JPWO2020264411A5 - - Google Patents
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- Publication number
- JPWO2020264411A5 JPWO2020264411A5 JP2021577391A JP2021577391A JPWO2020264411A5 JP WO2020264411 A5 JPWO2020264411 A5 JP WO2020264411A5 JP 2021577391 A JP2021577391 A JP 2021577391A JP 2021577391 A JP2021577391 A JP 2021577391A JP WO2020264411 A5 JPWO2020264411 A5 JP WO2020264411A5
- Authority
- JP
- Japan
- Prior art keywords
- aav
- wash
- trishcl
- polysorbate
- wash buffer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962868282P | 2019-06-28 | 2019-06-28 | |
| US62/868,282 | 2019-06-28 | ||
| PCT/US2020/039971 WO2020264411A1 (en) | 2019-06-28 | 2020-06-26 | Adeno-associated virus purification methods |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2022539148A JP2022539148A (ja) | 2022-09-07 |
| JPWO2020264411A5 true JPWO2020264411A5 (https=) | 2023-05-25 |
| JP2022539148A5 JP2022539148A5 (https=) | 2023-05-25 |
| JP7539420B2 JP7539420B2 (ja) | 2024-08-23 |
Family
ID=74061311
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021577391A Active JP7539420B2 (ja) | 2019-06-28 | 2020-06-26 | アデノ随伴ウイルスの精製方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20220267796A1 (https=) |
| EP (1) | EP3990031A4 (https=) |
| JP (1) | JP7539420B2 (https=) |
| CN (1) | CN114173827B (https=) |
| TW (1) | TWI886135B (https=) |
| WO (1) | WO2020264411A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201628649A (zh) | 2014-10-09 | 2016-08-16 | 再生元醫藥公司 | 減少醫藥調配物中微可見顆粒之方法 |
| KR102369014B1 (ko) | 2016-08-16 | 2022-03-02 | 리제너론 파아마슈티컬스, 인크. | 혼합물로부터 개별 항체들을 정량하는 방법 |
| EA201990986A1 (ru) | 2016-10-25 | 2019-09-30 | Ридженерон Фармасьютикалз, Инк. | Способы и системы анализа хроматографических данных |
| WO2019060062A1 (en) | 2017-09-19 | 2019-03-28 | Regeneron Pharmaceuticals Inc. | METHODS OF REDUCING PARTICLE FORMATION AND COMPOSITIONS FORMED THEREFROM |
| TWI853823B (zh) | 2018-07-02 | 2024-09-01 | 美商里珍納龍藥品有限公司 | 自混合物製備多肽之系統及方法 |
| EA202192422A1 (ru) | 2019-03-05 | 2021-12-09 | Ридженерон Фармасьютикалз, Инк. | Человеческий сывороточный альбумин в составах |
| CN117716234A (zh) * | 2022-01-03 | 2024-03-15 | 科尔仕公司 | 用于从样本中分离阴电性低密度脂蛋白的生物试剂套组、试剂溶液以及从样本中分离阴电性低密度脂蛋白的方法 |
| US20230303983A1 (en) * | 2022-03-28 | 2023-09-28 | President And Fellows Of Harvard College | High efficiency purification of divergent aav serotypes using aavx affinity chromatography |
| WO2023189652A1 (ja) * | 2022-03-29 | 2023-10-05 | 株式会社カネカ | アデノ随伴ウイルスの製造方法 |
| CA3247416A1 (en) * | 2022-04-08 | 2023-10-12 | Csl Behring Ag | Methods of sanitizing and/or regenerating a chromatography medium |
| WO2024252024A1 (en) * | 2023-06-09 | 2024-12-12 | Sartorius Bia Separations D.O.O. | A method of enhanced separation of full adeno-associated virus (aav) capsids |
| EP4731755A2 (en) * | 2023-06-23 | 2026-04-29 | Ultragenyx Pharmaceutical Inc. | Compositions and methods for reducing host cell proteins in recombinant adeno-associated virus preparations |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7732129B1 (en) * | 1998-12-01 | 2010-06-08 | Crucell Holland B.V. | Method for the production and purification of adenoviral vectors |
| KR100912362B1 (ko) * | 1998-02-17 | 2009-08-19 | 쉐링 코포레이션 | 바이러스 제제의 정제방법 |
| US6593123B1 (en) * | 2000-08-07 | 2003-07-15 | Avigen, Inc. | Large-scale recombinant adeno-associated virus (rAAV) production and purification |
| CA2496918A1 (en) * | 2002-08-28 | 2004-03-11 | Introgen Therapeutics Inc. | Chromatographic methods for adenovirus purification |
| NZ548495A (en) * | 2004-02-23 | 2009-05-31 | Crucell Holland Bv | Virus purification methods |
| WO2006011580A1 (ja) * | 2004-07-27 | 2006-02-02 | Genomidea, Inc. | ウイルスエンベロープの精製方法 |
| WO2009123348A1 (ja) * | 2008-03-31 | 2009-10-08 | 日本たばこ産業株式会社 | ウイルス濃縮法 |
| EP3054007A1 (en) * | 2015-02-09 | 2016-08-10 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Recombinant adeno-associated virus particle purification comprising an immuno-affinity purification step |
| BR112018070256A2 (pt) * | 2016-03-31 | 2019-01-29 | Spark Therapeutics, Inc. | processo de fabricação de raav totalmente escalável à base de colunas |
| SG11202006232SA (en) * | 2017-12-29 | 2020-07-29 | Baxalta Inc | Adeno-associated virus purification methods |
-
2020
- 2020-06-26 EP EP20833341.9A patent/EP3990031A4/en active Pending
- 2020-06-26 WO PCT/US2020/039971 patent/WO2020264411A1/en not_active Ceased
- 2020-06-26 CN CN202080055070.0A patent/CN114173827B/zh active Active
- 2020-06-26 US US17/622,044 patent/US20220267796A1/en active Pending
- 2020-06-26 JP JP2021577391A patent/JP7539420B2/ja active Active
- 2020-06-29 TW TW109121962A patent/TWI886135B/zh active
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