JPWO2020256099A1 - - Google Patents

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Publication number
JPWO2020256099A1
JPWO2020256099A1 JP2021526915A JP2021526915A JPWO2020256099A1 JP WO2020256099 A1 JPWO2020256099 A1 JP WO2020256099A1 JP 2021526915 A JP2021526915 A JP 2021526915A JP 2021526915 A JP2021526915 A JP 2021526915A JP WO2020256099 A1 JPWO2020256099 A1 JP WO2020256099A1
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JP
Japan
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JP2021526915A
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Japanese (ja)
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JP7517704B2 (ja
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • C12N15/867Retroviral vectors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011Details
    • C12N2720/12011Reoviridae
    • C12N2720/12311Rotavirus, e.g. rotavirus A
    • C12N2720/12321Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011Details
    • C12N2720/12011Reoviridae
    • C12N2720/12311Rotavirus, e.g. rotavirus A
    • C12N2720/12322New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011Details
    • C12N2720/12011Reoviridae
    • C12N2720/12311Rotavirus, e.g. rotavirus A
    • C12N2720/12341Use of virus, viral particle or viral elements as a vector
    • C12N2720/12343Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00Nucleic acids vectors
    • C12N2800/22Vectors comprising a coding region that has been codon optimised for expression in a respective host

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2021526915A 2019-06-21 2020-06-19 外来遺伝子を安定的に保持する人工組換えrnaウイルスの作製方法 Active JP7517704B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2019115532 2019-06-21
JP2019115532 2019-06-21
PCT/JP2020/024131 WO2020256099A1 (ja) 2019-06-21 2020-06-19 外来遺伝子を安定的に保持する人工組換えrnaウイルスの作製方法

Publications (2)

Publication Number Publication Date
JPWO2020256099A1 true JPWO2020256099A1 (https=) 2020-12-24
JP7517704B2 JP7517704B2 (ja) 2024-07-17

Family

ID=74040505

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021526915A Active JP7517704B2 (ja) 2019-06-21 2020-06-19 外来遺伝子を安定的に保持する人工組換えrnaウイルスの作製方法

Country Status (5)

Country Link
US (1) US12305192B2 (https=)
EP (1) EP3988650A4 (https=)
JP (1) JP7517704B2 (https=)
CN (1) CN114040979B (https=)
WO (1) WO2020256099A1 (https=)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008507290A (ja) * 2004-08-03 2008-03-13 ジーンアート・アクチエンゲゼルシャフト 誘導性遺伝子発現
WO2018062199A1 (ja) * 2016-09-27 2018-04-05 国立大学法人大阪大学 人工組換えロタウイルスの作製方法
WO2018060368A2 (en) * 2016-09-28 2018-04-05 Bavarian Nordic A/S Compositions and methods for enhancing the stability of transgenes in poxviruses

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL140441A0 (en) * 1998-09-29 2002-02-10 Maxygen Inc Shuffling of codon altered genes
CN1934260B (zh) * 2004-01-22 2013-03-13 株式会社载体研究所 利用含有巨细胞病毒增强子和鸡β-肌动蛋白启动子的杂合启动子制造负链RNA病毒载体的方法
ATE453716T1 (de) 2004-08-03 2010-01-15 Geneart Ag Verfahren zur modulation der genexpression durch änderung des cpg gehalts
JP2009519715A (ja) * 2005-12-16 2009-05-21 ザ ユーエービー リサーチ ファウンデーション ウイルスベクターを使用する制御された遺伝子発現に関する組成物および方法
CN101245350B (zh) * 2007-02-17 2011-12-28 王健伟 密码子优化的轮状病毒蛋白的编码核苷酸序列、其重组体及其应用
KR101621100B1 (ko) * 2007-03-30 2016-05-13 더 리서치 파운데이션 오브 스테이트 유니버시티 오브 뉴욕 백신에 유용한 약독화 바이러스
GB0800272D0 (en) * 2008-01-08 2008-02-13 Plant Bioscience Ltd Protein expression systems
CN101502650B (zh) * 2009-03-10 2011-12-28 邢益平 密码子优化的乙型肝炎核酸疫苗
CN104862335A (zh) 2009-07-31 2015-08-26 诺华股份有限公司 反向遗传系统
TWI696700B (zh) * 2015-01-16 2020-06-21 國立研究開發法人產業技術總合研究所 使用具有匿跡性之rna的基因表現系統及含有該rna的基因導入、表現載體
CN104830874B (zh) * 2015-04-16 2017-11-21 南京医科大学第一附属医院 密码子优化的严重发热伴血小板减少综合征病毒核蛋白基因及其核酸疫苗
JP7054143B2 (ja) * 2016-05-11 2022-04-13 国立大学法人大阪大学 キメラ抗原受容体、及びその利用

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008507290A (ja) * 2004-08-03 2008-03-13 ジーンアート・アクチエンゲゼルシャフト 誘導性遺伝子発現
WO2018062199A1 (ja) * 2016-09-27 2018-04-05 国立大学法人大阪大学 人工組換えロタウイルスの作製方法
WO2018060368A2 (en) * 2016-09-28 2018-04-05 Bavarian Nordic A/S Compositions and methods for enhancing the stability of transgenes in poxviruses

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
APPL. ENVIRON. MICROBIOL., vol. vol.74, no.21, p.6538-6546, JPN6020032026, 2008, ISSN: 0005343856 *
APPL. MICROBIOL. BIOTECHNOL., vol. vol.98, p.3859-3867, JPN6020032025, 2014, ISSN: 0005343855 *
J. BIOTECHNOL., vol. vol.145, p.377-386, JPN6020032024, 2010, ISSN: 0005343854 *
MOL. THER., vol. vol.25, no.8, p.1854-1865, JPN6020032027, 2017, ISSN: 0005343857 *

Also Published As

Publication number Publication date
CN114040979B (zh) 2024-06-28
CN114040979A (zh) 2022-02-11
US20220356491A1 (en) 2022-11-10
EP3988650A1 (en) 2022-04-27
EP3988650A4 (en) 2022-09-21
US12305192B2 (en) 2025-05-20
JP7517704B2 (ja) 2024-07-17
WO2020256099A1 (ja) 2020-12-24

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