JPWO2021041373A5 - - Google Patents
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- JPWO2021041373A5 JPWO2021041373A5 JP2022513859A JP2022513859A JPWO2021041373A5 JP WO2021041373 A5 JPWO2021041373 A5 JP WO2021041373A5 JP 2022513859 A JP2022513859 A JP 2022513859A JP 2022513859 A JP2022513859 A JP 2022513859A JP WO2021041373 A5 JPWO2021041373 A5 JP WO2021041373A5
- Authority
- JP
- Japan
- Prior art keywords
- expression vector
- pharmaceutical composition
- seq
- cells
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962891799P | 2019-08-26 | 2019-08-26 | |
US62/891,799 | 2019-08-26 | ||
US201962902352P | 2019-09-18 | 2019-09-18 | |
US62/902,352 | 2019-09-18 | ||
US202063004258P | 2020-04-02 | 2020-04-02 | |
US63/004,258 | 2020-04-02 | ||
PCT/US2020/047733 WO2021041373A1 (en) | 2019-08-26 | 2020-08-25 | Treatment of diabetic retinopathy with fully-human post-translationally modified anti-vegf fab |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2022545967A JP2022545967A (ja) | 2022-11-01 |
JPWO2021041373A5 true JPWO2021041373A5 (xx) | 2023-09-01 |
Family
ID=72473961
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2022513859A Pending JP2022545967A (ja) | 2019-08-26 | 2020-08-25 | 完全ヒト翻訳後修飾抗VEGF Fabを用いる糖尿病性網膜症の処置 |
Country Status (12)
Country | Link |
---|---|
US (1) | US20220280608A1 (xx) |
EP (1) | EP4021936A1 (xx) |
JP (1) | JP2022545967A (xx) |
KR (1) | KR20220051246A (xx) |
CN (1) | CN114502197A (xx) |
AU (1) | AU2020336314A1 (xx) |
BR (1) | BR112022003811A2 (xx) |
CA (1) | CA3149401A1 (xx) |
IL (1) | IL290863A (xx) |
MX (1) | MX2022002366A (xx) |
TW (1) | TW202122419A (xx) |
WO (1) | WO2021041373A1 (xx) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SG11202005618WA (en) | 2017-12-19 | 2020-07-29 | Akouos Inc | Aav-mediated delivery of therapeutic antibodies to the inner ear |
WO2024073669A1 (en) | 2022-09-30 | 2024-04-04 | Regenxbio Inc. | Treatment of ocular diseases with recombinant viral vectors encoding anti-vegf fab |
Family Cites Families (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CZ206195A3 (en) | 1993-02-12 | 1996-04-17 | Univ Leland Stanford Junior | Controlled transcription of target genes and other biological materials |
JP3817739B2 (ja) | 1994-12-29 | 2006-09-06 | マサチューセッツ・インスティテュート・オブ・テクノロジー | キメラdna結合性タンパク質 |
KR19990022651A (ko) | 1995-06-07 | 1999-03-25 | 데이비드 엘. 버스테인 | 생물학적 사건에 대한 라파마이신 기재 조절방법 |
CA2300376A1 (en) | 1997-08-26 | 1999-03-04 | Ariad Gene Therapeutics, Inc. | Fusion proteins comprising a dimerization, trimerization or tetramerization domain and an additional heterologous transcription activation, transcription repression, dna binding or ligand binding domain |
IL134643A0 (en) | 1997-08-27 | 2001-04-30 | Ariad Gene Therapeutics Inc | Chimeric transcriptional activators and compositions and uses related thereto |
EP1045915A2 (en) | 1998-01-15 | 2000-10-25 | Ariad Gene Therapeutics, Inc. | Regulation of biological events using multimeric chimeric proteins |
EP1053241A1 (en) | 1998-02-13 | 2000-11-22 | President And Fellows Of Harvard College | Novel dimerizing agents, their production and use |
JP4827353B2 (ja) | 1999-08-09 | 2011-11-30 | ターゲティッド ジェネティクス コーポレイション | 鎖内塩基対を形成するような配列の設計による、組換えウイルスベクターからの一本鎖の異種ヌクレオチド配列の発現の増大 |
US7067526B1 (en) | 1999-08-24 | 2006-06-27 | Ariad Gene Therapeutics, Inc. | 28-epirapalogs |
SG157224A1 (en) | 2001-11-13 | 2009-12-29 | Univ Pennsylvania | A method of detecting and/or identifying adeno-associated virus (aav) sequences and isolating novel sequences identified thereby |
EP1453547B1 (en) | 2001-12-17 | 2016-09-21 | The Trustees Of The University Of Pennsylvania | Adeno-associated virus (aav) serotype 8 sequences, vectors containing same, and uses therefor |
DK3211085T3 (da) | 2003-09-30 | 2021-06-21 | Univ Pennsylvania | Klader af adeno-associeret virus (aav), sekvenser, vektorer indeholdende disse og anvendelser deraf |
DK2359867T3 (en) | 2005-04-07 | 2015-01-05 | Univ Pennsylvania | A method for increasing an AAV vector function |
EP1777906A1 (en) | 2005-06-09 | 2007-04-25 | Matsushita Electric Industrial Co., Ltd. | Amplitude error compensating apparatus and orthogonality error compensating apparatus |
US8734809B2 (en) | 2009-05-28 | 2014-05-27 | University Of Massachusetts | AAV's and uses thereof |
US8927514B2 (en) | 2010-04-30 | 2015-01-06 | City Of Hope | Recombinant adeno-associated vectors for targeted treatment |
US8628966B2 (en) | 2010-04-30 | 2014-01-14 | City Of Hope | CD34-derived recombinant adeno-associated vectors for stem cell transduction and systemic therapeutic gene transfer |
WO2012057363A1 (ja) | 2010-10-27 | 2012-05-03 | 学校法人自治医科大学 | 神経系細胞への遺伝子導入のためのアデノ随伴ウイルスビリオン |
JP6042825B2 (ja) | 2011-02-10 | 2016-12-14 | ザ・ユニヴァーシティ・オヴ・ノース・キャロライナ・アト・チャペル・ヒル | 改変された形質導入プロファイルを有するウイルスベクターならびにその製造および使用の方法 |
EP3693025B1 (en) | 2011-04-22 | 2021-10-13 | The Regents of The University of California | Adeno-associated virus virions with variant capsid and methods of use thereof |
EP2748185A1 (en) | 2011-08-24 | 2014-07-02 | The Board of Trustees of The Leland Stanford Junior University | New aav capsid proteins for nucleic acid transfer |
US9677088B2 (en) | 2012-05-09 | 2017-06-13 | Oregon Health & Science University | Adeno associated virus plasmids and vectors |
ES2729166T3 (es) | 2012-05-24 | 2019-10-30 | Altaviz Llc | Inyector de fluido viscoso |
JP2016514152A (ja) | 2013-03-13 | 2016-05-19 | ザ・チルドレンズ・ホスピタル・オブ・フィラデルフィア | アデノ随伴ウイルスベクターおよびその使用の方法 |
EP3044318B1 (en) | 2013-09-13 | 2019-05-01 | California Institute of Technology | Selective recovery |
CN115141260A (zh) | 2013-10-11 | 2022-10-04 | 马萨诸塞眼科耳科诊所 | 预测祖先病毒序列的方法及其用途 |
US10746742B2 (en) | 2014-04-25 | 2020-08-18 | Oregon Health & Science University | Methods of viral neutralizing antibody epitope mapping |
US10064752B2 (en) | 2014-09-11 | 2018-09-04 | Orbit Biomedical Limited | Motorized suprachoroidal injection of therapeutic agent |
EP3223760B1 (en) | 2014-11-28 | 2020-01-08 | Visionisti OY | Ocular therapeutics tool |
USD878575S1 (en) | 2015-11-24 | 2020-03-17 | Visionisti Oy | Hand operated medical instrument |
SG10202008378UA (en) | 2016-04-15 | 2020-10-29 | Regenxbio Inc | Treatment of ocular diseases with fully-human post-translationally modified anti-vegf fab |
SG11201808426XA (en) | 2016-04-15 | 2018-10-30 | Univ Pennsylvania | Compositions for treatment of wet age-related macular degeneration |
CA3076905A1 (en) | 2017-09-27 | 2019-04-04 | The Johns Hopkins University | Treatment of ocular diseases with fully-human post-translationally modified anti-vegf fab |
CA3079565A1 (en) * | 2017-10-18 | 2019-04-25 | Regenxbio Inc. | Treatment of ocular diseases and metastatic colon cancer with human post-translationally modified vegf-trap |
EP3703792B1 (en) | 2017-11-04 | 2023-10-11 | Altaviz, LLC | Injection devices and methods for making them |
US10912883B2 (en) | 2017-11-04 | 2021-02-09 | Altaviz, Llc | Gas-powered fluid injection system |
-
2020
- 2020-08-25 JP JP2022513859A patent/JP2022545967A/ja active Pending
- 2020-08-25 AU AU2020336314A patent/AU2020336314A1/en active Pending
- 2020-08-25 CA CA3149401A patent/CA3149401A1/en active Pending
- 2020-08-25 BR BR112022003811A patent/BR112022003811A2/pt unknown
- 2020-08-25 WO PCT/US2020/047733 patent/WO2021041373A1/en active Application Filing
- 2020-08-25 MX MX2022002366A patent/MX2022002366A/es unknown
- 2020-08-25 KR KR1020227009810A patent/KR20220051246A/ko unknown
- 2020-08-25 US US17/638,517 patent/US20220280608A1/en active Pending
- 2020-08-25 TW TW109129003A patent/TW202122419A/zh unknown
- 2020-08-25 CN CN202080070135.9A patent/CN114502197A/zh active Pending
- 2020-08-25 EP EP20771671.3A patent/EP4021936A1/en active Pending
-
2022
- 2022-02-24 IL IL290863A patent/IL290863A/en unknown
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