JPWO2021022186A5 - - Google Patents
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- Publication number
- JPWO2021022186A5 JPWO2021022186A5 JP2022506384A JP2022506384A JPWO2021022186A5 JP WO2021022186 A5 JPWO2021022186 A5 JP WO2021022186A5 JP 2022506384 A JP2022506384 A JP 2022506384A JP 2022506384 A JP2022506384 A JP 2022506384A JP WO2021022186 A5 JPWO2021022186 A5 JP WO2021022186A5
- Authority
- JP
- Japan
- Prior art keywords
- disease
- cancer
- syndrome
- autoimmune
- pruritus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962881026P | 2019-07-31 | 2019-07-31 | |
| US62/881,026 | 2019-07-31 | ||
| PCT/US2020/044558 WO2021022186A1 (en) | 2019-07-31 | 2020-07-31 | Deuterated mk2 pathway inhibitors and methods of using the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022542434A JP2022542434A (ja) | 2022-10-03 |
| JPWO2021022186A5 true JPWO2021022186A5 (ko) | 2023-07-19 |
Family
ID=74228512
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022506384A Pending JP2022542434A (ja) | 2019-07-31 | 2020-07-31 | 重水素化ｍｋ２経路阻害剤およびその使用方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20220288070A1 (ko) |
| EP (1) | EP4003344A4 (ko) |
| JP (1) | JP2022542434A (ko) |
| KR (1) | KR20220041180A (ko) |
| CN (1) | CN114206339A (ko) |
| AU (1) | AU2020319879A1 (ko) |
| BR (1) | BR112022001324A2 (ko) |
| CA (1) | CA3149304A1 (ko) |
| IL (1) | IL290045A (ko) |
| MX (1) | MX2022001151A (ko) |
| WO (1) | WO2021022186A1 (ko) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3172088A1 (en) * | 2020-03-27 | 2021-09-30 | Walter Smith | Oral compositions of mk2 pathway inhibitor for treatment of immune conditions |
| CR20230468A (es) | 2021-03-31 | 2023-12-07 | Xinthera Inc | Inhibidores de mk2 y usos de estos |
| TW202317544A (zh) | 2021-07-09 | 2023-05-01 | 美商辛瑟拉股份有限公司 | 吡啶酮mk2抑制劑及其用途 |
| WO2023001282A1 (zh) * | 2021-07-23 | 2023-01-26 | 南京明德新药研发有限公司 | 杂环取代的嘧啶衍生物 |
| WO2023125707A1 (zh) * | 2021-12-29 | 2023-07-06 | 上海美悦生物科技发展有限公司 | 一种p38 MAPK/MK2通路调节剂及其组合物、制备方法和用途 |
| WO2023134765A1 (zh) * | 2022-01-14 | 2023-07-20 | 上海翰森生物医药科技有限公司 | 含五元环类衍生物、其制备方法和应用 |
| CN118525005A (zh) | 2022-01-14 | 2024-08-20 | 上海翰森生物医药科技有限公司 | 含吡啶多环类衍生物、其制备方法和应用 |
| US20230286950A1 (en) * | 2022-02-04 | 2023-09-14 | Aclaris Therapeutics, Inc. | Methods of synthesizing deuterated substituted pyridinone-pyridinyl compounds |
| WO2023165554A1 (zh) * | 2022-03-03 | 2023-09-07 | 深圳信立泰药业股份有限公司 | 一种氘代三联吡啶二酮化合物或其盐及其制备方法与应用 |
| WO2024150014A1 (en) | 2023-01-13 | 2024-07-18 | Poolbeg Pharma (UK) Limited | Medicinal products and methods for the alleviation of cancer immunotherapy-associated cytokine release syndrome |
| CN118344289A (zh) * | 2023-01-13 | 2024-07-16 | 上海美悦生物科技发展有限公司 | 苯基取代的杂芳基类化合物及其药物组合物、制备方法和用途 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010136474A2 (en) * | 2009-05-28 | 2010-12-02 | Novartis Ag | Substituted aminobutyric derivatives as neprilysin inhibitors |
| JP5848775B2 (ja) * | 2010-12-06 | 2016-01-27 | コンフルエンス・ライフ・サイエンシズ，インコーポレーテッド | 置換ピリジノンピリジニル化合物 |
| US9359300B2 (en) * | 2010-12-06 | 2016-06-07 | Confluence Life Sciences, Inc. | Methyl/difluorophenyl-methoxy substituted pyridinone-pyridinyl compounds, methyl-pyridinyl-methoxy substituted pyridinone-pyridinyl compounds, and methyl-pyrimidinyl-methoxy substituted pyridinone-pyridinyl compounds |
| LT3003039T (lt) * | 2013-06-07 | 2021-05-10 | Aclaris Therapeutics, Inc. | Metil/fluor-piridinil-metoksi grupės pakeistieji piridinono-piridinilo junginiai ir fluor-pirimidinil-metoksi grupės pakeistieji piridinono-piridinilo junginiai |
| WO2017180589A1 (en) * | 2016-04-11 | 2017-10-19 | Auspex Pharmaceuticals, Inc. | Deuterated ketamine derivatives |
| TWI828644B (zh) * | 2017-12-06 | 2024-01-11 | 仁新醫藥股份有限公司 | 微管蛋白抑制劑 |
-
2020
- 2020-07-31 JP JP2022506384A patent/JP2022542434A/ja active Pending
- 2020-07-31 AU AU2020319879A patent/AU2020319879A1/en not_active Abandoned
- 2020-07-31 EP EP20847487.4A patent/EP4003344A4/en active Pending
- 2020-07-31 BR BR112022001324A patent/BR112022001324A2/pt unknown
- 2020-07-31 WO PCT/US2020/044558 patent/WO2021022186A1/en unknown
- 2020-07-31 US US17/630,414 patent/US20220288070A1/en active Pending
- 2020-07-31 CA CA3149304A patent/CA3149304A1/en active Pending
- 2020-07-31 KR KR1020227006713A patent/KR20220041180A/ko unknown
- 2020-07-31 MX MX2022001151A patent/MX2022001151A/es unknown
- 2020-07-31 CN CN202080051376.9A patent/CN114206339A/zh active Pending
-
2022
- 2022-01-23 IL IL290045A patent/IL290045A/en unknown
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