JPWO2021033530A1 - - Google Patents
Info
- Publication number
- JPWO2021033530A1 JPWO2021033530A1 JP2021540709A JP2021540709A JPWO2021033530A1 JP WO2021033530 A1 JPWO2021033530 A1 JP WO2021033530A1 JP 2021540709 A JP2021540709 A JP 2021540709A JP 2021540709 A JP2021540709 A JP 2021540709A JP WO2021033530 A1 JPWO2021033530 A1 JP WO2021033530A1
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/002—Heterocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/004—Acyclic, carbocyclic or heterocyclic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur, selenium or tellurium
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F19/00—Metal compounds according to more than one of main groups C07F1/00 - C07F17/00
- C07F19/005—Metal compounds according to more than one of main groups C07F1/00 - C07F17/00 without metal-C linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/003—Compounds containing elements of Groups 4 or 14 of the Periodic Table without C-Metal linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025085833A JP2025116040A (ja) | 2019-08-21 | 2025-05-22 | 放射性金属錯体の製造方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019151480 | 2019-08-21 | ||
| JP2019151480 | 2019-08-21 | ||
| PCT/JP2020/029757 WO2021033530A1 (ja) | 2019-08-21 | 2020-08-04 | 放射性金属錯体の製造方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025085833A Division JP2025116040A (ja) | 2019-08-21 | 2025-05-22 | 放射性金属錯体の製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2021033530A1 true JPWO2021033530A1 (https=) | 2021-02-25 |
| JP7744828B2 JP7744828B2 (ja) | 2025-09-26 |
Family
ID=74660922
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021540709A Active JP7744828B2 (ja) | 2019-08-21 | 2020-08-04 | 放射性金属錯体の製造方法 |
| JP2025085833A Pending JP2025116040A (ja) | 2019-08-21 | 2025-05-22 | 放射性金属錯体の製造方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025085833A Pending JP2025116040A (ja) | 2019-08-21 | 2025-05-22 | 放射性金属錯体の製造方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20220259160A1 (https=) |
| EP (1) | EP4019502A4 (https=) |
| JP (2) | JP7744828B2 (https=) |
| KR (1) | KR20220047974A (https=) |
| CN (1) | CN114269724A (https=) |
| AU (1) | AU2020332618A1 (https=) |
| CA (1) | CA3148288A1 (https=) |
| TW (1) | TW202120483A (https=) |
| WO (1) | WO2021033530A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022149578A1 (ja) | 2021-01-08 | 2022-07-14 | 日本メジフィジックス株式会社 | Ａｃ－２２５溶液の製造方法およびＡｃ－２２５溶液を用いた医薬の製造方法 |
| EP4442285A1 (en) | 2021-11-30 | 2024-10-09 | Nihon Medi-Physics Co., Ltd. | Stabilized radiopharmaceutical composition |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004532820A (ja) * | 2001-02-28 | 2004-10-28 | ダウ グローバル テクノロジーズ インコーポレイティド | 標的放射線療法のためのアクチニウム−２２５錯体および複合体 |
| JP2007535492A (ja) * | 2003-12-01 | 2007-12-06 | イムノメディクス， インコーポレイテッド | タンパク質とキレート剤とのコンジュゲートを調製するための改良された方法 |
| JP2017503763A (ja) * | 2013-12-03 | 2017-02-02 | ミレニアム ファーマシューティカルズ， インコーポレイテッドＭｉｌｌｅｎｎｉｕｍ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． | Ｇｃｃ発現細胞を撮像するための化合物及び組成物 |
| WO2018187631A1 (en) * | 2017-04-05 | 2018-10-11 | Cornell University | Trifunctional constructs with tunable pharmacokinetics useful in imaging and anti-tumor therapies |
| WO2021019983A1 (ja) * | 2019-07-30 | 2021-02-04 | Ｊｆｅエンジニアリング株式会社 | ジルコニウム錯体の合成方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7597876B2 (en) * | 2007-01-11 | 2009-10-06 | Immunomedics, Inc. | Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules |
| WO2008009444A1 (en) * | 2006-07-19 | 2008-01-24 | Van Dulmen, Adrianus, A. | Use of ethanol for stabilizing a single-vial liquid formulation of a radiolabeled peptide |
| AU2010326004B2 (en) * | 2009-12-04 | 2016-04-21 | Immunomedics, Inc. | Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules |
| DE102012019714B4 (de) * | 2012-10-08 | 2022-04-28 | Johannes Gutenberg-Universität Mainz | Verfahren zur Herstellung von pharmakologischen Metall-Ligand-Konjugaten |
| US20140147381A1 (en) * | 2012-11-29 | 2014-05-29 | Gregory David Espenan | 89zr compounds, to include somatostatin, apparatus and products comprising such compounds, methods of making same, and methods of using same for radio imaging and/or treatment |
| WO2017161356A1 (en) * | 2016-03-18 | 2017-09-21 | Wake Forest University | Compounds, compositions and associated methods using zirconium-89 in immuno-positron emission tomography |
| JP2019151480A (ja) | 2018-03-06 | 2019-09-12 | 富士ゼロックス株式会社 | 検知装置及び画像形成装置 |
-
2020
- 2020-08-04 CA CA3148288A patent/CA3148288A1/en active Pending
- 2020-08-04 US US17/632,994 patent/US20220259160A1/en active Pending
- 2020-08-04 AU AU2020332618A patent/AU2020332618A1/en active Pending
- 2020-08-04 KR KR1020227004086A patent/KR20220047974A/ko not_active Ceased
- 2020-08-04 EP EP20855145.7A patent/EP4019502A4/en active Pending
- 2020-08-04 WO PCT/JP2020/029757 patent/WO2021033530A1/ja not_active Ceased
- 2020-08-04 CN CN202080058291.3A patent/CN114269724A/zh active Pending
- 2020-08-04 JP JP2021540709A patent/JP7744828B2/ja active Active
- 2020-08-11 TW TW109127152A patent/TW202120483A/zh unknown
-
2025
- 2025-05-22 JP JP2025085833A patent/JP2025116040A/ja active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004532820A (ja) * | 2001-02-28 | 2004-10-28 | ダウ グローバル テクノロジーズ インコーポレイティド | 標的放射線療法のためのアクチニウム−２２５錯体および複合体 |
| JP2007535492A (ja) * | 2003-12-01 | 2007-12-06 | イムノメディクス， インコーポレイテッド | タンパク質とキレート剤とのコンジュゲートを調製するための改良された方法 |
| JP2017503763A (ja) * | 2013-12-03 | 2017-02-02 | ミレニアム ファーマシューティカルズ， インコーポレイテッドＭｉｌｌｅｎｎｉｕｍ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． | Ｇｃｃ発現細胞を撮像するための化合物及び組成物 |
| WO2018187631A1 (en) * | 2017-04-05 | 2018-10-11 | Cornell University | Trifunctional constructs with tunable pharmacokinetics useful in imaging and anti-tumor therapies |
| WO2021019983A1 (ja) * | 2019-07-30 | 2021-02-04 | Ｊｆｅエンジニアリング株式会社 | ジルコニウム錯体の合成方法 |
Non-Patent Citations (3)
| Title |
|---|
| GHAI, ANCHAL ET AL.: "Optimizing the radiosynthesis of [68Ga] DOTA-MLN6907 peptide containing three disulfide cyclization", APPLIED RADIATION AND ISOTOPES, vol. 140, JPN6020033158, 2018, pages 333 - 341, ISSN: 0005395183 * |
| HASEGAWA, KOKI ET AL.: "Improved 68Ga-labeling method using ethanol addition: Application to the α-helical peptide DOTA-FAM", J LABEL COMPD RADIOPHARM, vol. 60, JPN6020033157, 2017, pages 55 - 61, ISSN: 0005395182 * |
| PEREZ-MALO, MARYLAINE ET AL.: "Improved Efficacy of Synthesizing *MIII-Labeled DOTA Complexes in Binary Mixtures of Water and Organ", INORGANIC CHEMISTRY, vol. 57, JPN6020033156, 2018, pages 6107 - 6117, ISSN: 0005534321 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP4019502A1 (en) | 2022-06-29 |
| JP7744828B2 (ja) | 2025-09-26 |
| US20220259160A1 (en) | 2022-08-18 |
| CA3148288A1 (en) | 2021-02-25 |
| EP4019502A4 (en) | 2023-08-16 |
| CN114269724A (zh) | 2022-04-01 |
| TW202120483A (zh) | 2021-06-01 |
| JP2025116040A (ja) | 2025-08-07 |
| AU2020332618A1 (en) | 2022-02-24 |
| WO2021033530A1 (ja) | 2021-02-25 |
| KR20220047974A (ko) | 2022-04-19 |
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