MA51568A - Composés aza-, oxa et thia-pregnan-20-one-3.alpha.-ol s'utilisant dans le traitement de troubles du système nerveux central - Google Patents
Composés aza-, oxa et thia-pregnan-20-one-3.alpha.-ol s'utilisant dans le traitement de troubles du système nerveux centralInfo
- Publication number
- MA51568A MA51568A MA051568A MA51568A MA51568A MA 51568 A MA51568 A MA 51568A MA 051568 A MA051568 A MA 051568A MA 51568 A MA51568 A MA 51568A MA 51568 A MA51568 A MA 51568A
- Authority
- MA
- Morocco
- Prior art keywords
- pregnan
- thia
- aza
- oxa
- alpha
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
- C07J73/001—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
- C07J73/003—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by oxygen as hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
- C07J73/001—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
- C07J73/005—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by nitrogen as hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
- C07J73/001—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
- C07J73/006—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by sulfur as hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
- C07J75/005—Preparation of steroids by cyclization of non-steroid compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862616768P | 2018-01-12 | 2018-01-12 | |
US201862617134P | 2018-01-12 | 2018-01-12 | |
US201862728514P | 2018-09-07 | 2018-09-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA51568A true MA51568A (fr) | 2021-04-21 |
Family
ID=65324563
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA051568A MA51568A (fr) | 2018-01-12 | 2019-01-11 | Composés aza-, oxa et thia-pregnan-20-one-3.alpha.-ol s'utilisant dans le traitement de troubles du système nerveux central |
Country Status (6)
Country | Link |
---|---|
US (2) | US11718642B2 (fr) |
EP (1) | EP3737687A1 (fr) |
JP (2) | JP7538040B2 (fr) |
MA (1) | MA51568A (fr) |
TW (1) | TW201930269A (fr) |
WO (1) | WO2019140272A1 (fr) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RS59734B1 (sr) | 2012-01-23 | 2020-02-28 | Sage Therapeutics Inc | Formulacije neuroaktivnog steroida koje uključuju kompleks alopregnanolona i sulfobutil etar beta-ciklodekstrina |
US20140057885A1 (en) | 2012-08-21 | 2014-02-27 | Sage Therapeutics, Inc. | Methods of treating epilepsy or status epilepticus |
US10246482B2 (en) | 2014-06-18 | 2019-04-02 | Sage Therapeutics, Inc. | Neuroactive steroids, compositions, and uses thereof |
JOP20200195A1 (ar) | 2014-09-08 | 2017-06-16 | Sage Therapeutics Inc | سترويدات وتركيبات نشطة عصبياً، واستخداماتها |
PT3224269T (pt) | 2014-11-27 | 2020-06-01 | Sage Therapeutics Inc | Composições e métodos para tratamento de distúrbios do snc |
CN110088091A (zh) | 2016-08-23 | 2019-08-02 | 萨奇治疗股份有限公司 | 19-去甲c3,3-二取代的c21-n-吡唑基类固醇的晶体 |
KR20200096596A (ko) | 2017-12-08 | 2020-08-12 | 세이지 테라퓨틱스, 인크. | Cns 장애의 치료를 위한 중수소화 21 -[4-시아노-피라졸-1 -일]-19-노르-프레간-3. 알파-올-20-온 유도체 |
US10857163B1 (en) | 2019-09-30 | 2020-12-08 | Athenen Therapeutics, Inc. | Compositions that preferentially potentiate subtypes of GABAA receptors and methods of use thereof |
EP4069250A1 (fr) * | 2019-12-05 | 2022-10-12 | Sage Therapeutics, Inc. | Stéroïde c21-n-pyrazolyl 19-nor c3,3-disubstitué et ses méthodes d'utilisation |
CN111233815B (zh) * | 2020-01-21 | 2022-10-14 | 上海应用技术大学 | 一种异阿根廷蚁素的制备方法 |
US20230346801A1 (en) | 2020-03-25 | 2023-11-02 | Sage Therapeutics, Inc. | Use of agents for treatment of respiratory conditions |
US12116382B2 (en) | 2022-11-28 | 2024-10-15 | Hongene Biotech Corporation | Functionalized N-acetylgalactosamine analogs |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL48628A0 (en) * | 1974-12-23 | 1976-02-29 | Schering Ag | D-homo-20-keto-pregnanes and process for their manufactur |
US5376645A (en) | 1990-01-23 | 1994-12-27 | University Of Kansas | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
EP0701444B1 (fr) | 1993-05-24 | 2010-04-07 | Purdue Pharma Ltd. | Procedes et compositions induisant le sommeil |
DE69519945T2 (de) | 1994-11-23 | 2001-06-07 | Cocensys, Inc. | Androstan- und pregnanserien für die allosterische modulation des gaba-rezeptors |
ES2235187T3 (es) | 1995-06-06 | 2005-07-01 | Euro-Celtique S.A. | Esteroides neuroactivos de las series del androstano y el pregnano. |
WO1998005337A1 (fr) | 1996-08-01 | 1998-02-12 | Cocensys, Inc. | Utilisation de ligands de recepteurs gaba et nmda pour le traitement des cephalees de la migraine |
CN118754924A (zh) * | 2013-04-17 | 2024-10-11 | 萨奇治疗股份有限公司 | 19-去甲c3,3-二取代的c21-n-吡唑基类固醇及其使用方法 |
LT3206493T (lt) | 2014-10-16 | 2020-08-25 | Sage Therapeutics, Inc. | Kompozicijos ir būdai, skirti cns sutrikimams gydyti |
BR112020012761A2 (pt) | 2017-12-22 | 2021-02-17 | Sage Therapeutics, Inc. | composições e métodos para o tratamento de distúrbios do snc |
WO2019154257A1 (fr) | 2018-02-11 | 2019-08-15 | 江苏豪森药业集团有限公司 | Régulateur de dérivé de stéroïde, son procédé de préparation et son utilisation |
CN109503694A (zh) | 2018-11-21 | 2019-03-22 | 苏州闻天医药科技有限公司 | 一种新型gabaa受体调节剂及其用途 |
US20230322846A9 (en) | 2018-12-05 | 2023-10-12 | Sage Therapeutics, Inc. | Neuroactive steroids and their methods of use |
WO2020135454A1 (fr) | 2018-12-26 | 2020-07-02 | 张家口华健致远生物科技有限公司 | Classe de composés stéroïdes et leur utilisation |
IL296371A (en) | 2020-03-18 | 2022-11-01 | Sage Therapeutics Inc | Neuroactive steroids and methods of using them |
-
2019
- 2019-01-11 EP EP19703816.9A patent/EP3737687A1/fr active Pending
- 2019-01-11 MA MA051568A patent/MA51568A/fr unknown
- 2019-01-11 WO PCT/US2019/013315 patent/WO2019140272A1/fr unknown
- 2019-01-11 JP JP2020538573A patent/JP7538040B2/ja active Active
- 2019-01-11 US US16/961,097 patent/US11718642B2/en active Active
- 2019-01-11 TW TW108101261A patent/TW201930269A/zh unknown
-
2023
- 2023-06-05 US US18/328,865 patent/US20240150393A1/en active Pending
- 2023-08-03 JP JP2023127398A patent/JP2023145726A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2023145726A (ja) | 2023-10-11 |
EP3737687A1 (fr) | 2020-11-18 |
US20200354399A1 (en) | 2020-11-12 |
JP7538040B2 (ja) | 2024-08-21 |
JP2021510695A (ja) | 2021-04-30 |
US20240150393A1 (en) | 2024-05-09 |
US11718642B2 (en) | 2023-08-08 |
WO2019140272A1 (fr) | 2019-07-18 |
TW201930269A (zh) | 2019-08-01 |
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