815B2 (ja) | 2020-01-24 | 2021-01-22 | 耳疾患を処置するためのデバイス、システム、および方法 |
Family Applications Before (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022545410A Active JP7795464B2 (ja) | 2020-01-24 | 2021-01-22 | 耳科のためのデバイス、システム、および方法 |
| JP2022545409A Pending JP2023512989A (ja) | 2020-01-24 | 2021-01-22 | 耳鼻科のためのデバイス、システム、および方法 |
| JP2022545408A Active JP7795463B2 (ja) | 2020-01-24 | 2021-01-22 | 鼓膜を通り中耳および内耳にアクセスするための低侵襲器具および方法 |
| JP2022545412A Active JP7661346B2 (ja) | 2020-01-24 | 2021-01-22 | 外科用顕微鏡システム |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022545415A Active JP7787815B2 (ja) | 2020-01-24 | 2021-01-22 | 耳疾患を処置するためのデバイス、システム、および方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (12) | US11662561B2 (https=) |
| EP (6) | EP4093353A4 (https=) |
| JP (6) | JP7795464B2 (https=) |
| CN (6) | CN115515542B (https=) |
| AU (6) | AU2021211707A1 (https=) |
| CA (6) | CA3165925A1 (https=) |
| WO (6) | WO2021150858A1 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11541215B2 (en) * | 2018-09-25 | 2023-01-03 | Triton Systems, Inc. | Multimodal endoscope and methods of use |
| CN115515542B (zh) | 2020-01-24 | 2026-02-06 | 斯皮拉尔诊疗有限公司 | 用于耳科的装置、系统和方法 |
| WO2022047234A1 (en) * | 2020-08-28 | 2022-03-03 | President And Fellows Of Harvard College | Drug combination kits and methods of drug delivery |
| CN117136086A (zh) * | 2021-04-20 | 2023-11-28 | 科利耳有限公司 | 身体腔室治疗物质递送 |
| US12023278B1 (en) * | 2021-04-24 | 2024-07-02 | Hani Salehi-Had | Devices for performing intraocular surgery and methods for using them |
| WO2023043680A1 (en) * | 2021-09-17 | 2023-03-23 | Boston Scientific Scimed, Inc. | Stent system |
| AU2022358311A1 (en) * | 2021-09-29 | 2024-04-11 | Spiral Therapeutics Inc. | Cochlea injection devices, systems, and methods for otology |
| US20230200637A1 (en) * | 2021-12-29 | 2023-06-29 | Dorna Hakimimehr | Devices and methods for endoscopic neuroablation in the tympanic cavity |
| WO2023147535A2 (en) * | 2022-01-28 | 2023-08-03 | The Trustees Of Columbia University In The City Of New York | Microneedle apparatus and system for perforation of the round window membrane |
| US11679704B1 (en) * | 2022-03-04 | 2023-06-20 | GRA-MAG Truck Interior Systems, L.L.C. | Device and method for setting or removing seat trim |
| WO2024076585A1 (en) * | 2022-10-03 | 2024-04-11 | Kairos Lasers Llc | Therapeutic laser system for activating the tissue stem cell niche for the treatment of medical conditions |
| DE102022135027A1 (de) * | 2022-12-30 | 2024-07-11 | Auriventis Gmbh | Ohrkatheter zur Applikation von Medikamenten |
| CN116098762B (zh) * | 2023-02-06 | 2024-02-20 | 哈尔滨工业大学 | 一种用于耳科手术机器人的内耳注射-采样执行器 |
| WO2024184356A1 (en) * | 2023-03-06 | 2024-09-12 | Institut National de la Santé et de la Recherche Médicale | Miniaturized implants for the inner ear |
| WO2024215539A1 (en) * | 2023-04-11 | 2024-10-17 | Avava, Inc. | Support system for treatment device |
| CN117224207B (zh) * | 2023-09-06 | 2025-04-18 | 中国人民解放军总医院第一医学中心 | 一种可视性鼓膜穿刺针及其使用方法 |
| WO2025188524A1 (en) * | 2024-03-06 | 2025-09-12 | Spiral Therapeutics Inc. | System for treating ear disorders |
| WO2026072803A1 (en) * | 2024-09-26 | 2026-04-02 | Spiral Therapeutics, Inc. | System for accessing a cochlear implant lead insertion site |
Family Cites Families (102)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS55110528A (en) | 1979-02-20 | 1980-08-26 | Olympus Optical Co | Endoscope |
| DE3539009A1 (de) * | 1985-11-02 | 1987-05-07 | Moeller J D Optik | Vorsatz fuer ein stereoskopisches operationsmikroskop fuer die augenchirurgie |
| US4808171A (en) * | 1986-05-16 | 1989-02-28 | Berger Eric S | V-shaped ear ventilation tube |
| DE4114646C2 (de) | 1991-05-04 | 1996-02-29 | Zeiss Carl Fa | Ophthalmoskopie-Vorsatz für ein Operationsmikroskop |
| ES2121021T3 (es) * | 1992-10-23 | 1998-11-16 | Avi Grinblat | Sistema de microscopio estereoscopico optico. |
| US5421818A (en) | 1993-10-18 | 1995-06-06 | Inner Ear Medical Delivery Systems, Inc. | Multi-functional inner ear treatment and diagnostic system |
| US6475138B1 (en) * | 1995-07-12 | 2002-11-05 | Laser Industries Ltd. | Apparatus and method as preparation for performing a myringotomy in a child's ear without the need for anaesthesia |
| US5707383A (en) | 1995-10-05 | 1998-01-13 | Xomed Surgical Products, Inc. | Method of removing soft tissue in the middle ear |
| US5849008A (en) | 1996-04-26 | 1998-12-15 | Anthony; Phillip F. | Method for destruction of the inner ear special sensory epithelium to relieve positional vertigo |
| IT1284973B1 (it) | 1996-10-11 | 1998-05-28 | A R D O Associazione Ricerca E | Uso del sodio 2-mercaptoetansolfonato (mesna) in chirurgia |
| US6045528A (en) | 1997-06-13 | 2000-04-04 | Intraear, Inc. | Inner ear fluid transfer and diagnostic system |
| US6093150A (en) * | 1997-12-31 | 2000-07-25 | Acuson Corporation | Ultrasound otoscope |
| US6205227B1 (en) * | 1998-01-31 | 2001-03-20 | Sarnoff Corporation | Peritympanic hearing instrument |
| US6440102B1 (en) * | 1998-07-23 | 2002-08-27 | Durect Corporation | Fluid transfer and diagnostic system for treating the inner ear |
| US6024726A (en) * | 1998-08-25 | 2000-02-15 | Hill; Frank C | Middle ear fluid aspirator |
| US8197461B1 (en) | 1998-12-04 | 2012-06-12 | Durect Corporation | Controlled release system for delivering therapeutic agents into the inner ear |
| US6277148B1 (en) * | 1999-02-11 | 2001-08-21 | Soundtec, Inc. | Middle ear magnet implant, attachment device and method, and test instrument and method |
| US6120484A (en) | 1999-02-17 | 2000-09-19 | Silverstein; Herbert | Otological implant for delivery of medicament and method of using same |
| US9089450B2 (en) * | 2000-11-14 | 2015-07-28 | Cochlear Limited | Implantatable component having an accessible lumen and a drug release capsule for introduction into same |
| AU2002238300B2 (en) * | 2001-03-19 | 2007-07-12 | Cochlear Limited | Insertion tool system for an electrode array |
| US20040181185A1 (en) * | 2003-03-14 | 2004-09-16 | Yi-Chang Lee | Device for removing diseased surface tissues |
| US6770080B2 (en) | 2001-04-26 | 2004-08-03 | Fenestra Medical, Inc. | Mechanically registered videoscopic myringotomy/tympanostomy tube placement system |
| WO2002102278A2 (en) | 2001-06-18 | 2002-12-27 | Durect Corporation | Device and method for delivering microdoses of agent to the ear |
| US6648873B2 (en) | 2001-09-21 | 2003-11-18 | Durect Corp. | Aural catheter system including anchor balloon and balloon inflation device |
| AU2002363103B2 (en) * | 2001-10-24 | 2008-10-16 | Med-El Elektromedizinische Gerate Ges.M.B.H. | Implantable fluid delivery apparatuses and implantable electrode |
| US7179238B2 (en) * | 2002-05-21 | 2007-02-20 | Medtronic Xomed, Inc. | Apparatus and methods for directly displacing the partition between the middle ear and inner ear at an infrasonic frequency |
| US20040133099A1 (en) * | 2002-12-18 | 2004-07-08 | Dyer R. Kent | Otologic nanotechnology |
| DE10316242A1 (de) * | 2003-04-09 | 2004-10-28 | Carl Zeiss | Umlenksystem für eine Beobachtungseinrichtung sowie Beobachtungseinrichtung |
| US7399275B2 (en) | 2003-07-28 | 2008-07-15 | Welch Allyn, Inc. | Otoscope |
| US7351246B2 (en) | 2004-01-20 | 2008-04-01 | Epley John M | Minimally invasive, sustained, intra-tympanic drug delivery system |
| US20070167682A1 (en) * | 2004-04-21 | 2007-07-19 | Acclarent, Inc. | Endoscopic methods and devices for transnasal procedures |
| US20070264296A1 (en) * | 2006-05-10 | 2007-11-15 | Myntti Matthew F | Biofilm extracellular polysachharide solvating system |
| US7976873B2 (en) | 2006-05-10 | 2011-07-12 | Medtronic Xomed, Inc. | Extracellular polysaccharide solvating system for treatment of bacterial ear conditions |
| RU59408U1 (ru) * | 2006-08-28 | 2006-12-27 | Иван Васильевич Агеенко | Устройство для исследования и лечения заболеваний среднего уха |
| JP4238905B2 (ja) * | 2006-09-05 | 2009-03-18 | 久郎 藤原 | 鼓膜ドレーンチューブ |
| WO2008036368A2 (en) * | 2006-09-20 | 2008-03-27 | University Of Virginia Patent Foundation | Tube, stent and collar insertion device |
| US9289266B2 (en) * | 2006-12-01 | 2016-03-22 | Boston Scientific Scimed, Inc. | On-axis drive systems and methods |
| WO2008079476A2 (en) * | 2006-12-21 | 2008-07-03 | Choi George Y | Eustachian tube treatment systems |
| US20080167527A1 (en) | 2007-01-09 | 2008-07-10 | Slenker Dale E | Surgical systems and methods for biofilm removal, including a sheath for use therewith |
| US8088095B2 (en) * | 2007-02-08 | 2012-01-03 | Medtronic Xomed, Inc. | Polymeric sealant for medical use |
| CA2676081C (en) * | 2007-02-08 | 2015-07-07 | Medtronic Xomed, Inc. | Solvating system and sealant for medical use |
| US8425488B2 (en) * | 2007-04-19 | 2013-04-23 | Acclarent, Inc. | System and method for the simultaneous bilateral treatment of target tissues within the ears using a guide block structure |
| US20100198191A1 (en) | 2007-12-20 | 2010-08-05 | Acclarent, Inc. | Method and system for treating target tissue within the eustachian tube |
| US20090270894A1 (en) * | 2008-04-25 | 2009-10-29 | Joshua David Rubin | Surgical instrument with internal irrigation |
| PT104131B (pt) * | 2008-07-14 | 2010-10-20 | Univ Do Porto | Dispositivo para a medição e análise da cor do ouvido externo e canal auditivo |
| US8945142B2 (en) * | 2008-08-27 | 2015-02-03 | Cook Medical Technologies Llc | Delivery system for implanting nasal ventilation tube |
| CN102186528B (zh) | 2008-10-15 | 2013-08-07 | Med-El电气医疗器械有限公司 | 内耳给药装置 |
| US8401214B2 (en) * | 2009-06-18 | 2013-03-19 | Earlens Corporation | Eardrum implantable devices for hearing systems and methods |
| BR112012002134B8 (pt) | 2009-07-30 | 2021-05-25 | Salvat Lab Sa | compostos inibidores de apaf-1 |
| EP2488238A2 (en) | 2009-10-15 | 2012-08-22 | Entratympanic, LLC | Device and method for delivering medicine into the tympanic cavity |
| US8685052B2 (en) | 2010-06-30 | 2014-04-01 | Laurimed, Llc | Devices and methods for cutting tissue |
| WO2012094666A1 (en) * | 2011-01-07 | 2012-07-12 | Preceptis Medical, Inc. | Stabilization system and aspiration device with protected cutting edge |
| WO2013022772A1 (en) | 2011-08-05 | 2013-02-14 | Unitract Syringe Pty Ltd | Cannula with controlled depth of insertion |
| CN102429630B (zh) * | 2011-08-10 | 2013-08-14 | 长春德信光电技术有限公司 | 一种基于数码成像的半导体激光耳镜装置 |
| US20130060131A1 (en) * | 2011-09-02 | 2013-03-07 | The Texas A&M University System | Method and apparatus for examining inner ear |
| WO2013036454A1 (en) * | 2011-09-08 | 2013-03-14 | Entrigue Surgical, Inc. | Systems, devices and methods for providing therapy to an anatomical structure |
| US10130514B2 (en) * | 2011-09-26 | 2018-11-20 | Incube Labs, Llc | System and method for delivery of a therapeutic agent to the inner ear |
| US20130245569A1 (en) | 2012-03-15 | 2013-09-19 | Med-El Elektromedizinische Geraete Gmbh | Accessory Device for Inner Ear Drug Delivery |
| US9198560B2 (en) * | 2012-03-19 | 2015-12-01 | Welch Allyn, Inc. | Medical diagnostic instrument |
| US20130274715A1 (en) | 2012-04-13 | 2013-10-17 | Acclarent, Inc. | Method and System for Eustachian Tube Dilation |
| WO2014052595A2 (en) | 2012-09-26 | 2014-04-03 | University Of Virginia | Devices and methods for protecting an internal channel of a subject |
| CA2890730C (en) * | 2012-11-15 | 2019-12-31 | Cork Institute Of Technology | Tympanostomy tube and insertion device |
| US10821276B2 (en) * | 2012-12-14 | 2020-11-03 | The Trustees Of Columbia University In The City Of New York | System and method to locally deliver therapeutic agent to inner ear |
| CA2932540A1 (en) * | 2012-12-14 | 2014-06-19 | The Trustees Of Columbia University In The City Of New York | System and method to locally deliver therapeutic agent to inner ear |
| US9629684B2 (en) * | 2013-03-15 | 2017-04-25 | Acclarent, Inc. | Apparatus and method for treatment of ethmoid sinusitis |
| US10398463B2 (en) * | 2013-06-28 | 2019-09-03 | Misonix Incorporated | Ultrasonic instrument and method for manufacturing same |
| US20150151095A1 (en) * | 2013-11-29 | 2015-06-04 | Muaaz Tarabichi | Combined balloon dilation catheter and introducer for dilation of eustachian tube |
| US9616207B2 (en) | 2014-06-26 | 2017-04-11 | Cochlear Limited | Treatment of the ear |
| CA2956793A1 (en) | 2014-06-27 | 2015-12-30 | The Trustees Of Columbia University In The City Of New York | Apparatus for perforation and aspiration of inner ear |
| JP5908195B1 (ja) * | 2014-06-30 | 2016-04-26 | オリンパス株式会社 | 穿刺用処置具 |
| US9833360B2 (en) | 2014-08-12 | 2017-12-05 | Tusker Medical, Inc. | Tympanostomy tube delivery device with replaceable shaft portion |
| US20160346511A1 (en) | 2015-06-01 | 2016-12-01 | Webb Medical LLC | Middle ear surgical attachments for suction catheters and suction catheters including the same |
| WO2017049000A1 (en) * | 2015-09-15 | 2017-03-23 | Massachusetts Institute Of Technology | Systems and methods for diagnosis of middle ear conditions and detection of analytes in the tympanic membrane |
| WO2017046779A1 (en) * | 2015-09-17 | 2017-03-23 | Tymcure Ltd | Tympanoplastic patch applicator |
| US10098529B2 (en) * | 2015-10-28 | 2018-10-16 | Ricoh Company, Ltd. | Optical design of a light field otoscope |
| US10070993B2 (en) * | 2015-10-30 | 2018-09-11 | Acclarent, Inc. | System and method for treatment of eustachian tube from middle ear approach |
| US20170239091A1 (en) * | 2016-02-22 | 2017-08-24 | Altek Corporation | Eardrum incision device |
| WO2017152061A1 (en) | 2016-03-04 | 2017-09-08 | Aerin Medical, Inc. | Eustachian tube modification |
| JP6855074B2 (ja) | 2016-03-31 | 2021-04-07 | 国立大学法人東北大学 | 長尺状の医療器具の保持機構 |
| CN205964003U (zh) * | 2016-06-13 | 2017-02-22 | 苗旭涛 | 一种电耳镜及配套的耳窥镜和穿刺针 |
| JP2019522539A (ja) | 2016-06-22 | 2019-08-15 | ザ チャールズ スターク ドレイパー ラボラトリー， インク．Ｔｈｅ Ｃｈａｒｌｅｓ Ｓｔａｒｋ Ｄｒａｐｅｒ Ｌａｂｏｒａｔｏｒｙ， Ｉｎｃ． | 経正円窓膜注入による内耳薬物送達用のシステム |
| EP3478356B1 (en) * | 2016-07-03 | 2023-09-06 | Sinusafe Medical Ltd | Medical device for treatment of a sinus and/or an ear |
| JP2019527571A (ja) | 2016-08-05 | 2019-10-03 | タスカー メディカル，インコーポレイテッド | 治療物質を中耳及び／又は内耳へ送達するためのシステム、装置及び方法 |
| SG11201909114XA (en) * | 2017-04-20 | 2019-11-28 | Resnent Llc | Flexible-rigid hybrid endoscope and instrument attachments |
| WO2019016613A2 (en) | 2017-07-17 | 2019-01-24 | 3Nt Medical Ltd. | EAR VISUALIZATION SYSTEM |
| CN115569000A (zh) | 2017-09-26 | 2023-01-06 | 延世大学校原州产学协力团 | 中耳炎治疗仪 |
| ES3015034T3 (en) | 2017-11-02 | 2025-04-28 | Aventamed Designated Activity Company | A placement device |
| GB2569325B (en) | 2017-12-13 | 2020-05-06 | Imperial Innovations Ltd | Ear examination apparatus |
| US11806493B2 (en) | 2018-02-02 | 2023-11-07 | Tusker Medical, Inc. | Systems, apparatus, and methods for transport and delivery of therapeutic substance to middle ear |
| EP3773381B1 (en) * | 2018-04-13 | 2024-07-03 | Stryker European Operations Holdings LLC | Systems of performing transcanal ear surgery |
| WO2019200529A1 (zh) | 2018-04-17 | 2019-10-24 | 深圳市汇顶科技股份有限公司 | 图像处理方法、装置和电子设备 |
| AU2019256527B2 (en) | 2018-04-19 | 2025-01-23 | Spiral Therapeutics, Inc. | Inner ear drug delivery devices and methods of use |
| WO2019209690A1 (en) * | 2018-04-23 | 2019-10-31 | Med-El Elektromedizinische Geraete Gmbh | Patient specific adjustment of cochlear implant insertion trajectories |
| CA3098625C (en) * | 2018-05-18 | 2022-12-06 | Vascular Technology, Incorporated | Articulating microsurgical instrument |
| US11801362B2 (en) * | 2018-05-21 | 2023-10-31 | The Texas A&M University System | Surgical cannulas and related methods |
| US11559673B2 (en) * | 2018-06-22 | 2023-01-24 | Acclarent, Inc. | Multi-balloon instrument for dilating eustachian tube via middle ear |
| US11541215B2 (en) | 2018-09-25 | 2023-01-03 | Triton Systems, Inc. | Multimodal endoscope and methods of use |
| US20220032020A1 (en) | 2018-12-05 | 2022-02-03 | Cochlear Limited | Therapeutic substance storage and delivery |
| US10492670B1 (en) | 2018-12-18 | 2019-12-03 | 3Nt Medical Ltd. | Ear visualization and treatment system |
| TWI797392B (zh) * | 2019-11-05 | 2023-04-01 | 國防醫學院 | 微氣泡間接以力學波促進藥物傳遞的方法 |
| KR102793995B1 (ko) * | 2020-01-13 | 2025-04-14 | 삼성디스플레이 주식회사 | 유기 발광 표시 장치 |
| CN115515542B (zh) | 2020-01-24 | 2026-02-06 | 斯皮拉尔诊疗有限公司 | 用于耳科的装置、系统和方法 |
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