JPWO2021030533A5 - - Google Patents
Download PDFInfo
- Publication number
- JPWO2021030533A5 JPWO2021030533A5 JP2022509126A JP2022509126A JPWO2021030533A5 JP WO2021030533 A5 JPWO2021030533 A5 JP WO2021030533A5 JP 2022509126 A JP2022509126 A JP 2022509126A JP 2022509126 A JP2022509126 A JP 2022509126A JP WO2021030533 A5 JPWO2021030533 A5 JP WO2021030533A5
- Authority
- JP
- Japan
- Prior art keywords
- rna
- composition
- salt
- denatured
- resin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962886840P | 2019-08-14 | 2019-08-14 | |
| US62/886,840 | 2019-08-14 | ||
| PCT/US2020/046069 WO2021030533A1 (en) | 2019-08-14 | 2020-08-13 | Processes for purifying downstream products of in vitro transcription |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022544416A JP2022544416A (ja) | 2022-10-18 |
| JPWO2021030533A5 true JPWO2021030533A5 (de) | 2023-08-21 |
Family
ID=74571243
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022509126A Pending JP2022544416A (ja) | 2019-08-14 | 2020-08-13 | ｉｎ ｖｉｔｒｏ転写の下流生成物を精製するプロセス |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20220348900A1 (de) |
| EP (1) | EP4013865A4 (de) |
| JP (1) | JP2022544416A (de) |
| CN (1) | CN114269918A (de) |
| AU (1) | AU2020329226A1 (de) |
| BR (1) | BR112022002548A2 (de) |
| CA (1) | CA3149498A1 (de) |
| WO (1) | WO2021030533A1 (de) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11364292B2 (en) | 2015-07-21 | 2022-06-21 | Modernatx, Inc. | CHIKV RNA vaccines |
| WO2017031232A1 (en) | 2015-08-17 | 2017-02-23 | Modernatx, Inc. | Methods for preparing particles and related compositions |
| EP3364950A4 (de) | 2015-10-22 | 2019-10-23 | ModernaTX, Inc. | Impfstoffe gegen tropenkrankheiten |
| SI3718565T1 (sl) | 2015-10-22 | 2022-08-31 | Modernatx, Inc. | Cepiva za respiratorni virus |
| AU2016342045A1 (en) | 2015-10-22 | 2018-06-07 | Modernatx, Inc. | Human cytomegalovirus vaccine |
| EA201891001A1 (ru) | 2015-10-22 | 2018-11-30 | МОДЕРНАТиЭкс, ИНК. | Вакцины на основе нуклеиновых кислот против вируса ветряной оспы (vzv) |
| WO2017099823A1 (en) | 2015-12-10 | 2017-06-15 | Modernatx, Inc. | Compositions and methods for delivery of therapeutic agents |
| MX2019002904A (es) | 2016-09-14 | 2019-09-26 | Modernatx Inc | Composiciones de arn de alta pureza y métodos para su preparación. |
| JP6980780B2 (ja) | 2016-10-21 | 2021-12-15 | モデルナティーエックス， インコーポレイテッド | ヒトサイトメガロウイルスワクチン |
| EP3538146A4 (de) | 2016-11-11 | 2020-07-15 | ModernaTX, Inc. | Influenza-impfstoff |
| US11384352B2 (en) | 2016-12-13 | 2022-07-12 | Modernatx, Inc. | RNA affinity purification |
| MA52262A (fr) | 2017-03-15 | 2020-02-19 | Modernatx Inc | Vaccin à large spectre contre le virus de la grippe |
| US11752206B2 (en) | 2017-03-15 | 2023-09-12 | Modernatx, Inc. | Herpes simplex virus vaccine |
| EP3595713A4 (de) | 2017-03-15 | 2021-01-13 | ModernaTX, Inc. | Impfstoff gegen respiratorisches synzytialvirus |
| WO2018170270A1 (en) | 2017-03-15 | 2018-09-20 | Modernatx, Inc. | Varicella zoster virus (vzv) vaccine |
| US20200030432A1 (en) | 2017-03-17 | 2020-01-30 | Modernatx, Inc. | Zoonotic disease rna vaccines |
| EP3607074A4 (de) | 2017-04-05 | 2021-07-07 | Modernatx, Inc. | Reduktion oder eliminierung von immunantworten auf nicht-intravenös, z. b. subkutan verabreichte therapeutische proteine |
| US11786607B2 (en) | 2017-06-15 | 2023-10-17 | Modernatx, Inc. | RNA formulations |
| US11866696B2 (en) | 2017-08-18 | 2024-01-09 | Modernatx, Inc. | Analytical HPLC methods |
| CN111212905A (zh) | 2017-08-18 | 2020-05-29 | 摩登纳特斯有限公司 | Rna聚合酶变体 |
| WO2019036685A1 (en) | 2017-08-18 | 2019-02-21 | Modernatx, Inc. | METHODS FOR HPLC ANALYSIS |
| WO2019046809A1 (en) | 2017-08-31 | 2019-03-07 | Modernatx, Inc. | METHODS OF MANUFACTURING LIPID NANOPARTICLES |
| MA50253A (fr) | 2017-09-14 | 2020-07-22 | Modernatx Inc | Vaccins à arn contre le virus zika |
| WO2019148101A1 (en) | 2018-01-29 | 2019-08-01 | Modernatx, Inc. | Rsv rna vaccines |
| CN113795579A (zh) | 2019-02-20 | 2021-12-14 | 摩登纳特斯有限公司 | 用于共转录加帽的rna聚合酶变体 |
| US11851694B1 (en) | 2019-02-20 | 2023-12-26 | Modernatx, Inc. | High fidelity in vitro transcription |
| CN113521268A (zh) | 2020-04-22 | 2021-10-22 | 生物技术Rna制药有限公司 | 冠状病毒疫苗 |
| US11406703B2 (en) | 2020-08-25 | 2022-08-09 | Modernatx, Inc. | Human cytomegalovirus vaccine |
| WO2022162027A2 (en) | 2021-01-27 | 2022-08-04 | Curevac Ag | Method of reducing the immunostimulatory properties of in vitro transcribed rna |
| WO2022266389A1 (en) * | 2021-06-17 | 2022-12-22 | Modernatx, Inc. | Alternative rna purification strategies |
| US11878055B1 (en) | 2022-06-26 | 2024-01-23 | BioNTech SE | Coronavirus vaccine |
| WO2024026005A1 (en) * | 2022-07-28 | 2024-02-01 | Modernatx, Inc. | Methods of rna purification |
| CN117603958A (zh) * | 2023-11-23 | 2024-02-27 | 江苏耀海生物制药有限公司 | 一种纯化体外转录mRNA的方法及应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU655766A (en) * | 1967-06-06 | 1968-12-12 | William Wake David | Bulk handling bin |
| AU627764B2 (en) * | 1988-07-08 | 1992-09-03 | Cetus Corp | Gap gene sequences and diagnostic uses thereof |
| US5763573A (en) * | 1988-08-10 | 1998-06-09 | Chiron Corporation | GTPase activating protein fragments |
| CA2065017A1 (en) * | 1989-08-21 | 1991-02-22 | Cetus Oncology Corporation | Peptides from gtpase-activating protein (gap) and diagnostic and therapeutic use thereof |
| WO1993008215A1 (en) * | 1991-10-16 | 1993-04-29 | Cetus Oncology Corporation | Secreted mac-2-binding glycoprotein |
| WO2014152031A1 (en) * | 2013-03-15 | 2014-09-25 | Moderna Therapeutics, Inc. | Ribonucleic acid purification |
-
2020
- 2020-08-13 BR BR112022002548A patent/BR112022002548A2/pt unknown
- 2020-08-13 CA CA3149498A patent/CA3149498A1/en active Pending
- 2020-08-13 US US17/634,939 patent/US20220348900A1/en active Pending
- 2020-08-13 JP JP2022509126A patent/JP2022544416A/ja active Pending
- 2020-08-13 WO PCT/US2020/046069 patent/WO2021030533A1/en unknown
- 2020-08-13 AU AU2020329226A patent/AU2020329226A1/en active Pending
- 2020-08-13 EP EP20853366.1A patent/EP4013865A4/de active Pending
- 2020-08-13 CN CN202080059135.9A patent/CN114269918A/zh active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPWO2021030533A5 (de) | ||
| US20220348900A1 (en) | Processes for purifying downstream products of in vitro transcription | |
| US8084032B2 (en) | Purification method which prevents denaturation of an antibody | |
| WO2017184984A1 (en) | Biomolecule processing from fixed biological samples | |
| JP2010504738A5 (de) | ||
| JP6788533B2 (ja) | 陰イオン交換クロマトグラフィによるタンパク質の精製方法 | |
| TW202321446A (zh) | 多管柱層析ｍＲＮＡ純化 | |
| CA2340863A1 (en) | Thrombin preparations and process for their production | |
| GB2443505B (en) | Nucleic acid purification method | |
| EP0416983A1 (de) | Verfahren zur Herstellung eines Konzentrats des Faktor VIII-von Willebrand-Faktor-Komplexes der Blutgerinnung aus Vollplasma | |
| US20140128577A1 (en) | Purification of chimeric protein | |
| JP2012510500A5 (de) | ||
| JP2013194054A5 (de) | ||
| JP2007523883A5 (de) | ||
| CA2531969C (en) | Protein-refolding material | |
| KR100320394B1 (ko) | 멤브레인크로마토그래피시켜비타민-k의존형단백질을정제시키는방법 | |
| Ramseyer et al. | Purification of the cAMP receptor protein by affinity chromatography | |
| RU2014108241A (ru) | Способ катион- и анионобменной хроматографии | |
| RU2022106276A (ru) | Способы очистки последующих продуктов транскрипции in vitro | |
| JP4865569B2 (ja) | 細菌で発現したタンパク質の精製方法 | |
| JP3251545B2 (ja) | 精子運動能促進性高分子タンパク質 | |
| EP3896159A1 (de) | Verfahren zur einzelstrang-rna-reinigung unter verwendung eines anionenaustauschers | |
| CN107903301A (zh) | 一种糖基化蛋白的分离方法 | |
| JPWO2021209595A5 (de) | ||
| Shkil et al. | Mild and efficient catalyst for nitrodopamine synthesis: from milligram to multi-gram scales |