JPWO2021188778A5 - - Google Patents
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- Publication number
- JPWO2021188778A5 JPWO2021188778A5 JP2022556035A JP2022556035A JPWO2021188778A5 JP WO2021188778 A5 JPWO2021188778 A5 JP WO2021188778A5 JP 2022556035 A JP2022556035 A JP 2022556035A JP 2022556035 A JP2022556035 A JP 2022556035A JP WO2021188778 A5 JPWO2021188778 A5 JP WO2021188778A5
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- JP
- Japan
- Prior art keywords
- unsubstituted
- substituted
- group
- acceptable salt
- compound according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025188453A JP2026021531A (ja) | 2020-03-18 | 2025-11-07 | 神経刺激性ステロイド及びその使用方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062991234P | 2020-03-18 | 2020-03-18 | |
| US62/991,234 | 2020-03-18 | ||
| PCT/US2021/022933 WO2021188778A2 (en) | 2020-03-18 | 2021-03-18 | Neuroactive steroids and their methods of use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025188453A Division JP2026021531A (ja) | 2020-03-18 | 2025-11-07 | 神経刺激性ステロイド及びその使用方法 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2023518411A JP2023518411A (ja) | 2023-05-01 |
| JPWO2021188778A5 true JPWO2021188778A5 (https=) | 2024-03-29 |
| JP2023518411A5 JP2023518411A5 (https=) | 2024-03-29 |
| JP7817179B2 JP7817179B2 (ja) | 2026-02-18 |
Family
ID=75478218
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022556035A Active JP7817179B2 (ja) | 2020-03-18 | 2021-03-18 | 神経刺激性ステロイド及びその使用方法 |
| JP2025188453A Pending JP2026021531A (ja) | 2020-03-18 | 2025-11-07 | 神経刺激性ステロイド及びその使用方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025188453A Pending JP2026021531A (ja) | 2020-03-18 | 2025-11-07 | 神経刺激性ステロイド及びその使用方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20240239835A9 (https=) |
| EP (1) | EP4121438A2 (https=) |
| JP (2) | JP7817179B2 (https=) |
| CN (1) | CN115551874A (https=) |
| AR (1) | AR121609A1 (https=) |
| AU (1) | AU2021238346A1 (https=) |
| CA (1) | CA3175324A1 (https=) |
| IL (1) | IL296371A (https=) |
| TW (1) | TW202143976A (https=) |
| WO (1) | WO2021188778A2 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG10201606063RA (en) | 2012-01-23 | 2016-09-29 | Sage Therapeutics Inc | Neuroactive steroid formulations and methods of treating cns disorders |
| MX2015002252A (es) | 2012-08-21 | 2015-07-21 | Sage Therapeutics Inc | Metodos para tratar epilepsia o estado de epilepsia. |
| JP6470258B2 (ja) | 2013-04-17 | 2019-02-13 | セージ セラピューティクス， インコーポレイテッド | １９−ノルｃ３，３−ジ置換ｃ２１−ｎ−ピラゾリルステロイドおよびその使用方法 |
| WO2015195962A1 (en) | 2014-06-18 | 2015-12-23 | Sage Therapeutics, Inc. | Neuroactive steroids, compositions, and uses thereof |
| JOP20200195A1 (ar) | 2014-09-08 | 2017-06-16 | Sage Therapeutics Inc | سترويدات وتركيبات نشطة عصبياً، واستخداماتها |
| WO2016082789A1 (en) | 2014-11-27 | 2016-06-02 | Sage Therapeutics, Inc. | Compositions and methods for treating cns disorders |
| TWI904593B (zh) | 2016-08-23 | 2025-11-11 | 美商賽吉醫療公司 | 結晶19-去甲c3,3-二取代之c21-n-吡唑類固醇 |
| EP3720867A1 (en) | 2017-12-08 | 2020-10-14 | Sage Therapeutics, Inc. | Deuterated 21 -[4-cyano-pyrazol-1 -yl]-19-nor-pregan-3. alpha-ol-20-one derivatives for treating cns disorders |
| MA51568A (fr) | 2018-01-12 | 2021-04-21 | Sage Therapeutics Inc | Composés aza-, oxa et thia-pregnan-20-one-3.alpha.-ol s'utilisant dans le traitement de troubles du système nerveux central |
| CN113166193B (zh) | 2018-10-12 | 2025-08-19 | 萨奇治疗股份有限公司 | 用于治疗cns病症的在位置10处被环状基团取代的神经活性类固醇 |
| KR20250124139A (ko) * | 2022-11-21 | 2025-08-19 | 세이지 테라퓨틱스, 인크. | 음성 nmda-조정 화합물 및 이의 사용 방법 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5376645A (en) | 1990-01-23 | 1994-12-27 | University Of Kansas | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
| AU698834B2 (en) * | 1993-05-24 | 1998-11-12 | Purdue Pharma Ltd. | Methods and compositions for inducing sleep |
| FI972202L (fi) * | 1994-11-23 | 1997-07-17 | Cocensys Inc | Androstaanit ja pregnaanit GABA-reseptoreiden allosteeriseen muunteluun |
| RU2194712C2 (ru) * | 1995-06-06 | 2002-12-20 | Коукенсис, Инк. | НЕЙРОАКТИВНЫЕ СТЕРОИДЫ, ФАРМАЦЕВТИЧЕСКИЙ ПРЕПАРАТ, СПОСОБ ЛЕЧЕНИЯ ИЛИ ПРОФИЛАКТИКИ РАЗЛИЧНЫХ НАРУШЕНИЙ, СПОСОБ ИНДУКЦИИ СНА И СПОСОБ ИНДУКЦИИ АНЕСТЕЗИИ С ИХ ИСПОЛЬЗОВАНИЕМ, СПОСОБ МОДУЛИРОВАНИЯ КОМПЛЕКСА РЕЦЕПТОР ГАМКa-ХЛОРИДНЫЙ ИОНОФОР |
| AU3967297A (en) * | 1996-08-01 | 1998-02-25 | Cocensys, Inc. | Use of gaba and nmda receptor ligands for the treatment of migraine headache |
| HRP20230747T1 (hr) * | 2011-09-08 | 2024-01-05 | Sage Therapeutics, Inc. | Neuroaktivni steroidi, pripravci i njihova uporaba |
| ME03809B (me) * | 2014-10-16 | 2021-04-20 | Sage Therapeutics Inc | KOMPOZICIJE I POSTUPCI ZA LEČENJE POREMEĆAJA CNS-a |
| CN109503694A (zh) * | 2018-11-21 | 2019-03-22 | 苏州闻天医药科技有限公司 | 一种新型gabaa受体调节剂及其用途 |
| IL283629B2 (en) | 2018-12-05 | 2026-03-01 | Sage Therapeutics Inc | Neuroactive steroids and methods of using them |
| WO2020135454A1 (zh) * | 2018-12-26 | 2020-07-02 | 张家口华健致远生物科技有限公司 | 一类类固醇化合物及其用途 |
| CR20240234A (es) | 2019-05-31 | 2024-07-09 | Sage Therapeutics Inc | ESTEROIDES NEUROACTIVOS Y COMPOSICIONES DE ESTOS (Divisional 2021-629) |
| CN112391512B (zh) * | 2019-08-13 | 2022-03-18 | 宝山钢铁股份有限公司 | 一种高磁感取向硅钢及其制造方法 |
| WO2021142477A1 (en) | 2020-01-12 | 2021-07-15 | Brii Biosciences, Inc. | Neuroactive steroids and pharmaceutical composition containing the same |
| JP2024074633A (ja) * | 2022-11-21 | 2024-05-31 | 小松ウオール工業株式会社 | 間仕切り装置と、間仕切り装置における横桟の支持構造 |
-
2021
- 2021-03-18 TW TW110109815A patent/TW202143976A/zh unknown
- 2021-03-18 AR ARP210100680A patent/AR121609A1/es unknown
- 2021-03-18 JP JP2022556035A patent/JP7817179B2/ja active Active
- 2021-03-18 CA CA3175324A patent/CA3175324A1/en active Pending
- 2021-03-18 AU AU2021238346A patent/AU2021238346A1/en active Pending
- 2021-03-18 CN CN202180034459.1A patent/CN115551874A/zh active Pending
- 2021-03-18 EP EP21718329.2A patent/EP4121438A2/en active Pending
- 2021-03-18 IL IL296371A patent/IL296371A/en unknown
- 2021-03-18 WO PCT/US2021/022933 patent/WO2021188778A2/en not_active Ceased
- 2021-03-18 US US17/912,301 patent/US20240239835A9/en active Pending
-
2025
- 2025-11-07 JP JP2025188453A patent/JP2026021531A/ja active Pending