JPWO2021010301A5 - - Google Patents
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- Publication number
- JPWO2021010301A5 JPWO2021010301A5 JP2021533025A JP2021533025A JPWO2021010301A5 JP WO2021010301 A5 JPWO2021010301 A5 JP WO2021010301A5 JP 2021533025 A JP2021533025 A JP 2021533025A JP 2021533025 A JP2021533025 A JP 2021533025A JP WO2021010301 A5 JPWO2021010301 A5 JP WO2021010301A5
- Authority
- JP
- Japan
- Prior art keywords
- dux4
- oligonucleotide
- pharmaceutically acceptable
- acceptable salt
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019129735 | 2019-07-12 | ||
| JP2019129735 | 2019-07-12 | ||
| PCT/JP2020/026950 WO2021010301A1 (ja) | 2019-07-12 | 2020-07-10 | ＤＵＸ４ ｐｒｅ－ｍＲＮＡのスプライシングを変化させるアンチセンスオリゴヌクレオチド |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPWO2021010301A1 JPWO2021010301A1 (https=) | 2021-01-21 |
| JPWO2021010301A5 true JPWO2021010301A5 (https=) | 2023-07-25 |
| JP7627495B2 JP7627495B2 (ja) | 2025-02-06 |
Family
ID=74210830
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021533025A Active JP7627495B2 (ja) | 2019-07-12 | 2020-07-10 | ＤＵＸ４ ｐｒｅ－ｍＲＮＡのスプライシングを変化させるアンチセンスオリゴヌクレオチド |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20220364086A1 (https=) |
| EP (1) | EP3998108A4 (https=) |
| JP (1) | JP7627495B2 (https=) |
| KR (1) | KR20220032004A (https=) |
| CN (1) | CN114026234A (https=) |
| AU (1) | AU2020313255A1 (https=) |
| BR (1) | BR112021024764A2 (https=) |
| CA (1) | CA3142925A1 (https=) |
| IL (1) | IL288596A (https=) |
| TW (1) | TW202117015A (https=) |
| WO (1) | WO2021010301A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20230023612A (ko) | 2020-04-02 | 2023-02-17 | 마이레큘, 인크. | 조작된 올리고뉴클레오티드를 사용한 표적화된 억제 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0787982A (ja) | 1993-01-29 | 1995-04-04 | Sankyo Co Ltd | 修飾オリゴデオキシリボヌクレオチド |
| US6096881A (en) | 1997-05-30 | 2000-08-01 | Hybridon, Inc. | Sulfur transfer reagents for oligonucleotide synthesis |
| JP4236812B2 (ja) | 1997-09-12 | 2009-03-11 | エクシコン エ／エス | オリゴヌクレオチド類似体 |
| ES2234563T5 (es) | 1999-02-12 | 2018-01-17 | Daiichi Sankyo Company, Limited | Nuevos análogos de nucleósidos y oligonucleótidos |
| US6261840B1 (en) | 2000-01-18 | 2001-07-17 | Isis Pharmaceuticals, Inc. | Antisense modulation of PTP1B expression |
| ES2596977T3 (es) * | 2010-09-02 | 2017-01-13 | Université de Mons | Agentes útiles en el tratamiento de la distrofia muscular facioescapulohumeral |
| EP2736539B1 (en) * | 2011-07-25 | 2017-08-23 | Nationwide Children's Hospital, Inc. | Recombinant virus products and methods for inhibition of expression of dux4 |
| WO2013120038A2 (en) * | 2012-02-10 | 2013-08-15 | Regents Of The University Of Minnesota | Morpholino targeting dux4 for treating fshd |
| WO2014109384A1 (ja) | 2013-01-10 | 2014-07-17 | 塩野義製薬株式会社 | 架橋型核酸誘導体の製造方法 |
| US20180237775A1 (en) * | 2015-09-21 | 2018-08-23 | Association Institut De Myologie | Antisense oligonucleotides and uses thereof |
| JP6966463B2 (ja) * | 2016-02-26 | 2021-11-17 | リサーチ インスティチュート アット ネイションワイド チルドレンズ ホスピタル | 組換えウイルス産物及びｄｕｘ４エクソンスキッピングを誘導するための方法 |
| CN109462995A (zh) | 2016-05-04 | 2019-03-12 | 波涛生命科学有限公司 | 生物活性剂的方法和组合物 |
| WO2019060432A2 (en) * | 2017-09-19 | 2019-03-28 | Children's National Medical Center | GAPMERS AND METHODS OF USING THE SAME FOR THE TREATMENT OF MUSCLE DYSTROPHY |
| JP2019129735A (ja) | 2018-01-30 | 2019-08-08 | 株式会社ＧＩＳｕｐｐｌｙ | 有害動物の捕獲支援システム |
-
2020
- 2020-07-10 US US17/621,449 patent/US20220364086A1/en not_active Abandoned
- 2020-07-10 JP JP2021533025A patent/JP7627495B2/ja active Active
- 2020-07-10 BR BR112021024764A patent/BR112021024764A2/pt not_active Application Discontinuation
- 2020-07-10 KR KR1020217040852A patent/KR20220032004A/ko not_active Withdrawn
- 2020-07-10 AU AU2020313255A patent/AU2020313255A1/en not_active Abandoned
- 2020-07-10 WO PCT/JP2020/026950 patent/WO2021010301A1/ja not_active Ceased
- 2020-07-10 CN CN202080045492.XA patent/CN114026234A/zh active Pending
- 2020-07-10 TW TW109123473A patent/TW202117015A/zh unknown
- 2020-07-10 CA CA3142925A patent/CA3142925A1/en active Pending
- 2020-07-10 EP EP20841146.2A patent/EP3998108A4/en not_active Withdrawn
-
2021
- 2021-12-01 IL IL288596A patent/IL288596A/en unknown
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