JPWO2020264512A5 - - Google Patents
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- Publication number
- JPWO2020264512A5 JPWO2020264512A5 JP2021577427A JP2021577427A JPWO2020264512A5 JP WO2020264512 A5 JPWO2020264512 A5 JP WO2020264512A5 JP 2021577427 A JP2021577427 A JP 2021577427A JP 2021577427 A JP2021577427 A JP 2021577427A JP WO2020264512 A5 JPWO2020264512 A5 JP WO2020264512A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- unsubstituted
- compound
- pharmaceutically acceptable
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025017657A JP2025065311A (ja) | 2019-06-27 | 2025-02-05 | Ｃｎｓ障害を治療するための組成物及び方法 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962867695P | 2019-06-27 | 2019-06-27 | |
| US201962867736P | 2019-06-27 | 2019-06-27 | |
| US201962867734P | 2019-06-27 | 2019-06-27 | |
| US62/867,695 | 2019-06-27 | ||
| US62/867,734 | 2019-06-27 | ||
| US62/867,736 | 2019-06-27 | ||
| PCT/US2020/040164 WO2020264512A1 (en) | 2019-06-27 | 2020-06-29 | Compounds for treating cns disorders |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025017657A Division JP2025065311A (ja) | 2019-06-27 | 2025-02-05 | Ｃｎｓ障害を治療するための組成物及び方法 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2022538301A JP2022538301A (ja) | 2022-09-01 |
| JP2022538301A5 JP2022538301A5 (https=) | 2023-07-11 |
| JPWO2020264512A5 true JPWO2020264512A5 (https=) | 2023-07-11 |
| JP7670632B2 JP7670632B2 (ja) | 2025-04-30 |
Family
ID=71728948
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021577427A Active JP7670632B2 (ja) | 2019-06-27 | 2020-06-29 | Ｃｎｓ障害を治療するための組成物及び方法 |
| JP2025017657A Pending JP2025065311A (ja) | 2019-06-27 | 2025-02-05 | Ｃｎｓ障害を治療するための組成物及び方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025017657A Pending JP2025065311A (ja) | 2019-06-27 | 2025-02-05 | Ｃｎｓ障害を治療するための組成物及び方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20230257415A1 (https=) |
| EP (1) | EP3990468A1 (https=) |
| JP (2) | JP7670632B2 (https=) |
| CN (1) | CN114729000A (https=) |
| AU (1) | AU2020304679A1 (https=) |
| BR (1) | BR112021026445A2 (https=) |
| CA (1) | CA3143545A1 (https=) |
| MX (1) | MX2021015854A (https=) |
| TW (1) | TWI896548B (https=) |
| WO (1) | WO2020264512A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2015002252A (es) | 2012-08-21 | 2015-07-21 | Sage Therapeutics Inc | Metodos para tratar epilepsia o estado de epilepsia. |
| JP6470258B2 (ja) | 2013-04-17 | 2019-02-13 | セージ セラピューティクス， インコーポレイテッド | １９−ノルｃ３，３−ジ置換ｃ２１−ｎ−ピラゾリルステロイドおよびその使用方法 |
| WO2015195962A1 (en) | 2014-06-18 | 2015-12-23 | Sage Therapeutics, Inc. | Neuroactive steroids, compositions, and uses thereof |
| JOP20200195A1 (ar) | 2014-09-08 | 2017-06-16 | Sage Therapeutics Inc | سترويدات وتركيبات نشطة عصبياً، واستخداماتها |
| WO2016082789A1 (en) | 2014-11-27 | 2016-06-02 | Sage Therapeutics, Inc. | Compositions and methods for treating cns disorders |
| TWI904593B (zh) | 2016-08-23 | 2025-11-11 | 美商賽吉醫療公司 | 結晶19-去甲c3,3-二取代之c21-n-吡唑類固醇 |
| EP3720867A1 (en) | 2017-12-08 | 2020-10-14 | Sage Therapeutics, Inc. | Deuterated 21 -[4-cyano-pyrazol-1 -yl]-19-nor-pregan-3. alpha-ol-20-one derivatives for treating cns disorders |
| CN113166193B (zh) | 2018-10-12 | 2025-08-19 | 萨奇治疗股份有限公司 | 用于治疗cns病症的在位置10处被环状基团取代的神经活性类固醇 |
| IL283629B2 (en) | 2018-12-05 | 2026-03-01 | Sage Therapeutics Inc | Neuroactive steroids and methods of using them |
| CN116589521B (zh) * | 2019-01-08 | 2025-07-11 | 成都康弘药业集团股份有限公司 | 甾体类化合物、用途及其制备方法 |
| CR20240234A (es) | 2019-05-31 | 2024-07-09 | Sage Therapeutics Inc | ESTEROIDES NEUROACTIVOS Y COMPOSICIONES DE ESTOS (Divisional 2021-629) |
| JP7787635B2 (ja) | 2019-06-27 | 2025-12-17 | セージ セラピューティクス， エルエルシー | Ｃｎｓ障害を治療するための組成物及び方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2969M (fr) * | 1963-05-22 | 1964-11-30 | Roussel Uclaf | Nouveau médicament notamment pour le traitement des spasmes d'origine coronarienne on viscérale. |
| ES432106A1 (es) * | 1973-11-30 | 1976-11-01 | Schering Ag | Procedimiento para la preparacion de d-homo-20-cetopregna- nos. |
| IL48628A0 (en) * | 1974-12-23 | 1976-02-29 | Schering Ag | D-homo-20-keto-pregnanes and process for their manufactur |
| GB1570394A (en) * | 1976-01-06 | 1980-07-02 | Glaxo Lab Ltd | 11-acyloxy-3-hydroxy steroids |
| GB1581234A (en) * | 1976-04-05 | 1980-12-10 | Glaxo Operations Ltd | 11a - amino - 3a - hydroxysteroids |
| GB1581235A (en) * | 1977-04-04 | 1980-12-10 | Glaxo Operations Ltd | 11a-amino-3a-hydroxy-steroids |
| US5376645A (en) | 1990-01-23 | 1994-12-27 | University Of Kansas | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
| FI972202L (fi) * | 1994-11-23 | 1997-07-17 | Cocensys Inc | Androstaanit ja pregnaanit GABA-reseptoreiden allosteeriseen muunteluun |
| AU3967297A (en) * | 1996-08-01 | 1998-02-25 | Cocensys, Inc. | Use of gaba and nmda receptor ligands for the treatment of migraine headache |
| JP6470258B2 (ja) | 2013-04-17 | 2019-02-13 | セージ セラピューティクス， インコーポレイテッド | １９−ノルｃ３，３−ジ置換ｃ２１−ｎ−ピラゾリルステロイドおよびその使用方法 |
| EP4155314A1 (en) | 2015-02-20 | 2023-03-29 | Sage Therapeutics, Inc. | Neuroactive steroids, compositions, and uses thereof |
| MA45599A (fr) | 2016-07-11 | 2019-05-15 | Sage Therapeutics Inc | Stéroïdes neuroactifs substitués en c17, c20 et c21 et leurs procédés d'utilisation |
| CN111741965B (zh) | 2017-12-22 | 2024-06-25 | 萨奇治疗股份有限公司 | 治疗中枢神经系统疾病的组合物和方法 |
| CN114656514B (zh) * | 2018-02-11 | 2024-05-14 | 江苏豪森药业集团有限公司 | 一种甾族类衍生物调节剂及其制备方法和应用 |
| IL283629B2 (en) * | 2018-12-05 | 2026-03-01 | Sage Therapeutics Inc | Neuroactive steroids and methods of using them |
-
2020
- 2020-06-29 US US17/620,275 patent/US20230257415A1/en not_active Abandoned
- 2020-06-29 MX MX2021015854A patent/MX2021015854A/es unknown
- 2020-06-29 WO PCT/US2020/040164 patent/WO2020264512A1/en not_active Ceased
- 2020-06-29 EP EP20743477.0A patent/EP3990468A1/en active Pending
- 2020-06-29 JP JP2021577427A patent/JP7670632B2/ja active Active
- 2020-06-29 TW TW109121959A patent/TWI896548B/zh active
- 2020-06-29 CN CN202080059462.4A patent/CN114729000A/zh active Pending
- 2020-06-29 BR BR112021026445A patent/BR112021026445A2/pt unknown
- 2020-06-29 AU AU2020304679A patent/AU2020304679A1/en active Pending
- 2020-06-29 CA CA3143545A patent/CA3143545A1/en active Pending
-
2023
- 2023-09-25 US US18/473,702 patent/US20240300996A1/en active Pending
-
2025
- 2025-02-05 JP JP2025017657A patent/JP2025065311A/ja active Pending
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